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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | Insulin resistance is associated with chronic hepatitis C and virus infection fibrosis progression显示文摘 | Jason M Hui Archana Sud Geoffrey C Farrell Priyanka Bandara Karen Byth James G Kench Geoffrey W McCaughan Jacob George | 2003 | Gastroenterology2003，，6： | 2 |
| 3 | Extraction and quan- tification of daidzein and genistein in food 显示文摘 | Jason L Ieslie J C Bluek W I | 1998 | Ana- lytical Biochemistiy1998，264，1： | 1 |
| 4 | Recent advance in techniques for hyperspectral image processing显示文摘 | Antonio P Jon A B Joseph W B Jason B Lorenzo B Gustavo C V Jocelyn C Mathieu F Paolo G Anthony G Mattia M James C T Giovanna T | 2009 | Remote Sensing of Environment2009，113，： | 1 |
| 5 | Shrimp aquaculture and the environment 显示文摘 | Boyd C E Jason W C | 1998 | Sci Am1998，278，6： | 1 |
| 6 | Circulat- ing and dietary magnesium and risk of cardiovascular disease:A systematic review and meta-analysis of pro- spective studies 显示文摘 | Liana C D G Fumiaki I Jason H Y W | 2013 | Am J Clin Nutr2013，98，1： | 1 |
| 7 | Selective determination of amino acids using flow injection analysis coupled with chemiluminescence detection 显示文摘 | JASON W C PAUL S F SIMON W L | 2003 | Anal Chim Acta2003，480，： | 1 |
| 8 | Formation and control of box-shaped ultra-shallow junction using laser annealing and pre-amorphization implantation显示文摘 | Kim S D Park C M Jason C S W | 2005 | Solid-State Electronics2005，49，1： | 1 |
| 9 | Automated interpolation of two-dimensional seismic grids into three-dimensional data volume显示文摘 | Jason ChinSen Kao J C Schneider W A | 1990 | Geophysics1990，55，4： | 1 |
| 10 | Evaluation of radiation dose and positioning accuracy on X-ray volume imaging system for image-guided radiotherapy显示文摘 | Jason C Chia L Jian W | 2008 | Nucl Instrum Meth Phys Res2008，266，： | 1 |
| 11 | The effect of vitamin E on blood pressure in individuals with type 2 diabetes: a randomized, double-blind, placebo-controlled trial显示文摘 | Natalie C Ward Jason HY Wu Michael W Clarke Ian B Puddey Valerie Burke Kevin D Croft Jonathan M Hodgson | 2007 | Journal of Hypertension2007，，1： | 1 |
| 12 | 查看详情显示文摘 | Leila H Jason W H Danni C | | 0，，1： | 1 |
| 13 | Devel- opment and application of a muhimodal contrast ggent for SPECT/CT hybrid imaging 显示文摘 | Jason M C Lawrence W D Zhen W Z etal | 2011 | Bioconjug Chem2011，22，： | 1 |
| 14 | The tun- nel source(PNPN) n-MOSFET: A novelHigh per- formance transistor显示文摘 | N Venkatagirish J Ritesh C S W Jason | 2008 | IEEE Transations on Electr on Devices2008，55，4： | 1 |
| 15 | Differential bioavailability of field weathered p,p-DDE to plants of the Cucurbita and Cucumis genera显示文摘 | Jason C W | 2002 | Chemosphere2002，49，2： | 1 |
| 16 | Spermine compaction is an efficient and economical method of producting vaccine-grande DNA显示文摘 | Dan V Mourich Michael W Munks Jason C Murphy | 2003 | Journal of Immunological Methods2003，27，： | 1 |
| 17 | X-Ray Absorp-tion Fine Structure Characterization of the Local Structure ofFe in Fe-ZSM-5 显示文摘 | Sun H C Benjamin R W Jason A R | 2003 | J Phys Chem B2003，107，11： | 1 |
| 18 | Extraction and q uantification of daidzein and genistein in food显示文摘 | Jason Liggins Leslie J C Bluck W | 1998 | Analytical Biochemistry1998，264，： | 1 |
| 19 | Late Quaternary slip rate gradient defined using high-resolution topography and Be dating of offset landforms on the southern San Jacinto Fault zone, California 显示文摘 | Blisniuk K Rockwell T Owen L A Oskin M Lippincott C Caffee M W Dortch Jason | 2010 | Journal of Geophysical Research2010，11，508： | 1 |
| 20 | Treatment and outcomes of primary breast lymphoma显示文摘 | Julianna C Elaine S W Jason H | 2012 | Clinical Breast Cancer2012，12，6： | 1 |
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