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| 1 | Pollution characteristics of organic and elemental carbon in PM_(2.5) in Xiamen,China显示文摘Xiamen,located on the southeastern coastal line of China,is undergoing rapid urbanization and industrialization,so its air quality has a trend of degradation.However,studies on level,temporal and spatial changes of fine particles (PM 2.5) and their carbonaceous fractions are scarce.In this article,abundance,sources,seasonal and spatial variations,distribution of organic carbon (OC) and elemental carbon (EC) in PM 2.5,were studied at suburban,urban and industrial sites in Xiamen during four season-representative months in 2009-2010.PM 2.5 samples were collected with middle volume sampler and were analyzed for OC and EC with thermal optical transmittance (TOT) method.Results showed that the annual average PM 2.5 concentrations were 63.88-74.80 μg/m 3 at three sites.While OC and EC concentrations were in the range of 15.81-19.73 μg/m 3 and 2.74-3.49 μg/m 3,respectively,and clearly presented the summerminima and winter maxima in this study.The carbonaceous aerosol accounted for 42.8%-47.3% of the mass of PM 2.5.The annual average of secondary organic carbon (SOC) concentrations in Xiamen were 9.23-11.36 μg/m 3,accounting for approximately 56% of OC.Strong correlations between OC and EC was found in spring (R 2=0.50) and autumn (R 2=0.73),suggesting that there were similar emission and transport processes for carbonaceous aerosols in these two seasons,while weak correlations were found in summer (R 2=0.33) and winter (R 2=0.41).The OC/EC ratios in PM 2.5 varied from 2.1 to 8.7 with an annual average of 5.7,indicating that vehicle exhaust,coal smoke and biomass burning were main source apportionments of carbonaceous fractions in Xiamen. | Fuwang Zhang Jinping Zhao Jinsheng Chen Ya Xu Lingling Xu | 2011 | Journal of Environmental Sciences2011，23，8： | 27 |
| 2 | Chemical characteristics of PM_(2.5) during haze episodes in the urban of Fuzhou,China显示文摘Atmospheric fine particles(PM_(2.5)) were collected in this study with middle volume samplers in Fuzhou,China,during both normal days and haze days in summer(September 2007) and winter(January 2008).The concentrations,distributions,and sources of polycyclic aromatic hydrocarbons(PAHs),organic carbon(OC),elemental carbon(EC),and water soluble inorganic ions(WSIIs) were determinated.The results showed that the concentrations of PM2.5,PAHs,OC,EC,and WSIIs were in the orders of haze > normal and winter > summer.The dominant PAHs of PM2.5 in Fuzhou were Fluo,Pyr,Chr,BbF,BkF,BaP,BghiP,and IcdP,which represented about 80.0%of the total PAHs during different sampling periods.The BaPeq concentrations of ∑PAHs were 0.78,0.99,1.22,and 2.43 ng/m3 in summer normal,summer haze,winter normal,and winter haze,respectively.Secondary pollutants(SO_4^(2-),NO_3^-,NH_4^+.and OC) were the major chemical compositions of PM2.5,accounting for 69.0%,55.1%,63.4%,and 64.9%of PM2.5 mass in summer normal,summer haze,winter normal,and winter haze,respectively.Correspondingly,secondary organic carbon(SOC) in Fuzhou accounted for 20.1%,48.6%,24.5%,and 50.5%of OC.The average values of nitrogen oxidation ratio(NOR) and sulfur oxidation ratio(SOR) were higher in haze days(0.08 and 0.27) than in normal days(0.05 and 0.22).Higher OC/EC ratios were also found in haze days(5.0) than in normal days(3.3).Correlation analysis demonstrated that visibility had positive correlations with wind speed,and negative correlations with relative humidity and major air pollutants.Overall,the enrichments of PM_(2.5),OC,EC,SO_4^(2-),and NO_3^- promoted haze formation.Furthermore,the diagnostic ratios of IcdP/(IcdP + BghiP),IcdP/BghiP,OC/EC,and NO_3^-/SO_4^(2-) indicated that vehicle exhaust and coal consumption were the main sources of pollutants in Fuzhou. | Fuwang Zhang Lingling Xu Jinsheng Chen Xiaoqiu Chen Zhenchuan Niu Tong Lei Chunming Li Jinping Zhao | 2013 | Particuology2013，11，3： | 19 |
