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| 1 | Successful surgical management of ruptured umbilical hernias in cirrhotic patients显示文摘Acute umbilical hernia rupture in patients with hepatic cirrhosis and ascites is an unusual,but potentially lifethreatening complication,with postoperative morbidity about 70% and mortality between 60%-80% after supportive care and 6%-20% after urgent surgical repair.Management options include primary surgical repair with or without concomitant portal venous system decompression for the control of the ascites.We present a retrospective analysis of our centre's experience over the last 6 years.Our cohort consisted of 11 consecutive patients(median age:53 years,range:36-63 years) with advanced hepatic cirrhosis and refractory ascites.Appropriate patient resuscitation and optimisation with intravenous fluids,prophylactic antibiotics and local measures was instituted.One failed attempt for conservative management was followed by a successful primary repair.In all cases,with one exception,a primary repair with non-absorbable Nylon,interrupted sutures,without mesh,was performed.The perioperative complication rate was 25% and the recurrence rate 8.3%.No mortality was recorded.Median length of hospital stay was 14 d(range:4-31 d).Based on our experience,the management of ruptured umbilical hernias in patients with advanced hepatic cirrhosis and refractory ascites is feasible without the use of transjugular intrahepatic portosystemic shunt routinely in the preoperative period,provided that meticulous patient optimisation is performed. | Nikolaos A Chatzizacharias J Andrew Bradley Simon Harper Andrew Butler Asif Jah Emmanuel Huguet Raaj K Praseedom Michael Allison Paul Gibbs | 2015 | World Journal of Gastroenterology2015，21，10： | 4 |
| 2 | Incidental non-benign gallbladder histopathology after cholecystectomy in an United Kingdom population: Need for routine histological analysis?显示文摘AIM To analyse the range of histopathology detected in the largest published United Kingdom series of cholecystectomy specimens and to evaluate the rational for selective histopathological analysis.METHODS Incidental gallbladder malignancy is rare in the United Kingdom with recent literature supporting selective histological assessment of gallbladders after routine cholecystectomy.All cholecystectomy gallbladder specimens examined by the histopathology department at our hospital during a five year period between March 2008 and March 2013 were retrospectively analysed.Further data was collected on all specimens demonstrating carcinoma,dysplasia and polypoid growths.RESULTS The study included 4027 patients.The majority(97%) of specimens exhibited gallstone or cholecystitis related disease.Polyps were demonstrated in 44(1.09%),the majority of which were cholesterol based(41/44).Dysplasia,ranging from low to multifocal high-grade was demonstrated in 55(1.37%).Incidental primary gallbladder adenocarcinoma was detected in 6 specimens(0.15%,5 female and 1 male),and a single gallbladder revealed carcinoma in situ(0.02%).This large single centre study demonstrated a full range of gallbladder disease from cholecystectomy specimens,including more than 1% neoplastic histology and two cases of macroscopically occult gallbladder malignancies.CONCLUSION Routine histological evaluation of all elective and emergency cholecystectomies is justified in a United Kingdom population as selective analysis has potential to miss potentially curable life threatening pathology. | Krashna Patel Khaled Dajani Satheesh Iype Nikolaos A Chatzizacharias Saranya Vickramarajah Susan Davies Rebecca Brais Siong S Liau Simon Harper Asif Jah Raaj K Praseedom Emmanuel L Huguet | 2016 | World Journal of Gastrointestinal Surgery2016，8，10： | 2 |
| 3 | Clavicular hook plate:complications of retaining the implant显示文摘 | Nadara jah R Mahaluxmivala J Amin A | 2005 | Injury2005，36，： | 1 |
| 4 | Acute Sigmoid Volvulus in a West African Population显示文摘 | Nuhu A Jah A | 2010 | Ann Aft Med2010，9，2： | 1 |
| 5 | Surgical management of hepato-pancreatic metastasis from renal cell carcinoma显示文摘AIM To investigate the outcomes of liver and pancreatic resections for renal cell carcinoma(RCC) metastatic disease. METHODS This is a retrospective, single centre review of liver and/or pancreatic resections for RCC metastases between January 2003 and December 2015. Descriptive statistical analysis and survival analysis using the Kaplan-Meier estimation were performed.RESULTS Thirteen patients h ad 7 pancreatic and 7 liver resections, with median follow-up 33 mo(range: 3-98). Postoperative complications were recorded in 5 cases, with no postoperative mortality. Three patients after hepatic and 5 after pancreatic resection developed recurrent disease. Median overall survival was 94 mo(range: 23-94) after liver and 98 mo(range: 3-98) after pancreatic resection. Disease-free survival was 10 mo(range 3-55) after liver and 28 mo(range 3-53) after pancreatic resection. CONCLUSION Our study shows that despite the high incidence of recurrence, long term survival can be achieved with resection of hepatic and pancreatic RCC metastases in selected cases and should be considered as a management option in patients with oligometastatic disease. | Nikolaos A Chatzizacharias Anais Rosich-Medina Khaled Dajani Simon Harper Emmanuel Huguet Siong S Liau Raaj K Praseedom Asif Jah | 2017 | World Journal of Gastrointestinal Oncology2017，9，2： | 1 |
