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| 1 | MiR-139-5p inhibits migration and invasion of colorectal cancer by downregulating AMFR and NOTCH1显示文摘MicroRNAs (miRNAs ) 由抑制最近在 carcinogenesis 和转移在我们 non-protein-coding RNA 的角色的理解带给卓见的 posttranscriptional 施加功能。在这研究,我们在 CRC 在 colorectal 癌症(CRC ) 和它的潜在的临床的应用程序描述了函数和 miR-139-5p 的分子的机制。我们发现 miR-139-5p 是显著地, CRC 与邻近的 noncancerous 纸巾(NCT ) 相比取样的在 73.8% 的 downregulated,和减少的 miR-139-5p 与穷人被联系预后。功能的分析证明 miR-139-5p 的那个宫外的表达式在 vivo 在 vitro 和转移压制了 CRC 房间移植和侵略。机械学的调查表明 miR-139-5p 由指向 AMFR 和 NOTCH1 压制 CRC 房间侵略和转移。二基因 phenocopied 击倒 CRC 上的 miR-139-5p 的禁止的效果转移。而且,二基因的蛋白质层次与 NCT 相比是在 CRC 样品的 upregulated,并且相反地与 miR-139-5p 表示相关。增加的 NOTCH1 蛋白质表示与 CRC 病人的差的预后被相关。一起,我们的数据显示 miR-139-5p 为 CRC 是潜在的肿瘤 suppressor 和预示的因素,并且指向 miR-139-5p 可以镇压 CRC 的转移并且改善幸存。 | Mingxu Song Yuan Yin Jiwei Zhang Binbin Zhang Zehua Bian Chao Quan Leyuan Zhou Yaling Hu Qifeng Wang Shujuan Ni Bojian Fei Weili Wang Xiang Du Dong Hua Zhaohui Huang | 2014 | Protein & Cell2014，5，11： | 14 |
| 2 | MicroRNA-638 inhibits cell proliferation by targeting phospholipase D1 in human gastric carcinoma显示文摘MicroRNAs (miRNAs ) 是经常是玩的小非编码的 RNA 的一种类型在 carcinogenesis 的重要角色,而是 miRNAs 的 carcinogenic 机制仍然是不清楚的。这研究将在癌(GC ) 调查功能和 miR-638 的机制。在 GC 和 miR-638 的 DNA 拷贝数字的 miR-638 的表示被即时 PCR 检测。房间增长上的 miR-638 的效果被数 kit-8 试金测量。不同试金,包括生物信息学算法(TargetScan 并且人权保护) ,酶报告试金并且西方的弄污,被用来在 GC 识别 miR-638 的目标基因。在临床的 CRC 纸巾的 miR-638 目标基因的表示被 immunohistochemical 试金也验证。从这研究,我们发现 miR-638 与相应 noncancerous 纸巾(NCT ) 相比是在 GC 纸巾的 downregulated,并且 miR-638 的 DNA 拷贝数字比 NCT 在 GC 是更低的,它可以在 GC 导致 miR-638 的相应 downregulation。miR-638 的宫外的表示在 vitro 禁止了 GC 细胞生长。随后,我们鉴别 PLD1 是在 GC,和 silencing PLD1 表示 phenocopied 的 miR-638 的目标基因 GC 房间增长上的 miR-638 的禁止的效果。而且,我们观察到 PLD1 是在在预言的 GC 的 PLD1 的 GC 纸巾,和高表示的 overexpressed 差的全面幸存。在摘要,我们表明 miR-638 通过禁止 PLD1 在 GC 作为肿瘤 suppressor 工作。 | Jiwei Zhang Zehua Bian Jialiang Zhou Mingxu Song Zhihui Liu Yuyang Feng Li Zhe Binbin Zhang Yuan Yin Zhaohui Huang | 2015 | Protein & Cell2015，6，9： | 8 |
| 3 | Operation characteristics of AMS-02 loop heat pipe with bypass valve显示文摘Loop heat pipes (LHPs) were designed for the alpha magnetic spectrometer (AMS-02) to dissipate heat from the cryocoolers. A bypass valve is applied to the LHP to keep the cryocooler temperature above its limit ( 20°C) in cold environment. Extensive experiments were performed on operation characteristics of LHPs with the bypass valve for AMS-02 during thermal vacuum and thermal balance (TVTB) test. We found that the bypass valve can start up successfully in cold environment. With the bypass valve, the evaporator temperature is stable and can meet the requirement of the cryocooler. We analyzed three operating modes of the bypass valve. Set point temperature and regulation temperature shifts were observed and their relations with the bypass valve temperature were given. | WANG NaiHua Joseph BURGER LUO Feng CUI Zheng XIN GongMin DU WenJing SONG JiWei CHEN Yan CHENG Lin | 2011 | Science China(Technological Sciences)2011，54，7： | 6 |
| 4 | Design and test of flexible chassis automatic tracking steering system显示文摘In order to develop an innovative omnidirectional non-homonymic flexible chassis(FC),the four-wheel steering control method of FC was designed by a new concept called off-centered steering(OCS)and the automatic tracking steering system was analyzed.Novelty of this wheel concept lies in the non-conventional positioning of the steering axis and wheel axis.Additionally,the steering axis of steerable wheel was motorized with an on/off electrometrical brake to overcome a hyper-motorization issue inherent to the wheel’s geometrical properties and hold the steering position.Based on the off-centered steering characteristics