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| 1 | Multi-analyte analysis of cytokines that predict outcomes in patients with hepatocellular carcinoma treated with radiotherapy显示文摘AIM To analyze cytokine levels and to identify their association with outcome in patients with hepatocellular carcinoma(HCC) treated with radiotherapy(RT). METHODS Patients with HCC who were treated with RT were eligible for this prospective study. Blood samples were collected before and after RT, and serum cytokine levels including interleukin(IL)-1, IL-6, IL-8, IL-10, IL-12, and tumor necrosis factor-α were analyzed. RESULTS Between 2008 and 2009, 51 patients were enrolled in this study. Baseline IL-6 level was high in patients with a history of pre-RT treatment. Median survival was 13.9 mo with alpha-fetoprotein(AFP) as a significant factor(P = 0.020). Median failure-free survival(FFS) for infield, outfield-intrahepatic and extrahepatic failures were 23.3, 11.5 and 12.0 mo, respectively. Sex and baseline IL-6 level were associated with infield FFS, and baseline IL-10 level was correlated with outfield-intrahepatic FFS. For extrahepatic FFS, AFP was significant(P =0.034). Patients with a baseline IL-6 level of ≥ 9.7 pg/m L showed worse infield FFS(P = 0.005), and this significance was observed only in treatment-non-na?ve patients(P = 0.022). CONCLUSION In addition to AFP, cytokines seem useful in predicting infield and outfield-intrahepatic failure. Serum cytokines could be useful biomarkers for predicting RT outcome in HCC. | Hyejung Cha Eun Jung Lee Jinsil Seong | 2017 | World Journal of Gastroenterology2017，23，11： | 3 |
| 2 | Applicability of BCLC stage for prognostic stratification in comparison with other staging systems: single centre experience from long‐term clinical outcomes of 1717 treatment‐na?ve patients with hepatocellular carcinoma显示文摘 | Beom Kyung Kim Seung Up Kim Jun Yong Park Do Young Kim Sang Hoon Ahn Mi Sung Park Eun Hye Kim Jinsil Seong Do Youn Lee Kwang‐Hyub Han | 2012 | Liver Int2012，，7： | 2 |
| 3 | Stereotactic body radiation therapy and radiofrequency ablation in patients with hepatocellular carcinoma:not a rival but a partner for the cure显示文摘Among various liver-directed local treatments for hepatocellular carcinoma(HCC),stereotactic body radiation therapy(SBRT),which delivers a highly ablative dose to the tumor,has increasingly been adopted in clinical practice and demonstrates favorable outcomes.Given the low priority of SBRT in the current treatment guidelines(1,2),there have been several series comparing SBRT and other local treatments,such as radiofrequency ablation(RFA),transarterial chemoembolization. | Nalee Kim Jinsil Seong | 2022 | Hepatobiliary Surgery and Nutrition2022，11，5： | 2 |
| 4 | Dose - response relationship in radiotherapy for hepatocellular carcinoma显示文摘 | Hee CP Jinsil S Kwang HH | 2002 | Int J Radia Oncol Biol Phys2002，54，： | 1 |
| 5 | Combination treatment of localized concurrent chemoradiation therapy and transarterial chemoembolization in locally advanced hepatocellular carcinoma with intrahepatic metastasis显示文摘 | Mi Sung Park Seung Up Kim Jun Yong Park Do Young Kim Sang Hoon Ahn Kwang Hyub Han Chae Yoon Chon Jinsil Seong | 2013 | Cancer Chemotherapy and Pharmacology2013，，1： | 1 |
| 6 | Radiotherapeutic Parameters Predictive of Liver Complications Induced by Liver Tumor Radiotherapy显示文摘 | Ik Jae Lee Jinsil Seong Su Jung Shim Kwang Hyub Han | 2009 | International Journal of Radiation Oncology, Biology, Physics2009，，1： | 1 |
