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| 1 | Epidemiology of gastroesophageal reflux disease:A general population-based study in Xi'an of Northwest China显示文摘AIM: Gastroesophageal reflux disease (GERD) is a common disorder in the Western population, but detailed population-based data in China are limited. The aim of this study was to understand the epidemiology of symptomatic gastroesophageal reflux (SGER) in adults of Xi'an, a northwestern city of China, and to explore the potential risk factors of GERD. METHODS: Symptoms suggestive of GERD, functional dyspepsia (FD), irritable bowel syndrome (IBS), upper respiratory diseases and some potential risk factors were investigated in a face-to-face manner in a region-stratified random samples of 2 789 residents aged 18-70 years in Xi'an by using a standardized questionnaire. METHODS: With a response rate of 91.8%, the prevalence of SGER was 16.98% (95% CI, 14.2-18.92) in Xi'an adults, and no gender-related difference was observed (P<0.05). SGER was more common among subjects aged 30-70 years than in those aged 18-29 years (P<0.01). The prevalence of SGER in rural, urban and suburban subjects was 21.07%, 17.44% and 12.12%, respectively, and there was a significant difference between rural, urban and suburban regions (P<0.05). Compared with subjects without SGER, the prevalence of symptoms suggestive of FD and IBS, pneumonia, asthma, bronchitis, laryngitis, pharyngitis, chronic cough, wheeze, globus sensation, oral ulcer and snore was significantly increased in subjects with SGER (P<0.01). Heavy smoking (OR=5.76; CI, 3.70-6.67), heavy alcohol use (OR=2.85; CI, 1.67-4.49), peplJc ulcer (OR=5.76; CI, 3.99-8.32), cerebral palsy (OR=3.97; CI, 1.97-8.00), abdominal operation (OR=2.69; CI, 1.75-4.13), obesity(OR=2.16; CI, 1.47-3.16), excessive food intake (OR= 1.43;CI, 1.17-1.15), sweet food (OR=1.23; CI, 0.89-1.54), and consumption of coffee (OR= 1.23; CI, 0.17-2.00) were independently associated with SGER. The episodes of GERD were commonly precipitated by dietary factors (66.05%), followed by body posture (26.54%), ill temper (23.72%), fatigue (22.32%) and stress (10.93%). CONCLUSION: GERD is common in Xi'an's adult population with a mild or moderate degree. The etiology and pathogenesis of GERD are probably associated with FD, IBS, and some respiratory, laryngopharyngeal and odontostological diseases or symptoms. Some lifestyles, diseases and dietary factors are the risk factors of GERD. | Jin-HaiWang Jin-YanLuo LeiDong JunGong MingTong | 2004 | World Journal of Gastroenterology2004，10，11： | 48 |
| 2 | Relationship of gastric Helicobacter pylori infection to Barrett's esophagus and gastro-esophageal reflux disease in Chinese显示文摘AIM:To evaluate the relationship of Helicobacter pylori infection to reflux esophagitis (RE), Barrett's esophagus (BE)and gastric intestinal metaplasia (IM).METHODS:RE,BE and gastric IM were determined by upper endoscopy. Patients were divided into 2 groups; those with squamocolumnar junction (SCJ) beyond gastroesophageal junction (GEJ)≥3cm (group A), and those with SCJ beyond GE.1 <3cm (group B). Biopsy specimens were obtainedend escopically from just below the SCJ, gastric antrum along the greater and lesser curvature. Pathological changes and Hpylorr infection were determined by HE staining, Alcian blue staining and Giemsa staining.RESULTS:The prevalence of Hpyloriinfection was 46.93%.There was no difference in the prevalence between males and females.The prevalence of Hpyloriinfection decreased stepwise significantly from RE grade I to Ⅲ.There was no difference in the prevalence between the two groups, and between long-segment and short-segment BE. In distal stomach, prevalence of Hpyloriinfection was significantly higher in patients with IM than those without IM.CONCLUSION: There is a protective role of Hpyloriinfectuion to GERD. There may be no relationship between Hpylori infection of stomach and BE. Hpyloriinfection is associated with the development of IN in the distal stomach. | JunZhang Xiao-LiChen Kang-MinWang Xiao-DanGuo Ai-LiZuo JunGong | 2004 | World Journal of Gastroenterology2004，10，5： | 12 |
