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| 1 | 妊娠期高血压免疫因子、肿瘤坏死因子α、血管紧张素Ⅱ1型受体自身抗体对妊娠可溶性fms样酪氨酸1和可溶性Endoglin产物的影响显示文摘最近研究发现先兆子痫中血管新生因子、可溶性fms样酪氨酸激酶(sFlt-1)和可溶性Endoglin(sEn-doglin)不平衡;然而尚不清楚它们过度分泌的启动机制。方法:长期给予怀孕大鼠肿瘤坏死因子α(tumor necrosis factor-α,TNF-α)或抗血管紧张素Ⅱ受体的自身抗体(AT1-AA),测定其循环和胎盘的sFlt-1和(或)sEndoglin以确定这些因素的免疫调节作用。 | Parrish MR Murphy SR Rutland S Wallace K Wenzel K Wallukat G Keiser S Ray LF Dechend R Martin JN Granger JP La Marca B 黄晓斌 | 2010 | 中华高血压杂志2010，18，12： | 5 |
| 2 | 术中应用荧光素钠有利于胶质母细胞瘤浸润边缘的手术切除(英文)显示文摘Objective Extent of resection is an important prognostic factor in patients undergoing surgery for glioblastoma( GBM).Recent evidence suggests that intravenously administered fluorescein sodium associates with tumor tissue,facilitating safe maximal resection of GBM. In this study,the authors evaluate the safety and utility of intraoperative fluorescein guidance for the prediction of histopathological alteration both in the contrast-enhancing( CE) regions,where this relationship has been established,and into the nonCE( NCE),diffusely infiltrated margins. Methods Thirty-two patients received fluorescein sodium( 3 mg/kg) intravenously prior to resection. Fluorescence was intraoperatively visualized using a Zeiss Pentero surgical microscope equipped with a YELLOW 560 filter.Stereotactically localized biopsy specimens were acquired from CE and NCE regions based on preoperative MRI in conjunction with neuronavigation. The fluorescence intensity of these specimens was subjectively classified in real time with subsequent quantitative image analysis,histopathological evaluation of localized biopsy specimens,and radiological volumetric assessment of the extent of resection.Results Bright fluorescence was observed in all GBMs and localized to the CE regions and portions of the NCE margins of the tumors,thus serving as a visual guide during resection. Gross-total resection( GTR) was achieved in 84% of the patients with an average resected volume of 95%,and this rate was higher among patients for whom GTR was the surgical goal( GTR achieved in 93. 1% of patients,average resected volume of 99. 7%). Intraoperative fluorescein staining correlated with histopathological alteration in both CE and NCE regions,with positive predictive values by subjective fluorescence evaluation greater than 96% in NCE regions. Conclusions Intraoperative administration of fluorescein provides an easily visualized marker for glioma pathology in both CE and NCE regions of GBM. These findingssupport the use of fluorescein as a microsurgical adjunct for guiding GBM resection to facilitate safe maximal removal. | Neira JA Ung TH Sims J Malone HR Chow DS Samanamud JL Zanazzi GJ Guo X Bowden SG Zhao B Sheth SA McKhann GM 2nd Sisti MB Canoll P D'Amico RS Bruce JN | 2016 | 中华神经外科疾病研究杂志2016，15，5： | 2 |
| 3 | Delayed Onset of traumatic extradural hematoma显示文摘 | Borovich B Braun J Guilburd JN | 1985 | J Neurosurg1985，63，1： | 1 |
| 4 | ADAMTS13 activity in thrombotic thrombocytopenic purpura-hemolytic uremia syndrome: relation to precenting features and clinical outcomes in a perspective cohort of 142 patients显示文摘 | Vesely SK George JN Lammle B | 2003 | Blood2003，102，1： | 1 |
| 5 | Place of beta 3-adrenocepors among other beta adrenoceptor subtypes in the regulation of the cardiovascular system显示文摘 | Rozec B Noireaud J Trochu JN | 2003 | Arch Mal Coeur Vaiss2003，96，9： | 1 |
| 6 | The incidence of thrombotic thromlx~ytopenic purpura- hemolytic uremic syndrome: All patients, idiopathic patients, and patients with severe ADAMTS13 deficiency 显示文摘 | Terrell DR Williams LA Vesely SK Lammle B Hovinga JA George JN | 2005 | J Thromb Haem- ost2005，3，7： | 1 |
| 7 | The spectrum of severe preeclampsia: Comparative analysis by HELLP syndrome classification 显示文摘 | Martin JN Jr Rinehart B May WL | 1999 | Am J Obstet Gyneeol1999，180，： | 1 |
| 8 | Postterm pregnancy:practice patterns of contemporary obstetricians and gynecologists显示文摘 | Cleary-Goldman J Bettes B Robinson JN | 2006 | Am J Perinatol2006，23，： | 1 |
| 9 | Enhanced peroxynitrite formation is associated with vascular aging显示文摘 | van der Loo B Labugger R Skepper JN | | 0，，12： | 1 |
| 10 | Hydroxyethyl starch (130 kD),but not crystalloid volume supportimproves microcirculation during normotensive endotoxemia显示文摘 | Hoffmann JN Vollmar B Laschke MW | | 0，，02： | 1 |
| 11 | An evaluation of the sensitivity and specificity of medical thermography for the documentation of myofascial trigger points显示文摘 | Swerdlow B Dieter JN | 1992 | Pain1992，48，2： | 1 |
| 12 | ADAMTS-13 activity in thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: Relation to presenting features and clinical outcomes in a prospective cohort of 142 patients 显示文摘 | Vesely SK George JN Rammle B | 2003 | Blood2003，102，1： | 1 |
| 13 | A controlled study of danazol for the treatment of karyotypically normal spontaneous premature ovarian failure显示文摘 | Anasti JN White B Kimzey LM | 1994 | Fertil Steril1994，62，4： | 1 |
| 14 | Gene expression profiling and genetic markers in glioblastoma survival显示文摘 | Rich JN Hans C Jones B | 2005 | Cancer Res2005，65，10： | 1 |
| 15 | Recurrent syncope and Chiari malformation显示文摘 | Guillon B Trochu JN Olindo S | 2001 | Rev Neurol (Paris)2001，157，1： | 1 |
| 16 | Microhemodynamicand cellular mechanisms of activated protein C action duringendotoxemia 显示文摘 | Hoffmann JN Vollmar B Laschke MW | 2004 | Crit Care Med2004，32，4： | 1 |
| 17 | Comparison of effects of fentanyl and remifentanil on hemodynamic response to endotracheal intuba- tion and myoclonus in elderly patients with etomidate induction 显示文摘 | Ko B J Oh JN Lee JH | 2013 | KoreanJAnesthesiol2013，64，1： | 1 |
| 18 | Lipid-binding proteins and lipoprotein lipase activity in human skeletal muscle:influence of physical activity and gender显示文摘 | Kiens B Roepstorff and Nielsen JN | 2004 | J Appl Physiol2004，97，： | 1 |
| 19 | Antibody to transforming growth factor beta reduces collagen production in injured peripheral nerve显示文摘 | Nath Rk Kwon B Mackinnon Se Jensen JN Reznik S Boutros S | 1998 | Plast Reconstr Surg1998，102，4： | 1 |
| 20 | Delayed onset of traumatic extradural hematoma显示文摘 | Borovich B Braun J Guilburd JN | 1985 | J Neurosurg1985，63，1： | 1 |
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