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| 1 | Phytochemical and anti-bacterial activity of epidermal glands extract of Christella parasitica (L.) H. Lev.显示文摘Objective:To study the morphology,biochemistry and bioactivity of the epidermal glands of the glandular morphotype of Christella parasitica(C.parasitica)(L.) H.Lev.Methods: Morphological studies on epidermal glands were earned out by using light microscope and scanning electron microscope.To prepare the extract,the shade-dried fronds of glandular morphotype were soaked in acetone.For antibacterial studies paper disc method was followed by using various pathogenic bacteria.Results:Detailed micromorphological,phytochemical and bioactivity studies on a medicinal fern C.parasitica(L.) H.Lev.showed its inlraspecific variation in antibacterial activity.The presence or absence of the epidermal glands was the key factor for antibacterial activity in the morphovariants of this species.The epidermal glands were orange-coloured,stalked and elongated ones of about 84.2μm×45μm,and distributed on the undersurface of cosla,coslules and veins in croziers,young and mature leaves.Frequency of glands varied from 15/cm on costa in mature leaves to 140/cm on costules in croziers.The acetone extract of the glands showed antibacterial activities and also toxic effect against mosquito larvae and tadpoles of frog.Preliminary phytochemical analysis and HPLC studies of the gland extract showed the presence of various kinds of terpenoids,alkaloids,tannins,saponins and flavonoids in it.Conclusions:The present study shows that epidermal glands of the glandular morphotype of C. parasitica(L.) H.Lev.have several bioactive compounds and such rare moiphovariant should be conserved in nature.The next step is to isolate the pure compounds and to screen the bioactivity of individual compounds of the epidermal glands. | Paul Raj K Irudayaraj V Johnson M Patric Raja D | 2011 | Asian Pacific Journal of Tropical Biomedicine2011,1,1: | 14 |
| 2 | Antibacterial activity of leaves and inter-nodal callus extracts of Mentha arvensis L显示文摘Objective:To determine the anti-bacterial efficacy of chloroform,ethanol,ethyl acetate and water extracts of inter-nodal and leaves derived calli extracts from Mentha arvensis(M.arvensis) against Salmonella typhi(S.typhi),Streptococcus pyogenes(S.pyogenes),Proteus vulgaris(P. vulgaris) and Bacillus subtilis(B.subtilis).Methods:The inter-nodal and leaves segments of M.arvensis were cut into 0.5-0.7 cm in length and cultured on Murashige and Skoog solid medium supplemented with 3%sucrose,gelled with 0.7%agar and different concentration of 2,4-Dichlorophenoxyacetie acid(2,4-D) either alone or in combinations.The preliminary phytochemical screening was performed by Brindha et al method.Antibacterial efficacy was performed by disc diffusion method and incubated for 24 h at 37℃.Results:Maximum percentage of callus formation(inter-nodal segments 84.3±0.78;leaves segments 93.8±1.27) was obtained on Murashige and Skoog’s basal medium supplemented with 3%sucrose and 1.5 mg/L of 2,4-D.The ethanol extracts of leaves derived calli showed the maximum bio-efficacy than other solvents.The leaves and stem derived calli extracts on Proteus sp.showed that the plants can be used in the treatment of urinary tract infection associated with Proteus sp.Through the bacterial efficacy studies,it is confirmed that the in vitro raised calli tissue was more effective compared to in vivo tissue.Conclusions:The bio-efficacy study confirmed that the calli mediated tissues showed the maximum zone of inhibition.The present study paved a protocol to establish high potential cell lines by in vitro culture. | Johnson M Wesely EG Kavitha MS Uma V | 2011 | Asian Pacific Journal of Tropical Medicine2011,4,3: | 9 |