of FC,the Wheatstone bridge was applied in the steering control system.The bridge resistances are used to track target steering angles and the actual steering angle,respectively.The output voltage of the bridge is exploited to adjust the wheel’s speed so that steering and automatic tracking could be achieved.Experiments at different speeds,loadings,and target steering angles were conducted.Results showed that the chassis can indeed be controlled independently and its steering range is from-90°to 90°,which indicated the automatic tracking steering system was effective.The electromagnetic lock(EL)can significantly improve the stability of the chassis and reduce the vibration.Loading has no significant effect on the accuracy of the steering angle and the time it takes to complete steering tasks.The time taken to complete a forward steering task showed a linear relationship with the required angles,but was independent of rotation speed;for backward steering,time was related to both target angles and rotation speed.The results presented in this research may provide a reference for the steering control strategies of the four-wheel individual drive and four-wheel(4WID/4WIS)vehicle in the future. | Song Shujie Li Yining Qu Jiwei Zhou Wei Guo Kangquan | 2017 | International Journal of Agricultural and Biological Engineering2017，10，5： | 4 |
| 5 | Sea Experiments of the Underway Conductivity-Temperature-Depth Prototype Made in China显示文摘A new instrument for upper ocean survey, namely the UCTD (Underway Conductivity-Temperature-Depth), which combines some of the advantages of other underway instruments, is introduced in this paper. The Introduction section presents a description of the construction and function of the UCTD, and the experiments conducted in the South China Sea on board the R/V Dong Fang Hong 2 in July 2007 and August 2008. The UCTD system, with pressure and temperature sensors in the probe, is con- veniently portable, cost-effective and environment-friendly. It is hopefully suitable for future cruises. An intercomparison based on regressing with the experiment temperature data from both SeaBird plus911 CTD and the UCTD showed that the standard deviation is 0.88℃ and the correlation coefficient is 0.96, achieving the goals set for the current oceanography uses. In the hydrodynamic experiments, the descending velocities and depths were calculated for different ship speeds. A pulling test was designed with a tensiometer to measure the magnitude of the pull. The maximal tension of the line was found to be 66.2 kg, which is far lower than the bearing limit of the Hollow Spectra line. Finally, some improvement suggestions are put forward for future experiments and production. | SONG Xiangzhou LI Hui LIN Xiaopei CHEN Xueen GUO Xinshun TIAN Jiwei | 2009 | Journal of Ocean University of China2009，8，4： | 4 |
| 6 | Theoretical analysis of a method for segmented heat exchanger design显示文摘In the process of the design of heat exchangers,it is difficult to establish the factors governing the optimal points of the design objective functions due to the contradictions and uncertainties of the design objectives.The variation of fluid properties is one of the main factors causing this type of uncertainty.Conventional design methods have not completely solved these problems.In the present work,based on the logarithmic mean temperature difference,a new heat exchanger design method(called the segmented design method) is proposed which takes into account the variation of fluid properties with respect to the temperature.In this method,the whole heat exchanger is first divided into several segments.Then by applying the principle of the conservation of energy and taking into account the initial conditions as well as the connecting conditions of the adjacent segments,the inlet and outlet temperatures of each segment are determined.Finally,the application of the logarithmic mean temperature difference method on each segment defines the heat transfer area. | SONG JiWei XU MingTian CHENG Lin | 2011 | Chinese Science Bulletin2011，56，20： | 2 |
