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| 1 | ACS Nano:科学家利用来自尿液的生物标志物进行早期癌症筛查显示文摘日前。来自韩国蔚山国家科学技术研究所的研究人员通过研究开发出了一种新技术,该技术能够有效在尿液或血液中有效鉴别出促进癌症发生的物质,相关研究刊登于国际杂志ACS Nano上。 | Hyun-Kyung Woo Vijaya Sunkara Juhee Park Tae-Hyeong Kim Ja-Ryoung Han Chi-Ju Kim Hyun-Il Choi Yoon-Keun Kim Yoon-Kyoung Cho | 2017 | 现代生物医学进展2017，17，11： | 8 |
| 2 | Association Between Markers of Glucose Metabolism and Risk for Colorectal Adenoma显示文摘 | Sanjay Rampal Moon Hee Yang Jidong Sung Hee Jung Son Yoon-Ho Choi Jun Haeng Lee Young-Ho Kim Dong Kyung Chang Poong-Lyul Rhee Jong Chul Rhee Eliseo Guallar Juhee Cho | 2014 | Gastroenterology2014，，： | 2 |
| 3 | Changes of Quality of Life in Gastric Cancer Patients After Curative Resection: A Longitudinal Cohort Study in Korea显示文摘 | Ae Ran Kim Juhee Cho Yea-Jen Hsu Min Gew Choi Jae Hyung Noh Tae Sung Sohn Jae Moon Bae Young Ho Yun Sung Kim | 2012 | Annals of Surgery2012，，： | 1 |
| 4 | Hippocampal and cortical atrophy in amyloid-negative mild cognitive impairments: comparison with amyloid-positive mild cognitive impairment显示文摘 | Byoung Seok Ye Sang Won Seo Chi Hun Kim Seun Jeon Geon Ha Kim Young Noh Hanna Cho Cindy W. Yoon Hee Jin Kim Eun Young Jang Jeongmin Lee Jung-Hyun Kim Juhee Chin Jong Min Lee Jeong-Hun Kim Joon-kyung Seong Chang-Hun Kim Yearn Seong Choe Kyung Han Lee Duk L | 2014 | Neurobiology of Aging2014，，2： | 1 |
| 5 | Surface modification of nation membranes using atmospheric-pressure low-temperature plasmas for electrochemical applications显示文摘 | Jong Hoon Kim Juhee Sohn Jin Hoon Cho | 2008 | Plasma Processes and Polymers2008，5，4： | 1 |
| 6 | Characteristics and outcomes of chronic liver disease patients with acute deteriorated liver function by severity of underlying liver disease显示文摘AIM: To analyze characteristics and outcome of patients with acute-on-chronic liver failure(ACLF) according to the severity of underlying liver disease. METHODS: One hundred and sixty-seven adult patients with chronic liver disease and acute deteriorated liver function, defined by jaundice and coagulopathy, were analyzed. Predisposition, type of injury, response, organ failure, and survival were analyzed and compared between patients with non-cirrhosis(type A), cirrhosis(type B) and cirrhosis with previous decompensation(type C).RESULTS: The predisposition was mostly hepatitis B in type A, while it was alcoholic liver disease in typesB and C. Injury was mostly hepatic in type A, but was non-hepatic in type C. Liver failure, defined by CLIF-SOFA, was more frequent in types A and B, and circulatory failure was more frequent in type C. The 30-d overall survival rate(85.3%, 81.1% and 83.7% for types A, B and C, respectively, P = 0.31) and the 30-d transplant-free survival rate(55.9%, 65.5% and 62.5% for types A, B and C, respectively P = 0.33) were not different by ACLF subtype, but 1-year overall survival rate were different(85.3%, 71.7% and 58.7% for types A, B and C, respectively, P = 0.02).CONCLUSION: There were clear differences in predisposition, type of injury, accompanying organ failure and long-term mortality according to spectrum of chronic liver disease, implying classifying subtype according to the severity of underlying liver disease is useful for defining, clarifying and comparing ACLF. | Yun Soo Hong Dong Hyun Sinn Geum-Youn Gwak Juhee Cho Danbee Kang Yong-Han Paik Moon Seok Choi Joon Hyeok Lee Kwang Cheol Koh Seung Woon Paik | 2016 | World Journal of Gastroenterology2016，22，14： | 1 |
| 7 | Clinical Significance of Microbleeds in Subcortical Vascular Dementia显示文摘 | Sang Won Seo Byung Hwa Lee Eun-Joo Kim Juhee Chin Yoon Sun Cho Uicheul Yoon Duk L. Na | 2007 | Stroke2007，，6： | 1 |
| 8 | Prevalence and predictors of anxiety and depression among family caregivers of cancer patients: a nationwide survey of patient–family caregiver dyads in Korea显示文摘 | Boyoung Park So Young Kim Ji-Yeon Shin Robert W. Sanson-Fisher Dong Wook Shin Juhee Cho Jong-Hyock Park | 2013 | Supportive Care in Cancer2013，，10： | 1 |
