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| 1 | Ideal cardiovascular health and incidence of atherosclerotic cardiovascular disease among Chinese adults:the China-PAR project显示文摘Existing evidence on the relationship between cardiovascular health(CVH) metrics and cardiovascular disease(CVD) was primarily derived from western populations. We aimed to evaluate the benefits of ideal CVH metrics on preventing incident atherosclerotic CVD(ASCVD) in Chinese population. This study was conducted among 93,987 adults from the China-PAR project(Prediction for ASCVD Risk in China) who were followed up until 2015. Cox proportional hazard regression models were used to estimate the hazard ratios(HRs) and their corresponding 95% confidence intervals(CIs) of CVH metrics for the risk of ASCVD, including coronary heart disease(CHD), stroke and ASCVD death. We further estimated the population-attributable risk percentage(PAR%) of these metrics in relation to each outcome. We observed gradient inverse associations between the number of ideal CVH metrics and ASCVD incidence. Compared with participants having ≤2 ideal CVH metrics, the multivariable-adjusted HRs(95% CIs) of ASCVD for those with 3, 4, 5, 6 and 7 ideal CVH metrics were 0.83(0.74–0.93), 0.66(0.59–0.74), 0.55(0.48–0.61), 0.44(0.38–0.50) and 0.24(0.18–0.31), respectively(P for trend <0.0001). Approximately 62.1% of total ASCVD, 38.7% of CHD, 66.4% of stroke, and 60.5% of ASCVD death were attributable to not achieving all the seven ideal CVH metrics. After adjusting effects of ideal health factors, having four ideal health behaviors could independently bring adults health benefits in preventing 17.4% of ASCVD, 18.0% of CHD, 16.7% of stroke, and 10.1% of ASCVD death. Among all the seven CVH metrics, to keep with ideal blood pressure(BP) implied the largest public health gains against various ASCVD events(PAR% between 33.0% and 47.2%), while ideal diet was the metric most difficult to be achieved in the long term. Our study indicates that the more ideal CVH metrics adults have, the less ASCVD burden there is in China. Special efforts of health education and behavior modification should be made on keeping ideal BP and dietary habits in general Chinese population to prevent the epidemic of ASCVD. | Chao Han Fangchao Liu Xueli Yang Jichun Chen Jianxin Li Jie Cao Ying Li Chong Shen Ling Yu Zhendong Liu Xianping Wu Liancheng Zhao Dongshen Hu Xiangfeng Lu Xigui Wu Dongfeng Gu | 2018 | Science China(Life Sciences)2018，61，5： | 60 |
| 2 | Predicting lifetime risk for developing atherosclerotic cardiovascular disease in Chinese population:the China-PAR project显示文摘Evidence on the lifetime risk for atherosclerotic cardiovascular disease(ASCVD) is insufficient;yet,estimating an individual's lifetime risk allows for a comprehensive assessment of ASCVD burden.We developed and validated lifetime risk prediction equations for ASCVD using four large and ongoing prospective cohorts of Chinese,the China-PAR project(Prediction for ASCVD Risk in China).Sexspecific equations were developed using two cohorts(as the derivation cohort) of 21,320 participants.Two other independent cohorts with 14,123 and 70,838 participants were used for their external validation,respectively.We evaluated both calibration and discrimination measures for model performance.Furthermore,we estimated ASCVD-free years lost or excess absolute risk attributable to high 10-year risk(!10.0%) and/or high lifetime risk(!32.8%).After 12.3 years' follow-up of the derivation cohort,1048 ASCVD events and 1304 non-ASCVD deaths were identified.Our sex-specific equations had good internal validation,with discriminant C statistics of 0.776(95% confidence interval [CI]:0.757–0.794) and 0.801(95% CI:0.778–0.825),and calibration χ~2 of 9.2(P = 0.418) and 5.6(P = 0.777) for men and women,respectively.Good external validation was also demonstrated with predicted rates closely matched to the observed ones.Compared with men having both low 10-year and low lifetime risk,men would develop ASCVD 3.0,4.6 and 8.6 years earlier if they had high 10-year risk alone,high lifetime risk alone,or both high 10-year and high lifetime risk at the index age of 35 years,respectively.We developed wellperformed lifetime risk prediction equations that will help to identify those with the greatest potential to avert ASCVD burden after implementation of innovative clinical and public health interventions in China. | Fangchao Liu Jianxin Li Jichun Chen Dongsheng Hu Ying Li Jianfeng Huang Xiaoqing Liu Xueli Yang Jie Cao Chong Shen Ling Yu Zhendong Liu Xianping Wu Liancheng Zhao Xigui Wu Dongfeng Gu Xiangfeng Lu | 2018 | Science Bulletin2018，63，12： | 30 |