| 3 | Distribution of Pacific-origin water in the region of the Chukchi Plateau in the Arctic Ocean in the summer of 2003显示文摘The upper ocean thermohaline structures in the region of the Chukchi Plateau are analyzed with the hydrographic data collected by the Chinese National Arctic Research Expedition in the summer of 2003. Three types of the Pacific-origin water were found in the upper ocean, Alaska Coastal Water (ACW), summer Bering Sea Water (sBSW) and winter Bering Sea Water (wBSW) are indicated by two maximums temperature and one minimum temperature, piling up from the upper to the lower respectively. The extreme warm ACW with a maximum temperature of 1.62 ℃ was found in the southwestern Canada Basin at a depth of about 50 m. A pathway of the ACW into the basin from its adjacent area did not existed in the expedition period. So it is speculated that the extreme warm feature of the ACW was formed locally in 2003. The relative weak ACW occurred to the east of the Chukchi Cap and in the southern Chukchi Abyssal Plain. The latter one might originate from a warm downwelling that existed in a small canyon at the shelf break of the Chukchi Sea. The sBSW without the ACW was found only at the southwestern flank of the Chukchi Cap. The ACW and the sBSW were not found in the northernmost station at 81°N,which indicates the north boundary of the upper Pacific-origin water in the Canada Basin. The wBSW, which existed in all deep stations,was exactly uniform at temperature. The difference of the core potential temperature of the wBSW in the deep regions is only 0.08 ℃. | SHI Jiuxin CAO Yong ZHAO Jinping GAO Guoping JIAO Yutian LI Shujiang | 2005 | Acta Oceanologica Sinica2005，24，6： | 15 |
| 4 | Water mass of the northward throughflow in the Bering Strait in the summer of 2003显示文摘The temperature and salinity data obtained by the Chinese national arctic research expedition (CHINARE2003) are used to study the water structure in the Bering Strait and ambient regions. Four water masses appeared in the research region: the intermediate Bering Sea water mass (IBWM), the Alaska coastal water (ACW), the Anadyr water (AW) and the Bering shelf water (BSW). The AW originates from the IBWM, but the upper layer water has been greatly altered. In the cruise on 28/29 July 2003, there were only the BSW and ACW in a section across the Bering Strait (BS section), but in the September 12/13 cruise, the AW, BSW and ACW flowed parallelly into the Bering Strait. The upper waters of these water masses were all altered due to ice melting, runoff, solar radiation, and wind mixing. The waters in the central and northern parts of Bering Strait stratified by two uniform layers,were expressed as the typical feature of the water masses originating from the pacific. A two-layer structure also dominated the vertical stratification in most part of the Chukchi Sea. An obvious subseasonal variation was observed in the BS section, which caused varying transportation of fresh water, heat, and substance, and produced a long-term and extensive impact on the Arctic Ocean. | ZHAO Jinping SHI Jiuxin GAO Guoping JIAO Yutian ZHANG Hongxin | 2006 | Acta Oceanologica Sinica2006，25，2： | 10 |
| 5 | Amorphous NiFeB nanoparticles realizing highly active and stable oxygen evolving reaction for water splitting显示文摘为发展反应(OER ) 的氧的高度有效、便宜的催化剂的发展为支持切开的水的全面效率是极其迫切的。此处,我们与改变 Fe 的原子比率到报导一系列非结晶的 NiFeB nanoparticles 的制造(Ni + Fe )( 由一个灵巧的化学减小的方法的 Fe ) 。非结晶的 NiFeB ( Fe = 0.20 ) nanoparticles ,联合优点在充实硼酸盐的 NiFeOOH 催化表面层,内在的非结晶的 nanostructures ,和 Fe 的优化的度的 situ 形成做,向在大量 pH 的 OER 的显示的高度活跃的 electrocatalytic 性能珍视(从对中立条件碱)。催化剂在 10 妈 / 厘米 2 在玻璃质的碳上与 43 mV/dec 的一个 Tafel 斜坡在 Ni 泡沫和 251 mV 上与 40 mV/dec 的一个 Tafel 斜坡展出了 216 mV 的相对低的过电位在 1 M KOH 溶液,比商业 RuO 2 的表明大得多的 OER 效率。NiFeB 的 OER 表演测试的长期的稳定性( Fe = 0.20 ) 由 chronoamperometry (过电位()= 320 mV ) 超过 200 h 没揭示降级的证据。灵巧的、可伸缩的合成和高度活跃的水氧化为 OER electrocatalysis 使 NiFeB nanoparticles 很吸引人。 | Guang Liu Dongying He Rui Yao Yong Zhao Jinping Li | 2018 | Nano Research2018，11，3： | 10 |
| 6 | Efficient Synthesis of Graphene Nanoribbons Sonochemically Cut from Graphene Sheets显示文摘We report a facile approach to synthesize narrow and long graphene nanoribbons (GNRs) by sonochemically cutting chemically derived graphene sheets (GSs). The yield of GNRs can reach ~5 wt% of the starting GSs. The resulting GNRs are several micrometers in length, with ~75% being single-layer, and ~40% being narrower than 20 nm in width. A chemical tailoring mechanism involving oxygen-unzipping of GSs under sonochemical conditions is proposed on the basis of experimental observations and previously reported theoretical calculations;it is suggested that the formation and distribution of line faults on graphite oxide and GSs play crucial roles in the formation of GNRs. These results open up the possibilities of the large-scale synthesis and various technological applications of GNRs. | Zhong-Shuai Wu Wencai Ren Libo Gao Bilu Liu Jinping Zhao Hui-Ming Cheng | 2010 | Nano Research2010，3，1： | 10 |
