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3篇 您的检索式:作者名="Jinmeng Sun"
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1Present and future of functionalized Cu current collectors for stabilizing lithium metal anodes显示文摘Li metal has been recognized as the most promising anode materials for next-generation high-energy-density batteries,however,the inherent issues of dendrite growth and huge volume fluctuations upon Li plating/stripping normally result in fast capacity fading and safety concerns.Functionalized Cu current collectors have so far exhibited significant regulatory effects on stabilizing Li metal anodes(LMAs),and hold a great practical potential owing to their easy fabrication,low-cost and good compatibility with the existing battery technology.In this review,a comprehensive overview of Cu-based current collectors,including planar modified Cu foil,3D architectured Cu foil and nanostructured 3D Cu substrates,for Li metal batteries is provided.Particularly,the design principles and strategies of functionalized Cu current collectors associated with their functionalities in optimizing Li plating/stripping behaviors are discussed.Finally,the critical issues where there is incomplete understanding and the future research directions of Cu current collectors in practical LMAs are also prospected.This review may shed light on the critical understanding of current collector engineering for high-energy-density Li metal batteries.Yuhang Liu Yifan Li Jinmeng Sun Zhuzhu Du Xiaoqi Hu Jingxuan Bi Chuntai Liu Wei Ai Qingyu Yan 2023Nano Research Energy2023,2,1:1
2Advances in the Emerging Gradient Designs of Li Metal Hosts显示文摘Developing host has been recognized a potential countermeasure to circumvent the intrinsic drawbacks of Li metal anode(LMA),such as uncontrolled dendrite growth,unstable solid electrolyte interface,and infinite volume fluctuations.To realize proper Li accommodation,particularly bottom-up deposition of Li metal,gradient designs of host materials including lithiophilicity and/or conductivity have attracted a great deal of attention in recent years.However,a critical and specialized review on this quickly evolving topic is still absent.In this review,we attempt to comprehensively summarize and update the related advances in guiding Li nucleation and deposition.First,the fundamentals regarding Li deposition are discussed,with particular attention to the gradient design principles of host materials.Correspondingly,the progress of creating diferent gradients in terms of lithiophilicity,conductivity,and their hybrid is systematically reviewed.Finally,future challenges and perspective on the gradient design of advanced hosts towards practical LMAs are provided,which would provide a useful guidance for future studies.Wanqing Guan Xiaoqi Hu Yuhang Liu Jinmeng Sun Chen He Zhuzhu Du Jingxuan Bi Ke Wang Wei Ai 2022Research2022,,4:0
3STIM1 overexpression in hypoxia microenvironment contributes to pancreatic carcinoma progression显示文摘Objective: Stromal interaction molecule 1(STIM1) overexpression has been reported to play an important role in progression of several cancers. However, the mechanism of STIM1 overexpression and its relationship with hypoxia in pancreatic ductal adenocarcinoma(PDAC) remains unclear.Methods: STIM1 and HIF-1α expression was tested using immunohistochemistry in tissue microarray(TMA) including pancreatic cancer and matched normal pancreatic tissues, and their relationships with clinicopathological parameters were statistically analyzed. q-PCR, Western blot, Ch IP, and luciferase assay were employed to 030 analyze transcriptional regulation between HIF-1α and STIM1 in pancreatic cancer PANC-1 cells.Results: Both STIM1 and HIF-1α showed higher positive rates and up-regulated expression in cancer tissues compared to that of normal tissues(P < 0.05). The Kaplan–Meier method revealed that higher HIF-1α and STIM1 expression levels were significantly correlated with decreased disease-free survival(P = 0.025 and P = 0.029, respectively). The expression of HIF-1α showed a significant positive correlation with that of STIM1 in cancer tissues(rs = 0.3343, P = 0.0011) and pancreatic cancer cell lines.Furthermore, Ch IP and luciferase assays confirmed that HIF-1α bound to the STIM1 promoter and regulated its expression in PANC-1 cells.Conclusions: In hypoxia microenvironment, up-regulated expression of STIM1 mediated by HIF-1α promotes PDAC progression. HIF-1α and STIM1 are potential prognostic markers and/or therapeutic targets for PDAC treatment.Jian Wang Junling Shen Kaili Zhao Jinmeng Hu Jiuxing Dong Jianwei Sun 2019Cancer Biology & Medicine2019,16,1:0
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