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| 1 | Serum MicroRNA Signatures Identified in a Genome-Wide Serum MicroRNA Expression Profiling Predict Survival of Non-Small-Cell Lung Cancer(摘要)显示文摘 | Hu, ZB Chen, X Zhao, Y Tian, T Jin, GF Shu, YQ Chen, YJ Xu, L Zen, K Zhang, CY Shen, HB | 2010 | 南京医科大学学报(自然科学版)2010，30，7： | 141 |
| 2 | Differential secretome analysis reveals CST6 as a suppressor of breast cancer bone metastasis显示文摘骨头转移从疾病是乳癌的经常的复杂并发症和病态和死亡的一个普通原因。在转移期间,分泌蛋白质在在癌症房间和主人基质之间的相互作用起关键作用。为了描绘分泌蛋白质,那与乳癌骨头转移被联系,我们比较四个 MDA-MB-231 (MDA231 ) 衍生物房间的 secretomes 的没有标签的 proteomic 分析与骨头转移的改变的能力衬里的 preformed。128 蛋白质的一个总数被发现是一致地在骨头回归线癌症房间的调节媒介的 up-/down-regulated。改变的蛋白质的充实的分子的函数包括了受体绑定和 peptidase 抑制。通过乳癌房间的另外的 transcriptomic 分析,我们选择了 cystatin E/M (CST6 ) ,在骨头变形的房间下面调整的一个半胱氨酸朊酶禁止者,为进一步功能的研究。我们的结果证明 CST6 压制了乳癌房间的增长,殖民地形成,迁居和侵略。对癌症房间活动性的镇压功能被癌症执行导出房间的可溶的 CST6。更重要地,在癌症房间的 CST6 的宫外的表示在动物学习救了老鼠免于公开 osteolytic 转移和死亡,当时 CST6 击倒的显著地提高的癌症房间骨头转移和弄短的动物幸存。总的来说,我们的学习提供了乳癌骨头向性的全身的 secretome 分析并且作为乳癌 osteolytic 转移的真正的 suppressor 建立了分泌 CST6。 | Lei Jin Yan Zhang Hui Li Ling Yao Da Fu Xuebiao Yao Lisa X Xu Xiaofang Hu Guohong Hu | 2012 | Cell Research2012，22，9： | 15 |
| 3 | Fracture of Aramid Fiber/Epoxy Resin Micro Composites显示文摘Kevlar-49 fiber was modified through cold air plasma treatment and plasma grafting with acrylic monomers. Fracture of aramid fiber/epoxy resin micro composites has been studied by means of single fiber pull-out test. Tow types of pull-out curves are correlated with the different failure modes. A polyacrylic acid-co-ethyl acrylate graft layer can improve the adhesion and protect the fiber from damage caused by interfacial stresses. | WANG, X ZHANG, CX JIN, SJ YU, YZ | 1995 | Journal of Materials Science & Technology1995，11，4： | 3 |
| 4 | Common non-synonymous polymorphisms in the BRCA1 Associated RING Domain (BARD1) gene are associated with breast cancer susceptibility:a case-control analysis显示文摘The BRCA1 Associated RING Domain(BARD1) gene has been identified as a high penetrance gene for breast cancer, whose germline and somatic mutations were reported in both non-BRCA1/2 hereditary site-specific and sporadic breast cancer cases. BARD1 plays a crucial role in tumor repression, along with its heterodimeric partner BRCA1. In the current study, we tested the hypothesis that common non-synonymous polymorphisms in BARD1 are associated with breast cancer susceptibility in a case-control study of 507 patients with incident breast cancer and 539 frequency-matched cancer-free controls in Chinese women. We genotyped all three common(minor allele frequency (MAF) > 0.10) non-synonymous polymorphisms(Pro24Ser, Arg378Ser, and Val507Met) in BARD1. We found that the BARD1 Pro24Ser variant genotypes(24Pro/Ser and 24Ser/Ser) and Arg378Ser variant homozygote 378Ser/Ser were associated with a significantly decreased breast cancer risk, compared with their wild-type homozygotes, respectively. Furthermore, a significant locus-locus interaction was evident between Pro24Ser and Arg378Ser (P-int = 0.032). Among the 378Ser variant allele carriers, the 24Pro/Pro wild-type homozygote was associated with a significantly increased breast cancer risk (adjusted OR = 1.81, 95% CI = 1.11-2.95), but the subjects having 24Pro/Ser