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| 1 | Prevalence of clonorchiasis in patients with gastrointestinal disease: A Korean nationwide multicenter survey显示文摘AIM: To investigate prevalence of Clonorchis sinensis in patients with gastrointestinal symptoms, and the relation of the infection to hepatobiliary diseases in 26 hospitals in Korea.METHODS: Consecutive patients who had been admitted to the Division of Gastroenterology with gastrointestinal symptoms were enrolled from March to April 2005. Of those who had been diagnosed with clonorchiasis, epidemiology and correlation between infection and hepatobiliary diseases were surveyed by questionnaire.RESULTS: Of 3080 patients with gastrointestinal diseases, 396 (12.9%) had clonorchiasis and 1140 patients (37.2%) had a history of eating raw freshwater fish. Of those with a history of raw freshwater fish ingestion, 238 (20.9%) patients had clonorchiasis. Cholangiocarcinoma was more prevalent in C. sinensis-infected patients than non-infected patients [34/396 (8.6%) vs 145/2684 (5.4%), P = 0.015]. Cholangiocarcinoma and clonorchiasis showed statistically significant positive cross-relation (P = 0.008). Choledocholithiasis, cholecystolithiasis, cholangitis, hepatocellular carcinoma, and biliary pancreatitis did not correlate with clonorchiasis.CONCLUSION: Infection rate of clonorchiasis was still high in patients with gastrointestinal diseases in Korea, and has not decreased very much during the last two decades. Cholangiocarcinoma was related to clonorchiasis, which suggested an etiological role for the parasite. | Ho Gak Kim Jimin Han Myung-Hwan Kim Kyu Hyun Cho Im Hee Shin Gwang Ha Kim Jae Seon Kim Jin Bong Kim Tae Nyeun Kim Tae Hyeon Kim Tae Hyo Kim Jae Woo Kim Ji Kon Ryu Young-Soo Moon Jong Ho Moon Sung Jae Park Chan Guk Park Sung-Jo Bang Chang Heon Yang Kyo-Sang Yoo Byung Moo Yoo Kyu Taek Lee Dong Ki Lee Byung Seok Lee Sang Soo Lee Seung Ok Lee Woo Jin Lee Chang Min Cho Young-Eun Joo Gab Jin Cheon Young Woo Choi Jae Bok Chung Yong Bum Yoon | 2009 | World Journal of Gastroenterology2009，15，1： | 15 |
| 2 | Prognostic value of inflammation-based markers in patients with pancreatic cancer administered gemcitabine and erlotinib显示文摘AIM: To evaluate the value of systemic inflammationbased markers as prognostic factors for advanced pancreatic cancer(PC). METHODS: Data from 82 patients who underwent combination chemotherapy with gemcitabine and erlotinib for PC from 2011 to 2014 were collected retrospectively. Data that included the neutrophil-to-lymphocyte ratio(NLR), the platelet-to-lymphocyte ratio, and the C-reactive protein(CRP)-to-albumin(CRP/Alb) ratio were analyzed. Kaplan-Meier curves, and univariate and multivariate Cox proportional hazards regression analyses were used to identify the prognostic factors associated with progression-free survival(PFS) and overall survival(OS). RESULTS: The univariate analysis demonstrated the prognostic value of the NLR(P = 0.049) and the CRP/Alb ratio(P = 0.047) in relation to PFS, and a positiverelationship between an increase in inflammation-based markers and a poor prognosis in relation to OS. The multivariate analysis determined that an increased NLR(hazard ratio = 2.76, 95%CI: 1.33-5.75, P = 0.007) is an independent prognostic factor for poor OS. There was no association between the PLR and the patients' prognoses in those who had received chemotherapy that comprised gemcitabine and erlotinib in combination. The Kaplan-Meier method and the log-rank test determined significantly worse outcomes in relation to PFS and OS in patients with an NLR > 5 or a CRP/Alb ratio > 5.CONCLUSION: Systemic inflammation-based markers, including increases in the NLR and the CRP/Alb ratio, may be useful for predicting PC prognoses. | Jae Min Lee Hong Sik Lee Jong Jin Hyun Hyuk Soon Choi Eun Sun Kim Bora Keum Yeon Seok Seo Yoon Tae Jeen Hoon Jai Chun Soon Ho Um Chang Duck Kim | 2016 | World Journal of Gastrointestinal Oncology2016，8，7： | 12 |