| 9 | 4-methoxychalcone enhances cisplatin-induced oxidative stress and cytotoxicity by inhibiting the Nrf2/ARE-mediated defense mechanism in A549 lung cancer cells显示文摘 | Juhee Lim Sung Ho Lee Sera Cho Ik-Soo Lee Bok Yun Kang Hyun Jin Choi | 2013 | Molecules and Cells2013，，4： | 1 |
| 10 | Clinical Significance of Microbleeds in Subcortical Vascular Dementia显示文摘 | Sang Won Seo Byung Hwa Lee Eun-Joo Kim Juhee Chin Yoon Sun Cho Uicheul Yoon Duk L. Na | 2007 | Stroke2007，，6： | 1 |
| 11 | Dieckol isolated from Eisenia bicyclis extract suppresses RANKL-induced osteoclastogenesis in murine RAW 264.7 cells显示文摘Objective:To demonstrate the effect of dieckol from Eisenia bicyclis on osteoclastogenesis using RAW 264.7 cells.Methods:Murine macrophage RAW 264.7 cells were subjected to dieckol treatment,followed by treatment with receptor activator of nuclear factor kappa-B ligand(RANKL)to induce osteoclastogenesis.Tartrate-resistant acid phosphatase(TRAP)activity was examined using a TRAP activity kit.Western blotting analysis was conducted to examine the level of osteoclast-related factors,including TRAP and calcitonin receptor(CTR),transcriptional factors,including c-Fos,c-Jun,and nuclear factor of activated T cells cytoplasmic 1(NFATc1),nuclear factor kappa-B(NF-κB),extracellular signal-regulated kinase(ERK),and c-Jun N-terminal kinase(JNK).Immunofluorescence staining was conducted to examine the expression of c-Fos,c-Jun,and NFATc1.Results:Among the four phlorotannin compounds present in Eisenia bicyclis,dieckol significantly hindered osteoclast differentiation and expression of RANKL-induced TRAP and CTR.In addition,dieckol downregulated the expression levels of c-Fos,c-Jun,NFATc1,ERK,and JNK,and suppressed NF-κB signaling.Conclusions:Dieckol can suppress RANKL-induced osteoclastogenesis.Therefore,it has therapeutic potential in treating osteoclastogenesis-associated diseases. | Su-Hyeon Cho Tae-Hyung Kwon Hoibin Jeong Jin Sook Kim Song-Rae Kim Myeong Seon Jeong SeonJu Park Miri Choi Jung-Hee Woo Juhee Ahn Kil-Nam Kim | 2022 | Asian Pacific Journal of Tropical Biomedicine2022，12，6： | 0 |
| 12 | Effect of lifestyle modification on hepatocellular carcinoma incidence and mortality among patients with chronic hepatitis B显示文摘BACKGROUND Research exploring the influence of healthier lifestyle modification(LSM)on the risk of hepatocellular carcinoma(HCC)in patients with chronic hepatitis B(CHB)is limited.AIM To emulate a target trial to determine the effect of LSM on HCC incidence and mortality among patients with CHB by large-scale population-based observational data.METHODS Among the patients with CHB enrolled in the Korean National Health Insurance Service between January 1,2009,and December 31,2017,those aged≥20 years who drank alcohol,smoked cigarettes,and were sedentary were analyzed.Exposure included at least one LSM,including alcohol abstinence,smoking cessation,and regular exercise.The primary outcome was HCC development,and the secondary outcome was liver-related mortality.We used 2:1 propensity score matching to account for covariates.RESULTS With 48766 patients in the LSM group and 103560 in the control group,the adjusted hazard ratio(HR)for incident HCC and liver-related mortality was 0.92[95%confidence interval(CI):0.87-0.96]and 0.92(95%CI:0.86-0.99)in the LSM group,respectively,compared with the control group.Among the LSM group,the adjusted HR(95%CI)for incident HCC was 0.84(0.76-0.94),0.87(0.81-0.94),and 1.08(1.00-1.16)for alcohol abstinence,smoking cessation,and regular exercise,respectively.The adjusted HR(95%CI)for liver-related mortality was 0.92(0.80-1.06),0.81(0.72-0.91),and 1.15(1.04-1.27)for alcohol abstinence,smoking cessation,and regular exercise,respectively.CONCLUSION LSM lowered the risk of HCC and mortality in patients with CHB.Thus,active LSM,particularly alcohol abstinence and smoking cessation,should be encouraged in patients with CHB. | Yewan Park Danbee Kang Dong Hyun Sinn Hyunsoo Kim Yun Soo Hong Juhee Cho Geum-Youn Gwak | 2023 | World Journal of Gastroenterology2023，29，24： | 0 |
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