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| 1 | Consolidation and dynamics of 3D unsaturated porous seabed under rigid caisson breakwater loaded by hydrostatic pressure and wave显示文摘In this study,based on the dynamic Biot's theory 'u-p' approximation,a 3D finite element method(FEM) numerical soil model is developed,in which the Generalized Newmark-β method is adopted to determine the time integration.The developed 3D FEM soil model is a part of the coupled model PORO-WSSI 3D for 3D wave-seabed-marine structures interaction problem,and is validated by the analytical solution proposed by Wang(2000) for a laterally infinite seabed loaded by a uniform force.By adopting the developed 3D soil model,the consolidation of seabed under a caisson breakwater and hydrostatic pressure is investigated.The numerical results show that the caisson breakwater built on seabed has very significant effect on the stresses/displacements fields in the seabed foundation after the transient deformation and primary consolidation are completed.The parametric study indicates that the Young's modulus E of seabed is the most important parameter to affect the settlement of breakwater,and the displacement fields in seabed foundation.Taking the consolidation status as the initial condition,the interaction between ocean wave,caisson breakwater and seabed foundation is briefly investigated.The 3D ocean wave is determined by solving the Navier-Stokes equations with finite volume method(FVM).The numerical results indicate that there is intensive interaction between | YE JianHong JENG DongSheng CHAN A H C | 2012 | Science China(Technological Sciences)2012，55，8： | 4 |
| 2 | Triple ACE-ECE NEP inhibition in heart failure:a compareson with ACE and dual ECE-NEP inhibition显示文摘 | MELLIN V JENG A Y MONTEIL C | 2005 | J Cardiovasc Pharmacol2005，46，： | 1 |
| 3 | A MAC protocol for multi-channel multi-interface wireless mesh network using hybrid channel assignment scheme显示文摘 | Li C Jeng A and Jan R | 2007 | Journal of Information Science and Engineering2007，23，4： | 1 |
| 4 | The design, structure, and clinical update of small molecular weight matrix metalloproteinase inhibitors显示文摘 | Skiles J W Gonnella N C Jeng A Y | 2004 | Curr Med Chem2004，11，22： | 1 |
| 5 | The D eterm inates o fVenture C apital Fun din g: Evidence acro ss C oun ties 显示文摘 | Leslie A Jeng Philippe C Wells | 2000 | Journal o f Corporate Finance2000，9，6： | 1 |
| 6 | The Design, Structure, and Clinical Update of Small Molecular Weight Matrix Metatloproteinase Inlfibitons显示文摘 | Skiles J W Gonnella N C Jeng A Y | 2004 | Current Medicinal Chemistry2004，11，： | 1 |
| 7 | The determinants of venture capital funding:evidence across countries显示文摘 | LESLIE A JENG PHILIPPE C WELLS | 2000 | Journal of Corporate Finance2000，6，： | 1 |
| 8 | The determinants of venture capital funding: evidence across countries显示文摘 | JENG L A WELLS P C | 2000 | Journal of corporate Finance2000，6，3： | 1 |
| 9 | Use of autolo- gous serum eyedrops for the treatment of ocular surface disease: first US experience in a large population as an insurance-covered benefit 显示文摘 | Dalmon C A Chandra N S Jeng B H | 2012 | Arch Ophthalmol2012，130，12： | 1 |
| 10 | A new modular chemiluminescence immunoassay analyser evaluated 显示文摘 | Ognibene A Drake C J Jeng KY | 2000 | Clin Chem Lab Med2000，38，3： | 1 |
| 11 | The Determinants of Venture Capital Funding: Evidence Across Countries显示文摘 | JENG L A WELLS P C | 2000 | Journal of Corporate Finance2000，6，3： | 1 |
| 12 | Lipids in suspended matter and sediments from the East China Sea shelf显示文摘 | Jeng W L Huh C A | 2004 | Organic Geochemistry2004，35，5： | 1 |
