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| 1 | Visceral hypersensitivity and electromechanical dysfunction as therapeutic targets in pediatric functional dyspepsia显示文摘Functional gastrointestinal disorders(FGID) are common clinical syndromes diagnosed in the absence of biochemical,structural,or metabolic abnormalities. They account for significant morbidity and health care expenditures and are identifiable across variable age,geography,and culture. Etiology of abdominal pain associated FGIDs,including functional dyspepsia(FD),remains incompletely understood,but growing evidence implicates the importance of visceral hypersensitivity and electromechanical dysfunction. This manuscript explores data supporting the role of visceral hypersensitivity and electromechanical dysfunction in FD,with focus on pediatric data when available,and provides a summary of potential therapeutic targets. | John M Rosen Jose T Cocjin Jennifer V Schurman Jennifer M Colombo Craig A Friesen | 2014 | World Journal of Gastrointestinal Pharmacology and Therapeutics2014，5，3： | 16 |
| 2 | Direct-fed microbes: A tool for improving the utilization of low quality roughages in ruminants显示文摘For many years, ruminant nutritionists and microbiologists have been interested in manipulating the microbial ecosystem of the rumen to improve production efficiency of different ruminant species. Removal and restriction of antibiotics subtherapeutic uses from ruminant diets has amplified interest in improving nutrient utilization and animal performance and search for more safe alternatives. Some bacterial and fungal microorganisms as a direct-fed microbial(DFM) can be the most suitable solutions. Microorganisms that are commonly used in DFM for ruminants may be classified mainly as lactic acid producing bacteria(LAB), lactic acid utilizing bacteria(LUB), or other microorganism's species like Lactobacillus, Bifidobacterium, Enterococcus, Streptococcus, Bacillus, Propionibacterium, Megasphaera elsdenii and Prevotellabryantii, in addition to some fungal species of yeast such as Saccharomyces and Aspergillus. A definitive mode of action for bacterial or fungal DFM has not been established; although a variety of mechanisms have been suggested. Bacterial DFM potentially moderate rumen conditions, and improve weight gain and feed efficiency. Fungal DFM may reduce harmful oxygen from the rumen, prevent excess lactate production, increase feed digestibility, and alter rumen fermentation patterns. DFM may also compete with and inhibit the growth of pathogens, immune system modulation, and modulate microbial balance in the gastrointestinal tract. Improved dry matter intake, milk yield, fat corrected milk yield and milk fat content were obtained with DFM administration. However, the response to DFM is not constant; depending on dosages, feeding times and frequencies, and strains of DFM. Nonetheless, recent studies have supported the positive effects of DFM on ruminant performance. | Mona M Y Elghandour Abdelfattah Z M Salem Jose S Martínez Castaeda Luis M Camacho Ahmed E Kholif Juan C Vázquez Chagoyán | 2015 | Journal of Integrative Agriculture2015，14，3： | 7 |
| 3 | Perioperative risk factors associated with delayed graft function following deceased donor kidney transplantation:A retrospective,single center study显示文摘BACKGROUND There is an abundant need to increase the availability of deceased donor kidney transplantation(DDKT)to address the high incidence of kidney failure.Challenges exist in the utilization of higher risk donor organs into what appears to be increasingly complex recipients;thus the identification of modifiable risk factors associated with poor outcomes is paramount.AIM To identify risk factors associated with delayed graft function(DGF).METHODS Consecutive adults undergoing DDKT between January 2016 and July 2017 were identified with a study population of 294 patients.The primary outcome was the occurrence of DGF.RESULTS The incidence of DGF was 27%.Under logistic regression,eight independent risk factors for DGF were identified including recipient body mass index≥30 kg/m^(2),baseline mean arterial pressure<110 mmHg,intraoperative phenylephrine administration,cold storage time≥16 h,donation after