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38篇 您的检索式:作者名="Jadus"
    题名 作者 年代 出处 被引量
1膜型巨噬细胞集落刺激因子对人脑胶质细胞瘤的免疫治疗作用显示文摘摘要 目的 探讨基因转染膜型巨噬细胞集落刺激因子(mM-CSF)对U251MG人脑胶质瘤细胞的免疫治疗作用。方法 用逆转录病毒载体将mM-CSF基因转入U251MG细胞,采用流式细胞术检测mM-CSF的表达;通过细胞毒性实验、兔疫组化方法以及观察转染细胞在免疫缺陷小鼠体内的生长情况研究mM-CSF对U251MG细胞的作用。结果①获得了表达mM-CSF的MG-2F11细胞;②大鼠巨噬细胞、人外周血淋巴细胞(PBL)和人单核细胞均可杀伤MG-2F11细胞,但不能杀伤U251MG母细胞;③接种瘤细胞到裸小鼠皮下18 h后,侵入MG-2F11肿瘤的巨噬细胞明显多于侵入MG-VV(仅转染病毒载体的U251MG细胞)肿瘤的巨噬细胞;④接种MG-2F11细胞的8只裸小鼠均无肿瘤生长,而接种MG-VV细胞的8只裸小鼠中的7只有肿瘤生长(P<0.01);另一免疫缺陷更严重的NIH-bg-nu-xidBR 小鼠,接种MG-2F11细胞后8只中的1只有肿瘤生长,而接种MG-VV细胞后8只中的7只有肿瘤生长(P<0.01)。结论mM-CSF转染的人脑胶质瘤细胞致瘤性降低,有进一步对其进行临床研究的必要。陈义军 Cheri Lloyd Ramon Sanchez Martin R Jadus H Terry Wepsic 2002中华神经外科疾病研究杂志2002,1,3:2
2Risk factors for non communicable diseases:methods and global results of the CARMEN program basal survey显示文摘Jadue L Vega J Escobar MC 1999Rev Med Chil1999,127,8:1
3A comparison of the bronchodilating effects of a beta-2 adrenergic agent(albuterol) and an anticholinergic agent (ipratropium bromide) , given by aerosol alone or in sequence显示文摘Easton PA Jadue C Dhingra S 1986N EngI J Med1986,315,12:1
4Human U251MG glioma cells expressing the membrane form of macrophage colony-stimulating factor(m M-CSF)are killed by human monocytes in vitro and are rejected within immunodeficient mice via paraptosis that is associated with increased expression of three different heat shock proteins显示文摘Jadus MR Chen Y Boldaji MT 2003Cancer Gene Therapy2003,10,5:1
5Lung cancer: a classic example of tumor escape and progression while providing opportunities for immunological intervention显示文摘Jadus MR NatividadJ Mai A 2012Clin Dev Immunol2012,2012,16:1
6DNA isolation and AFLP fingerprinting of nectarine and peach varieties(Prunus persica)显示文摘Manubens A Lobos S Jadue Y 1999Plant Molecular Biology Reporter1999,17,3:1
7Intrapleural injec-tion of transforming growth factor - beta antibody inbibits pleural fi- brosis in empyema显示文摘KUNZ C R JADUS M R KUKES G D 2004Chest2004,126,5:1
8The role of cytokines in graft-versus-host reactions and disease显示文摘Jadus MR Wepsic HT 1992Bone Marrow Transplant1992,10,1:1
9Temperature dependence of Q and inductance in spiral inductors fabricated in a silicon-germanium/BiCMOS technology显示文摘GROVES R HARAME D L JADUS D 1997IEEE J Solid-State Circuits1997,32,9:1
10Gene expression and gene therapy in experimental duodenal ulceration显示文摘Sandor Szabo Xiaoming Deng Tetyana Khomenko Masashi Yoshida Martin R Jadus Zsuzsa Sandor Zoltan Gombos Hiroko Matsumoto 2001Journal of Physiology - Paris2001,,1:1
11Human U251MG glioma cells expressing the membrane form of macrophage colony-stimulating factor(mM-CSF) are killed by human monocytes in vitro and are rejected within immunodeficicnt mice via paraptosis that is associated with increased expression of three different heatshock proteins显示文摘Jadus MR Chen Y Boldaji MT 2003Cancer Gene Ther2003,10,5:1
12DNA isolation and AFLP fingerprinting of nectarine and peach varieties(Prunus persica)显示文摘Manubens A Lobos S Jadue Y Toro M Messina R Lladser M Seelenfreund D 0,,03:1
13The role of eytokines in graft-versus-host reactions and disease显示文摘Jadus M R Wepsie H T 1992Bone Marrow Transplant1992,10,1:1
14Lung cancer: a classic example of tumor escape and progression while providing opportunities for immunological intervention显示文摘Jadus MR Natividad J Mai A 2012Clin Dev Immunol2012,2012,16:1
15Pleural fluid transforming growth factor-betal correlates with pleural fibrosis in experimental empyema 显示文摘Sasse SA Jadus MR Kukes GD 2003Am J Resp Crit Care Med2003,168,6:1
16Intrapleural injection of transforming growth factor-beta antibody inhibits pleural fibrosis in empyema显示文摘Kunz CR Jadus MR Kukes GD 2004Chest2004,126,5:1
17Intrapleural injection of transforming growth factor-beta antibody inhibits pleural fibrosis in empyema 显示文摘Kunz CR Jadus MR Kukes GD 2004Chest2004,126,3:1
18Intrapleural injection of transforming growth factor-beta antibody inhibits pleural fibrosis in empyema显示文摘Kunz CR Jadus MR Kukes GD 2004Chest2004,126,5:1
19Effect of cysteamine on redox-sensitive thiol-containing proteins in the duodenal mucosa显示文摘Khomenko T Deng X Jadus M R 2003Biochem Biophys Res Commun2003,309,4:1
20Effect of cysteamine on redox-sensitive thiol-containing proteins in the duodenal mucosa显示文摘Khomenko T Deng X Jadus M R Szabo S 2003Biochemical and Biophysical Research Communication2003,309,4:1
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