|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Correlation and prognostic significance of beta-galactoside alpha-2,6-sialyltransferase and serum monosialylated alpha-fetoprotein in hepatocellular carcinoma显示文摘AIM: To investigate the correlation between tissue ST6Gal I and serum msAFP in HCC patients, and to investigate their prognostic significance.METHODS: Preoperative sera,paired tumorous and non-tumorous tissues were collected from 19 consecutive patients who had undergone surgical resection of HCC.ST6Gal T activities in the tissues were measured by an in vitro microsomal enzyme activity assay. The percentages of tumor-specific msAFP in the sera were also estimated by an isoelectric focusing-immunoblotting assay.RESULTS: The tumor ST6Gal I activity was negatively correlated with serum msAFP percentage (r = -0.53,P = 0.019). Both decreased tumor ST6Gal I activity andincreased serum msAFP percentage were associatedwith poor tumor cell differentiation. Univariate analyses showed that both decreased tumor ST6Gal T activity (P = 0.028), increased serum msAFP percentage (P = 0.034) and poor tumor cell differentiation (P = 0.031)were associated with shorter overall survival. Multivariate analysis using the Cox regression model showed that the preoperative serum msAFP percentage (P = 0.022)and tumor cell differentiation status (P = 0.048) were independent prognostic indicators for patient overall survival.CONCLUSION: Our results indicate that the presence of msAFP in blood circulation is associated with a decreased activity of ST6Gal I activity in HCC. Both tissue ST6Gal I and serum msAFP are potential prognostic markers for patients with operable HCC. | Terence CW Poon Clarissa HS Chiu Paul BS Lai Tony SK Mok Benny Zee Anthony TC Chan Joseph JY Sung Philip J Johnson | 2005 | World Journal of Gastroenterology2005，11，42： | 4 |
| 2 | CT angiography with volume rendering for quantifying vascular stenoses: in vitro validation of accuracy 显示文摘 | Kuszyk BS Heath DG Johnson PT Eng J Fishman EK | 1999 | MR Am J Roentgenol1999，173，2： | 1 |
| 3 | The cytokines IL-3 and GM CSF regulate the transcriptional activity of retinoic acid receptors in different in vitro models of myeloid differentiation 显示文摘 | Johnson BS Mueller L Si J | 2002 | Blood2002，99，3： | 1 |
| 4 | Purification and characterization of glutamatedecarboxylase from cowpea显示文摘 | Johnson BS Singh NK Cherry JH | 1997 | Phytochemistry1997，46，1： | 1 |
| 5 | Periodontal diseases 显示文摘 | Pihlstrom BL Miehalowicz BS Johnson NW | 2005 | Lancet2005，366，18： | 1 |
| 6 | Treatment of adolescent idiopathic scoliosis using Texas Scottish Rite Hospital instrumentation显示文摘 | Herring JA Johnson CE | 1994 | Spine1994，19，14： | 1 |
| 7 | Interaction of cardiotonic thiadiazinone derivatives with cardiac troponin C显示文摘 | Pan BS Johnson RG | 1996 | J Biol Chem1996，271，2： | 1 |
| 8 | Periodontal diseases显示文摘 | Pihlstrom BL Michalowicz BS Johnson NW | 2005 | Lancet2005，366，9499： | 1 |
| 9 | CT angiography with volume rendering for quantifying vascular stenoses: in vitro valida- tion of accuracy显示文摘 | Kuszyk BS Heath DG Johnson PT | 1999 | Am J Roentgenol1999，173，2： | 1 |
| 10 | Periodontal diseases 显示文摘 | Pihlstrom BL Michalowicz BS Johnson NW | 2005 | Lancet2005，366，9499： | 1 |
| 11 | Renal artery stenosis:CT angiography-comparison of real-time volume-rendering and maximum intensity projection algorithms显示文摘 | Halpern EJ Kuszyk BS | 1999 | Radiology1999，211，2： | 1 |
| 12 | Periodontal disea- ses显示文摘 | Pihlstrom BL Miehalowicz BS Johnson NW | 2005 | The Lancet2005，366，9499： | 1 |
| 13 | Foot bone marrow edema after a,10-wk transition to minimalist running shoes显示文摘 | Ridge ST Johnson AW Mitchell UH Hunter I Robinson E Rich BS | | 0，，： | 1 |
| 14 | Pityrosporum folliculitis显示文摘 | Potter BS Burgoon CE Johnson WC | 1973 | Acta Dermatol1973，107，： | 1 |
| 15 | CT angiography with volume rending:advantages and applications in splanchnic vascular imaging显示文摘 | Johnson PT Heath DG Kuszyk BS | 1996 | Radiology1996，200，3： | 1 |
| 16 | CT angiography with volume rendering for quantifying vascular stenoses:in vitro validation of accuracy显示文摘 | Kuszyk BS Heath DG Johnson PT | | 0，，2： | 1 |
| 17 | Periodontal diseases 显示文摘 | Pihlstrom BL Michalowicz BS Johnson NW | 2005 | Lancet2005，366，9499： | 1 |
| 18 | Periodontal diseas- es 显示文摘 | Pihlstrom BL Michalowicz BS Johnson NW | 2005 | Lancet2005，366，9499： | 1 |
| 19 | Metoprolol metabolism via cyto- chrome P4502D6 in ethnic populations 显示文摘 | Johnson JA Burlew BS | 1996 | Drug Metab Dispos1996，24，3： | 1 |
| 20 | The 5 R's of becoming a psychiatric nurse practi- tioner, Rationale, readying, roles, rules and reality显示文摘 | Johnson BS | 1998 | Journal of Psycbosocial Nursing1998，36，9： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员