| 3 | 抗菌蜂蜜预防腹膜透析相关感染:一项随机对照试验显示文摘背景 目前缺少指导预防腹膜透析相关感染策略的研究证据。抗菌蜂蜜作为一种新型、廉价、有效的局部预防性使用的药物,不会诱导细菌耐药。因此,我们评估,对鼻内定植金黄色葡萄球菌的患者,与同时进行腹膜管外出口部位常规护理加上鼻内莫匹罗星去定植的方法相比,腹膜管外出口部位每日使用蜂蜜,是否会延迟首次出现腹膜透析相关感染的时间。 | Johnson D W Badve S V Pascoe E M 陈玉华 | 2014 | 中国感染控制杂志2014,13,2: | 7 |
| 4 | Disruption of sphingolipid homeostasis by myrioein, a myeotoxin, reduces thymie and splenic T-lymphocyte populations显示文摘 | Johnson V J He Q Osuchowski M F | 2004 | Toxicology2004,201,13: | 1 |
| 5 | Arctic decadal and interdecadal variability显示文摘 | Polyakov I V Johnson M A | 2000 | Geophys Res Lett2000,27,24: | 1 |
| 6 | Evaluation of Refolding Conditions for a Human Recombinant Fusion Cytokine Protein,Promegapoietin1a显示文摘 | BOYLE D M JOHNSON G V HEEREN R A | 2008 | Biotechnol Appl Biochem2008,49,: | 1 |
| 7 | When callings are calling: Crafting work and leisure in pursuit of unanswered occu- pational callings显示文摘 | Berg J M Orant A M and Johnson V | 2010 | Organization Science2010,21,5: | 1 |
| 8 | Mathematical modelling of residue allelopathy:the effects of intrinsic and extrinsic factors显示文摘 | M An I R Johnson J V Lovett | 2002 | Plant and Soil2002,,246: | 1 |
| 9 | Population pharmacokinetic -pharmacodynamic modeling of haloperi- dol in patients with schizophrenia using positive and neg- ative syndrome rating scale 显示文摘 | Pilla Reddy V Kozieiska M Johnson M | 2013 | J Clin Psychopharmacol2013,33,6: | 1 |
| 10 | Vaccines4Kids : assessing the impact of text message reminders on immunization rates ininfants 显示文摘 | Niederhauser V Johnson M Tavakoli A S | 2015 | Vaccine2015,33,26: | 1 |
| 11 | Job Strain, Work Place Social Support, and Cardiovascular Disease: A Cross -sectional Study of a Random Sample of the Swedish Working Population显示文摘 | Johnson J V Hall E M | 1988 | American Journal of Public Health1988,78,: | 1 |
| 12 | Osteopontin a molecule for all seasons显示文摘 | Mazzali M Kipari T Ophascharoensuk V Wesson J A Johnson R Hughes J | 2002 | QJM2002,95,: | 1 |
| 13 | Determination of the Cephalosporin Antibiotic Cephradine in Human Plasma by High-PeHormance Liquid Chromatography with Ultraviolet Detection 显示文摘 | Johnson V M Allanson J P Causon R C | 2000 | J Chromatogr B Biomed Sci Appl2000,740,1: | 1 |
| 14 | Preexposure antiretrovi- ral prophylaxis attitudes in high-risk Boston area men who report hav- ing sex with men:limited konwledge and experience but potential forincreased utilization after education显示文摘 | Mimiaga M J Case P Johnson C V | 2009 | J Acquir Immune Defic Syndr2009,50,1: | 1 |
| 15 | When callings are calling: Crafting work and leisure in pursuit of unanswered occu- pational callings显示文摘 | Berg J M Grant A M and Johnson V | 2010 | Organization Science2010,21,5: | 1 |
| 16 | 1993 Biological Mathematical response to allelochemicals and its interpretation显示文摘 | An M Johnson I R Lovett modeling of allelopathy J V | 1993 | Journal of Chemical Ecology1993,19,: | 1 |
| 17 | Matrix metalloproteinases in tumor invasion显示文摘 | Johnson N Ahonen M Kahari V M | 2000 | Cell Mol Life Sci2000,57,1: | 1 |
| 18 | Nanofabrication with step and flash imprint lithography显示文摘 | Stewart M D Johnson S C Sreenivasan S V | | 0,,04: | 1 |
| 19 | Evaluation of the extent of ruminal urease inhibition by sarsaponin and sarsaponin fractions显示文摘 | Ellenberger M A Rumpler W V Johnson D E | | 0,,1: | 1 |