| 7 | Experimental study and analysis of a novel multi-media plate heat exchanger显示文摘The experimental study and analysis of a novel multi-media plate heat exchanger were performed in this paper.This novel multi-media plate heat exchanger was self-developed during the process of the investigation and design of the alpha magnetic spectrometer(AMS) thermal system.The plate of this kind of novel plate heat exchanger is formed by discontinuous structure wave consisting of convex sphere and concave sphere,its heat transfer performance is better than that of the BR1 chevron plate heat exchanger,and its resistance characteristics are superior to those of the normally used 60-degree plate heat exchanger.Furthermore,the mechanism analysis of heat transfer enhancement shows that the spherical wave structure can reduce the local field synergy angle,so as to improve the field synergy degree of velocity vector and temperature gradient vector. | SONG JiWei WANG Fei CHENG Lin | 2012 | Science China(Technological Sciences)2012，55，8： | 2 |
| 8 | Identifying and annotating human bifunctional RNAs reveals their versatile functions显示文摘Bifunctional RNAs that possess both protein-coding and noncoding functional properties were less explored and poorly understood. Here we systematically explored the characteristics and functions of such human bifunctional RNAs by integrating tandem mass spectrometry and RNA-seq data. We first constructed a pipeline to identify and annotate bifunctional RNAs,leading to the characterization of 132 high-confidence bifunctional RNAs. Our analyses indicate that bifunctional RNAs may be involved in human embryonic development and can be functional in diverse tissues. Moreover, bifunctional RNAs could interact with multiple miRNAs and RNA-binding proteins to exert their corresponding roles. Bifunctional RNAs may also function as competing endogenous RNAs to regulate the expression of many genes by competing for common targeting miRNAs. Finally,somatic mutations of diverse carcinomas may generate harmful effect on corresponding bifunctional RNAs. Collectively,our study not only provides the pipeline for identifying and annotating bifunctional RNAs but also reveals their important gene-regulatory functions. | Geng Chen Juan Yang Jiwei Chen Yunjie Song Ruifang Cao Tieliu Shi Leming Shi | 2016 | Science China(Life Sciences)2016，59，10： | 1 |
| 9 | Light-in duced change of charge transfer band in one europium doped aluminosilicate glass 显示文摘 | Baojuan Sun Hongwei Song Jiwei Wang | 2003 | Chemical Physics Letters2003，368，： | 1 |
| 10 | Correction to:MiR-139-5p inhibits migration and invasion of colorectal cancer by downregulating AMFR and NOTCH1显示文摘CORRECTION TO:PROTEIN CELL(2014)5(11):851-861 http://gffzzd3cc09b8251d45dfoonqu5qunq5ub6c9o.ffgz.tsg.suse.edu.cn/10.1007/S13238-014-0093-5 In the original publication the display of Fig.1 is in correct.The correct Fig.1 is available in this correction. | Mingxu Song Yuan Yin Jiwei Zhang Binbin Zhang Zehua Bian Chao Quan Leyuan Zhou Yaiing Hu Qifeng Wang Shujuan Ni Bojian Fei Weiii Wang Xiang Du Dong Hua Zhaohui Huang | 2021 | Protein & Cell2021，12，8： | 1 |
| 11 | Evidence of ceased programmed cell death in metaphloem sieve elements in the developing caryopsis of Triticum aestivum L.显示文摘 | Likai Wang Zhuqing Zhou Xuefang Song Jiwei Li Xiangyi Deng Fangzhu Mei | 2008 | Protoplasma (-)2008，，14： | 1 |