| 3 | Risk factors of organ failure in cholangitis with bacteriobilia显示文摘AIM: To identify the risk factors for organ failure(OF) in cholangitis with bacteriobilia.METHODS: This study included 182 patients with acute cholangitis who underwent percutaneous transhepatic biliary drainage between January 2005 and April 2013. We conducted a retrospective analysis of comprehensive clinical and laboratory data.RESULTS: There were 24 cases(13.2%) of OF and five deaths(2.7%). Bile culture was positive for microbial growth in 130 out of 138(94.2%) patients. In multivariate analysis of 130 patients with positivebile cultures, significant predictive factors for OF were the presence of extended-spectrum beta-lactamase(ESBL) organisms in blood cultures, pre-existing renal dysfunction, and choledocholithiasis as an etiology, with odds ratios of 15.376, 6.319, and 3.573, respectively. We developed a scoring system with a regression coefficient of each significant variable. The OF score was calculated using the following equation:(2.7 × ESBL organisms in blood cultures) +(1.8 × pre-existing renal dysfunction) +(1.3 × choledocholithiasis). This scoring system for predicting OF was highly specific(99.1%) and had a positive predictive value of 86.2%.CONCLUSION: ESBL organisms in blood cultures, preexisting renal dysfunction, and choledocholithiasis are risk factors for OF in cholangitis with bacteriobilia. The OF scoring system may aid clinicians to identify a poor prognosis group. | Jae Min Lee Sang Hyub Lee Kwang Hyun Chung Jin Myung Park Ban Seok Lee Woo Hyun Paik Joo Kyung Park Ji Kon Ryu Yong-Tae Kim | 2015 | World Journal of Gastroenterology2015，21，24： | 8 |
| 4 | Anxiety and depression propensities in patients with acute toxic liver injury显示文摘AIM:To investigate anxiety and depression propensities in patients with toxic liver injury.METHODS:The subjects were divided into three groups:a healthy control group(Group 1,n=125),an acute non-toxic liver injury group(Group 2,n=124),and a group with acute toxic liver injury group caused by noncommercial herbal preparations(Group 3,n=126).These three groups were compared and evaluated through questionnaire surveys and using the Hospital Anxiety-Depression Scale(HADS),Beck Anxiety Inventory(BAI),Beck Depression Inventory(BDI),and the hypochondriasis scale.RESULTS:The HADS anxiety subscale was 4.9±2.7,5.0±3.0 and 5.6±3.4,in Groups 1,2,and 3,respectively.The HADS depression subscale in Group 3 showed the most significant score(5.2±3.2,6.4±3.4 and 7.2±3.4in Groups 1,2,and 3,respectively)(P<0.01 vs Group 1,P<0.05 vs Group 2).The BAI and BDI in Group 3showed the most significant score(7.0±6.3 and 6.9±6.9,9.5±8.6 and 8.8±7.3,10.7±7.2 and 11.6±8.5in Groups 1,2,and 3,respectively)(BAI:P<0.01 vs Group 1,P<0.05 vs Group 2)(BDI:P<0.01 vs Group1 and 2).Group 3 showed a significantly higher hypochondriasis score(8.2±6.0,11.6±7.5 and 13.1±6.5in Groups 1,2,and 3,respectively)(P<0.01 vs Group 1,P<0.05 vs Group 2).CONCLUSION:Psychological factors that present vulnerability to the temptation to use alternative medicines,such as herbs and plant preparations,are important for understanding toxic liver injury. | Jeong Ill Suh Jeong Kyu Sakong Kwan Lee Yong Kook Lee Jeong Bae Park Dong Joon Kim Yeon Seok SeoDepartment of Internal Medicine Korea University Anam Hospital Korea University College of Medicine Seoul 136-705 South Korea Jae Dong Lee Soon Young Ko Byung Seok Lee Seok Hyun Kim Byung Seok Kim Young Seok Kim Heon Ju Lee In Hee Kim Joo Hyun Sohn Tae Yeob Kim Byung Min Ahn | 2013 | World Journal of Gastroenterology2013，19，47： | 5 |