| 7 | Characterization of polycyclic aromatic hydrocarbons and gas/particle partitioning in a coastal city, Xiamen, Southeast China显示文摘An intensive sampling program had been undertaken in autumn (October, 2008) and winter (December, 2008 and January, 2009) at urban (Xiamen University and Xianyue residential area), suburban (Institute of Urban Environment), industrial area (Lulian Hotel) and background (Tingxi Reservoir) in Xiamen, Fujian Province, to characterize the atmospheric concentration and gas-particle phase partitioning of PAHs. The average concentration of total PAHs in winter was almost 1.7 times higher than those in autumn. The log scale plot of Kp versus sub-cooled liquid vapor pressure (P0L) for all the data of autumn and winter season samples gave significantly different slopes. The slope for the winter samples (-0.72) was steeper than that for the autumn samples (-0.58). The partitioning results indicated that slope values varied depending on characteristics of specific site, source region and meteorological conditions which play important roles in the partitioning of PAHs. In addition, local emission sources had a stronger effect on partitioning results than long-transported polluted plume. The sources of PAHs in five sampling sites in Xiamen also have been discussed initially. Diagnostic ratios showed that the primary source of PAHs in urban, suburban and industrial area was from vehicle exhausts. While emission from petrochemical factory and power plant was another main contributor to industrial area. | Jinping Zhao Fuwang Zhang Jinsheng Chen Ya Xu | 2010 | Journal of Environmental Sciences2010，22，7： | 9 |
| 8 | Optimal sensor placement in health monitoring of suspension bridge显示文摘Structural health monitoring(SHM) provides an effective approach to ensure the safety of structures.However,with the restriction of the cost of sensor system and data processing,only a small number of sensors could be available in the health monitoring system(HMS).In order to obtain the best identification of structural characteristics,optimal sensor placement(OSP) becomes an inevitable task in the design of HMS.This paper introduces the process for determining the OSP in HMS of a suspension bridge,in which four different OSP methods have been investigated,including the effective independence(EI) method,the effective independence driving-point residue(EFI-DPR) method,the minimized modal assurance criterion(minMAC) method and the principal subset selection-based extended EI(PSS-EI) method.Then,three criteria,which are modal assurance matrix(MAC),condition number(CN) of mode shape matrix and determinant of Fisher information matrix(FIM),were employed to evaluate the effect of the OSP methods respectively.The result showed that the PSS-EI method developed has the ability to guarantee the highest determinant of FIM,a relatively small off-diagonal term of MAC and agreeable CN,as well as the deployment of sensors in a uniform and symmetric fashion for the studied bridge.Finally,the scheme obtained by PSS-EI was adopted in the HMS. | LI BinBin LI DongSheng ZHAO XueFeng OU JinPing | 2012 | Science China(Technological Sciences)2012，55，7： | 9 |
| 9 | Normal Structure and Function of Endothecium Chloroplasts Maintained by ZmMs33-Mediated Lipid Biosynthesis in Tapetal Cells Are Critical for Anther Development in Maize显示文摘Genic male sterility(GMS)is critical for heterosis utilization and hybrid seed production.Although GMS mutants and genes have been studied extensively in plants,it has remained unclear whether chloroplast-associated photosynthetic and metabolic activities are involved in the regulation of anther development.In this study,we characterized the function of ZmMs33/ZmGPAT6,which encodes a member of the glycerol-3-phosphate acyltransferase(GPAT)family that catalyzes the first step of the glycerolipid synthetic pathway.We found that normal structure and function of endothecium(En)chloroplasts maintained by ZmMs33-mediated lipid biosynthesis in tapetal cells are crucial for maize anther development.ZmMs33 is expressed