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| 1 | Metabolic complications in liver transplant recipients显示文摘The metabolic syndrome(MS), which includes obesity,dyslipidaemia, hypertension and hyperglycaemia according to the most widely accepted definitions now used, is one of the most common post-transplant complications, with a prevalence of 44%-58%. The MS, together with the immunosuppression, is considered the main risk factor for the development of cardiovascular disease(CVD) in transplant recipients, which in turn accounts for 19%-42% of all deaths unrelated to the graft. The presence of MS represents a relative risk for the development of CVD and death of 1.78. On the other hand, non-alcoholic fatty liver disease(NAFLD), considered as the manifestation of the MS in the liver, is now the second leading reason for liver transplantation in the United States after hepatitis C and alcohol. NAFLD has a high rate of recurrence in the liver graft and a direct relation with the worsening of other metabolic disorders, such as insulin resistance or diabetes mellitus. Consequently, it is vitally important to identify and treat as soon as possible such modifiable factors as hypertension, overweight, hyperlipidaemia or diabetes in transplanted patients to thus minimise the impact on patient survival. Additionally, steroid-free regimens are favoured, with minimal immunosuppression to limit the possible effects on the development of the MS. | Miguel Jiménez-Pérez Rocío González-Grande Edith Omonte Guzmán Víctor Amo Trillo Juan Miguel Rodrigo López | 2016 | World Journal of Gastroenterology2016，22，28： | 10 |
| 2 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 3 | Data-driven brain MRI segmentation supported on edge confidence and a priori tissue information显示文摘 | Jiménez-Alaniz J R Medina-Banuelos V Yánez-Suárez O | 2006 | IEEE Trans on Medical Imaging2006，25，1： | 1 |
| 4 | in vitro digestibility and allergenicity of emulsified hen egg显示文摘 | JIM(E)NEZ-SAIZ R RUIZ-HENESTROSA V L(O)PEZ-FANDI(N)OR | | 0，，02： | 1 |
| 5 | Elevated plasma endothelial microparticles: Preeclampsia versus gestational hypertension显示文摘 | Víctor H. González-Quintero Loren P. Smarkusky Joaquín J. Jiménez Lucía M. Mauro Wenche Jy Laurence L. Hortsman Mary J. O’Sullivan Yeon S. Ahn | 2004 | American Journal of Obstetrics and Gynecology2004，，4： | 1 |
| 6 | Growth and nutrient removal in free and immobilized lanktonic green algae isolated from pig manure显示文摘 | Jiménez-Pérez M V Sánchez-Castillo P Romera O | 2004 | Enzyme and Microbial Technology2004，，34： | 1 |
| 7 | Growth and nutrient removal in free and immobilized planktonic greenalgae isolated from pig manure显示文摘 | Jiménez-Pérez M V Sánchez-Castillo P Romerab O | 2004 | Enzyme and Microbial Technology2004，34，： | 1 |
| 8 | Further evidence of relation between prenatal famine and major affective disorder 显示文摘 | ALAN B JIM V O CORINE D | 2000 | Am J Psychiatry2000，157，： | 1 |
| 9 | Medicinal Plants, Precautions for Their Use in the Elderly显示文摘Objective:To relate physiologic changes and presence of illnesses in older adults,with the risk of appearance of adverse reactions and pharmacological interactions as consequence of the use of medicinal plants.Methods:To carry out a search in the last 5 years and to present a general vision about what have been published related to the use of medicinal plants with risk of appearance of adverse reactions and interactions in older adults.Conclusions:Technological prevision based on the search of articles in the Virtual Library in Health(BVS)and using the words key“medicinal plants”,“older adult”,“pharmacokinetics”,“adverse reactions”,“elderly”,“pharmacological interactions”,and the association among them. | Geuny Vázquez Bandomo Ana Elena Rodríguez Cadalso Regina de la Caridad Rodriguez MuñozI Eduardo Rafael Aguila Turiño Viviana Silvia Rodríguez Jiménez Reimundo Eugenio Fernández Abril | 2021 | Journal of Pharmacy and Pharmacology2021，9，4： | 0 |
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