| 5 | Duodenal variceal bleeding after balloon-occluded retrograde transverse obliteration: Treatment with transjugular intrahepatic portosystemic shunt显示文摘We report a case of duodenal varix bleeding as a long term complication of balloon occluded retrograde transvenous obliteration (BRTO), which was successfully treated with a transjugular intrahepatic portosystemic shunt (TIPS). A 57-year-old man was admitted to the emergency room suffering from melena. He had under-gone BRTO to treat gastric varix bleeding 5 mo before admission. Endoscopy and a computed tomography (CT) scan showed complete obliteration of the gastric varix, but the nodular varices in the second portion of the duodenum expanded after BRTO, and spurting blood was seen. TIPS was performed for treatment of duodenal variceal bleeding, because attempts at endoscopic varix ligation were unsuccessful. The post-operative course was uneventful and the patient was discharged without complications. A follow up CT scan obtained 21 mo after TIPS revealed a patent TIPS tract and complete obliteration of duodenal varices, but multinodular hepatocellular carcinoma had developed. He died of hepatic failure 28 mo after TIPS. | Min Joung Kim Byoung Kuk Jang Woo Jin Chung Jae Seok Hwang Young Hwan Kim | 2012 | World Journal of Gastroenterology2012，18，22： | 3 |
| 6 | 微波辐射辅助柠檬酸络合法制备的Ho^(3+)/Tm^(3+)/Yb^(3+)共掺杂CaWO_4的白光性能(英文)显示文摘采用微波辐射辅助柠檬酸络合法制备Ho3+/Tm3+/Yb3+共掺杂CaWO4纳米晶升频转换荧光粉。将柠檬酸络合物前驱体在300~700°C热处理3 h。Ho3+/Tm3+/Yb3+共掺杂CaWO4C在400°C时开始结晶,在600°C时结晶完成。经600°C热处理的Ho3+/Tm3+/Yb3+共掺杂CaWO4主要呈球形,且形态均匀。在980 nm的激光激发下,Ho3+/Tm3+/Yb3+共掺杂CaWO4纳米晶出现肉眼可见的明亮的白色升频转换发射,这种现象来自Tm3+的475 nm蓝光发射以及Ho3+的543 nm绿光和651 nm红光发射。通过调整Tm3+和Ho3+的浓度可以控制Ho3+/Tm3+/Yb3+共掺杂CaWO4的CIE色度图从冷到暖白色之间变化。讨论了Tm3+和Ho3+浓度对升频转换光性能的影响以及与激光泵功率相关的影响机制。 | Hyun CHO Seok Min HWANG Jae Bin LEE Dong Hyun KA Tae Wan KIM Bo Seul LEE Ji Young LEE Jung-Il LEE Jeong Ho RYU | 2014 | Transactions of Nonferrous Metals Society of China2014，24，S1： | 2 |
| 7 | Saccular damage in patients with idiopathic sudden sensorineural hearing loss without vertigo显示文摘 | Seok Min Hong Jae Yong Byun Chan Hum Park Jun Ho Lee Moon Suh Park Chang Il Cha | 2008 | Otolaryngology - Head and Neck Surgery2008，，4： | 1 |
| 8 | The Effects of Proteinuria on Urinary Cystatin-C and Glomerular Filtration Rate Calculated by Serum Cystatin-C显示文摘 | Jae Seok Kim Min Keun Kim Jun Young Lee Byoung Geun Han Seung Ok Choi Jae Won Yang | 2012 | Renal Failure2012，，6： | 1 |
| 9 | Combustion performance test of a new fuel DME to adapt to a gas turbine for power generation显示文摘 | Min Chul Lee Seok Bin Seo Jae Hwa Chung | 2008 | Fuel2008，，87： | 1 |
| 10 | A Randomized, Multi-Center, Clinical Trial to Assess the Efficacy and Safety of Alginate Carboxymethylcellulose Hyaluronic Acid Compared to Carboxymethylcellulose Hyaluronic Acid to Prevent Postoperative Intrauterine Adhesion显示文摘 | Tak Kim Ki Hoon Ahn Doo Seok Choi Kyung Joo Hwang Byoung Ick Lee Min Hyung Jung Jae Weon Kim Jong Hyuk Kim Sun Hee Cha Ki Hwan Lee Kyu Sup Lee Sung Tack Oh Chi Heum Cho Jeong Ho Rhee | 2012 | The Journal of Minimally Invasive Gynecology2012，，6： | 1 |
| 11 | Non-invasive assessment of changes in liver fibrosis via liver stiffness measurement in patients with chronic hepatitis B: impact of antiviral treatment on fibrosis regression显示文摘 | Seung Up Kim Jun Yong Park Do Young Kim Sang Hoon Ahn Eun Hee Choi Jae Yeon Seok Jung Min Lee Young Nyun Park Chae Yoon Chon Kwang-Hyub Han | 2010 | Hepatology International2010，，4： | 1 |
