5篇
您的检索式：作者名="Jidong Zuo"
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| 1 | Bioactive composite gradient coa- tings of nano-hydroxyapatitdpolyamide66 fabricated on polyamide66 substrates 显示文摘 | Huang Di Zuo Yi Li Jidong | 2012 | Joumal of the Royal Society Interface2012，9，72： | 1 |
| 2 | A baicalin-loaded coaxial nanofiber scaffold regulated inflammation and osteoclast differentiation for vascularized bone regeneration显示文摘We demonstrate a simple,effective and feasible method to address the shrinkage of Poly(lactic-co-glycolic acid)(PLGA)through a core-shell structure fiber strategy.The results revealed that introducing size-stable poly-caprolactone(PCL)as the core fiber significantly improved the PLGA-based fibrous scaffold’s dimensional maintenance.We further utilized fish collagen to modify the PLGA shell layer(PFC)of coaxial fibers and loaded baicalin(BA)into the PCL core layer(PCL-BA)to endow fibrous scaffold with more functional biological cues.The PFC/PCL-BA fibrous scaffold promoted the osteogenic differentiation of bone mesenchymal stem cells and stimulated the RAW264.7 cells to polarize into a pro-reparative phenotype.Importantly,the in vivo study demonstrated that the PFC/PCL-BA scaffold could regulate inflammation and osteoclast differentiation,favor neovascularization and bone formation.This work tactfully combined PLGA and PCL to establish a drug release platform based on the core-shell fibrous scaffold for vascularized bone regeneration. | Shue Jin Jing Gao Renli Yang Chen Yuan Ruili Wang Qin Zou Yi Zuo Meifang Zhu Yubao Li Yi Man Jidong Li | 2022 | Bioactive Materials2022，7，2： | 1 |
| 3 | A dog carrying mutations in AVP-NPII exhibits key features of central diabetes insipidus显示文摘Central diabetes insipidus(CDI)is a rare disease characterized by the excretion of copious amounts of diluted urine(polyuria),excess water intake(polydipsia),and a rise in serum sodium concentration(hypernatremia)(Christ-Crain et al.,2019).The neuropeptide arginine-vasopressin(AVP)is synthesized as a preprohormone along with its carrier protein neurophysin II(NPII)in hypothalamic supraoptic(SON)and paraventricular(PVN)magnocellular neurons,stored in the posterior pituitary,and secreted into the circulation. | Huijuan Xu Haiyang Hao Shirui Wang Xueru Liu Wen Lyu Zhentao Zuo Yan Zhuo Jidong Mi Yong Q.Zhang Rui Tian Huijuan Zhu | 2023 | Journal of Genetics and Genomics2023，50，4： | 0 |
| 4 | 香菇引起的小肠梗阻两例报道显示文摘The shiitake mushroom(Lentinula edodes),known as Xiang-gu in China,has been an important component of Asian cuisine for hundreds of years.Although not easily digestible,there are few reports of them causing bowel obstruction.We present two cases of small bowel obstruction due to a shiitake mushroomrequiring surgical intervention.Two patients who did not have any teeth and did not use dentures presented with intestinal bowel obstruction and were referred to the Emergency Department of our hospital after eating a meal including shiitake mushrooms without cutting.The first patient underwent an emergency laparotomy and a semental small bowel resection and the other underwent laparoscopic small bowel incision for removal of a foreign body.The causes of the small bowel obstruction for the two patients were uncut shiitake mushrooms in the small bowel.The two patients recovered uneventfully post-operatively. | Jinfu Tan Kaitao Yuan Jidong Zuo Weigang Dai Yujie Yuan Weidong Feng Min Tan Jinping Ma | 2019 | Gastroenterology Report2019，7，4： | 0 |
| 5 | Construction and Properties of Simvastatin and Calcium Phosphate Dual-Loaded Coaxial Fibrous Membranes with Osteogenic and Angiogenic Functions显示文摘The ideal Guided Bone Regeneration(GBR)membrane is required to have good biocompatibility,space maintenance ability,appropriate degradation rate,and preferably can guide the regeneration of vascularized bone tissue.In this study,Simvastatin(SIM)and calcium Phosphate(CaP)were encapsulated in a Polycaprolactone(PCL)/Chitosan(CS)core-shell structural fibrous membranes via coaxial electrospinning technology.The results showed that loaded SIM in the core of the core-shell structure fibrous membranes could sustainably release the drug for more than two months and upregulate the angiogenic marker of Bone Mesenchymal Stem Cells(BMSCs).Adding a certain amount of CaP to the shell layer provided more sites for the mineralization and synergistic with SIM to promote osteogenic differentiation of BMSCs in vitro.The intramuscular implantation experiments in rabbits suggested a normal early inflammation and enhanced vascularization induced by the SIM-loaded fibrous membranes.This study proposed an effective strategy to prepare a dual-loaded core-shell fibrous membrane for guided vascularized bone tissue regeneration. | Chang Liu Dan Deng Jing Gao Shue Jin Yi Zuo Yubao Li Jidong Li | 2022 | Journal of Bionic Engineering2022，19，6： | 0 |
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