mainly in the tapetum at early anther developmental stages and critical for cell proliferation and expansion at late stages.Chloroplasts in En cells of wild-type anthers function as starch storage sites before stage 10 but as photosynthetic factories since stage 10 to enable starch metabolism and carbohydrate supply.Loss of ZmMs33 function inhibits the biosynthesis of glycolipids and phospholipids,which are major components of En chloroplast membranes,and disrupts the development and function of En chloroplasts,resulting in the formation of abnormal En chloroplasts containing numerous starch granules.Further analyses reveal that starch synthesis during the day and starch degradation at night are greatly suppressed in the mutant anthers,leading to carbon starvation and low energy status,as evidenced by low trehalose-6-phosphate content and a reduced ATP/AMP ratio.The energy sensor and inducer of autophagy,SnRK1,was activated to induce early and excessive autophagy,premature PCD,and metabolic reprogramming in tapetal cells,finally arresting the elongation and development of mutant anthers.Taken together,our results not only show that ZmMs33 is required for normal structure and function of En chloroplasts but also reveal that starch metabolism and photosynthetic activities of En chloroplasts at different developmental stages are essential for normal anther development.These findings provide novel insights for understanding how lipid biosynthesis in the tapetum,the structure and function of En chloroplasts,and energy and substance metabolism are coordinated to maintain maize anther development. | Taotao Zhu Ziwen Li Xueli An Yan Long Xiaofeng Xue Ke Xie Biao Ma Danfeng Zhang Yijian Guan Canfang Niu Zhenying Dong Quancan Hou Lina Zhao Suowei Wu Jinping Li Weiwei Jin Xiangyuan Wan | 2020 | Molecular Plant2020，13，11： | 9 |
| 10 | Mercury levels and estimated total daily intakes for children and adults from an electronic waste recycling area in Taizhou, China: Key role of rice and fish consumption显示文摘In order to assess the potential health risks of Hg pollution, total mercury(T–Hg) and methyl mercury(Me Hg) concentrations were determined in air, dust, surface soil, crops, poultry,fish and human hair samples from an electronic waste(e-waste) recycling area in Taizhou,China. High concentrations of T–Hg and Me Hg were found in these multiple matrices, and the mean concentration was 30.7 ng/m3 of T–Hg for atmosphere samples, 3.1 μg/g of T–Hg for soil, 37.6 μg/g of T–Hg for dust, 20.3 ng/g of Me Hg for rice and 178.1 ng/g of Me Hg for fish,suggesting that the e-waste recycling facility was a significant source of Hg. The inorganic Hg(I–Hg) levels(0.84 μg/g) in hair samples of e-waste workers were much higher than that in the reference samples. Pearson's correlation coefficients showed that strong positive correlations(p < 0.01) between hair I–Hg and time staying in industrial area(r = 0.81) and between Me Hg and fish consumption frequency(r = 0.91), imply that workers were mainly exposed to Hg vapor through long-time inhalation of contaminated air and dust, while other population mainly exposed to Me Hg through high-frequency fish consumption. The estimated daily intakes of Hg showed that dietary intake was the major Hg exposure source,and Hg intakes from rice and fish were significantly higher than from any other foods. The estimated total daily intakes(TDIs) of Me Hg for both children(696.8 ng/(kg·day)) and adults(381.3 ng/(kg·day)) greatly exceeded the dietary reference dose(Rf D) of 230 ng/(kg·day),implying greater health risk for humans from Hg exposures around e-waste recycling facilities. | Wei Tang Jinping Cheng Wenchang Zhao Wenhua Wang | 2015 | Journal of Environmental Sciences2015，27，8： | 8 |
