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| 1 | 冠状动脉内影像学临床应用专家共识(第一部分):对冠状动脉介入治疗的指导与优化显示文摘欧洲心血管介入协会(EAPCI)专家组系统总结了血管内超声(IVUS)和光学相干断层成像(OCT)这两种血管内影像学检查临床应用指征的现有证据,提供了关于IVUS和OCT指导经皮冠状动脉介入治疗(PCI)的应用价值,并明确了最可能从腔内影像学指导的介入治疗中获得临床收益的患者或病变类型,同时详细论述了PCI前如何使用IVUS或OCT优化支架尺寸(支架长度和直径)和手术策略的选择。此外,专家推荐对支架失败(支架内再狭窄或支架内血栓形成)的患者应常规进行冠状动脉内影像学检查,并首选OCT。最后,重点论述了IVUS和OCT在指导PCI和评估支架失败两个方面的优势和局限性,并对未来需要深入研究的领域进行了展望。 | Lorenz Raber Gary S Mintz Konstantinos C Koskinas Thomas W Johnson Niels R Holm Yoshinubo Onuma Maria D Radu Michael Joner Bo Yu Haibo Jia Nicolas Meneveau Jose M.de la Torre Hemandez Javier Escaned Jonathan Hill Francesco Prati Antonio Colombo Carlo di Mario Evelyn Regar Davide Capodanno William Wijns Robert A Byme Giulio Guagliumi | 2019 | 中华心血管病杂志2019，47，1： | 17 |
| 2 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 3 | 扁桃体鳞癌中HPV感染与EGFR、VEGF表达的相关性研究显示文摘目的:研究扁桃体鳞癌(squamous cell carcinomas of the tonsil tonsillar,SCCs)中人乳头瘤病毒(human papillomavirus,HPV)感染与血管内皮生长因子(vascular endothelial growth factor,VEGF)和表皮生长因子受体(epidermal growth factor,EGFR)表达的关系,探讨HPV与EGFR和VEGF在扁桃体鳞癌发生中的交互效应。方法:采用多重实时荧光定量聚合酶链反应(multiplex real-time polymerase chain reaction,MT-PCR)检测85例扁桃体鳞癌HPV DNA及型别,通过HPV DNA分析进行HPV感染状况的测定;同时采用半定量免疫组化检测HPV(+)组和HPV(-)组中VEGF、EGFR蛋白表达情况。结果:扁桃体鳞癌中HPV感染率为49.4%(42/85),HPV-16型占所有感染者的比例为90.5%(38/42),明显高于其他型别;HPV(+)组EGFR蛋白表达明显低于HPV(-)组(P值均<0.01);HPV(+)组与HPV(-)组VEGF蛋白表达无明显差异;此外,VEGF表达与EGFR、患者的年龄、性别、TNM分期、组织学分级均无明显相关性。结论:HPV感染与扁桃体鳞癌的发生存在相关性,HPV相关的扁桃体鳞癌中,HPV基因可能通过改变EGFR表达致癌,为HPV致癌机理进一步研究提供一个新的视角,具有重要的理论意义。 | 费继敏 Timothy A Dobbins Deanna Jones C Soon Lee Christine Loo Jonathan Clark Barbara Rose | 2015 | 现代肿瘤医学2015，23，4： | 3 |
| 4 | 用心脏的磁性的回声成像部分 1: 的心肌症的调查普通显型显示文摘 Cardiac magnetic resonance imaging(CMRI) has emerged as a useful tertiary imaging tool in the investigation of patients suspected of many different types of cardiomyopathies,CMRI sequences are now of a sufficiently robust quality to enable high spatial and temporal resolution image acquisition.This has led to CMRI becoming an effective non-invasive imaging gold standard for many cardiomyopathies.In this 2-part review,we outline the typical sequences used to image cardiomyopathy,and present the imaging spectrum of cardiomyopathy.Part 1 focuses on the current classification of cardiomyopathy,basic CMRI sequences used in evaluating cardiomyopathy and the imaging spectrum of common phenotypes. | Shaunagh McDermott Ailbhe C O’Neill Carole A Ridge Jonathan D Dodd | 2012 | World Journal of Cardiology2012，4，4： | 2 |
| 5 | Treatment of relapsing autoimmune pancreatitis with immunomodulators and rituximab: the Mayo Clinic experience显示文摘 | Phil A Hart Mark D Topazian Thomas E Witzig Jonathan E Clain Ferga C Gleeson Robin R Klebig Michael J Levy Randall K Pearson Bret T Petersen Thomas C Smyrk Aravind Sugumar Naoki Takahashi Santhi S Vege Suresh T Chari | 2013 | Gut2013，，11： | 2 |
| 6 | Treatment of relapsing autoimmune pancreatitis with immunomodulators and rituximab: the Mayo Clinic experience显示文摘 | Phil A Hart Mark D Topazian Thomas E Witzig Jonathan E Clain Ferga C Gleeson Robin R Klebig Michael J Levy Randall K Pearson Bret T Petersen Thomas C Smyrk Aravind Sugumar Naoki Takahashi Santhi S Vege Suresh T Chari | 2013 | Gut2013，，11： | 2 |