| 3 | Effects of estradiol on liver estrogen receptor-α and its mRNA expression in hepatic fibrosis in rats显示文摘AIM:Estradiol treatment regulates estrogen receptor (ER) level in normal rat liver.However,little information is available concerning the role of estrogen in regulating liver ER in hepatic fibrosis in rats.The present study was conducted to determine whether estradiol treatment in CCl4-induced liver fibrosis of female and ovariectomized rats altered liver ERα and its mRNA expression,and to investigate the possible mechanisms.METHODS:Seventy female rats were divided into seven groups with ten rats in each. The ovariectomy groups were initiated with ovariectomies and the sham operation groups were initiated with just sham operations.The CCl4 toxic fibrosis groups received 400mL/L CCI4 subcutaneously at a dose of 2 mL/kg twice weekly.Estrogen groups were treated subcutaneously with estradiol 1mg/kg, the normal control group and an ovariectomy group received injection of peanut oil vehicle twice weekly.At the end of 8 weeks,all the rats were killed to detect their serum and hepatic indicators,their hepatic collagen content, and liver ER and ER mRNA expression.RESULTS: Estradiol treatment in both ovariectomy and sham ovariectomy groups reduced liver levels of ALT (from 658±220nkat/L to 311±146nkat/L and 540±252nkat/L to 314±163nkat/L,P<0.05) and AST (from 697±240nkat/L to 321±121nkat/L and 631±268nkat/L to 302±153nkat/L,P<0.05),increased serum nitric oxide (NO) level (from 53.7±17.1μmol/L to 93.3±4.2μmol/L and 55.3±3.1μmol/Lto 87.5±23.6μmol/L, P<0.05) and hepatic nitric oxide synthase (NOS) activity (from 1.73±0.71KU/g to 2.49±1.20KU/g and 1.65±0.46KU/g to 2.68±1.17KU/g, P<0.05),diminished the accumulation of hepatic collagen,decreased centrolobular necrotic areas as well as the inflammatory reaction in rats subjected to CCl4. The positive signal of ER and ER mRNA distributed in parenchymal and non-parenchymal hepatic cells,especially near the hepatic centrolobular and periportal areas.Ovariectomy decreased ER level (from 10.2±3.2 to 4.3±1.3) and ER mRNA expression (from 12.8±2.1 to 10.9±1.3) significantly (P<0.05). Hepatic ER and ER mRNA concentrations were elevated after treatment with estradiol in both ovariectomy (15.8±2.4, 20.8±3.1) and sham ovariectomy(18.7±3.8, 23.1±3.7) fibrotic groups (P | Jun-WangXu JunGong Xin-MingChang Jin-YanLuo LeiDong AiJia Gui-PingXu | 2004 | World Journal of Gastroenterology2004，10，2： | 8 |
| 4 | Attribute-based supervised deep learning model for action recognition显示文摘 | Kai CHEN Guiguang DING Jungong HAN | 2017 | Frontiers of Computer Science2017，11，2： | 7 |
| 5 | Barrett's esophagus and its correlation with gastroesophageal reflux in Chinese显示文摘AIM- To study the prevalence of Barrett's esophagus in Chinese and its correlation with gastroesophageal reflux. METHODS: This study was carded out in a large prospective series of 391 patients who had undergone upper endoscopy. The patients were divided into 3 groups according to the position of squamocolumnar junction (SC3). Reflux esophagitis (RE) and its degree were recorded. Intestinal metaplasia (IM) in biopsy specimen was typed according to histochemistry and HE and alcian blue (pH2.5) staining separately. Results correlating with clinical, endoscopic, and pathological data were analysed. RESULTS: The prevalence of IM endoscopically appearing Long-segment Barrett's Esophagus (LSBE) was 26.53%, Short-segment Barrett's Esophagus (SSBE) was 33.85% and gastroesophageal junction (GEJ) was 34.00%. IM increased with age of above 40 years old and no difference was found between male and female. Twelve were diagnosed as dysplasia (7 low -grade, 5 high-grade), 16 were diagnosed as cardiac adenocarcinoma and 1 as esophageal adenocarcinoma. The more far away the SCJ moved upward above GEJ, the higher the prevalence and the more severe the RE were. CONCLUSION: There was no difference of the prevalence of IM in different places of SCJ, and IM increased with age of above 40 years old. It is important to pay attention to dysplasia in the distal esophagus and gastro-esophageal junction, and adenocarcinoma is more common in cardia than in esophagus. BE is a consequence of gastroesophageal reflux disease. | JunZhang Xiao-LiChen Kang-MinWang Xiao-DanGuo Ai-LiZuo JunGong | 2004 | World Journal of Gastroenterology2004，10，7： | 7 |