| 11 | The fundamental characteristics of current in the Bering Strait and the Chukchi Sea from July to September 2003显示文摘The characteristics of current in the Bering Strait and the Chukchi Sea are analyzed based on the two current data on the mooring stations during the Second National Arctic Research Expedition of China in 2003. The tidal currents of the principal diurnal and semidiurnal ellipses rotate clockwise in the upper layer, except for N2 , S2 , and Q1 at Sta. ST. In the Bering Strait (Sta. ST), the major semi-axis of tidal current constituent M2 is 2.9 cm/s in the upper layer, which is much smaller than that of semi-monthly oscillation (11.8 cm/s); and the mean current flows northwestward at the amplitude of about 20 cm/s and varies a little with depth. During the cruise, the current has significant semi-monthly oscillation at the two mooring stations. The spectra analyses of the air pressure gradient and the wind stress show that there are the semi-monthly oscillations in these two data series. The near-inertial current, approximately 4 cm/s, presents almost the same magnitude of the principal tidal currents in the Bering Strait. | LI Lei DU Ling ZHAO Jinping ZUO Juncheng LI Peiliang | 2005 | Acta Oceanologica Sinica2005，24，6： | 7 |
| 12 | Seasonal and inter-annual variations of the primary types of the Arctic sea-ice drifting patterns显示文摘Monthly mean sea ice motion vectors and monthly mean sea level pressure (SLP) for the period of 1979 -2006 are investigated to understand the spatial and temporal changes of Arctic sea-ice drift. According to the distinct differences in monthly mean ice velocity field as well as in the distribution of SLP, there are four primary types in the Arctic Ocean: Beaufort Gyre+Transpolar Drift, Anticyclonic Drift, Cyclonic Drift and Double Gyre Drift. These four types account for 81% of the total, and reveal distinct seasonal variations. The Cyclonic Drift with a large-scale anticlockwise ice motion pattern trends to prevail in summer while the Anticyclonic Drift with an opposite pattern trends to prevail in winter and spring. The prevailing seasons for the Beaufort Gyre+Transpolar Drift are spring and autumn, while the Double Gyre Drift trends to prevail in winter, especially in Feb- ruary. The annual occurring times of the Anticyclonic Drift and the Cyclonic Drift are closely correlated with the yearly mean Arc- tic Oscillation (AO) index, with a correlation coefficient of -0.54 and 0.54 (both significant with the confident level of 99%), re- spectively. When the AO index stays in a high positive (negative) condition, the sea-ice motion in the Arctic Ocean demonstrates a more anticlockwise (clockwise) drifting pattern as a whole. When the AO index stays in a neutral condition, the sea-ice motion becomes much more complicated and more transitional types trend to take place. | WANG Xiaoyu ZHAO Jinping | 2012 | Advances in Polar Science2012，23，2： | 7 |
| 13 | A novel wheat NAC transcription factor,Ta NAC_(30), negatively regulates resistance of wheat to stripe rust显示文摘NAC transcription factors are widespread in the plant kingdom and play essential roles in the transcriptional regulation of defense responses. In this study, we isolated a novel NAC transcription factor gene, Ta NAC_(30),from a c DNA library constructed from wheat(Triticum aestivum) plants inoculated with the stripe rust pathogen Puccinia striiformis f. sp. tritici(Pst). Ta NAC_(30) contains a typical NAM domain and localizes to the nucleus. Yeast one-hybrid assays revealed that Ta NAC_(30) exhibits transcriptional activity and that its C-terminus is necessary for the activation of transcription. Expression of Ta NAC_(30) increased when host plants were infected with a virulent race(CYR_(31)) of the rust fungus Pst. Silencing of Ta NAC_(30) byvirus-induced gene silencing inhibited colonization of the virulent Pst isolate CYR_(31). Moreover, detailed histological analyses showed that silencing of Ta NAC_(30) enhanced resistance to Pst by inducing a significant increase in the accumulation of H_2O_2. Finally, we overexpressed Ta NAC_(30) in fission yeast and determined that cell viability was severely reduced in Ta NAC_(30)-transformed cells grown on medium containing H_2O_2. These results suggest that Ta NAC_(30) negatively regulates plant resistance in a compatible wheat-Pst interaction. | Bing Wang Jinping Wei Na Song Ning Wang Jing Zhao Zhensheng Kang | 2018 | Journal of Integrative Plant Biology2018，60，5： | 6 |
| 14 | Research on Autonomous Orbit Determination of Navigation Satellite Based on Crosslink Range and Orientation Parameters Constraining显示文摘Autonomous navigation of navigation satellite is di scussed. The method of auto-orbit determination using the crosslink range and o rientation parameters constraining is put forward. On the basis of the analysis of its feasibility, some useful conclusions are given. | CAI Zhiwu ZHAO Dongming CHEN Jinping JIAO Wenhai | 2006 | Geo-Spatial Information Science2006，9，1： | 6 |
