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| 1 | Novel insights on the structural determinants of clozapine and olanzapine multi-target binding profiles显示文摘 | Jana S Maria MS Javier R | 2014 | Eur J Med Chem2014，77，13： | 1 |
| 2 | Inhibition of Rho kina- ses increases directional motility of microvascular endotheli- al cells 显示文摘 | Johannes B Jana S Margot R | 2012 | Biochemical Pharmacology2012，83，5： | 1 |
| 3 | Fluorescent Carbon Nanoparticles: Synthesis, Characterization,and BioimagingApplication 显示文摘 | RAY S C SAHA A JANA N R | 2009 | Journal of Physical Chemistry C2009，113，18： | 1 |
| 4 | Fluorescent carbon nano- particles:Synthesis, characterization, and bioimaging appli cation显示文摘 | Ray S C Saha A Jana N R | 2009 | J Phys Chem C2009，113，18： | 1 |
| 5 | Fluorescent carbon nanoparti- cles: Synthesis, characterization, and bioimaging application显示文摘 | Ray S C Saha A Jana N R | 2009 | J Phys Chem C2009，113，18： | 1 |
| 6 | Langmuir-Btodgett thin films of quantum dots : synthesis, surface modification and fluorescence resonance energy transfer (FRET) studies 显示文摘 | Gole A Jana N R Selvan S T | 2008 | Langmuir2008，24，15： | 1 |
| 7 | Protection of mice against lethal viral infection by synthetic peptides corresponding to B-and T-cell recognibon sites of immuenza A hemagglutinin显示文摘 | Jana S R Zhong Yun Philip R | 1995 | Vaccine1995，13，： | 1 |
| 8 | Multiplexed Biosensing Diagnostic Platforms Detecting Autoantibodies to Tumor-Associated Antigens from Exosomes Released by CRC Cells and Tissue Samples Showed High Diagnostic Ability for Colorectal Cancer显示文摘Colorectal cancer(CRC)is the second leading cause of cancer-related death worldwide.The five-year survival rate of CRC patients depends on the stage at diagnosis,being higher than 80%when CRC is diagnosed in the early stages but lower than 10%when CRC is diagnosed in advanced stages.Autoantibodies against specific CRC autoantigens(tumor-associated antigens(TAAs))in the sera of patients have been widely demonstrated to aid in early diagnosis.Thus,we herein aim to identify autoantigens target of autoantibodies specific to CRC that possess a significant ability to discriminate between CRC patients and healthy individuals by means of liquid biopsy.To that end,we examined the protein content of the exosomes released by five CRC cell lines and tissue samples from CRC patients by means of immunoprecipitation coupled with mass spectrometry analysis.A total of 103 proteins were identified as potential autoantigens specific to CRC.After bioinformatics and meta-analysis,we selected 15 proteins that are more likely to be actual CRC autoantigens in order to evaluate their role in CRC prognosis by Western blot(WB)and immunohistochemistry(IHC).We found dysregulation at the protein level for 11 of these proteins in both tissue and plasma exosome samples from patients,along with an association of nine of these proteins with CRC prognosis.After validation,all but one showed a statistically significant high diagnostic ability to distinguish CRC patients and individuals with premalignant lesions from healthy individuals,either by luminescence Halotag-based beads,or by a multiplexed biosensing platform involving the use of magnetic microcarriers as solid support modified with covalently immobilized Halotag fusion proteins constructed for CRC detection.Taken together,our results highlight the usefulness of the approach defined here to identify the TAAs specific to chronic diseases;they also demonstrate that the measurement of autoantibody levels in plasma against the TAAs identified here could be integrated into a point-of-care(POC)device for CRC detection with high diagnostic ability. | Ana Montero-Calle Itziar Aranguren-Abeigon María Garranzo-Asensio Carmen Poves María Jesús Fernández-Aceñero Javier Martínez-Useros Rodrigo Sanz Jana Dziaková Javier Rodriguez-Cobos Guillermo Solís-Fernández Eloy Povedano Maria Gamella Rebeca Magnolia Torrente-Rodríguez Miren Alonso-Navarro Vivian de los Ríos J.Ignacio Casal Gemma Domínguez Ana Guzman-Aranguez Alberto Peláez-García JoséManuel Pingarrón Susana Campuzano Rodrigo Barderas | 2021 | Engineering2021，7，10： | 1 |
| 9 | An efficient and green synthesis of 2-arylbenzothiazoles in an ionic liquid, Br under microwave irradiation 显示文摘 | RANU B C JANA R DEY S | 2004 | Chem Lett2004，33，3： | 1 |
| 10 | Measurement and modeling of an ultra-wide bandwidth indoor channel显示文摘 | Ghassemzadeh S S Jana R Rice C | 2004 | IEEE Transactions on Communications2004，52，： | 1 |
| 11 | Novel floating ideal tunable FDNR simulation using current conveyors显示文摘 | NANDI S JANA P B NANDI R | 1984 | IEEE Trans on CAS1984，31，4： | 1 |
| 12 | ZSM-5 and H-J3 zeolites and Fe203 or FeC13 deposited on micro-, meso-and macro-porous supports显示文摘 | Choudhary V R Jana S K Mamman A S | 2002 | Microporous and Mesoporous Materials2002，56，1： | 1 |
| 13 | Purification and characterization of xylanase from ahyperxylanolytic mutant ofAspergillus ochraceus显示文摘 | BISWAS S R JANA S C MISHRA A K | 1990 | Biotechnol Bioeng1990，，35： | 1 |
| 14 | Sustained activation of mitogen-activated protein kinases and activator protein 1 by the hepatitis B virus X protein in mouse hepatocytes in vivo显示文摘 | Njhara R Jana S S Goswami S K | 2001 | J Virol2001，75，10： | 1 |
| 15 | Highly active and moisture-insensitive solid catalysts-GaCl3 and InCl3 supported on montmorillonite-K10 and Si-MCM-41 for benzylation of benzene 显示文摘 | CHOUDHAY V R JANA S K KIRAN B P | 2000 | Catalysis Letters2000，192，24： | 1 |
| 16 | Alkylation of benzene by benzyl chloride over H-ZSM-5 zeolite with its framework Al completely or partially substituted by Fe or Ga显示文摘 | Choudhary V R Jana S K Kiran B P | 1999 | Catalysis Letters1999，59，24： | 1 |
| 17 | 查看详情显示文摘 | Ray S Saha A Jana N.R Sarkar R | | 0，，： | 1 |
| 18 | Intralaminar frac-ture toughness of a cross-ply laminate and its constituentsub-laminates 显示文摘 | Jose S Ramesh K R Jana M K | 2001 | Composites Science and Technology2001，61，8： | 1 |
| 19 | Acyla- tion of aromatic compounds using moisture insensitive InC13 impregnated mesoporous Si-MCM-41 catalyst显示文摘 | Vasant R Choudhary Suman K Jana Nilesh S Patil | 2002 | Tetrahed- ron Letters2002，43，： | 1 |
| 20 | Fluorescent carbon nanoparticles: Synthesis, characterization, and bioimaging application显示文摘 | RAY S C SAHA A JANA N R | 2009 | The Journal of Physical Chemistry C2009，113，18： | 1 |
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