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您的检索式：作者名="Jiao Zhenming"
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| 1 | A comparative study of Ni/Al_2O_3–SiC foam catalysts and powder catalysts for the liquid-phase hydrogenation of benzaldehyde显示文摘In this study, Al_2O_3-washcoated SiC(Al_2O_3–SiC) foams and Al_2O_3 powder were employed as the supports of a Ni catalyst for the liquid-phase hydrogenation of benzaldehyde. A series of Ni/Al_2O_3–SiC foam catalysts and Ni/Al_2O_3 powder catalysts with a Ni loading from 10 wt% to 37 wt% of the weight of Al_2O_3 were first prepared by a deposition–precipitation(DP) method. The catalytic activity and recyclability of both kinds of catalysts were then compared. Although it had a smaller accessible surface area with the reactant, the foam catalyst with a Ni loading of 16 wt% exhibited a slightly higher conversion of benzaldehyde after 6 h(of 99.3%) in comparison with the Ni/Al_2O_3 catalyst with identical Ni loading(conversion of 97.5%). When the Ni loading increased from 16 wt% to 37 wt%, the reaction rate obtained with the foam catalyst increased significantly from 0.108 to 0.204 mol L^(-1)h^(-1), whereas the reaction rate obtained with the powder catalyst increased from 0.106 to 0.123 mol L^(-1)h^(-1). Furthermore, the specific activity(moles of benzaldehyde consumed by 1 g min^(-1)of Ni) of the foam catalyst with a Ni loading above 30 wt% was superior to that of the powder catalyst because of its smaller Ni-particle size and higher mass-transfer rate. The foam catalyst displayed a high recyclability as a function of run times owing to the strong interaction between the Ni component and the Al_2O_3 coating. The conversion of benzaldehyde over the foam catalyst remained almost unchanged after being used 8 times. In comparison, a drop of 43% in the conversion of benzaldehyde with the powder catalyst was observed after being used 7 times due to the leaching of the Ni component. | Kai Li Yilai Jiao Zhenming Yang Jinsong Zhang | 2019 | Journal of Materials Science & Technology2019，35，1： | 2 |
| 2 | Group partition and systems of orthogonal idempotents显示文摘 | Zhang Yingshan Pang Shanqi Jiao Zhenming | 1998 | Linear Algebra and its Application1998，278，： | 1 |
| 3 | Controllable synthesis of ZSM-5 coatings on SiC foam support for MTP application显示文摘 | Jiao Yilai Jiang Chunhai Yang Zhenming | 2012 | Microporous Mesoporous Mater2012，162，： | 1 |
| 4 | Controllable Synthesis of ZSM-5 Coatings on Si C Foam Support for MTP Application显示文摘 | Jiao Yilai Jiang Chunhai Yang Zhenming | 2012 | Microporous Mesoporous Mater2012，162，： | 1 |
| 5 | Carbazole and tetrahydro-carboline derivatives as dopamine D_(3) receptor antagonists with the multiple antipsychotic-like properties显示文摘Dopamine D_(3) receptor(D_(3)R)is implicated in multiple psychotic symptoms.Increasing the D_(3)R selectivity over dopamine D_2 receptor(D_2R)would facilitate the antipsychotic treatments.Herein,novel carbazole and tetrahydro-carboline derivatives were reported as D_(3)R selective ligands.Through a structure-based virtual screen,ZLG-25(D_(3)R K_i=685 nmol/L;D_2R K_i>10,000 nmol/L)was identified as a novel D_(3)R selective bitopic ligand with a carbazole scaffold.Scaffolds hopping led to the discovery of novel D_(3)R-selective analogs with tetrahydro-β-carboline or tetrahydro-γ-carboline core.Further functional studies showed that most derivatives acted as h D_(3)R-selective antagonists.Several lead compounds could dose-dependently inhibit the MK-801-induced hyperactivity.Additional investigation revealed that 23j and 36b could decrease the apomorphine-induced climbing without cataleptic reaction.Furthermore,36b demonstrated unusual antidepressant-like activity in the forced swimming tests and the tail suspension tests,and alleviated the MK-801-induced disruption of novel object recognition in mice.Additionally,preliminary studies confirmed the favorable PK/PD profiles,no weight gain and limited serum prolactin levels in mice.These results revealed that 36b provided potential opportunities to new antipsychotic drugs with the multiple antipsychotic-like properties. | Zhongtang Li Fan Fang Yiyan Li Xuehui Lv Ruqiu Zheng Peili Jiao Yuxi Wang Guiwang Zhu Zefang Jin Xiangqing Xu Yinli Qiu Guisen Zhang Zhongjun Li Zhenming Liu Liangren Zhang | 2023 | Acta Pharmaceutica Sinica B2023，13，11： | 0 |
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