| 3 | Review of the uncertainty analysis of groundwater numerical simulation显示文摘Groundwater system is a complex and open system, which is affected by natural conditions and human activities. Natural hydrological processes is conceptualized through relatively simple flow governing equations in groundwater models. Moreover, observation data is always limited in field hydrogeological conditions. Therefore, the predictive results of groundwater simulation often deviate from true values, which is attribute to the uncertainty of groundwater numerical simulation. According to the process of system simulation, the uncertainty sources of groundwater numerical simulation can be divided into model parameters, conceptual model and observation data uncertainties. In addition, the uncertainty stemmed from boundary conditions is sometimes refered as scenario uncertainty. In this paper, the origination and category of groundwater modeling uncertainty are analyzed. The recent progresses on the methods of groundwater modeling uncertainty analysis are reivewed. Furthermore, the researches on the comprehensive analysis of uncertainty sources, and the predictive uncertainty of model outputs are discussed. Finally, several prospects on the deveolpment of groundwater modeling uncetainty analysis are proposed. | WU JiChun ZENG XianKui | 2013 | Chinese Science Bulletin2013，58，25： | 24 |
| 4 | Spatiotemporal variability of permafrost degradation on the Qinghai-Tibet Plateau显示文摘Based on data from six meteorological stations in the permafrost regions, 60 boreholes for long-term monitoring of permafrost temperatures, and 710 hand-dug pits and shallow boreholes on the Qinghai-Tibet Plateau (QTP), the spatiotemporal variability of permafrost degradation was closely examined in relation to the rates of changes in air, surface, and ground temperatures. The de-cadal averages and increases in the mean annual air temperatures (MAATs) from 1961-2010 were the largest and most persistent during the last century. MAATs rose by 1.3℃, with an average increase rate of 0.03℃/yr. The average of mean annual ground surface temperatures (MAGSTs) increased by 1.3℃ at an average rate of 0.03℃/yr. The rates of changes in ground temperatures were -0.01 to 0.07℃/yr. The rates of changes in the depths of the permafrost table were -1 to +10 cm/yr. The areal extent of permafrost on the QTP shrank from about 1.50×106 km2 in 1975 to about 1.26×106 km2 in 2006. About 60% of the shrinkage in area of permafrost occurred during the period from 1996 to 2006. Due to increasing air temperature since the late 1980s, warm (>-1℃) permafrost has started to degrade, and the degradation has gradually expanded to the zones of transitory (-1 to -2℃) and cold (<-2℃) permafrost. Permafrost on the southern and southeastern plateau degrades more markedly. It is projected that the degradation of permafrost is likely to accelerate, and substantial changes in the distributive features and thermal regimes of permafrost should be anticipated. However, regarding the relationships between degrading permafrost and the degradation of rangelands, it is still too early to draw reliable conclusions due to inadequate scientific criteria and evidence. | HuiJun Jin DongLiang Luo ShaoLing Wang LanZhi Lv JiChun Wu | 2011 | Research in Cold and Arid Regions2011，3，4： | 16 |