| 13 | The determinants of venture capital funding:Evidence across countries显示文摘 | JENG L A WELLS P C | 2000 | Journal of Corporate Finance2000，6，： | 1 |
| 14 | Tranexamic acid for intracerebral haemorrhage within 2 hours of onset: protocol of a phase Ⅱ randomised placebo-controlled double-blind multicentre trial显示文摘Rationale Haematoma growth is common early after intracerebral haemorrhage(ICH),and is a key determinant of outcome.Tranexamic acid,a widely available antifibrinolytic agent with an excellent safety profile,may reduce haematoma growth.Methods and design Stopping intracerebral haemorrhage with tranexamic acid for hyperacute onset presentation including mobile stroke units(STOP-MSU)is a phase Ⅱ double-blind,randomised,placebo-controlled,multicentre,international investigator-led clinical trial,conducted within the estimand statistical framework.Hypothesis In patients with spontaneous ICH,treatment with tranexamic acid within 2 hours of onset will reduce haematoma expansion compared with placebo.Sample size estimates A sample size of 180 patients(90 in each arm)would be required to detect an absolute difference in the primary outcome of 20%(placebo 39%vs treatment 19%)under a two-tailed significance level of 0.05.An adaptive sample size re-estimation based on the outcomes of 144 patients will allow a possible increase to a prespecified maximum of 326 patients.Intervention Participants will receive 1 g intravenous tranexamic acid over 10 min,followed by 1 g intravenous tranexamic acid over 8 hours;or matching placebo.Primary efficacy measure The primary efficacy measure is the proportion of patients with haematoma growth by 24±6 hours,defined as either≥33%relative increase or≥6 mL absolute increase in haematoma volume between baseline and follow-up CT scan.Discussion We describe the rationale and protocol of STOP-MSU,a phase Ⅱ trial of tranexamic acid in patients with ICH within 2 hours from onset,based in participating mobile stroke units and emergency departments. | Nawaf Yassi Henry Zhao Leonid Churilov Bruce C V Campbell Teddy Wu Henry Ma Andrew Cheung Timothy Kleinig Helen Brown Philip Choi Jiann-Shing Jeng Annemarei Ranta Hao-Kuang Wang Geoffrey C Cloud Rohan Grimley Darshan Shah Neil Spratt Der-Yang Cho Karim Mahawish Lauren Sanders John Worthington Ben Clissold Atte Meretoja Vignan Yogendrakumar Mai Duy Ton Duc Phuc Dang Nguyen Thai My Phuong Huy-Thang Nguyen Chung Y Hsu Gagan Sharma Peter J Mitchell Bernard Yan Mark W Parsons Christopher Levi Geoffrey A Donnan Stephen M Davis | 2022 | Stroke & Vascular Neurology2022，7，2： | 1 |
| 15 | Erosion damage andsurface residual stress of Cr3C2/Al2C>3 composite显示文摘 | JENG C A HUANG J L LEE S Y | 2002 | MaterialsChemistry and Physics2002，78，1： | 1 |
| 16 | The determinants of venture capital funding: evidence across countries显示文摘 | Jeng L A Wells P C | 2000 | Journal of Corporate Finance2000，6，： | 1 |
| 17 | Serum lactate,not base deficit,rapidly predicts survival after major burns显示文摘 | Jeng J C Jablonski K Bridgeman A | 2002 | Burn2002，28，2： | 1 |
| 18 | Lipids in suspended matter and sediments from the East China Sea Shelf显示文摘 | Jeng W L Huh C A | 2004 | Organic Geochemistry2004，35，64： | 1 |
| 19 | Fatigue and R-curve behavior of an Al2O3-10vol%Cr3C2 composite 显示文摘 | Jeng C A Huang J L Wang S M | 2002 | J Mater Sci2002，37，： | 1 |
| 20 | Estrogens of multiple classes and their role in mental health disease mechanisms显示文摘 | Watson C S Alyea R A Cunningham K A Jeng Y J | 2010 | Int J Womens Health2010，9，： | 1 |
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