| 7 | Dose - response relationship in local radiotherapy for hepatocellular carcinoma 显示文摘 | Jinsil S Kwang HH | 2002 | Int J Radiat Oncol Biol Phys2002，54，1： | 1 |
| 8 | Dose - response relationship in radiotherapy for hepatocellular carcinoma显示文摘 | Hee CP Jinsil S Kwang HH | 2002 | Int J Radia Oncol Biol Phys2002，54，1： | 1 |
| 9 | Dose-response relation-ship in local radiotherapy for hepatocellular carcinoma显示文摘 | Hee CP Jinsil S Kwang HH | | 0，，01： | 1 |
| 10 | Dose -response relationshep in local radiotherapy for hepatocellular carcinoma显示文摘 | Jinsil S K Wang HH | 2002 | Int J Radiat Oncol Biol Phys2002，54，1： | 1 |
| 11 | Dose-response relationship in local radiotherapy for hepatocellular carcinoma 显示文摘 | HEE CP JINSIL S KWANG HH | 2002 | Int J Radiat Oncol Biol phys2002，54，： | 1 |
| 12 | Dose-response rela-tionshipin radiotherapy forhepatocellular carcinoma显示文摘 | Hee CP JinsilS Kwang HH | 2002 | Int J Radiaoncon Biol Phys2002，54，1： | 1 |
| 13 | Dose-response relationship in local radiotherapy for hepatocellular carcinoma显示文摘 | Hee Cp Jinsil S K Wang H H | 2002 | Int J Radiat Oncol Biol Phys2002，54，1： | 1 |
| 14 | Dose-response relationship in local radiotherapy for hepatocellular carcinoma显示文摘 | HEE C P JINSIL S KWANG H H | 2002 | Int J Radiat Oncol Biol Phys2002，54，1： | 1 |
| 15 | The role of postoperative radiotherapy in hepatocellular carcinoma显示文摘Surgery is the standard treatment for early-stage hepatocellular carcinoma(HCC).However,the application of surgery is frequently expanded in real-world practice beyond the early stage,involving even advanced HCC associated with vascular invasion(1).Two important issues arise when the scope of surgery in HCC is expanded:achieving R0 resection and preserving sufficient future remnant liver volume.These two issues often contradict each other in HCC with large size or vascular invasion because surgeons try to secure sufficient future remnant liver to avoid post-resection liver failure,thereby leading to narrow-margin hepatectomy. | Joongyo Lee Jinsil Seong | 2022 | Hepatobiliary Surgery and Nutrition2022，11，1： | 1 |
| 16 | A comparative study of volumetric analysis, histopathologic downstaging, and tumor regression grade in evaluating tumor response in locally advanced rectal cancer following preoperative chemoradiation显示文摘 | Nam Kyu Kim Seung Hyuk Baik Byung Soh Min Hong Ryull Pyo Yun Jung Choi Hogeun Kim Jinsil Seong Ki Chang Keum Sun Young Rha Hyun Cheol Chung | 2007 | International Journal of Radiation Oncology Biology Physics2007，，1： | 1 |
| 17 | Symmetry-controlled colloidal nanocrystals: Nonhydmlytic chemi- cal synthesis and shape determining parameters 显示文摘 | Youngwook Jun JaeHyun Lee Jinsil Choi | 2005 | J Phys C hem B2005，109，14： | 1 |
| 18 | p53, BCL-2, and Ki-67 Expression According to Tumor Response After Concurrent Chemoradiotherapy for Advanced Rectal Cancer显示文摘 | Nam Kyu Kim Jae Kun Park Kang Yong Lee Woo IK Yang Seong Hyeon Yun JinSil Sung Jin Sik Min | 2001 | Annals of Surgical Oncology2001，，5： | 1 |
| 19 | Dose - response relationship in local radiotherapy for hepatocellular carcinoma显示文摘 | Hee CP Jinsil S Kwang HH | 2002 | Int J Radia Oncol Biol Phys2002，54，1： | 1 |
| 20 | Dose - response relationship in radiotherapy for hepatocellular carcinoma显示文摘 | Hee CP Jinsil S Kwang HH | 2002 | Int J Radia Oncol Biol Phys2002，54，1： | 1 |
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