| 6 | Polyetherketones from Diarylcarboranes: A New Approach to Semi-inorganic Polymers显示文摘 | Colquhoun H M Lewis D F Daniel J A Herbertson P L MacBride JAH Stephenson I R Wade K | 1997 | Polymer1997，38，10： | 1 |
| 7 | Prorenin,rennin angiotensinogen and angiotensin converting enzyme in normal and failing human hearts显示文摘 | Danser JAH Van Kesteren CAM Willem A | 1997 | Circulation1997，96，1： | 1 |
| 8 | Clavicular hook plate: complications of retaining the implant 显示文摘 | Nadara jah R Mahaluxmivala J Amin A | 2005 | Injury2005，36，： | 1 |
| 9 | Detachment of particles during biofilter backwashing显示文摘 | Ahmad R Irthara A M Jah A | 1998 | AWWA1998，90，12： | 1 |
| 10 | Clavicular hook plate:complications of retaining the implant显示文摘 | Nadara jah R Mahaluxmivala J Amin A | 2005 | Injury2005，36，68： | 1 |
| 11 | 垂体催乳素瘤的诊断和治疗指南显示文摘3.男性:高催乳素血症通常导致阳痿、不孕和性功能低下。男性患者通常为大腺瘤,有神经系统症状。其原因可能是对症状认识的延误或者肿瘤生物学行为的差异。 | Casanueva FF Molitch ME Schlechte JA Abs R Bonert V Bronstein MD Brue T Cappabianca Px Cappabianca P Colao A Fahlbusch R Fideleff H Hadani M Kelly P Kleinberg D Laws ED Marek J Scanlon M Sobrinho LG Wass JAH Giustina A 吴哲褒(译) 张亚卓(校) | 2008 | 中华神经外科杂志2008，24，8： | 0 |
| 12 | 垂体催乳素瘤的诊断和治疗指南显示文摘2.药物选择:多巴胺激动剂(dopaminergic agonist,DA),如溴隐亭(bromocfiptine,BRC)和卡麦角林(cabergoline,CAB),为高催乳素血症和PRL腺瘤患者的首选治疗。药物能使绝大多数病人PRL水平正常和肿瘤体积显著缩小,大量的经验证实药物适用于各种大小的肿瘤。所有的DA都是有效的,但pergolide和quinagolide较少使用。患者对一种IDA耐药或者不能耐受,应该换服另一种DA。 | Casanueva FF Molitch ME Schlechte JA Abs R Bonert V Bronstein MD Brue T Cappabianca P Colao A Fahlbusch R Fideleff H Hadani M Kelly P Kleinberg D Laws ED Marek J Scanlon M Sobrinho LG Wass JAH Giustina A 吴哲褒(译) 张亚卓(校) | 2008 | 中华神经外科杂志2008，24，11： | 0 |
| 13 | 垂体催乳素瘤的诊断和治疗指南显示文摘2005年6月,在SanDiego举行了第九届国际垂体研究大会。大会邀请在催乳素瘤治疗领域被认可的国际知名专家,包括内分泌专家和神经外科专家,特定召开专业委员会,对催乳素瘤的诊断和治疗进行探讨,并形成该指南。指南发表在2006年8月的临床内分泌学杂志上(Clinical Endocrinology,2006,65:265—273)。 | Casanueva FF Molitch ME Schlechte JA Abs R Bonert V Bronstein MD Brue T Cappabianca P Colao A Fahlbusch R Fideleff H Hadani M Kelly P Kleinberg D Laws ED Marek J Scanlon M Sobrinho LG Wass JAH Giustina A 吴哲褒(译) 张亚卓(校) | 2008 | 中华神经外科杂志2008，24，6： | 0 |
| 14 | Colonic and anal metastases from pancreato-biliary malignancies显示文摘Pancreato-biliary malignancies often present with locally advanced or metastatic disease.Surgery is the mainstay of treatment although less than 20%of tumours are suitable for resection at presentation.Common sites for metastases are liver,lungs,lymph nodes and peritoneal cavity.Metastatic disease carries poor prognosis,with median survival of less than 3 mo.We report two cases where metastases from pancreato-biliary cancers were identified in the colon and anal canal.In both cases specific immunohistochemical staining was utilised in the diagnosis.In the first case,the pre-senting complaint was obstructive jaundice due to an ampullary tumour for which a pancreato-duodenectomy was carried out.However,the patient re-presented 4wk later with an atypical anal fissure which was found to be metastatic deposit from the primary ampullary adenocarcinoma.In the second case,the patient presented with obstructive jaundice due to a biliary stricture.Subsequent imaging revealed sigmoid thickening,which was confirmed to be a metastatic deposit.Distal colonic and anorectal metastases from pancreatobiliary cancers are rare and can masquerade as primary colorectal tumours.The key to the diagnosis is the specific immunohistochemical profile of the intestinal lesion biopsies. | Farshid Ejtehadi Nikolaos A Chatzizacharias Rebecca J Brais Nigel R Hall Edmund M Godfrey Emmanuel Huguet Raaj K Praseedom Asif Jah | 2014 | World Journal of Gastroenterology2014，20，13： | 0 |
| 15 | 垂体催乳素瘤的诊断和治疗指南显示文摘首次测定确立高催乳素血症必需避免过度的静脉穿刺压力,理想的情况是醒后或饭后至少1h来测试。单一的PRL测量对诊断来说通常是足够的。当首次的PRL值不具有诊断价值(比如高于正常值范围,但没有足够高到明确提示PRL腺瘤的水平),应改天再测。对于这一情况,为避免脉冲式分泌的影响,2~3个标本之间必需间隔15—20min。女性患者怀孕不总是伴有高催乳素血症,因此在诊断评价之前行妊娠试验以排外妊娠相关的高催乳素血症。 | Casanueva FF Molitch ME Schlechte JA Abs R Bonert V Bronstein MD Brue T Cappabianca P Colao A Fahlbusch R Fideleff H Hadani M Kelly P Kleinberg D Laws ED Marek J Scanlon M Sobrinho LG Wass JAH Giustina A 吴哲褒(译) 张亚卓(校) | 2008 | 中华神经外科杂志2008，24，10： | 0 |
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