7篇
您的检索式：作者名="Jesse Roman"
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| 1 | Anticancer actions of PPARγ ligands:Current state and future perspectives in human lung cancer显示文摘Peroxisome proliferator-activated receptors(PPARs) are ligand-dependent nuclear transcription factors and members of the nuclear receptor superfamily.Of the three PPARs identified to date(PPARγ,PPARβ/δ,and PPARα),PPARγ has been studied the most,in part because of the availability of PPARγagonists(also known as PPARγ ligands)and its significant effects on the management of several human diseases including type 2 diabetes,metabolic syndrome,cardiovascular disease and cancers.PPARγ is expressed in many tumors including lung cancer,and its function has been linked to the process of lung cancer development, progression and metastasis.Studies performed in gynogenic and xenograft models of lung cancer showed decreased tumor growth and metastasis in animals treated with PPARγ ligands.Furthermore,data are emerging from retrospective clinical studies that suggest a protective role for PPARγ ligands on the incidence of lung cancer.This review summarizes the research being conducted in this area and focuses on the mechanisms and potential therapeutic effects of PPARγ ligands as a novel anti-lung cancer treatment strategy. | Jesse Roman | 2010 | World Journal of Biological Chemistry2010，1，3： | 3 |
| 2 | Targeted Deletion of Metalloproteinase 9 Attenuates Experimental Colitis in Mice: Central Role of Epithelial-Derived MMP显示文摘 | Florencia E. Castaneda Baljit Walia Matam Vijay–Kumar Neal R. Patel Susanne Roser Vasantha L. Kolachala Mauricio Rojas Lixin Wang Gabriela Oprea Pallavi Garg Andrew T. Gewirtz Jesse Roman Didier Merlin Shanthi V. Sitaraman | 2005 | Gastroenterology2005，，6： | 1 |
| 3 | Thiazolidinediones as anti-cancer agents显示文摘 | Carmelo Blanquicett Jesse Roman Michael Hart C | 2008 | Cancer Ther2008，，： | 1 |
| 4 | Rosigtitazone suppresses human lung car - cinoma cell growth through PPAR - dependent and PPAR - independent signal pathways 显示文摘 | Hart S W Jesse Roman | 2006 | Mol Cancer Ther2006，5，： | 1 |
| 5 | Technical Challenges of Total Esophageal Reconstruction Using A Supercharged Jejunal Flap显示文摘 | Melissa Poh Jesse C. Selber Roman Skoracki Garrett L. Walsh Peirong Yu | 2011 | Annals of Surgery2011，，6： | 1 |
| 6 | Moving away from PPARs - EGFR signaling and the anti cancer effects of thiazolinedinediones显示文摘 | Jesse Roman | 2009 | Cell Research2009，19，6： | 0 |
| 7 | Tumor Cell-stromal Interactions in Lung Cancer显示文摘It is well known that tumors establish themselves and progress within a tissue microenvironment that includes host stromal cells and extracellular matrices. However, the impact that the composition of the | Jesse ROMAN, MD Shouwei HAN, MD, PhD | 2009 | 中国肺癌杂志2009，12，6： | 0 |
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