| 5 | Processes and modes of permafrost degradation on the Qinghai-Tibet Plateau显示文摘Climate warming must lead the mainly air temperature controlled permafrost to degrade.Based on the numerical simulation,the process of permafrost degradation can be divided into five stages,i.e.,starting stage,temperature rising stage,zero geothermal gradient stage,talic layers stage,and disappearing stage,according to the shape of ground temperature profile.Permafrost on the Qinghai-Tibet Plateau (QTP) is generally considered a relic from late Pleistocene,and has been degenerating as a whole during Holocene.According to spatial-temporal compensation,the present thermal state discrepancy of permafrost in different areas on the QTP may correspond with their degradation stages.On the QTP,permafrost in the high and middle mountains belongs to temperature rising stage,the permafrost thermal state is transiting from late rising temperature stage to zero geothermal gradient stage that is distributed in the middle-low-mountains.Permafrost that is in a zero gradient stage mainly appears in the high plateau and valley,whereas the transition from zero gradient stage to talic layers stage of permafrost is located in the vicinity of the lower limit of permafrost,and permafrost is disappearing from margin of perennially frozen ground.There are two modes of perennially frozen ground thawing,thawing from top to bottom and thawing from bottom to top respectively.During the temperature rising stage,when the heat flux in the perennially frozen soil layer is less than that in the unfrozen soil underlying frozen soil layer,the geothermal flux is partly used to thaw the base of permafrost,and permafrost thaws from bottom to top.With the decrease of thermal gradient in the perennially frozen ground,the heat that is used to thaw permafrost base increases,and geothermal heat will be entirely consumed to thaw the base of permafrost until the temperature gradient reaches zero thermal gradient state.On the other hand,the disappearance of permafrost may be delayed by 'thermal offset' and 'seasonal offset' effects in the upper of permafrost layer.When ground surface temperature rises to the level that can counteract the thermal offset effect,heat accumulation in the active layer would start,and the thickness of the active layer increases until a talic layer to appear.This process can be intensified by the 'seasonal anti-offset effect'. | WU JiChun,SHENG Yu,WU QingBai & WEN Zhi State Key Laboratory of Frozen Soil Engineering,Cold and Arid Regions Environmental and Engineering Research Institute,Chinese Academy of Sciences,Lanzhou 730000,China | 2010 | Science China Earth Sciences2010，53，1： | 16 |
| 6 | Fruit and vegetable consumption,cardiovascular disease,and all-cause mortality in China显示文摘Evidence about the response patterns of fruit and vegetable consumption with the risk of cardiovascular disease(CVD)and allcause mortality was inconsistent.These associations were examined using a large-scale,population-based Chinese cohort comprising 100,728 participants.A food-frequency questionnaire was used to assess fruit and vegetable consumption.Outcomes were ascertained by interviewing individuals or their proxies and checking hospital records or death certificates.Cox proportional hazards regression was used to calculate hazard ratios(HRs)with 95% confidence intervals(CIs).At the 736,668 person-years of follow-up,3,677 CVD cases and 5,466 deaths were identified.The multivariable-adjusted HRs for CVD across increasing quartiles of total fruit and vegetable consumption were 1(reference),0.94(95%CI=0.85-1.04),0.89(95%CI=0.80-0.98),and 0.85(95%CI=0.77-0.95).Moreover,participants in the highest quartile displayed a 13% lower risk of all-cause mortality(HR=0.87;95%CI=0.80-0.95).A nonlinear dose-response relation was found for CVD,without additional benefits beyond a consumption of600 g d-1,whereas the all-cause mortality risk decreased along with higher consumption,with a linear trend.These associations remained significant for fruit consumption but not for vegetable consumption.Our findings indicated that greater fruit and vegetable consumption was significantly associated with a lower risk of CVD and all-cause mortality.Increasing fruit and vegetable consumption,especially fruit,in the general population would prevent CVD and premature mortality. | Jun Wang Fangchao Liu Jianxin Li Keyong Huang Xueli Yang Jichun Chen Xiaoqing Liu Jie Cao Shufeng Chen Chong Shen Ling Yu Fanghong Lu Xianping Wu Liancheng Zhao Ying Li Dongsheng Hu Jianfeng Huang Dongfeng Gu Xiangfeng Lu | 2022 | Science China(Life Sciences)2022，65，1： | 8 |