or Ser/Ser variant genotypes had a significantly decreased risk(adjusted OR = 0.74, 95% CI = 0.56-0.99). In stratified analysis, this locus-locus interaction was more evident among subjects without family cancer history, those with positive estrogen receptor (ER) and individuals with negative progesterone receptor(PR). These findings indicate that the potentially functional polymorphisms Pro24Ser and Arg378Ser in BARD1 may jointly contribute to the susceptibility of breast cancer. | Huo, X Hu, Z. B Zhai, X. J Wang, Y Wang, S Wang, X. C Qin, J. W Chen, W. S Jin, G. F Liu, J. Y Gao, J Wei, Q. Y Wang, X. R Shen, H. B | 2007 | 南京医科大学学报(自然科学版)2007，27，7： | 3 |
| 5 | Measurements of γ/γ' Lattice Misfit and γ' Volume Fraction for a Ru-containing Nickel-based Single Crystal Superalloy显示文摘A conventional X-ray diffractometer has been used to determine the γ/γ lattice misfit and γ volume fraction for a Ru-containing nickel-based single crystal superalloy at room temperature.The rocking curve was used to characterize the distribution of subgrains.The diffraction peaks obtained by ω-2θ scan were used to determine the γ/γ lattice misfit and γ volume fraction.A three peaks fitting model was proposed.The peak fitting results are in good agreement with the model.The X-ray diffraction results indicate that the nickel-based single crystal superalloy was not a perfect monocrystalline material,which is comprised of many subgrains;and each subgrain also consists of large numbers of mosaic structures.In addition,two anomalous reflection phenomena were found during the experiment and discussed with respect to their occurrence and impact on the measurement.The experimental results show that the γ/γ lattice misfit and γ volume fraction will be various at the different regions of its dendritic microstructure.The average γ/γ lattice misfit and γ volume fraction of the experimental alloy are approximately-0.2% and 70%,respectively.Furthermore,the γ volume fraction calculated by atom microprobe(AP) data is also basically consistent with the experimental results. | X.P. Tan J.L. Liu X P Song T. Jin X.F. Sun Z.Q. Hu | 2011 | Journal of Materials Science & Technology2011，27，10： | 3 |
| 6 | Overview to the Hard X-ray Modulation Telescope (Insight-HXMT) Satellite显示文摘As China’s first X-ray astronomical satellite, the Hard X-ray Modulation Telescope (HXMT), which was dubbed as Insight-HXMT after the launch on June 15, 2017, is a wide-band(1-250 ke V) slat-collimator-based X-ray astronomy satellite with the capability of all-sky monitoring in 0.2-3 Me V. It was designed to perform pointing, scanning and gamma-ray burst(GRB)observations and, based on the Direct Demodulation Method (DDM), the image of the scanned sky region can be reconstructed.Here we give an overview of the mission and its progresses, including payload, core sciences, ground calibration/facility, ground segment, data archive, software, in-orbit performance, calibration, background model, observations and some preliminary results. | Shuang-Nan Zhang TiPei Li FangJun Lu LiMing Song YuPeng X u CongZhan Liu Yong Chen XueLei Cao QingCui Bu Zhi Chang Gang Chen Li Chen TianXiang Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong Yuan Yuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan Can Gungor ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge Ou JinLu Qu Na Sai RenCheng Shang GuoHong Shen Liang Sun Ying Tan Lian Tao YouLi Tuo Chen Wang ChunQin Wang GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BaiYang Wu BoBing Wu Mei Wu GuangCheng Xiao ShaoLin Xiong LinLi Yan JiaWei Yang Sheng Yang YanJi Yang QiBin Yi Bin Yuan AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang ShenYi Zhangs Shu Zhang Tong Zhang WanChang Zhang Wei Zhang WenZhao Zhang Yi Zhang YiFei Zhang YongJie Zhang Yue Zhang Zhao Zhang Zhi Zhang ZiLiang Zhang HaiSheng Zhao XiaoFan Zhao ShiJie Zheng JianFeng Zhou YuXuan Zhu Yue Zhu RenLin Zhuang | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，4： | 2 |
| 7 | Response of antioxidative enzymes in cucumber chloroplasts to cadmium toxicity显示文摘 | Zhang F Q Shi W Y Jin Z X | 2003 | J Plant Nutr2003，26，： | 2 |
| 8 | Relative frequency and survival of primary cutaneous lymphomas: a retrospective analysis of 98 patients显示文摘 | Liu J Liu YH Jin HZ Ma DL Qu T Wang T S un QN Yu X | 2014 | Chinese Medical Journal2014，，4： | 2 |
| 9 | BF4 : The first extended coordination network prepared solvothermally in an ionic liquid solvent 显示文摘 | Jin K Huang X Pang L | 2002 | Chem Commun2002，23，： | 1 |
| 10 | Circulant preconditioned WR-BVM methods for ODE systems 显示文摘 | Jin X Sin V Song L | 2004 | J Comput Appl Math2004，162，1： | 1 |
| 11 | Modern seismic methods in engineering investigation at a nuclear power plant site显示文摘 | Zhao Y G Jin H X Wang C F | 1996 | Scientia Geologica Sinica1996，5，4： | 1 |
| 12 | Endogenous hydrogen sulfide regulates pulmonary artery collagen remodeling in rats with high pulmonary blood flow 显示文摘 | Li X Jin H Bin G | 2009 | Experimental Biol Med2009，234，5： | 1 |
| 13 | A molecular mechanism regulating rhythmic output from the suprachiasmatic circadian clock显示文摘 | Jin X Shearman LP Weaver DR | 1999 | Cell1999，96，1： | 1 |
| 14 | Elevated phosphorylation of AKT and Stat3 in protate,breast,and cervical cancer cells显示文摘 | Page C Huang M Jin X | 2000 | Int J Oncol2000，17，1： | 1 |
| 15 | Isolation of new thermophilic aermostable α-amylase显示文摘 | Jin F X Cheng X M Shi Y F | 1990 | J Gen appl Microb1990，36，： | 1 |
| 16 | Microstructures and mechanical properties of ultrafine grained 7075 A1 alloy processed by ECAP and their evolutions during annea- ling显示文摘 | Zhao Y H Liao X Z Jin Z | 2004 | Acta Materialia2004，52，15： | 1 |
| 17 | An Integrated System for Automatic Road Mapping from High - - resolution Multi - spectral Satellite Imagery by Information Fusion 显示文摘 | Jin X Y Davis C H | 2005 | Information Fusion2005，6，4： | 1 |
| 18 | Microwave solid-state synthesis of spinel Li4Ti5O12 nanocrystallites as anode material for lithium-ion batteries显示文摘 | L1 J JIN Y L ZHANG X G | 2007 | Solid State lonics2007，178，： | 1 |
| 19 | Computational identification of novel family members of mieroRNA genes in Arabiopsis tha//ana and Oryza sativa显示文摘 | LI Y LI W JIN Y X | 2005 | Acta Biochmiea Biophysica Siniea (Shanghai)2005，37，2： | 1 |
| 20 | Estimating Risk of Foreign Exchange Portfolio: Using VaR and CVaR based on GARCH-EVT-Copula Model 显示文摘 | Wang Z R Chen X H Jin Y B Zhou Y J | 2010 | Physica A2010，，359： | 1 |
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