| 20 | The major genetic determinants of HIV-1control affect HLA class I peptide presentation显示文摘 | International HIV Controllers Study Pereyra F Jia X McLaren P J Telenti A de Bakker P I Walker B D Ripke S Brumme C J Pulit S L Carrington M Kadie C M Carlson J M Heckerman D Graham R R Plenge R M Deeks S G Gianniny L Crawford G Sullivan J Gonzalez E Davies L Camargo A Moore JM Beattie N Gupta S Crenshaw A Burtt N P Guiducci C Gupta N Gao X Qi Y Yuki Y Piechocka-Trocha A Cutrell E Rosenberg R Moss K L Lemay P O'Leary J Schaefer T Verma P Toth I Block B Baker B Rothchild A Lian J Proudfoot J Alvino D M Vine S Addo M M Allen T M Altfeld M Henn M R Le Gall S Streeck H Haas D W Kuritzkes D R Robbins G K Shafer R W Gulick R M Shikuma C M Haubrich R Riddler S Sax P E Daar E S Ribaudo H J Agan B Agarwal S Ahern R L Allen B L Altidor S Altschuler E L Ambardar S Anastos K Anderson B Anderson V Andrady U Antoniskis D Bangsberg D Barbaro D Barrie W Bartczak J Barton S Basden P Basgoz N Bazner S Bellos N C Benson A M Berger J Bernard N F Bernard A M Birch C Bodner S J Bolan R K Boudreaux E T Bradley M Braun J F Brndjar J E Brown S J Brown K Brown S T Burack J Bush LM Cafaro V Campbell O Campbell J Carlson R H Carmichael J K Casey K K Cavacuiti C Celestin G Chambers S T Chez N Chirch L M Cimoch P J Cohen D Cohn LE Conway B Cooper D A Cornelson B Cox D T Cristofano M V Cuchural G Jr Czartoski J L Dahman J M Daly J S Davis B T Davis K Davod S M DeJesus E Dietz C A Dunham E Dunn M E Ellerin T B Eron J J Fangman J J Farel C E Ferlazzo H Fidler S Fleenor-Ford A Frankel R Freedberg K A French N K Fuchs JD Fuller J D Gaberman J Gallant J E Gandhi R T Garcia E Garmon D Gathe J C Jr Gaultier C R Gebre W Gilman F D Gilson I Goepfert P A Gottlieb M S Goulston C Groger R K Gurley T D Haber S Hardwicke R Hardy W D Harrigan P R Hawkins T N Heath S Hecht F M Henry W K Hladek M Hoffman R P Horton J M Hsu R K Huhn G D Hunt P Hupert M J Illeman M L Jaeger H Jellinger R M John M Johnson J A Johnson K L Johnson H Johnson K Joly J Jordan W C Kauffman C A Khanlou H Killian R K Kim A Y Kim D D Kinder C A Kirchner J T Kogelman L Kojic E M Korthuis P T Kurisu W Kwon D S LaMar M Lampiris H Lanzafame M Lederman M M Lee D M Lee J M Lee M J Lee E T Lemoine J Levy J A Llibre J M Liguori M A Little S J Liu A Y Lopez A J Loutfy M R Loy D Mohammed D Y Man A Mansour M K Marconi V C Markowitz M Marques R Martin J N Martin H L Jr Mayer K H McElrath M J McGhee T A McGovern B H McGowan K McIntyre D Mcleod GX Menezes P Mesa G Metroka CE Meyer-Olson D Miller A O Montgomery K Mounzer K C Nagami E H Nagin I Nahass R G Nelson M O Nielsen C Norene D L O'Connor D H Ojikutu B O Okulicz J Oladehin O O Oldfield E C Olender S A Ostrowski M Owen WF Jr Pae E Parsonnet J Pavlatos A M Perlmutter A M Pierce M N Pincus J M Pisani L Price L J Proia L Prokesch R C Pujet H C Ramgopal M Rathod A Rausch M Ravishankar J Rhame F S Richards C S Richman D D Rodes B Rodriguez M Rose R C 3rd Rosenberg E S Rosenthal D Ross P E Rubin D S Rumbaugh E Saenz L Salvaggio M R Sanchez WC Sanjana V M Santiago S Schmidt W Schuitemaker H Sestak P M Shalit P Shay W Shirvani V N Silebi V I Sizemore J M Jr Skolnik P R Sokol-Anderson M Sosman J M Stabile P Stapleton J T Starrett S Stein F Stellbrink H J Sterman FL Stone V E Stone D R Tambussi G Taplitz R A Tedaldi E M Telenti A Theisen W Torres R Tosiello L Tremblay C Tribble M A Trinh P D Tsao A Ueda P Vaccaro A Valadas E Vanig T J Vecino I Vega V M Veikley W Wade B H Walworth C Wanidworanun C Ward D J Warner D A Weber R D Webster D Weis S Wheeler D A White D J Wilkins E Winston A Wlodaver C G van't Wout A Wright D P Yang O O Yurdin D L Zabukovic B W Zachary K C Zeeman B Zhao M | 2010 | Science2010,330,6010: | 1 |