| 7 | Associations of egg consumption with incident cardiovascular disease and all-cause mortality显示文摘Eggs are nutrient-dense while also loaded with abundant cholesterol, thus making the public hesitant about their consumption.We conducted the study to investigate if egg consumption is associated with incident cardiovascular disease(CVD) and all-cause mortality. Using the project of Prediction for Atherosclerotic Cardiovascular Disease Risk in China, we included 102,136 adults free of CVD and assessed their egg consumption with food-frequency questionnaires. CVD endpoints and all-cause mortality were confirmed during follow-ups by interviewing participants or their proxies and checking hospital records/death certificates.The HRs(95% CIs) were calculated using the cohort-stratified Cox regression models. During 777,163 person-years of followup, we identified 4,848 incident CVD and 5,511 deaths. U-shaped associations of egg consumption with incident CVD and allcause mortality were observed. Compared with consumption of 3–<6/week, the multivariable-adjusted HRs(95% CIs) of <1/week and ≥10/week for incident CVD were 1.22(1.11 to 1.35) and 1.39(1.28 to 1.52), respectively. The corresponding HRs(95% CIs) for all-cause mortality were 1.29(1.18 to 1.41) and 1.13(1.04 to 1.24). Our findings identified that both low and high consumption were associated with increased risk of incident CVD and all-cause mortality, highlighting that moderate egg consumption of 3–<6/week should be recommended for CVD prevention in China. | Xue Xia Fangchao Liu Xueli Yang Jianxin Li Jichun Chen Xiaoqing Liu Jie Cao Chong Shen Ling Yu Yingxin Zhao Xianping Wu Liancheng Zhao Ying Li Jianfeng Huang Xiangfeng Lu Dongfeng Gu | 2020 | Science China(Life Sciences)2020，63，9： | 7 |
| 8 | Simulation of regional land subsidence in the southern Yangtze Delta显示文摘Investigation of the deformation characteristics of individual hydrostratigraphic units is the key to construct a regional land subsidence model. All of 12 hydrostratigraphic units in the study area were discussed throughout. On the basis of the measured data of groundwater level, five kinds of changing patterns of groundwater level were deduced and the relationship between the deformation characteris-tics of aquifer units and the corresponding changing patterns of groundwater level was discussed. The study area is 1.7×104 km2, where the geological condition is complex. The changing patterns of groundwater level the hydrostratigraphic units have experienced vary from site to site and from time to time. Consequently, the deformation characteristics of units are sophisticated. An identical hydros-tratigraphic unit may exhibit different deformation characteristics, such as elasticity, elasto-plasticity, visco-elasticity, and visco-elasto-plasticity, at different sites or during different periods, not to mention the different units. The existing models are difficult to describe the complex visco-elasto-plastic con-stitutive law under the condition of land subsidence. So the Merchant’s model was modified to depict the visco-elasto-plastic behavior of units. Then a three-dimensional flow model with variable parame-ters and a vertical one-dimensional subsidence model were constructed and coupled. The coupled model was applied in simulating land subsidence in the southern Yangtze Delta and a satisfactory re-sult was obtained. The simulation results show that the new coupled model can depict the complex geological conditions and describe the developing process of land subsidence very well in the south-ern Yangtze Delta. The new model can surely be used to predict land subsidence in the future, which is very helpful to taking measurements to control land subsidence. | XUE YuQun WU JiChun ZHANG Yun YE ShuJun SHI XiaoQing WEI ZiXin LI QinFen YU Jun | 2008 | Science China Earth Sciences2008，51，6： | 6 |
| 9 | Study on the Metallogenetism of Sub-mantle Plume and Mantle Branches in the Gold Mineralization Concentration Area of Northwest Jiaodong Peninsula显示文摘The northwest of Jiaodong peninsula is characterized by its greatest gold concentration area, enormous gold reserves and limited time interval(115±5Ma) of gold mineralization in China. Studies show that the east area of north China began its mantle plume evolution since the Yanshanian movement, and the Laiyang sub-mantle plume and its surrounding mantle branches such as those in Guojiadian, Aishan and Panshidian were formed in the mineralization concentration area of northwestern Jiaodong peninsula. With the development of mantle plume → sub-mantle plume → mantle branch → favorable expending structures, the