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17篇 您的检索式：作者名="Joseph B U"

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		题名	作者	年代	出处	被引量
	1	The cell cycle inhibitor p57 (Kip2) promotes cell death via the mitochondrial apoptotic pathway显示文摘	Vlachos P Nyman U Hajji N Joseph B	2007	Cell Death Differ2007，14，8：	1
	2	The role of p73 in hematological malignancies显示文摘	Pluta A Nyman U Joseph B	2006	Leukemia2006，20，5：	1
	3	The role of p73 in hematologica malignancies 显示文摘	Pluta A Nyman U Joseph B	2006	Leukemia2006，20，：	1
	4	Phosphates in Sediments of Pamlico Estuary显示文摘	Joseph B U James K E Charles R O	1974	Environ Sci Technol1974，8，：	1
	5	The role of p73 in hematological malignancies显示文摘	Nyman U Joseph B	2006	Leukemia2006，20，5：	1
	6	Using knockout mutants to reveal the growth costs of defensive traits显示文摘	Z(U)ST T JOSEPH B SHIMIZU K K	2011	Proceedings of Royal Society B:Biological Sciences2011，278，1718：	1
	7	The role of p73 in hematological mali- gnancies显示文摘	Pluta A Nyman U Joseph B	2006	Leukemia2006，20，5：	1
	8	The role of p73 in hematological malignancies 显示文摘	Pluta A Nyman U Joseph B	2006	Leukemia2006，20，5：	1
	9	Real-world cure rates for hepatitis C virus treatments that include simeprevir and/or sofosbuvir are comparable to clinical trial results显示文摘AIM To assess the real-world effectiveness and cost of simeprevir(SMV), and/or sofosbuvir(SOF)-based therapy for chronic hepatitis C virus(HCV) infection.METHODS The real-world performance of patients treated with SMV/SOF ± ribavirin(RBV), SOF/RBV, and SOF/RBV with pegylated-interferon(PEG) were analyzed in a consecutive series of 508 patients with chronic HCV infection treated at a single academic medical center. Patients with genotypes 1 through 4 were included. Rates of sustained virological response-the absence of a detectable serum HCV RNA 12 wk after the end of treatment [sustained virological response(SVR) 12]-were calculated on an intention-to-treat basis. Costs were calculated from the payer's perspective using Medicare/Medicaid fees and Redbook Wholesale Acquisition Costs. Patient-related factors associated with SVR12 were identified using multivariable logistic regression.RESULTS SVR 12 rates were as follows: 86%(95%CI: 80%-91%)among 178 patients on SMV/SOF ± RBV; 62%(95%CI: 55%-68%) among 234 patients on SOF/RBV; and 78%(95%CI: 68%-86%) among 96 patients on SOF/PEG/RBV. Mean costs-per-SVR 12 were $174442(standard deviation: ± $18588) for SMV/SOF ± RBV; $223003(± $77946) for SOF/RBV; and $126496(± $31052) for SOF/PEG/RBV. Among patients on SMV/SOF ± RBV, SVR12 was less likely in patients previously treated with a protease inhibitor [odds ratio(OR): 0.20, 95%CI: 0.06-0.56]. Higher bilirubin(OR: 0.47, 95%CI: 0.30-0.69) reduced the likelihood of SVR12 among patients on SOF/RBV, while FIB-4 score ≥ 3.25 reduced the likelihood of SVR 12(OR: 0.18, 95%CI: 0.05-0.59) among those on SOF/PEG/RBV. CONCLUSION SVR 12 rates for SMV and/or SOF-based regimens in a diverse real-world population are comparable to those in clinical trials. Treatment failure accounts for 27% of costs.	Kian Bichoupan Neeta Tandon James F Crismale Joshua Hartman David Del Bello Neal Patel Sweta Chekuri Alyson Harty Michel Ng Keith M Sigel Meena B Bansal Priya Grewal Charissa Y Chang Jennifer Leong Gene Y Im Lawrence U Liu Joseph A Odin Nancy Bach Scott L Friedman Thomas D Schiano Ponni V Perumalswami Douglas T Dieterich Andrea D Branch	2017	World Journal of Virology2017，6，4：	1
	10	The role of p73 in hematological malignancies显示文摘	PLUTA A NYMNA U JOSEPH B	2006	Leukemia2006，20，：	1
	11	Molecular-size selective H-fl zeo- lite-encapsulated Ce-Zr/Ni-Mg catalysts for steam reforming 显示文摘	Cimenler U Joseph B Kuhn J N	2015	Applied Catalysis A General2015，505，：	1
	12	The role of p73 in hematological malignancies显示文摘	Pluta A Nyman U Joseph B	2006	Leukemia2006，20，5：	1
	13	Histone onco-modifications显示文摘	F(U)LLGRABE J KAVANAGH E JOSEPH B		0，，31：	1
	14	Changes in lipid peroxidation and free radical scavengers in kidney of hypothyroid and hyperthyroid rats显示文摘	Sawant B U Nadkarni G D Thakare U R Joseph L J Rajan M G	2003	Indian J Exp Biol2003，41，：	1
	15	The role of p73 in hematological malignancies显示文摘	PLUTA A NYMAN U JOSEPH B	2006	Leukemia2006，20，：	1
	16	TAp73alpha protects small cell lung carcinoma cells from caspase -2 induced mitochondrial medi- ated apoptotic cell death 显示文摘	Muppani N Nyman U Joseph B	2011	Oncotarget2011，2，12：	1
	17	Cell surface hydrophobicity of oral Candida dukliniensis i- solates following limited exposure to sub-therapeutic concentrations of chlorhexidine gluconate 显示文摘	ELLEPOLA A N B JOSEPH B K KHAN Z U	2013	Myco- ses2013，56，1：	1

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