| 7 | Guidelines for Conscious Sedation and Monitoring During Gastrointestinal Endoscopy显示文摘 | J.Patrick Waring Todd H Baron William K Hirota Jay L Goldstein Brian C Jacobson Jonathan A Leighton J.Shawn Mallery Douglas O Faigel | 2003 | Gastrointestinal Endoscopy2003，，3： | 1 |
| 8 | Incidence and predictors of glaucoma following surgery for congenital cataract in the first year of life in V ictoria, A ustralia显示文摘 | Jonathan B Ruddle Sandra E Staffieri Jonathan G Crowston Justin C Sherwin David A Mackey | 2013 | Clin Experiment Ophthalmol2013，，7： | 1 |
| 9 | An intertemporal general equilibrium model of asset prices and theory of the term struc- ture of interest rates显示文摘 | JOHN C JONATHAN E STEPHEN A | 1985 | Econometrica1985，53，2： | 1 |
| 10 | An Intertemporal General Equilibrium Model of Asset Prices显示文摘 | Cox John C Jonathan E Ingersoll Stephen A Ross | 1985 | Econometrica1985，53，： | 1 |
| 11 | NASA's evolutionary xenon thruster long-duration test results显示文摘 | Daniel A H Soulas G C Jonathan L | 2012 | Journal of Propulsion and Power2012，28，3： | 1 |
| 12 | Follicle stimula ting hormone (FSH) actives the P mitogen activated protein ki- nase pathway, inducing small heat shock protein phosphorylation and cell rounding in immature rat ovarian granulosa cells显示文摘 | Evelyn T M Joshu A C Jonathan C R J | 1998 | En docrinology1998，139，7： | 1 |
| 13 | Pectin is not pectin: A randomized trial on the effect of different physicochemical properties of dietary fiberon appetite and energy intake显示文摘 | WANDERS A J FESKENS E J M JONATHAN M C | 2014 | Physiology & Behavior2014，，128： | 1 |
| 14 | Data stream clustering: A survey显示文摘 | JONATHAN A S ELAINE R F~ RODRIGO C B | 2013 | ACM Computing Sur- veys2013，46，1： | 1 |
| 15 | An Intertemporal General Equilibrium Model of Asset Prices 显示文摘 | Cox John C Ingensoll Jonathan E Ross Stephen A | 1985 | Econometrics1985，，2： | 1 |
| 16 | Catalytic reduction of hexachlorobenzene and pentachlorobenzene by cobalt(Ⅰ) salen electrogenerated at vitreous carbon cathodes in dimethylformamide显示文摘 | Philip C Gach Jonathan A Karty Dennis G Peters | 2008 | Electroanalytical Chemistry2008，，612： | 1 |
| 17 | Photoelectrochemical determination of analysis of ascorbic acid 显示文摘 | Jonathan A C Wu M Richard G C | 1998 | Analytical Chemistry1998，70，14： | 1 |
| 18 | The im- pact of elevated water ammonia and nitrate concentrations on physiology, growth and feed intake of pikepereh ( San- der lucioperca) 显示文摘 | Edward S Jonathan A C R Tiedo V K | 2014 | Aquaculture2014，，： | 1 |
| 19 | Yield trends are insufficient to doubleglobal crop production by 2050显示文摘 | Ray Deepak K Mueller Nathaniel D West Paul C Foley Jonathan A | 2013 | Plos One2013，8，66： | 1 |
| 20 | Meta-Analysis of Calcium Supplementation for the Prevention of Postmenopausal Osteoporosis显示文摘 | Beverley S George W Ann C Nicole Z Vivian R Lauren G Zulma O Joan P Jonathan A Peter T Gordon G | 2002 | Endocrine Reviews2002，23，4： | 1 |
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