deep-derived hydrothermal fluid moved up to the favorable places, such as brittle-ductile or ductile-brittle shearing zones, the internal and external contact zones of intrusions, dense fracturing zones and the contact zones between dikes and countryrocks, and concentrated into deposits. Then the gold mineralization concentration zones that are centralized on mantle branches were formed. This study takes Guojiadian mantle branch as an example to discuss their metallogenetism and conclude the metallogenetic mode. | NIU Shuyin CHENG Guangsuo ZHANG Jianzhen SUN Aiqun MA Baojun ZHANG Fuxiang WANG Baode XU Meng WU Jichun ZHAO Rongxin WANG Shanfei | 2014 | Acta Geologica Sinica(English Edition)2014，88，5： | 4 |
| 10 | Isolation,Identification,and Characterization of an Aluminum-Tolerant Bacterium Burkholderia sp.SB1 from an Acidic Red Soil显示文摘Aluminum(Al) toxicity usually occurs in acidic soils worldwide, which is detrimental to the growth of organisms. An Al-tolerant bacterium, SB1, was isolated from an acidic red soil of Chingkang Mountain, located in Jiangxi Province of China. Polyphasic analysis,including a 16 S rDNA phylogenetic tree as well as morphological and physicochemical properties, revealed that the isolate was a gramnegative, rod-shaped bacterium, which was recognized as Burkholderia sp. SB1 and had extreme acidity tolerance(pH 2.2) and excellent Al resistance(270 mg L^(-1) Al^(3+)). It could remove Al by up to 97.7% at a concentration of 54 mg L^(-1) Al^(3+). SB1 behavior under different temperatures and antibiotics was also examined. SB1 preferred moderate temperature conditions, ranging from 25 to37?C, and exhibited notable resistance to multiple antibiotics(including ampicillin, streptomycin, and tetracycline), except for being sensitive to chloramphenicol. Therefore, as the first reported bacterium to possess favorable Al resistance and excellent Al removal,Burkholderia sp. SB1 can potentially be used as an agent for bioremediation of Al-contaminated acidic red soils. | HUANG Shoucheng WANG Xiaodong LIU Xu HE Genhe WU Jichun | 2018 | Pedosphere2018，28，6： | 4 |
| 11 | A Hybrid Multi-Objective Evolutionary Algorithm for Optimal Groundwater Management under Variable Density Conditions显示文摘In this paper,a new hybrid multi-objective evolutionary algorithm(MOEA),the niched Pareto tabu search combined with a genetic algorithm(NPTSGA),is proposed for the management of groundwater resources under variable density conditions.Relatively few MOEAs can possess global search ability contenting with intensified search in a local area.Moreover,the overall searching ability of tabu search(TS) based MOEAs is very sensitive to the neighborhood step size.The NPTSGA is developed on the thought of integrating the genetic algorithm(GA) with a TS based MOEA,the niched Pareto tabu search(NPTS),which helps to alleviate both of the above difficulties.Here,the global search ability of the NPTS is improved by the diversification of candidate solutions arising from the evolving genetic algorithm population.Furthermore,the proposed methodology coupled with a density-dependent groundwater flow and solute transport simulator,SEAWAT,is developed and its performance is evaluated through a synthetic seawater intrusion management problem.Optimization results indicate that the NPTSGA offers a tradeoff between the two conflicting objectives.A key conclusion of this study is that the NPTSGA keeps the balance between the intensification of nondomination and the diversification of near Pareto-optimal solutions along the tradeoff curves and is a stable and robust method for implementing the multi-objective design of variable-density groundwater resources. | YANG Yun WU Jianfeng SUN Xiaomin LIN Jin WU Jichun | 2012 | Acta Geologica Sinica(English Edition)2012，86，1： | 4 |