| 12 | Light-in duced luminescent enhancement and structural change in cubic nanocrystalline Y203 :Tb显示文摘 | Wang Jiwei Song Hongwei Sun Baojuan | 2003 | Chemical Physics Let ters2003，379，56： | 1 |
| 13 | Fatigue-less relaxor ferroelectric thin films with high energy storage density via defect engineer显示文摘Thin film capacitors with excellent energy storage performances,thermal stability and fatigue endurance are strongly desired in modern electrical and electronic industry.Herein,we design and prepare lead-free0.7Sr_(0.7)Bi_(0.2)TiO_(3)-0.3BiFeO_(3)-x%Mn(x=0,0.5,1.5,2,3)thin films via sol-gel method.Mn ions of divalent valence combine with oxygen vacancies,forming defect complex,which results in marked decline in leakage current and obvious enhancement in breakdown strength.A high energy storage density~47.6 J cm^(-3)and good efficiency~65.68%are simultaneously achieved in 2%Mn doped 0.7Sr_(0.7)Bi_(0.2)TiO_(3)-0.3 BiFeO_(3)thin film capacitor.Moreover,the 2%Mn-doped thin film exhibits excellent thermal stability in wide operating temperature range(35–115℃)and strong fatigue endurance behaviors after 108 cycles.The above results demonstrate that 2%Mn-doped 0.7Sr_(0.7)Bi_(0.2)TiO_(3)-0.3 BiFeO_(3)thin film capacitor with superior energy storage performances is a potential candidate for electrostatic energy storage. | Baijie Song Shuanghao Wu Hao Yan Kun Zhu Liuxue Xu Bo Shen Jiwei Zhai | 2021 | Journal of Materials Science & Technology2021，，18： | 0 |
| 14 | Overview of the LAMOST survey in the first decade显示文摘The Large Sky Area Multi-Object Fiber Spectroscopic Telescope(LAMOST),also known as the Guoshoujing Telescope,is a major national scientific facility for astronomical research located in Xinglong,China.Beginning with a pilot survey in 2011,LAMOST has been surveying the night sky for more than 10 years.The LAMOST survey covers various objects in the Universe,from normal stars to peculiar ones. | Hongliang Yan Haining Li Song Wang Weikai Zong Haibo Yuan Maosheng Xiang Yang Huang Jiwei Xie Subo Dong Hailong Yuan Shaolan Bi Yaoquan Chu Xiangqun Cui Licai Deng Jianning Fu Zhanwen Han Jinliang Hou Guoping Li Chao Liu Jifeng Liu Xiaowei Liu Ali Luo Jianrong Shi Xuebing Wu Haotong Zhang Gang Zhao Yongheng Zhao | 2022 | The Innovation2022，3，2： | 0 |
| 15 | Evaluation of freezing state of sandstone using ultrasonic time-frequency characteristics显示文摘Common problems in engineering projects that involve artificial ground freezing of soil or rock include inadequate thickness,strength and continuity of artificial frozen walls.It is difficult to evaluate the freezing state using only a few thermometer holes at fixed positions or with other existing approaches.Here we report a novel experimental design that investigates changes in ultrasonic properties(received waveform,wave velocity V_(p),wave amplitude,frequency spectrum,centroid frequency f_(c),kurtosis of the frequency spectrum KFS,and quality factor Q)measured during upward freezing,compared with those during uniform freezing,in order to determine the freezing state in 150 mm cubic blocks of Ardingly sandstone.Water content,porosity and density were estimated during upward freezing to ascertain water migration and changes of porosity and density at different stages.The period of receiving the wave increased substantially and coda waves changed from loose to compact during both upward and uniform freezing.The trend of increasing V_(p) can be divided into three stages during uniform freezing.During upward freezing,V_(p) increased more or less uniformly.The frequency spectrum could be used as a convenient and rapid method to identify different