| 15 | The Physical Significance of the Synthetic Running Correlation Coefficient and Its Applications in Oceanic and Atmospheric Studies显示文摘In order to study the temporal variations of correlations between two time series,a running correlation coefficient(RCC)could be used.An RCC is calculated for a given time window,and the window is then moved sequentially through time.The current calculation method for RCCs is based on the general definition of the Pearson product-moment correlation coefficient,calculated with the data within the time window,which we call the local running correlation coefficient(LRCC).The LRCC is calculated via the two anomalies corresponding to the two local means,meanwhile,the local means also vary.It is cleared up that the LRCC reflects only the correlation between the two anomalies within the time window but fails to exhibit the contributions of the two varying means.To address this problem,two unchanged means obtained from all available data are adopted to calculate an RCC,which is called the synthetic running correlation coefficient(SRCC).When the anomaly variations are dominant,the two RCCs are similar.However,when the variations of the means are dominant,the difference between the two RCCs becomes obvious.The SRCC reflects the correlations of both the anomaly variations and the variations of the means.Therefore,the SRCCs from different time points are intercomparable.A criterion for the superiority of the RCC algorithm is that the average value of the RCC should be close to the global correlation coefficient calculated using all data.The SRCC always meets this criterion,while the LRCC sometimes fails.Therefore,the SRCC is better than the LRCC for running correlations.We suggest using the SRCC to calculate the RCCs. | ZHAO Jinping CAO Yong WANG Xin | 2018 | Journal of Ocean University of China2018，17，3： | 5 |
| 16 | Surface Heat Budget and Solar Radiation Allocation at a Melt Pond During Summer in the Central Arctic Ocean显示文摘The heat budget of a melt pond surface and the solar radiation allocation at the melt pond are studied using the 2010 Chinese National Arctic Research Expedition data collected in the central Arctic. Temperature at a melt pond surface is proportional to the air temperature above it. However, the linear relationship between the two varies, depending on whether the air temperature is higher or lower than 0℃. The melt pond surface temperature is strongly influenced by the air temperature when the latter is lower than 0℃. Both net longwave radiation and turbulent heat flux can cause energy loss in a melt pond, but the loss by the latter is larger than that by the former. The turbulent heat flux is more than twice the net longwave radiation when the air temperature is lower than 0℃. More than 50% of the radiation energy entering the pond surface is absorbed by pond water. Very thin ice sheet on the pond surface(black ice) appears when the air temperature is lower than 0℃; on the other hand, only a small percentage(5.5%) of net longwave in the solar radiation is absorbed by such a thin ice sheet. | ZHANG Shugang ZHAO Jinping SHI Jiuxin JIAO Yutian | 2014 | Journal of Ocean University of China2014，13，1： | 5 |
| 17 | A double-halocline structure in the Canada Basin of the Arctic Ocean显示文摘A year-round halocline is a particular hydrographic structure in the upper Arctic Ocean. On the basis of an analysis of the hydrographic data collected in the Arctic Ocean, it is found that a double-halocline structure exists in the upper layer of the southern Canada Basin, which is absolutely different from the Cold Halocline Layer (CHL) in the Eurasian Basin. The Pacific-origin water is the primary factor in the formation of the double-halocline structure. The upper halocline lies between the summer modification and the winter modification of the Pacific-origin water while the lower halocline results from the Pacific-origin water overlying upon the Atlantic-origin water. Both haloclines are all the year-round although seasonal and interannual variations have been detected in the historical data. | SHI Jiuxin ZHAO Jinping LI Shujiang CAO Yong QU Ping | 2005 | Acta Oceanologica Sinica2005，24，6： | 5 |
