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| 1 | Unlocking re-flective practice for nurses: Innovations in working with masterof nursing students in Hong Kong显示文摘 | Joanne T Joyce - McCoach Dominique K | 2013 | Nurse Education in Prac-tice2013，，13： | 1 |
| 2 | Brain-derived neurotrophic factor(BDNF) prevents the degeneration of medial septal cholinergic neurons following fimbria transection显示文摘 | Joanne K Wiegand SJ Anderson K | 1993 | J Neurosci1993，13，10： | 1 |
| 3 | Problem-based learning and larger student groups:mutually exclusive or compatible conceptsa pilot study显示文摘 | Martyn P K Joanne S L | | 0，，35： | 1 |
| 4 | Fate and transport of antibiotic residues and antibiotic resistance genes following land application of manure waste 显示文摘 | Joanne C C Roderick I M Satoshi K | 2009 | Journal of Environmental Quality2009，38，3： | 1 |
| 5 | Relationship between epidemiological risk factors and hormone receptor expression in ovarian cancer: results from the nurses'health study显示文摘 | Jonathan L Joanne K Susan E | 2009 | Cancer Epidemiol Biomarkers Prey2009，18，5： | 1 |
| 6 | Root-derived respiration and nitrous oxide production as affected by crop phenology and nitrogen fertilization 显示文摘 | Benjamin K S Ameur M M Joann K W | 2010 | Plant and Soil2010，326，12： | 1 |
| 7 | Effect of glucose on 2,4-dinitrophenol degradation kinetics in sequencing batch reactors显示文摘 | Hess T F Silverstein JoAnn Steven K | 1993 | Water Environ Res1993，65，1： | 1 |
| 8 | Fresh from the pipeline: Gefitinib显示文摘 | Mohamed M Joanne G Peter K | 2003 | Nature Reviews Cancer2003，3，8： | 1 |
| 9 | Relationship between epi- demiological risk factors and hormone receptor expression in ovarian cancer:results from the nurses'health study 显示文摘 | Jonathan L Joanne K Susan E | 2009 | Cancer Epidemiol Biomarkers Prev2009，18，5： | 1 |
| 10 | Brain-derived neurotrophic factor(BDNF) prevents the degeneration of medial septal cholinergic neurons following fimbria transection显示文摘 | Joanne K Wiegand SJ Anderson K | 1993 | J Neurosci1993，13，10： | 1 |
| 11 | Serum outperforms plasma in small extracellular vesicle microRNA biomarker studies of adenocarcinoma of the esophagus显示文摘BACKGROUND Circulating microRNAs(miRNAs)are potential biomarkers for many diseases.However,they can originate from non-disease specific sources,such as blood cells,and compromise the investigations for miRNA biomarkers.While small extracellular vesicles(sEVs)have been suggested to provide a purer source of circulating miRNAs for biomarkers discovery,the most suitable blood sample for sEV miRNA biomarker studies has not been defined.AIM To compare the mi RNA profiles between matched serum and plasma s EV preparations to determine their suitability for biomarker studies.METHODS Matched serum and plasma samples were obtained from 10 healthy controls and10 patients with esophageal adenocarcinoma.s EV isolates were prepared from serum and plasma using Exo Quick TM and quantified using Nano Sight.RNA was extracted from s EV preparations with the mi RNeasy Serum/Plasma kit and profiled using the Taqman Openarray q PCR.The overall mi RNA content and theexpression of specific mi RNAs of reported vesicular and non-vesicular origins were compared between serum and plasma s EV preparations.The diagnostic performance of a previously identified multi-mi RNA biomarker panel for esophageal adenocarcinoma was also compared.RESULTS The overall mi RNA content was higher in plasma s EV preparations(480 mi RNAs)and contained 97.5%of the mi RNAs found in the serum s EV preparations(412 mi RNAs).The expression of commonly expressed mi RNAs was highly correlated(Spearman’s R=0.87,P<0.0001)between the plasma and serum s EV preparations,but was consistently higher in the plasma s EV preparations.Specific blood-cell mi RNAs(hsa-mi R-223-3 p,hsa-mi R-451 a,mi R-19 b-3 p,hsa-mi R-17-5 p,hsa-mi R-30 b-5 p,hsa-mi R-106 a-5 p,hsa-mi R-150-5 p and hsa-mi R-92 a-3 p)were expressed at 2.7 to 9.6 fold higher levels in the plasma s EV preparations compared to serum s EV preparations(P<0.05).In plasma s EV preparations,the percentage of protein-associated mi RNAs expressed at relatively higher levels(Ct 20-25)was greater than serum s EV preparations(50%vs 31%).While the percentage of vesicle-associated mi RNAs expressed at relatively higher levels was greater in the serum s EV preparations than plasma s EV preparations(70%vs 44%).A 5-mi RNA biomarker panel produced a higher cross validated accuracy for discriminating patients with esophageal adenocarcinoma from healthy controls using serum s EV preparations compared with plasma s EV preparations(AUROC 0.80 vs 0.54,P<0.05).CONCLUSION Although plasma s EV preparations contained more mi RNAs than serum s EV preparations,they also contained more mi RNAs from non-vesicle origins.Serum appears to be more suitable than plasma for s EV mi RNAs biomarkers studies. | Karen Chiam George C Mayne Tingting Wang David I Watson Tanya S Irvine Tim Bright Lorelle T Smith Imogen A Ball Joanne M Bowen Dorothy M Keefe Sarah K Thompson Damian J Hussey | 2020 | World Journal of Gastroenterology2020，26，20： | 1 |
| 12 | Foreign lan-+ guage classroom anxiety显示文摘 | Elaine K H Michael B H Joann C | 1986 | The Modern Language Journal1986，，2： | 1 |
| 13 | Long-term blood pressure control in a cohort of peritoneal dialysis patients and its association with residual renal function.显示文摘 | Murali K Menon David M Naimark Joanne M Bargman | | 0，，： | 1 |
| 14 | Intracellular cytokine expression of peripheral blood natural killer cell subsets in women with recurrent spontaneous abortions and implantation failures显示文摘 | Atsushi F Joanne K K Evangelos N | 2008 | Fertility and Sterility2008，89，1： | 1 |
| 15 | Movement of N from decomposing earthworm tissue to soil, microbial and plant N pools显示文摘 | JOANN K ROBERT W | 1999 | Soil Biol Biochem1999，31，： | 1 |
| 16 | Companionship and education : A nursing student experience in palliative care 显示文摘 | Kristine L K Cheryl V Joann E | 2005 | J Nurs Edu2005，44，4： | 1 |
| 17 | Impacts of earth-worms on soil nutrients and plant growth in soybean and maize agroecosystems 显示文摘 | Eriksen-Hamel N S Joann K W | 2007 | Agric Ecosyst Environ2007，120，24： | 1 |
| 18 | Simultaneous detection of antibodies to six nonhuman primate viruses by multiplex microbead immunoassay显示文摘 | Imran H K Sara M JoAnn Y | 2006 | Clinical and Vaccine Immunology2006，13，1： | 1 |
| 19 | Root-derived respiration and nitrous oxide production as affected by crop phenology and nitrogen fertilization显示文摘 | Benjamin K S Ameur M M Joann K W et a1 | 2010 | Plant and Soil2010，326，1： | 1 |
| 20 | Global Prevalence and major risk factors of diabetic retinopathy显示文摘 | Joanne WY Sophie L Ryo K | 2012 | Diabetes Care2012，35，3： | 1 |
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