freezing states of sandstone(unfrozen,upward frozen,and uniformly frozen).The continuous changes in reflection coefficient r_(φ),refraction coefficient t_(φ) and acoustic impedance field are the major reason for larger reflection and refraction during upward freezing compared with uniform freezing.Wave velocity V_(p),wave amplitude A_(h),centroid frequency f_(c) and quality factor Q were adopted as ultrasonic parameters to evaluate quantitatively the temperature T of uniformly frozen sandstone,and their application within a radar chart is recommended.Determination of V_(p) provides a convenient method to evaluate the freezing state and calculate the cryofront height and frozen section thickness of upward frozen sandstone,with accuracies of 73.37%-99.23%. | Jiwei Zhang Julian Murton Tim Cane Vikram Maji Lili Sui Shujie Liu Song Zhang | 2023 | Journal of Rock Mechanics and Geotechnical Engineering2023，15，3： | 0 |
| 16 | Interpreting the biochemical specificity of mouse spinal cord by confocal raman microspectral imaging显示文摘Interpreting the biochemical specifcity of spinal cord tissue is the essential requirement for underst.anding the biochemical mechanisms during spinal-cord-related pathological course.In this work,a longitudinal study was implemented to reveal a precise linkage betwoen the spectral features and the molecular composition in er vivo mouse spinal cord tissue by microspectral Raman imaging.It was testified that lipid-rich white matter could be distinguished from gray matter not only by the lipid Raman peaks at 1064,1300,1445 and 1660 cm^(-1),but also by protein(1250 and 1328 cm^(-1))and saccharides(913 and 1137 cm^(-1))distributions.K-means cluster analysis was further applied to visualize the morphological basis of spinal cord tissue by chemical components and their dist ribution patterns.T wo-dimensional chemical images were then generated to visualize the contrast between two different tissue types by integrating the intensitics of the featured Raman bands.All the obtained results ilustrated the biochemical characteristics of spinal cord tssue,as well as some specific substance variances bet ween different tssue types,which formed a solid basis for the molecular investigation of spinal cord pathologi cal alterations. | Yuze Gong Zhuowen Liang Yaning Yin Jiwei Song Xueyu Hu Kaige Wang Qingli He Zhe Wang Jintao Bai Shuang Wang | 2017 | Journal of Innovative Optical Health Sciences2017，，5： | 0 |
| 17 | Partial oxidation of methane by photocatalysis显示文摘Methane chemistry is one of the“Holy Grails of catalysis”.It is highly desirable but challenge to transform methane into value-added chemicals,because of its high C-H bonding energy(435 kJ/mol),lack ofπbonding or unpaired electrons.Currently,commercial methane conversion is usually carried out in harsh conditions with enormous energy input.Photocatalytic partial oxidation of methane to liquid oxygenates(PPOMO)is a future-oriented technology towards realizing high efficiency and high selectivity under mild conditions.The selection of oxidant is crucial to the PPOMO performance.Hence,attentions are paid to the research progress of PPOMO with various oxidants(O_(2),H_(2)O,H_(2)O_(2)and other oxidants).Moreover,the activation of the selected oxidants is also highly emphasized.Meanwhile,we summarized the methane activation mechanisms focusing on the C-H bond that was broken mainly by·OH radical,O-specie or photogenerated hole(h+).Finally,the challenges and prospects in this subject are briefly discussed. | Zhongshan Yang Qiqi Zhang Hui Song Xin Chen Jiwei Cui Yanhui Sun Lequan Liu Jinhua Ye | 2024 | Chinese Chemical Letters2024，35，1： | 0 |
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