| 12 | An Estimation of Ground Ice Volumes in Permafrost Layers in North- eastern Qinghai-Tibet Plateau, China显示文摘The ground ice content in permafrost serves as one of the dominant properties of permafrost for the study of global climate change, ecology, hydrology and engineering construction in cold regions. This paper initially attempts to assess the ground ice volume in permafrost layers on the Qinghai-Tibet Plateau by considering landform types, the corresponding lithological composition, and the measured water content in various regions. An approximation demonstrating the existence of many similarities in lithological composition and water content within a unified landform was established during the calculations. Considerable knowledge of the case study area, here called the Source Area of the Yellow(Huanghe) River(SAYR) in the northeastern Qinghai-Tibet Plateau, has been accumulated related to permafrost and fresh water resources during the past 40 years. Considering the permafrost distribution, extent, spatial distribution of landform types, the ground ice volume at the depths of 3.0–10.0 m below the ground surface was estimated based on the data of 101 boreholes from field observations and geological surveys in different types of landforms in the permafrost region of the SAYR. The total ground ice volume in permafrost layers at the depths of 3.0–10.0 m was approximately(51.68 ± 18.81) km^3, and the ground ice volume per unit volume was(0.31 ± 0.11) m^3/m^3. In the horizontal direction, the ground ice content was higher in the landforms of lacustrine-marshland plains and alluvial-lacustrine plains, and the lower ground ice content was distributed in the erosional platforms and alluvial-proluvial plains. In the vertical direction, the volume of ground ice was relatively high in the top layers(especially near the permafrost table) and at the depths of 7.0–8.0 m. This calculation method will be used in the other areas when the necessary information is available, including landform type, borehole data, and measured water content. | WANG Shengting SHENG Yu LI Jing WU Jichun CAO Wei MA Shuai | 2018 | Chinese Geographical Science2018，28，1： | 4 |
| 13 | Modeling Regional and Local-scale Permafrost Distribution in Qinghai-Tibet Plateau Using Equivalent-elevation Method显示文摘This study proposes an equivalent-elevation method to evaluate the integrated effects of latitude and elevation on regional and local-scale permafrost distribution in the Qinghai-Tibet Plateau,and to model the general permafrost-distribution patterns in regional and local-scale area.It is found that the Gaussian curve―an empirical model describing the relation between variations of altitudinal permafrost lower limit (PLL) and latitude in the Northern Hemisphere―could be applied in regional-and local-scale areas in the Qinghai-Tibet Plateau in a latitude-sensitive interval of 30°-50°N.The curve was then used to evaluate the latitudinal effect on permafrost distribution through transforming the latitudinal effect into a kind of altitudinal difference of PLL.This study then calculated the local equivalent-elevation value by overlaying the altitudinal difference of PLL onto real elevation at a certain location.The equivalent-elevation method was verified in an experimental subwatershed of the Qinghai-Tibet Plateau.However,feasibility of the method should be further tested in order to extend for future studies.The use of equivalent-elevation values can build a platform for comparing the regional general permafrost distribution in the plateau,and for basing further evaluations of local factors' effects on regional permafrost distribution. | LI Jing SHENG Yu WU Jichun WANG Jie ZHANG Bo YE Baisheng ZHANG Xiumin QIN Xiang | 2012 | Chinese Geographical Science2012，22，3： | 3 |
| 14 | Mountain permafrost distribution modeling using Multivariate Adaptive Regression Spline (MARS) in the Wenquan area over the Qinghai-Tibet Plateau显示文摘In high mountainous areas, the development and distribution of alpine permafrost is greatly affected by macroand micro-topographic factors. The effects of latitude, altitude, slope, and aspect on the distribution of permafrost were studied to understand the distribution patterns of permafrost in Wenquan on the Qinghai-Tibet Plateau. Cluster and correlation analysis were performed based on 30 m Global Digital Elevation Model (GDEM) data and field data obtained using geophysical exploration and borehole drilling methods. A Multivariate Adaptive Regression Spline model (MARS) was developed to simulate permafrost spatial distribution over the studied area. A validation was followed by comparing to 201 geophysical exploration sites, as well as by comparing to two other models, i.e., a binary logistic regression model and the Mean Annual Ground Temperature model (MAGT). The MARS model provides a better simulation than the other two models. Besides the control effect of elevation on permafrost distribution, the MARS model also takes into account the impact of direct solar radiation on permafrost distribution. | XiuMin Zhang ZhuoTong Nan JiChun Wu ErJi Du Tong Wang YanHui You | 2012 | Research in Cold and Arid Regions2012，4，5： | 3 |