| 12 | A randomized, prospective trial on efficacy and tolerability of low-volume bowel preparation methods for colonoscopy显示文摘 | In Kyung Yoo Jong Soo Lee Hoon Jai Chun Yoon Tae Jeen Bora Keum Eun Sun Kim Hyuk Soon Choi Jae Min Lee Seung Han Kim Seung Joo Nam Hyo Sung Kang Hong Sik Lee Chang Duck Kim Soon Ho Um Yeon Seok Seo Ho Sang Ryu | 2014 | Digestive and Liver Disease2014，，： | 1 |
| 13 | Relationship between coronary artery plaque composition by virtual histology intravascular ultrasound analysis and brachial-ankle pulse wave velocity in patients with coronary artery disease显示文摘 | Jee Eun Kwon Gary S. Mintz Sang-Wook Kim Min Seok Oh Yun Ju Min Hyang Kyoung Kim Jae Seung Seo Wang Soo Lee Kwang Je Lee Tae Ho Kim Chee Jeong Kim Dai Yun Cho Wang Seong Ryu | 2011 | Coronary Artery Disease2011，，8： | 1 |
| 14 | Hemorrhagic hemangioma in the liver:A case report显示文摘Hemangioma is the most common type of benign tumor that arises in the liver. Although rupture and hemorrhage of hepatic hemangioma are rare complications, they can be the cause of mortality. The authors report a case of hemorrhagic hepatic hemangioma: in a 54-yearold woman who was admitted with epigastric pain.She had taken oral contraceptives several weeks prior.The results of a blood examination were normal. An abdominal computed tomography scan revealed a tumor in hepatic segment 4, and a hemorrhage inside the cystic mass was suspected. The mass was removed laparoscopically to confirm the tumor properties and control the hemorrhage. The pathologic findings of the resected mass were consistent with hepatic hemangioma with intratumoral hemorrhage. The patient was discharged 8 d after the surgery, without further complications or complaints, and the patient's condition was found to have improved during follow-up. | Jeong Min Kim Woo Jin Chung Byoung Kuk Jang Jae Seok Hwang Yong Hoon Kim Jung Hyeok Kwon Mi Sun Choi | 2015 | World Journal of Gastroenterology2015，21，23： | 1 |
| 15 | Should colonoscopy be performed in patients with cryptogenic liver abscess?显示文摘 | Hyun Cheol Koo Young Seok Kim Sang Gyune Kim Jae Woong Tae Bong Min Ko Tae Il Lee Seung Won Jeong Jae Young Jang Hong Soo Kim Sae Hwan Lee Boo Sung Kim | 2012 | Clinics and Research in Hepatology and Gastroenterology2012，，： | 1 |
| 16 | Modeling and Analysis of Lead Frame Structure in Electronic Packaging Using Java and ANSYS显示文摘 | Min Seung Jae Lee Hyoung Seok | 2006 | 2006 (306)2006，，306： | 1 |
| 17 | Transplantation of Autologous Chondrocytes Seeded on a Fibrin/Hyaluronan Composite Gel Into Tracheal Cartilage Defects in Rabbits: Preliminary Results显示文摘 | Hyun Jun Hong Jin Seok Lee Jae Won Choi Byoung‐Hyun Min Han‐Bin Lee Chul‐Ho Kim | 2012 | Artificial Organs2012，，11： | 1 |
| 18 | Properties of Reactive Hot Melt Polyurethane Adhesives with Acrylic Polymer or Macromonomer Modifications显示文摘 | Jin Su Jung Jae Hoon Kim Min Seok Kim | 2008 | J Appl Polym Sci2008，109，： | 1 |
| 19 | Differential Presentations, Clinical Courses, and Survivals of Osteosarcomas of the Proximal Humerus over Other Extremity Locations显示文摘 | Wan Hyeong Cho Won Seok Song Dae-Geun Jeon Chang-Bae Kong Min Suk Kim Jun Ah Lee Ji Young Yoo Jae Do Kim Soo-Yong Lee | 2010 | Annals of Surgical Oncology2010，，3： | 1 |
| 20 | Uncovered self‐expandable metallic stent placement as a first‐line palliative therapy in unresectable malignant duodenal obstruction显示文摘 | Hyung Su Ahn Su Jin Hong Jong Ho Moon Bong Min Ko Hyun Jong Choi Jae Pil Han Jin Seok Park Myung Soo Kang Joo Young Cho Joon Seong Lee Moon Sung Lee | 2012 | Journal of Digestive Diseases2012，，12： | 1 |
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