| 18 | Pharmacokinetics of H002, a novel S1PR_1 modulator, and its metabolites in rat blood using liquid chromatography–tandem mass spectrometry显示文摘A rapid and sensitive liquid chromatography–tandem mass spectrometry(LC–MS/MS) method was developed and validated for the simultaneous determination of H002 and its phosphorylated metabolite, H002-P and hydroxylated metabolite H002-M, in rat blood. H001, an analogue of H002, was used as the internal standard.Blood samples were prepared by simple protein precipitation. The analytes and internal standard were separated on a Zorbax SB-C18 column with a gradient mobile phase consisting of methanol and water containing 0.1% formic acid at a flow rate of 0.2 mL /min with an operating temperature of 20 1C. The detection was performed on a triple quadrupole tandem mass spectrometer with positive electrospray ionization in multiple-reaction monitoring mode.Linear detection responses were obtained from 0.2–100 ng/mL for H002 and H002-M, while 0.5–100 ng/mL for H002-P. The intra- and inter-day precision(RSD%) was within 11.76%, with the accuracy(RE%) ranging from –9.84% to 9.12%. The analytes were shown to be stable during sample storage, preparation and analytic procedures.The method was applied to determine the pharmacokinetics of H002 in rats, and a preliminary study showed that the pharmacokinetics of H002 correlated with its biological effect on peripheral blood lymphocytes. | Jiaqi Mi Manman Zhao Shu Yang Shuang Yang Jing Jin Xiaojian Wang Qiong Xiao Jinping Hu Yan Li | 2016 | Acta Pharmaceutica Sinica B2016，6，6： | 5 |
| 19 | A facile and general approach for the synthesis of fluorescent silica nanoparticles doped with inert dyes显示文摘A general and facile approach was developed for the synthesis of almost monodisperse fluorescent silica nanoparticles (NPs) doped with inert dyes, which are organic fluorophores that are strongly fluorescent but are hydrophobic or lack a covalent binding group. The prepared NPs were mesoporous and the dye molecules were encapsulated in the pores via hydrophobic interaction with the CTAB template. The NPs were stable and highly fluorescent in aqueous solution, and have potential applications in bioanalysis and fluorescence encoding. | MU Xue WU ChuanLiu LAI JinPing CHEN JianBin ZHENG JinSheng LI Chong ZHAO YiBing | 2011 | Chinese Science Bulletin2011，56，31： | 5 |
| 20 | Summer water temperature structures and their interannual variation in the upper Canada Basin显示文摘Conductivity, temperature and depth (CTD) data from 1993-2010 are used to study water temperature in the upper Canada Basin. There are four kinds of water temperature structures: The remains of the winter convective mixed layer, the near-surface temperature maximum (NSTM), the wind-driven mixed layer, and the advected water under sea ice. The NSTM mainly appears within the conductive mixed layer that forms in winter.Solar heating and surface cooling are two basic factors in the formation of the NSTM. The NSTM can also appear in undisturbed open water, as long as there is surface cooling. Water in open water areas may advect beneath the sea ice. The overlying sea ice cools the surface of the advected water, and a temperature maximum could appear similar to the NSTM. The NSTM mostly occurred at depths 10-30 m because of its deepening and strengthening during summer, with highest frequency at 20 m. Two clear stages of interannual variation are identified. Before 2003, most NSTMs were observed in marginal ice zones and open waters, so temperature maxima were usually warmer than 0 . After 2004, most NSTMs occurred in ice-covered areas, with much colder temperature maxima.Average depths of the temperature maxima in most years were about 20 m, except for about 16 m in 2007,which was related to the extreme minimum of ice cover. Average temperatures were around -0.8 to -1.1 , but increased to around -0.5 in 2004, 2007 and 2009, corresponding to reduced sea ice. As a no-ice summer in the Arctic is expected, the NSTM will be warmer with sea ice decline. Most energy absorbed by seawater has been transported to sea ice and the atmosphere. The heat near the NSTM is only the remains of total absorption, and the energy stored in the NSTM is not considerable. However, the NSTM is an important sign of the increasing absorption of solar energy in seawater. | ZHAO Jinping CAO Yong | 2011 | Advances in Polar Science2011，22，4： | 4 |
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