| 15 | Bioaccessibility and health risk of arsenic and heavy metals (Cd, Co, Cr, Cu, Ni, Pb, Zn and Mn) in TSP and PM2.5 in Nanjing, China显示文摘 | Xin Hu Yun Zhang Zhuhong Ding Tijian Wang Hongzhen Lian Yuanyuan Sun Jichun Wu | 2012 | Atmospheric Environment2012，，： | 2 |
| 16 | Adverse associations of sedentary behavior with cancer incidence and all-cause mortality:A prospective cohort study显示文摘Background:Inconsistent results have been reported in developed countries for relationships between sedentary behavior and cancer incidence and mortality,and evidence from the Chinese population is scarce.This study aimed to investigate such relationships in large Chinese population-based prospective cohorts and to explore the joint effect and interaction of sedentary behavior and moderate-to-vigorous physical activity(MVPA)on these relationships.Methods:We included 95,319 Chinese adults without cancer from 3 large cohorts and assessed their sedentary behavior and physical activity with a unified questionnaire.Cancer incidence and mortality were confirmed by interviewing participants or their proxies and checking hospital records and death certificates.Hazard ratios(HRs)and 95%confidence intervals(95%CIs)for cancer and mortality were estimated using Cox proportional hazards regression models.Results:During 559,002 person-years of follow-up,2388 cancer events,1571 cancer deaths,and 4562 all-cause deaths were recorded.Sedentary behavior was associated with increased risk of developing cancer and deaths in a doseresponse manner.The multivariable-adjusted HRs(95%CIs)were the following:HR=1.16,95%CI:1.01-1.33;HR=1.24,95%CI:1.04-1.48;and HR=1.15,95%CI:1.04-1.28 for cancer incidence,cancer mortality,and all-cause mortality,respectively,for those having≥10 h/day of sedentary time compared with those having<6 h/day of sedentary time.Sedentary populations(≥10 h/day)developed cancer or died 4.09 years and 2.79 years earlier,respectively,at the index age of 50 years.Failure to achieve the recommended level of MVPA may further aggravate the adverse associations,with the highest cancer and mortality risks being observed among participants with both≥10 h/day of sedentary time and<150 min/week of MVPA.Limitations of this study include the fact that physical activity information was obtained via questionnaire instead of objective measurement and that there were insufficient incident cases for the analysis of associations between sedentary behavior and site-specific cancers.Conclusion:Sedentary behavior was associated with an increased risk of cancer and all-cause mortality among Chinese adults,especially for those with≥10 h/day of sedentary time.It is necessary to reduce sedentary time,in addition to increasing MVPA levels,for the prevention of cancer and premature death. | Yuan Lin Qiong Liu Fangchao Liu Keyong Huang Jianxin Li Xueli Yang Xinyan Wang Jichun Chen Xiaoqing Liu Jie Cao Chong Shen Ling Yu Fanghong Lu Xianping Wu Liancheng Zhao Ying Li Dongsheng Hu Xiangfeng Lu Jianfeng Huang Dongfeng Gu | 2021 | Journal of Sport and Health Science2021，10，5： | 2 |
| 17 | Seawater intrusion in the coastal area of Laizhou Bay,China:1 Distribution of sea- water intrusion and its Hydrochemical characteristics显示文摘 | Xue Yuqun Wu Jichun | 1993 | Ground Water1993，31，4： | 1 |
| 18 | Seawater intrusion in the coastal areal of Laizhou Bay,China:2 Seawater instrusion moni- oring显示文摘 | Wu Jichun Xue Yuqun | 1993 | Ground Water1993，31，5： | 1 |
| 19 | Lead contamination and transfer in urban environmental compartments analyzed by lead levels and isotopic compositions显示文摘 | Xin Hu Yuanyuan Sun Zhuhong Ding Yun Zhang Jichun Wu Hongzhen Lian Tijian Wang | 2014 | Environmental Pollution2014，，： | 1 |
| 20 | Numerical Simulation of Land Subsidence Induced by Groundwa- ter over Exploitation in Su - Xi - Chang Area, China 显示文摘 | Wu Jichun Shi Xiaoqing Ye Shujun | 2009 | Environmental Geology2009，57，6： | 1 |
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