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| 1 | Effect of hepatic artery embolization on liver hypertrophy response in a rabbit liver VX2tumor model显示文摘BACKGROUND:Portal vein embolization not only induces hypertrophy of the non-embolized liver,but also enhances tumor growth.The latter could be prevented by embolizing the hepatic arteries supplying the tumor-bearing liver segments.This study aimed to determine the effects of transcatheter arterial embolization(TAE)on tumor volume and liver regeneration in a rabbit VX2 tumor model.METHODS:Twenty-three rabbits underwent subcapsular tumor implantation with a VX2 tumor.Two weeks after implantation,18 rabbits were used for TAE experiments,5were for sham controls.Tumor response and liver regeneration response of the embolized cranial and non-embolized caudal liver lobes were assessed by CT volumetry,liver to body weight index,and the amount of proliferating hepatocytes.RESULTS:All super-selective arterial tumor embolization procedures were performed successfully.Despite embolization,the tumor volume increased after an initial steady state.The tumor volume after embolization was smaller than that of the sham group,but this difference was not significant.Massive necrosis of the tumor,however,was seen after embolization,without damage of the surrounding liver parenchyma.There was a significant atrophy response of the tumor bearing cranial lobe after super-selective arterial embolization of the tumor with a concomitant hypertrophy response of the non-embolized,caudal lobe.This regeneration response was confirmed histologically by a significantly higher number of proliferating hepatocytes on the Ki-67 stained slides.CONCLUSIONS:Super-selective,bland arterial coil embolization causes massive necrosis of the tumor,despite increase of volume on CT scan.Atrophy of the tumor bearing liver lobe is seen after arterial embolization of the tumor with a concomitant hypertrophy response of the non-embolized lobe,despite absence of histological damage of the tumor-surrounding liver parenchyma. | Krijn P van Lienden Lisette T Hoekstra Jessica D van Trigt Joris J Roelofs Otto M van Delden Thomas M van Gulik | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，6： | 2 |
| 2 | Glucose-sensing mechanisms in eukary-otic cells显示文摘 | Rolland F Joris W Jolian T M | 2011 | Trends in Biochemical Sciences2011，26，5： | 1 |
| 3 | Evidence for biotype-specific effectsof bovine viral diarrhea virus on biological responses in acutely infected calves显示文摘 | Joris E Douart A | 1998 | Journal of General Virology1998，79，： | 1 |
| 4 | Hem odynam ic changes during laparoscopic cholecystectomy显示文摘 | Joris J L Noirot D P Legrand M J | 1993 | Aneath Analg1993，76，5： | 1 |
| 5 | Characterizzation of the immune response of cattle against non-cytopathic and cytopathic biotype of bovin viral diarrhea显示文摘 | Douart A Joris E | 1997 | Gen Virol1997，78，： | 1 |
| 6 | Acute renal failure requiring haemodialysis after high doses percutaneous acetic acid injection for hepatocellular carcinoma显示文摘 | Van Hoof M Joris J P Horsmans Y | 1999 | Acta Gastroenterol Belg1999，62，1： | 1 |
| 7 | Molecular pathways involved in neural in vitro differentiation of marrow stromal stem cells 显示文摘 | Jori FP Napolitano MA Melone MA Cipollaro M Cascino A Altucci L | 2005 | J Cell Biochem2005，94，4： | 1 |
| 8 | Low - power, 2 x 2 silicon electro - optic switch with 110 -nm bandwidth for broadband reconfigurable optical networks 显示文摘 | JORIS V C GREEN William M ASSEFA Solomon | 2009 | Opt Express2009，17，24： | 1 |
| 9 | Shrimp white spot virus in the western hemisphere 显示文摘 | Jory D E Dixon H M | 1999 | Aquaculture1999，25，： | 1 |
| 10 | Molecular path- ways involved in neural in vitro differentiation of marrow stromal stem cells显示文摘 | Jori F P Napolitano M A Melone M A | 2005 | J Cell Biochem2005，94，4： | 1 |
| 11 | Accuracy and predictability in use of AO three-dimensionally preformed titanium mesh plates for post- traumatic orbital reconstruction: a pilot study 显示文摘 | Paolo S Armen M Joris | 2009 | Craniofac Surg2009，20，4： | 1 |
| 12 | Use of ropivacaine for peridural postoperative analgesia显示文摘 | Senard M Joris J | 2002 | Ann Fr Anesth Reanim2002，21，7： | 1 |
| 13 | Hemodynamic changes during laparoscopic cholecystectomy 显示文摘 | Joris JL Noirot DP Legrand M J | 1993 | Anesth Analg1993，76，5： | 1 |
| 14 | Metabolic and respiratory changes after cholecystectomy performed via laparotomy or laparoscopy显示文摘 | Joris J Cigarini I kgrarId M | 1992 | Br J Anaesth1992，69，： | 1 |
| 15 | Modelling soil - sweep inter- action with discrete element method 显示文摘 | Tamas K Jori I J Mouazen A M | 2013 | Soil and Tillage Re-search2013，134，： | 1 |
| 16 | Effects of intravenous patient -controlled analgesia with morphine,continuous epidural analgesia,and continuous three-in-one block on postoperative pain and knee rehabilitation after unilateral knee arthroplasty显示文摘 | Singelyn F J Deyaert M Joris D | 1998 | Anesth Analg1998，87，： | 1 |
| 17 | Advanced of the pods:enhancing precision attacks night and day显示文摘 | Writes M H Joris J L | 2002 | Jane''s International Defense Review2002，35，44： | 1 |
| 18 | Metabolic and respitatory changes after cholecystectomy performed via laparotomv or laparoscopy显示文摘 | Joris J Cigarini I Legrand M | 1992 | Br J Anaseth1992，69，4： | 1 |
| 19 | The use of pre-operative in- trathecal morphine for analgesia following coronary artery bypass surgery 显示文摘 | Roediger L Joris J Senard M | 2006 | Anaesthesia2006，61，9： | 1 |
| 20 | PrenataltestinginICSIpregnancies: incidedce of chromosomal anomalies in 1586 karyotypes and relation to sperm parameters显示文摘 | Bonduelle M VanAssche E Joris H | 2002 | Human Repred2002，17，10： | 1 |
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