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| 1 | Synergistic anticancer effect of green synthesized nickel nanoparticles and quercetin extracted from Ocimum sanctum leaf extract显示文摘Leaf extract of medicinally important plant Ocimum sanctum(O. sanctum) has been used for the synthesis of nickel nanoparticles(Ni Gs) and extraction of quercetin(Qu). Qu has been conjugated with Ni Gs for enhanced anticancer effect on human breast cancer MCF–7 cells. Extracted Qu was conjugated with polyethylene glycol(PEG) coated Ni Gs(Qu–PEG–Ni Gs) which was used as carriers for breast cancer treatment. Anticancer activity of Qu–PEG–Ni Gs was evaluated by assessing cell viability, reactive oxygen species(ROS) production, caspase activity, mitochondrial membrane potential(MMP) and changes in nuclear morphology(staining methods). 0.85 mg of quercetin was extracted from 1 g of leaves with retention time(R_t) of 2.914 min. Loading and encapsulation efficiency of quercetin onto PEG–Ni Gs was 15.04% and 82% respectively and Qu–PEG–Ni Gs has shown a sustained release of Qu of about 84% after 48 h. Qu and Qu–PEG–Ni Gs showed dose dependent(1.56–50 μg/m L) anticancer effect against MCF–7 cells with IC50 values of 50 and 6.25 μg/m L respectively which was mediated by oxidative stress due to ROS over-production that induced loss of mitochondrial membrane potential, capsase-9,-7 activities leading to apoptosis. The present study validates that Qu–PEG–Ni Gs can be used as a potential anticancer agent for cancer therapy. | Palanivel Rameshthangam Jeyaraj Pandian Chitra | 2018 | Journal of Materials Science & Technology2018，34，3： | 5 |
| 2 | Phytochemical analysis and in vitro antimicrobial activity of Illicium griffithii Hook. f. & Thoms extracts显示文摘 | A Vijayakumar V Duraipandiyan B Jeyaraj P Agastian M Karunai Raj S Ignacimuthu | 2012 | Asian Pacific Journal of Tropical Disease2012，，3： | 4 |
| 3 | Mechanical Properties of Natural Fiber Braided Yarn Woven Composite: Comparison with Conventional Yarn Woven Composite显示文摘增强在编织的纱形式的自然纤维的效果聚合物的机械性质上的编织织物合成被调查。编织的纱织物 composites 的结果与常规纱织物相比为纤维重量的一样的百分比的合成、随机的面向的亲密地混合的短纤维 composites。intra 厚度杂交的效果由沿着一件编织织物的二个不同方向把二不同自然纤维作为纱,在编织织物的机械性质上合成也被分析。自然纤维编织的纱织物加强显著地与常规编织织物和短纤维加强的相比增加了 composites 的机械性质。二不同自然纤维的 Intra 厚度杂交改进了常规编织织物的机械性质合成当它不能提高编织织物的性质时合成。在影响性质的改进由于编织的纱织物加强与张力、曲折的性质相比很高。 | Murugan Rajesh Jeyaraj Pitchaimani | 2017 | Journal of Bionic Engineering2017，14，1： | 2 |
| 4 | Biosynthesis, purification and characterization of silver nanoparticles using Escherichia coli显示文摘 | Sangiliyandi Gurunathan Kalimuthu Kalishwaralal Ramanathan Vaidyanathan Deepak Venkataraman Sureshbabu Ram Kumar Pandian Jeyaraj Muniyandi Nellaiah Hariharan Soo Hyun Eom | 2009 | Colloids and Surfaces B: Biointerfaces2009，，1： | 2 |
| 5 | Vibration and acoustic response of a composite plate with inherent material damping in a thermal environment显示文摘 | Jeyaraj P Ganesan N | 2009 | Journal of Sound and Vi- bration2009，320，12： | 1 |
| 6 | SRS06,a new semi- synthetic andrographolide derivative with improved anticancer potency and selectivity,inhibits nuclear factor -kB nuclear bind ing in the A549 non-small cell lung cancer cell line显示文摘 | Lim J C Jeyaraj E J Sagineedu S R | 2015 | Phar macology2015，95，12： | 1 |