cardiac death,donor history of coronary artery disease,donor terminal creatinine≥1.9 mg/dL,and a hypothermic machine perfusion(HMP)pump resistance≥0.23 mmHg/mL/min.CONCLUSION We delineate the association between DGF and recipient characteristics of preinduction mean arterial pressure below 110 mmHg,metabolic syndrome,donorspecific risk factors,HMP pump parameters,and intraoperative use of phenylephrine. | Nicholas V Mendez Yehuda Raveh Joshua J Livingstone Gaetano Ciancio Giselle Guerra George W Burke III Vadim B Shatz Fouad G Souki Linda J Chen Mahmoud Morsi Jose M Figueiro Tony M Ibrahim Werviston L DeFaria Ramona Nicolau-Raducu | 2021 | World Journal of Transplantation2021，11，4： | 2 |
| 4 | Comparison of different sample treatments for the analysis of ochratoxin A in must, wine and beer by liquid chromatography显示文摘 | SAEZ J M MEDINA A JOSE V | 2004 | Journal of Chromatography A2004，1029，： | 1 |
| 5 | Diminished insulin receptors on erythrocyte ghosts in nonobese patients with essential hypertension independent of hyperinsulinemia显示文摘 | MIGUEL V JOSE A L | 1994 | J Cardiovasc Pharmacol1994，24，： | 1 |
| 6 | Awireless controller to enhance dynamic performance of parallel inverters in distributed generation system显示文摘 | Guerrero J M Luis Garcia de V Jose M | 2004 | IEEE Transactions on Power Electronics2004，19，5： | 1 |
| 7 | Effect of immobilization on the catalytic properties of ferredoxin-nitrite reductase from cblamydomonas reinhardi II 显示文摘 | JOSE L FRANCISCO G JOSE M V | 1990 | Journal of Molecular Catalysis1990，58，： | 1 |
| 8 | Antimicrobial susceptibility of clinical strains of Streptococcus suis isolated from pigs in Spain 显示文摘 | Ana 1 V Miguel A M Jose'A C | 2005 | Veterinary Microbiology2005，105，： | 1 |
| 9 | Loureiro Number of Actives Sites in TAME Synthesis: Mechanism and Kinetic Modeling显示文摘 | Manuela V Ferreira Jose M | 2004 | Ind Eng Chem Res2004，，43： | 1 |
| 10 | A broadbandCMOS amplitude detector for on-chip RF measure*ments显示文摘 | Alberto V G Radhika V Jose S M | 2008 | IEEE Transactions on Instrumentation andMeasurement2008，57，7： | 1 |
| 11 | Photocatalytic water splitting on Au/TiO2 nanocomposites synthesized through various routes:Enhancement in photocatalytic activity due to SPR effect显示文摘 | Sadhana S R Jose D Joshi M V | | 0，，： | 1 |
| 12 | Calculation of electric field and potential distributions into soil and air media for a ground electrode of a HVDC system显示文摘 | Jose E T V Carlos M P | 2003 | IEEE Transactions on Power Delivery2003，18，3： | 1 |
| 13 | Nanostructured Nb2O5 polymorphs by electrospinning for rechargeable lithium batterries显示文摘 | VIET A L REDDY M V JOSE R | 2010 | The Journal of Physical Chemistry C2010，114，1： | 1 |
| 14 | A wireless controller to enhance dynamic performance of parallel inverters in distributed generation system显示文摘 | GUERRERO J M LUIS GARCIA D E V JOSE M | 2004 | IEEE Transactions on Power Electronics2004，19，5： | 1 |
| 15 | Optical studies of nano-structured La-doped ZnO prepared bycombustion method 显示文摘 | JOSE L A LINET J M SIVASUBRAMANIAN V | 2012 | Materials Science in SemiconductorProcessing2012，15，3： | 1 |
| 16 | Spatial distribution of forest fires in Sierra de Gredos (Central Spain) 显示文摘 | Antonio V Jose M M | 2001 | Forest Ecology and Management2001，147，： | 1 |
| 17 | An indoor localization system based on artificial neural networks and particle filters applied to intelligent buildings 显示文摘 | Moreno-Cano M V Zamora-Izquierdo M A Santa Jose | 2013 | Neurocomputing2013，122，： | 1 |
| 18 | Influence of the size of aortic valve prostheses on hemodynamics and change in left ventricular mass: implications for the surgical menagement of aortic stenosis显示文摘 | JOSE R C J JOSE M G A MARINO V F | 1996 | J Thorac Cardiovasc Surg1996，112，1： | 1 |
| 19 | The interleukin-6(174) G/C promoter polymorphism in associated with type 2 diabetes mellitus in native americans and caucasians显示文摘 | BARBORA V JOSE M FERNANDEZ-REALWILLIAM C | 2003 | Hum Genet2003，112，： | 1 |
| 20 | Combined pyrolysis combustion cycle: effects of operating condition on sulfur and calorific value distribution in coal pyrolysis显示文摘 | Rafael Moliner Jose'V lbaara M J Lazaro | 1994 | Fuel1994，73，7： | 1 |
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