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| 1 | Skeletal Blood Flow in Bone Repair and Maintenance显示文摘Bone is a highly vascularized tissue,although this aspect of bone is often overlooked.In this article,the importance of blood flow in bone repair and regeneration will be reviewed.First,the skeletal vascular anatomy,with an emphasis on long bones,the distinct mechanisms for vascularizing bone tissue,and methods for remodeling existing vasculature are discussed.Next,techniques for quantifying bone blood flow are briefly summarized.Finally,the body of experimental work that demonstrates the role of bone blood flow in fracture healing,distraction osteogenesis,osteoporosis,disuse osteopenia,and bone grafting is examined.These results illustrate that adequate bone blood flow is an important clinical consideration,particularly during bone regeneration and in at-risk patient groups. | Ryan E.Tomlinson Matthew J.Silva | 2013 | Bone Research2013，1，4： | 12 |
| 2 | Depicting the battle between nectarine and Monilinia laxa:the fruit developmental stage dictates the effectiveness of the host defenses and the pathogen’s infection strategies显示文摘Infections by the fungus Monilinia laxa,the main cause of brown rot in Europe,result in considerable losses of stone fruit.Herein,we present a comprehensive transcriptomic approach to unravel strategies deployed by nectarine fruit and M.laxa during their interaction.We used M.laxa-inoculated immature and mature fruit,which was resistant and susceptible to brown rot,respectively,to perform a dual RNA-Seq analysis.In immature fruit,host responses,pathogen biomass,and pathogen transcriptional activity peaked at 14–24 h post inoculation(hpi),at which point M.laxa appeared to switch its transcriptional response to either quiescence or death.Mature fruit experienced an exponential increase in host and pathogen activity beginning at 6 hpi.Functional analyses in both host and pathogen highlighted differences in stage-dependent strategies.For example,in immature fruit,M.laxa unsuccessfully employed carbohydrate-active enzymes(CAZymes)for penetration,which the fruit was able to combat with tightly regulated hormone responses and an oxidative burst that challenged the pathogen’s survival at later time points.In contrast,in mature fruit,M.laxa was more dependent on proteolytic effectors than CAZymes,and was able to invest in filamentous growth early during the interaction.Hormone analyses of mature fruit infected with M.laxa indicated that,while jasmonic acid activity was likely useful for defense,high ethylene activity may have promoted susceptibility through the induction of ripening processes.Lastly,we identified M.laxa genes that were highly induced in both quiescent and active infections and may serve as targets for control of brown rot. | Marta Balsells-Llauradó Christian J.Silva Josep Usall Núria Vall-llaura Sandra Serrano-Prieto Neus Teixidó Saskia D.Mesquida-Pesci Antonieta de Cal Barbara Blanco-Ulate Rosario Torres | 2020 | Horticulture Research2020，7，1： | 1 |
| 3 | Consolidation of CS and US representations in associative fear conditioning显示文摘 | Paul W.Frankland Sheena A.Josselyn Stephan G.Anagnostaras Jeffrey H.Kogan EikiTakahashi Alcino J.Silva | 2004 | Hippocampus2004，，5： | 1 |
| 4 | Analysis of exosome release and its prognostic value in human colorectal cancer显示文摘 | J.Silva V.Garcia M.Rodriguez M.Compte E.Cisneros P.Veguillas J. M.Garcia G.Dominguez Y.Campos‐Martin J.Cuevas C.Pe?a M.Herrera R.Diaz N.Mohammed F.Bonilla | 2012 | Genes Chromosom Cancer2012，，4： | 1 |
| 5 | Alifanov迭代修正法估计非线性热传导未知热源函数显示文摘本文介绍热传导反问题中未知热源函数Alifanov迭代修正法估计的详细步骤;介绍了应用共轭梯度法的过程中,求解残差平方函数梯度的过程;并介绍了非线性估计的应用实例。 | 王甲正 张灿 Antonio J.Silva Neto Francisco D.Moura Neto | 2005 | 检验检疫科学2005，15，6： | 0 |
| 6 | A preliminary study of freshwater meiofaunal communities at Greenwich Island, South Shetland Islands, Antarctica显示文摘Meiofaunal communities of three small, shallow freshwater habitats sampled during the austral summer of 2013 in Greenwich Island, South Shetland Islands, Antarctica, are reported. Communities are dominated by tardigrades(85%), nematodes(11%), and rotifers(3%). Collembola, Oligochaeta, crustacean larvae(nauplii) and unidentified organisms account for 0.3%. Total meiofaunal densities reach 11 770 ind·cm-2, with mean densities(ind·cm-2) of 1 365.83 ± 2 716.65(Zone A), 523.67 ± 1 166.48(Zone B) and 72.17 ± 110.78(Zone C). Given the age of freshwater habitats, and the general lack of higher-trophic level predatory taxa, those species we report are likely early stage colonizers, and these communities are at an early stage of ecological succession. Non-parametrical analysis revealed the main variables influencing meiofaunal density and distribution are related to granulometric characteristics of sediments and microphytobenthic biomass. There were close relationships between meiofaunal abundance and microphytobenthic biomass, which indicates that benthic microalgae significantly influence meiofaunal distribution. A strong correlation between nematode abundance and the percentage of silt, clay and carbon in the sediment was also shown by canonical correspondence analysis and Spearman rank correlation. | Soraya J.Silva Minerva Cordovés Nory González Leinny González | 2015 | Advances in Polar Science2015，26，1： | 0 |
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