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| 1 | Nat Med:靶向两分子或有助于彻底治愈白血病显示文摘科学家在癌细胞内发现两个信号蛋白能够让癌细胞抵抗化疗。研究表明阻断这两种蛋白能够增强化疗对人类白血病小鼠模型的治疗效果。相关研究结果发表在国际学术期刊NatureMedicine上。研究人员发现在治疗中阻断c-Fos和Dusp1这两个蛋白能够治愈一些受激酶驱动且抵抗治疗的白血病和实体瘤。 | Meenu Kesarwani, Zachary Kincaid, Ahmed Gomaa, Erika Huber, Sara Rohrabaugh, Zain Siddiqui, Muhammad F Bouso, Kakajan Komurov, James C Mulloy, Jose A Cancelas, H Leighton Grimes Mohammad Azam Tahir Latif Ming Xu H Leighton Grimes Mohammad Azam | 2017 | 现代生物医学进展2017，17，17： | 4 |
| 2 | Chronic overexpression of PNPLA3^sup I148M^ in mouse liver causes hepatic steatosis显示文摘 | Li John Zhong Huang Yongcheng Karaman Ruchan Ivanova Pavlina T Brown H Alex Roddy Thomas Castro-Perez Jose Cohen Jonathan C Hobbs Helen H | 2012 | EN2012，，11： | 3 |
| 3 | DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice显示文摘 | Meira Lisiane B Bugni James M Green Stephanie L Lee Chung-Wei Pang Bo Borenshtein Diana Rickman Barry H Rogers Arlin B Moroski-Erkul Catherine A McFaline Jose L Schauer David B Dedon Peter C Fox James G Samson Leona D | 2008 | Journal of Clinical Investigation2008，，7： | 2 |
| 4 | Robust Kalman filter for descriptor systems显示文摘 | Ishihara Joao Y Terra Marco H Campos Jose C T | 2006 | IEEE Trans on Automatic Control2006，51，8： | 1 |
| 5 | Optical techniques for real-time penetration monitoring for laser welding 显示文摘 | Fabfice B Adolfo C Jose M L H | 2005 | Applied Optics2005，44，19： | 1 |
| 6 | Arsenic and heavy metals innative plants at tailings impoundments in Queretaro, Mexico显示文摘 | Jose S J Alejandrina C R Jose H C | 2012 | Physicsand Chemistry of the Earth2012，3739，： | 1 |
| 7 | A method for calibration and validation subset partitioning 显示文摘 | Galvao R K H Araujo M C U Jose G E | 2005 | Talanta2005，67，4： | 1 |
| 8 | Emulsion polymerization in a loop reactor: effect of the operation conditions显示文摘 | Araujo Pedro H H Abad Carlos de la Cal Jose C | 1999 | Polymer Reaction Engineering1999，7，3： | 1 |
| 9 | Cloning, expression, and characterization ofavian reovirus guanylytransferase显示文摘 | Joseph H Jose M C Javier B | 2002 | Virology2002，296，2： | 1 |
| 10 | Cell proliferation of human fibroblasts on alumina and hydroxyapatite-based ceramics with different surface treat- ments 显示文摘 | Delfino Carina S Bressiani Jose C Bressianiana H A | 2010 | Int J Appl Ceram Techn2010，7，2： | 1 |
| 11 | Combined models for glaze ice accretion and de-icing of current-carrying electrical conductors 显示文摘 | Maurice H Christian L Josee C | 2005 | IEEE Trans onPower Delivery2005，20，2： | 1 |
| 12 | Maintenance strategy based on a multicriterion classification of equipments 显示文摘 | C G L H Felix J R C Jose | 2006 | Reliability Engineering and System Safety2006，，91： | 1 |
| 13 | The Olsen-P method as an agronomic and environmental test for predicting phosphorus release from acid soils显示文摘 | Maria D C H Jose J | 2007 | Nutrient Cycling of Agroecosystem2007，77，： | 1 |
| 14 | On-line multi-sensor registration for data fusion on airport surface显示文摘 | JESUS G H JUAN A B P JOSE R C C | 2007 | IEEE Trans on AES2007，43，1： | 1 |
| 15 | Group 6 metal oxide carbon aerogels: Their syn- thesis, characterization and catalytic activity in the skeletal isomerization of 1 butene显示文摘 | CARLOS M C JOSE F M H JOSE R U | 1999 | Appl Catal A: General1999，183，： | 1 |
| 16 | A method for calibration and validation subset partitioning显示文摘 | Galvao R K H Araujo M C U Jose G E | 2005 | Talanta2005，67，4： | 1 |
| 17 | Issues to consider, existing tools and constraints in biofuels sustainability assessments显示文摘 | Silva Lora Electo E Escobar Palacio Jose C Rocha Mateus H | 2011 | Energy2011，36，4： | 1 |
| 18 | Industrial and biotechnological applications of laccase: A review 显示文摘 | Susana R C Jose L T H | 2006 | Biotechnology Advances2006，24，： | 1 |
| 19 | Allelopathy and exotic plant invasion显示文摘 | Jose L H Ragan M C | 2003 | Plant and Soil2003，256，1： | 1 |
| 20 | Cell proliferation of human fibroblasts on alumina and hydroxyapatite-based ceramics with different surface treatments显示文摘 | Delfino Carina S Bressiani Jose C Bressianiana H A | 2010 | International Journal of Applied Ceramic Technology2010，7，2： | 1 |
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