| 7 | Thermal Degradation Kinetics of Structurally Diverse Poly(bispropargyl ethers-bismaleimide) Blends显示文摘Structurally diverse bispropargyl ethers using resorcinol,quinol,4,4￠-dihydroxy biphenyl,bisphenol-A,4,4￠-dihydroxy diphenyl ketone,4,4￠-dihydroxy diphenylsulphone,trimethyl indane bisphenol and tetramethyl spirobiindane bisphenol were prepared by using phase transfer catalyst.Synthesized materials were separately blended with 4,4￠-bismaleimido diphenyl methane(BMIM)in mole ratios(0.5:0.5).The materials were thermally cured and the structural characterisation and the thermal properties of these cross-linked materials are investigated using Fourier-transform infrared(FTIR)spectrophotometer and thermogravimetric analyzer(TGA).Among the different materials investigated poly MRPE,poly MBPEBPA and poly MSPE show higher onset degradation temperature of 300°C indicating higher thermal stability.The degradation kinetics is investigated using Flynn-Wall-Ozawa(FWO),Vyazovkin(VYZ)and Friedman(FRD)methods.Amongst the various cured materials investigated,the activation energy(Ea-D)values obtained for poly MRPE and poly MKPE were observed to increase continuously froma=0.2 to 0.8 and the values range from 199 kJ/mol to 245 k J/mol and 153 k J/mol to 295 k J/mol respectively.The crosslinked materials resulting from these bispropargyl monomers definitely need more energy for bond cleavage due to the presence of more aromatic units.The volatile products obtained during the thermal degradation of the polymers were analyzed using thermogravimetric-Fourier transform infrared analyses(TG-FTIR).The phenols,substituted phenols,carbon monoxide,carbon dioxide and small amount of aniline were found to be the major products during thermal degradation of these cured blends. | Jeyaraj Pandiyan Dhanalakshmi Mahendran Arunjunai Raj Chinnaswamy Thangavel Vijayakumar | 2016 | Chinese Journal of Polymer Science2016，34，3： | 1 |
| 8 | Evidence that intravenous vasopressors can affect rostral spread of spinal anesthesia in pregnancy显示文摘 | Cooper D W Jeyaraj L Hynd R | 2004 | Anesthesiology2004，101，1： | 1 |
| 9 | Circadian rhythms govern cardiac repolarization and arrhythmogenesis 显示文摘 | Jeyaraj D Haldar S M Wan X | 2012 | Nature2012，483，7387： | 1 |
| 10 | Humidity-sensing properties of ZnCr2O4-ZnO composites显示文摘 | POKHREL S JEYARAJ B NAGARAJA K S | 2003 | Mater Lett2003，57，10： | 1 |
| 11 | Cardiac electrical remodeling in health and disease 显示文摘 | Cutler MJ Jeyaraj D Rosenbaum DS | 2011 | Trends Pharmacol Sci2011，32，3： | 1 |
| 12 | Short-term load forecasting using time series methods显示文摘 | Jeyaraj K Paranothi S R | 1994 | Journal of the Institution of Engineers Electrical Engineering Division1994，，8： | 1 |
| 13 | Vibration and acoustic response of an isotropic plate in a thermal environment显示文摘 | Jeyaraj P Padmanabhan C Ganesan N | | 0，，10： | 1 |
| 14 | Study on durability of high performance concrete with industrial wastes显示文摘 | Pazhani K Jeyaraj R | 2011 | Applied Technologies & Innovations2011，2，2： | 1 |
| 15 | Effects of long-term administration of androgens and estrogen on rhesus monkey prostate: possible induction of benign prostatic hyperplasia 显示文摘 | Jeyaraj DA Udayakumar TS Rajalakshmi M Pal PC Sharma RS | 2000 | J Androl2000，21，6： | 1 |
| 16 | Passive smoking and breast cancer-a suspicious link显示文摘 | Malik A Jeyaraj PA Shankar A | 2015 | Asian Pac J Cancer Prev2015，16，14： | 1 |
| 17 | An unusual case of isolated, serial metasta- ses of gallbladder carcinoma involving the chest wall, axilla, breast and lung parenchyma显示文摘 | Jeyaraj P Sio TT Iott MJ | 2013 | Rare Tumors2013，5，1： | 1 |
| 18 | Kruppel-like factor 15 regulates skeletal muscle lipid flux and exercise adaptation显示文摘 | Haldar S M Jeyaraj D Anand P | 2012 | Proc Natl Acad Sci U S A2012，109，17： | 1 |
| 19 | Klf15 orchestrates circadian nitrogen homeostasis显示文摘 | Jeyaraj D Scheer F A Ripperger J A | 2012 | Cell Metab2012，15，3： | 1 |
| 20 | A review of the pre- dictors, linkages and biases in IT innovation adoption re- search显示文摘 | Jeyaraj A Rottman J W Lacity M C | 2006 | Information Technology2006，21，1： | 1 |
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