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| 1 | 14-day triple, 5-day concomitant, and 10-day sequential therapies for Helicobacter pylori infection in seven Latin American sites: a randomised trial显示文摘 | E Robert Greenberg Garnet L Anderson Douglas R Morgan Javier Torres William D Chey Luis Eduardo Bravo Ricardo L Dominguez Catterina Ferreccio Rolando Herrero Eduardo C Lazcano-Ponce María Mercedes Meza-Montenegro Rodolfo Pe?a Edgar M Pe?a Eduardo Salazar- | 2011 | The Lancet2011，，9790： | 2 |
| 2 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 3 | Diabetes mellitus, revascularization and outcomes in elderly patients with myocardial infarction-related cardiogenic shock显示文摘Background The prognostic role of diabetes mellitus(DM)in elderly patients with myocardial infarction-related cardiogenic shock(MI-CS)remains controversial.Little information exists about the impact of intensive cardiac care unit(ICCU)and revascularization on outcomes of elderly patients with MI-CS.We aimed to assess the prognostic impact of DM according to age in patients with MI-CS,and to analyze the impact ICCU management and revascularization on in-hospital mortality in MI-CS patients at older ages.Methods Discharge episodes with diagnosis of CS associated with MI were selected from the Spanish National Health System’s Basic Data Set.Centers were classified according to their availability of ICCU.Main outcome measured was in-hospital mortality.Results A total of 23,590 episodes of MI-CS were identified,of whom 12,447(52.8%)were in patients aged≥75 years.The impact of DM on in-hospital mortality was different among age subgroups.While in younger patients,DM was associated to a higher mortality risk(0.52 vs.0.47,OR=1.12,95%CI:1.06–1.18,χ^2<0.001),this association became non-significant in older patients(0.76 vs.0.81,χ^2=0.09).Adjusted mortality rate of MI-CS aged≥75 years was lower in patients admitted to hospitals with ICCU(adjusted mortality rate:74.2%vs.77.7%,P<0.001)and in patients undergoing revascularization(74.9%vs.77.3%,P<0.001).Conclusions Prognostic impact of DM in patients with MI-CS was different according to age,with a significantly lower impact at older ages.The availability of ICCU and revascularization were associated with better outcomes in these complex patients. | Miquel Gual Albert Ariza-Solé María García Márquez Cristina Fernández JoséL Bernal Francesc Formiga María-Isabel Barrionuevo JoséC Sánchez-Salado Victòria Lorente Júlia Pascual Isaac Llaó Oriol Alegre Angel Cequier Javier Elola | 2020 | Journal of Geriatric Cardiology2020，17，10： | 2 |
| 4 | Randomized trial of permisive hypercapnia in preterm infants显示文摘 | Gonzalo M Javier C Moldemar AC | 1999 | Pediatrics1999，104，： | 1 |
| 5 | Cloning, expression, and characterization ofavian reovirus guanylytransferase显示文摘 | Joseph H Jose M C Javier B | 2002 | Virology2002，296，2： | 1 |
| 6 | Perceived value of the purchase of a tourism product显示文摘 | Javier S Luis C Rosa M | | 0，，： | 1 |
| 7 | Comparison of double-pulse and single-pulse laser-induced breakdown spectroscopy techniques in the analysis of powdered samples of silicate raw materials for the brick-and-tile industry 显示文摘 | Tereza C Luisa M C Javier L | 2008 | Spectrochimica Acta Part B2008，63，1： | 1 |
| 8 | Review of strain rate effects for concrete in tension显示文摘 | Javier M L Ross C A | 1998 | ACI Material Journal1998，95，6： | 1 |
| 9 | Promoting cardiovascularhealth worldwide: strategies, challenges, and opportunities显示文摘 | JOSE M C JAGAT N JAVIER C | 2014 | Revista Espafiola de Cardiologia:English edition2014，67，9： | 1 |
| 10 | Changes in the expression of melatonin receptors induced by melatonin treatment in hepatocarcinoma HepG2 cells显示文摘 | Sara C P Javier M R Andres G P | 2009 | J Pineal Res2009，47，2： | 1 |
| 11 | Antioxidant and metal chelating activities of peptide fractions from phaseolin and bean protein hydrolysates显示文摘 | JANET C ALAN JAVIER H CRISTIAN J M | | 0，，03： | 1 |
| 12 | Spectroscopic study of oxygen adsorption on CeO2/γ-Al2O3 catalysts显示文摘 | Juan M C José C C | 1996 | J Chem Soc Faraday Trans1996，92，9： | 1 |
| 13 | Transistor paint:high mobilities in small bandgap polymer semiconductor based on the strong acceptor,diketopyrrolopyrrole and strong donor,dithienopyrrole显示文摘 | Toby L N Tomasz M Y Jun Y L Mishra S P Belot J A Balliet C L Javier A E Kowalewski T McCullough R D | 2010 | Advanced Materials2010，22，41： | 1 |
| 14 | FPGA implementation of an OFDM-based WLAN receiver 显示文摘 | MARIA J C JAVIER V VICENC A JOSE M R | 2012 | Microprocessors and Microsystems2012，36，3： | 1 |
| 15 | A new approach to pruning Volterra models for power amplifiers 显示文摘 | CARLOS C C JAVIER R T MARIA J M A JEsus M C | 2010 | IEEE Transactions on Signal Processing2010，58，4： | 1 |
| 16 | Sistemas transcurrentes de escala litosferica en el Sur del Peru显示文摘 | Thierry S Javier J Victor C William M Conrado B Michel F Pierrick R Harmuth A Jorge A Luis C Alexander F Ivanoff I Omar L Mirian M Paola M Francis O Yovani O Adan P and Rildo R | | 0，，05： | 1 |
| 17 | Robust support vector method for hyperspectral data classification and knowledge discovery显示文摘 | Custavo C V Luis G C Javier C M | 2004 | IEEE Transactions on Geoscience and Remote Sensing2004，42，7： | 1 |
| 18 | Power Systems Decentralized Optimization显示文摘 | Ramirez Juan M Javier C G | 2014 | International Journal of Emerging Electric Power Systems2014，15，6： | 1 |
| 19 | Hydroisomerization-cracking of n-octane on heteropolyacid HaPW12040 supported on ZrO2, SiO2 and carbon: Effect of Pt incorporation on catalyst performance显示文摘 | Juan C Yori Javier M Grau Viviana M Benltez | 2005 | Applied Catalysis A:General2005，286，1： | 1 |
| 20 | Lactulose bienzyme biosensor based on self-assembled monolayer modified electrodes 显示文摘 | Susana C Pedrero M Javier M | 2004 | Electroanalysis2004，17，： | 1 |
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