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| 1 | Analysis of orthopedic surgical procedures in children with cerebral palsy显示文摘BACKGROUND Orthopedic surgery in children with cerebral palsy(CP)aims to improve function and prevent deformities.Each child’s condition in CP is unique and many covariables influence surgical decision-making including a patient's age and their functional level.Little is known about the frequency of different types of orthopedic surgery in children with CP who have varied functional levels,particularly in countries from Latin America.AIM To assess the type of orthopedic surgical procedures in relation to age and gross motor function in children with CP.METHODS This retrospective study included all children with CP(n=245)treated with elective orthopedic surgery at a Uruguayan university hospital between October 2010 and May 2016 identified from a surgical database.Eighteen children(7%)were lost to follow-up due to missing medical charts.Demographics,gross motor function classification(GMFCS),and orthopedic surgeries were obtained from the medical records of 227 children.Chi-squared tests and analysis of variance were used to assess the frequency of surgery,accounting for GMFCS levels.Mean age for soft tissue vs bone surgery was compared with the independent samples t-test.RESULTS A total of 711 surgical procedures were performed between 1998 and 2016.On average,children had 3.1 surgical procedures and the mean age at first surgery was 8.0 years.There were no significant differences in age at first surgery among GMFCS levels(P=0.47).The most common procedures were lower leg soft tissue surgery(n=189,27%),hip tenotomy(n=135,19%),and hamstring tenotomy(n=104,14%).For children with GMFCS level Ⅰ,the mean number of surgeries per child[1.8(range 1-9)]differed significantly at P<0.05 in children with GMFCS levels Ⅱ[3.2(1-12)],Ⅲ[3.2(1-8)],Ⅳ[3.3(1-13)],and Ⅴ[3.6(1-11)].Within Ⅱ,Ⅲ,Ⅳ,and Ⅴ,there was no significant difference in mean number of surgeries per child when comparing across the groups.The proportion of soft tissue surgery vs bone surgery was higher in GMFCS levels Ⅰ-Ⅲ(80%-85%)compared to levels IV(68%)and V(55%)(P<0.05).CONCLUSION The frequency of surgical procedures per child did not increase with higher GMFCS level after level Ⅰ.However,the proportion of bone surgery was higher in GMFCS levels Ⅳ-Ⅴ compared to Ⅰ-Ⅲ. | Ignacio Rehbein Viviana Teske Ignacio Pagano Alejandro Cúneo María Elena Pérez Johan von Heideken | 2020 | World Journal of Orthopedics2020，11，4： | 2 |
| 2 | Mature results of PulmonArt:Involved-field 3D radiotherapy(RT)and docetaxel/ cisplatin chemotherapy(CT)in a randomised phase 2 study comparing concurrent CT-RT followed by consolidation CT, with induction CT followed by concurrent CT-RT in patients(pts)with stage III non-small cell lung cancer(NSCLC): B5-06 显示文摘 | van Meerbeeck JP Felipe C Johan V | 2007 | J Thorac Oncol2007，2，8： | 1 |
| 3 | Efficient solar cellsbased on an easily accessible diketopyrrologyrrole polymer显示文摘 | Johan C Bijleveld Veronique | 2010 | Adv Mater2010，22，： | 1 |
| 4 | Lensed fiber-array assembly with individu- al fiber fine positioning in the submicrometer range 显示文摘 | Johan H C van Zantvoort Simon G L Plukker Erwin C A Dekkers | 2006 | IEEE Selected Topics in Quantum Electronics2006，12，05： | 1 |
| 5 | Early‐onset gastric carcinomas display molecular characteristics distinct from gastric carcinomas occurring at a later age显示文摘 | RalphCarvalho Anya NAMilne Bastiaan Pvan Rees EricCaspers LuísCirnes CéuFigueiredo G Johan AOfferhaus Marian AJWeterman | 2004 | J Pathol2004，，1： | 1 |
| 6 | Inhalational nickel earbonyl poisoning in waste processing workers 显示文摘 | SEET R C JOHAN A TEO C E | 2005 | Chest2005，128，1： | 1 |
| 7 | Torque and drag in directional wells-prediction and measurement 显示文摘 | JOHAN SICK C A FRIESEN D B RAPIER DAW- SON | 1983 | IADC/SPE 11380(1983)1983，，： | 1 |
| 8 | Insulin: a wonder drug in the critically ill显示文摘 | Johan Groeneveld A B Beishuizen A Visser F C | 2002 | Crit Care2002，6，2： | 1 |
| 9 | Comparative proteomics ofindustrial lager yeast reveals differential expression of Thecerevisiae and non-cerevisiae parts of their genomes显示文摘 | Robert C Johan P John S G | 2007 | Proteomics2007，7，22： | 1 |
| 10 | Bone-targeted radium-223 in symptomatic, hormone-refractory prostate cancer: a randomised, multicentre, placebo-controlled phase II study显示文摘 | Sten Nilsson Lars Franzén Christopher Parker Christopher Tyrrell René Blom Jan Tennvall Bo Lennern?s Ulf Petersson Dag C Johannessen Michael Sokal Katharine Pigott Jeffrey Yachnin Michael Garkavij Peter Strang Johan Harmenberg Bj?rg Bolstad ?yvind S Brula | 2007 | Lancet Oncology2007，，7： | 1 |
| 11 | A career counseling program for dentists: effects on burnout显示文摘 | Ronald C Gorter Michiel A.J Eijkman Johan Hoogstraten | 2001 | Patient Education and Counseling2001，，1： | 1 |
| 12 | The impact of charging plug-in hybrid electric vehicles on a residential distribution grid显示文摘 | KRISTIEN C N EDWIN H JOHAN D | 2010 | IEEE Trans on Power Systems2010，25，1： | 1 |
| 13 | DNA methylation and diet in cancer显示文摘 | Johanning G L Heimburger D C Piyathilake C J | 2002 | J Nutr2002，132，12： | 1 |
| 14 | Oxygen reduction on nafion-coated thin-film palladium electrodes显示文摘 | Erikson H Kasikov A Johans C | 2011 | J Electroanal Chem2011，652，1： | 1 |
| 15 | The impact of charging plug-in hybrid electric vehicles on a residential distribution grid显示文摘 | KRISTIEN C EDWIN H JOHAN D | 2010 | IEEE Trans on Power Systems2010，25，1： | 1 |
| 16 | Methylenetetrahydrofolate reductase (MTHFR) polymorphism increases the risk of cervical intraepithelial neoplasia显示文摘 | Piyathilake C J Macaluso M Johanning G | 2000 | Anticancer Res2000，20，3： | 1 |
| 17 | Influence of ligand structure on the stability and oxidation of copper nanoparticles显示文摘 | Kanninen P Johans C Merta J | 2008 | J Colloid Interface Sci2008，318，1： | 1 |
| 18 | The impact of charging plug-in hybrid electric vehicles on a residential distribution grid 显示文摘 | Kristien C Edwin H Johan D | 2010 | IEEE Trans on Power Systems2010，25，1： | 1 |
| 19 | Pore size determination in modified micro- and mesoporous materials. Pitfalls and limitations in gas adsorption data analysis显示文摘 | Johan C Groen Louk A.A Peffer Javier Pérez-Ram??rez | 2003 | Microporous and Mesoporous Materials2003，，1： | 1 |
| 20 | Zinc partitioning between glass and silicate phases in historical and modern lead-zinc metallurgical slags from the Pribram district,Czech Republic显示文摘 | ETTLER V JOHAN Z TOURAY J C JELINEK E | 2000 | Comptes Rendus de I'Académie des Sciences Paris:Série Ⅱ2000，，： | 1 |
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