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| 1 | Hepatocellular carcinoma: Review of disease and tumor biomarkers显示文摘Hepatocellular carcinoma(HCC) is a common malignancy and now the second commonest global cause of cancer death. HCC tumorigenesis is relatively silent and patients experience late symptomatic presentation. As the option for curative treatments is limited to early stage cancers, diagnosis in non-symptomatic individuals is crucial. International guidelines advise regular surveillance of high-risk populations but the current tools lack sufficient sensitivity for early stage tumors on the background of a cirrhotic nodular liver. A number of novel biomarkers have now been suggested in the literature, which may reinforce the current surveillance methods. In addition, recent metabonomic and proteomic discoveries have established specific metabolite expressions in HCC, according to Warburg's phenomenon of altered energy metabolism. With clinical validation, a simple and non-invasive test from the serum or urine may be performed to diagnose HCC, particularly benefiting low resource regions where the burden of HCC is highest. | Jin Un Kim Mohamed I F Shariff Mary M E Crossey Maria Gomez-Romero Elaine Holmes I Jane Cox Haddy K S Fye Ramou Njie Simon D Taylor-Robinson | 2016 | World Journal of Hepatology2016，8，10： | 13 |
| 2 | p38α controls erythroblast enucleation and Rb signaling in stress erythropoiesis显示文摘成红血球细胞的 Enucleation 对哺乳动物在终端区别期间唯一。尽管 erythroid enucleation 广泛地被学习了,包括 retinoblastoma 蛋白质(Rb ) ,仅仅一些基因被识别了调整原子挤出。它由哪个仍然保持大部分未定义发信号的分子,外来的刺激例如 erythropoietin (Epo ) ,是 transduced 导致 enucleation。这里,我们显示出那 p38α,激活 mitogen 的蛋白质 kinase (MAPK ) ,为 erythroid enucleation 被要求。在包含高 Epo 层次并且模仿的一个前 vivo 区别系统强调红血球生成, p38α在 erythroid 区别期间被激活。p38α 的损失;完全堵住主要成红血球细胞的 enucleation。而且, p38α在胎儿、贫血的压力红血球生成期间在 vivo 以一种房间自治的方式调整成红血球细胞 enucleation。显著地, p38α 的损失;导致 p21 目标 Rb 的 p21,和减少的激活的 downregulation,哪个是成红血球细胞 enucleation 的重要管理者。这研究表明那 p38α在压力红血球生成期间是为成红血球细胞 enucleation 的一个关键发信号分子。 | Simon M Schultze Andreas Mairhofer Dan Li Jin Cen Hartmut Beug Erwin F Wagner Lijian Hui | 2012 | Cell Research2012，22，3： | 2 |
| 3 | Isolation of new thermophilic aermostable α-amylase显示文摘 | Jin F X Cheng X M Shi Y F | 1990 | J Gen appl Microb1990，36，： | 1 |
| 4 | Oxidation behavior and breakdown of an aluminide coating on DZ40M alloy at high temperatures显示文摘 | Liu P S Liang K M Zhou H Y Guan H R Sun X F Jin T Yang K N | 2001 | Oxidation of Metals2001，55，56： | 1 |
| 5 | Loading-rate dependency ofuniaxial and indirect tensile strength 显示文摘 | Okubo S Jin F Akiyama M | 1993 | Journal of the Mining and Materials Processing Institute of Japan1993，109，11： | 1 |
| 6 | Downregulated long noncoding RNA MEG3 is associated with poor prognosis and promotes cell prolifer- ation in gastric cancer 显示文摘 | Sun M Xia R Jin F | 2014 | Tumour Biol2014，35，2： | 1 |
| 7 | Triple helix in the agricultural sector of Northeast Asian countries: a comparative study between Korea and China 显示文摘 | Kim H Huang M Jin F | 2012 | Scientometrics2012，90，1： | 1 |
| 8 | TLR3signaling in macrophages is indispensable for the protective immunity of invariant natural killer T cells against enterovirus 71infection显示文摘 | Zhu K Yang J Luo K Yang C Zhang N Xu R Chen J Jin M Xu B Guo N Wang J Chen Z Cui Y Zhao H Wang Y Deng C Bai L Ge B Qin C F Shen H Yang C F Leng Q | 2015 | PLoS Pathog2015，11，10： | 1 |
| 9 | Uric acid, hyperuricemia and vas- cular diseases显示文摘 | Jin M Yang F Yang I | 2012 | Front Biosci2012，1，17： | 1 |
| 10 | Structure of severe fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential显示文摘 | Jiao L Y Ouyang S Y Liang M F Niu F F Shaw N Wu W Ding W Jin C Peng Y Zhu Y P Zhang F S Wang T Li C Zuo X B Luan C H Li D X Liu Z J | 2013 | J Virol2013，87，12： | 1 |
| 11 | Polarization- independent metamaterial absorber for terahertz frequency显示文摘 | Kong H Li G F Jin Z M | 2012 | Journal of Infrared and Millimeter Waves2012，33，6： | 1 |
| 12 | Economical and green synthesis of bagasse-derived fluorescent carbon dots for biomedical applications 显示文摘 | Du F Y Zhang M M Li X F Li J N Jiang X Y Li Z Hua Y Shao G H Jin J Shao Q X | 2014 | Nanotechnology2014，25，31： | 1 |
| 13 | Partial hydrothermal oxidation ofunsaturated high molecular weight carboxylic acids for enhancing thecold flow properties of biodiesel fuel显示文摘 | Jin F M Xu Z Chen J L | 2010 | Fuel2010，89，： | 1 |
| 14 | Preparation and performance of nickle-tin alloys used as anodes for lithium-ion battery显示文摘 | DONG Q F WU C Z JIN M G | 2004 | Solide State Ionics2004，，167： | 1 |
| 15 | Determining the component number of links corresponding to lattices 显示文摘 | JIN X A DONG F M TAY E G | 2009 | J Knot Theor Ramif2009，18，12： | 1 |
| 16 | NIRF, a novel ubiquitin ligase, interacts with hepatitis B virus core protein and pro- motes its degradation显示文摘 | QIAN G H JIN F M CHANG L | 2012 | Biotechnology Letters2012，34，1： | 1 |
| 17 | Nonlinear coordinated control of excitation and governor for hydraulic power plants显示文摘 | Jin M J Hu W Liu F | 2005 | IEE Proceedings- Generation Transmission & Distribution2005，152，4： | 1 |
| 18 | How two ridges and the furrow mulched with plastic film affect soil water, soil temperature and yield of maize on the semiarid Loess Plateau of China显示文摘 | Zhou L M Li F M Jin S L | 2009 | Field Crops Research2009，113，1： | 1 |
| 19 | RM-MEDA: a regu larity model-based multiobjective estimation of distribu tion algorithm显示文摘 | Zhang Q F Zhou A M Jin Y C | 2008 | IEEE Trans on Evolutionary Corn putation2008，12，1： | 1 |
| 20 | Genetic analysis of conidiation regulatory pathways in koji mold As- pergillus oryzae 显示文摘 | Ogawa M Tokuoka M Jin F J | 2010 | Fungai genetics and biology2010，47，1： | 1 |
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