| 6 | Preliminary analysis of distribution and variation of perennialmonthly mean water masses in the Bohai Sea,the Huanghai Sea and the East China Sea显示文摘On the basis of perennial monthly mean temperature and salinity data, the classification of monthly water masses at the surface and the bottom in the Bohai Sea, the Huanghai Sea and the East China Sea, has been made by using the method of fuzzy cluster from the modified characteristic of water masses in the shallow water area. In this paper, the basic features, growth and decline patterns of water masses in relation to fishing grounds in the whole shelves of the Bohai Sea, the Huanghai Sea and the East China Sea are discussed with emphasis. | Liu Shuxun, Shen Xinqiang, Wang Youqin and Han Shixin 1. East China Sea Fisheries Research Institute, No. 300, Jungong Road, Shanghai 200090, China | 1992 | Acta Oceanologica Sinica1992，11，4： | 6 |
| 7 | Gene expression profiling in Barrett's esophagus and cardia intestinal metaplasia: A comparative analysis using cDNA microarray显示文摘AIM: To study the difference of gene expression profile changes in Barrett's esophagus (BE) and cardia intestinal metaplasia (CIM) and to screen the novel genes in the early stage by cDNA microarray.METHODS: cDNA retrotranscribed from an equal amount of mRNA from BE and CIM epithelial tissues was labeled with Cy3 and Cy5 fluorescence as probes. The mixed probe was hybridized with three pieces of BiostarH-40 s double dot human whole gene chip. The chips were scanned with a ScanArray 4000. The acquired images were analyzed using GenePix Pro 3.0 software.RESULTS: A total of 141 genes were screened out that exhibited different expression in all three chips. There were 74 upregulated and 67 downregulated genes in gene expression profiles of BE which were two times of that in CIM.CONCLUSION: There is a difference in gene expression level between BE and CIM epithelia. These 141 genes probably relate to the occurrence and development of BE and the progression to adenocarcinoma. | YingChang JunGong BinLiu JunZhang FeiDai | 2004 | World Journal of Gastroenterology2004，10，21： | 4 |
| 8 | Relationship between deep-sea fish distributions and oceanic conditions of the East China Sea显示文摘Relationshipbetweendeep-seafishdistributionsandoceanicconditionsoftheEastChinaSea￥ShenJin'ao(ReceivedNovember17,1993;accepted... | Shen Jin’ao ( Department of Fishery Engineering, Shanghai Fisheries University, 334 Jungong Road, Shanghai 200090, China) | 1994 | Acta Oceanologica Sinica1994，13，4： | 3 |
| 9 | A Novel Method for Measuring the Coarse Water Droplets in Wet Steam Flow in Steam Turbines显示文摘Some optical probes based on light extinction have been developed to measure wetness dominated with fine droplets in steam turbine. However, coarse water droplets (hereafter referred to as CWD) that are the main cause of erosion of blade and of wetness loss of steam turbine can’t be detected by the extinction probes because of its large size. In this paper, a new method - the light fluctuation method is presented that is capable of measuring the she of CWD. A new probe based on this method was developed for measuring the she of CWD as well as its velocity and concentration. | Xiaoshu Cai Lin Wang Yongzhi Pan Xin Ouyan Jianqi Shen Faculty of Power Engineering, University of Shanghai for Science & Technology (USST), 516 Jungong Road, Shanghai 200093, China E-mail: caixs@public.sta.net.cn | 2001 | Journal of Thermal Science2001，10，2： | 2 |
| 10 | Composite score of reflux symptoms in diagnosis of gastroesophageal reflux disease显示文摘AIM: To evaluate the significance of the composite score of reflux symptoms in the diagnosis of gastroesophageal reflux disease (GERD), and to determine the relationship of the composite score with reflux esophagitis (RE) and pathological gastroesophageal reflux (PGER). METHODS: Upper digestive endoscopy and/or 24-h esophageal pH monitoring were performed in 244 subjects. Of these, 54 were consecutive patients attending our clinic with symptoms suggestive of GERD, and 190 were randomly selected from 2532 respondents who participated in our previous general population-based study on GERD. A standardized questionnaire was used to classify both the frequency and severity of typical symptoms of GERD (heartburn, acid and food regurgitation) using a 4-score scale, and the composite score of main reflux symptoms (score index: SI, range from 0 to 18) were calculated for every subject. RE was diagnosed according to the Savary-Miller criteria. Subjects with abnormal pH-metry (DeMeester score more than 14.7) were considered to have PGER. GERD patients were defined as the subjects with RE and/or PGER. RESULTS: The sensitivity of SI in the diagnosis of GERD was inversely associated with SI, but the specificity tended to increase with increased SI. With the cut-off of 8, the SI achieved the highest accuracy of 70.0%, with a sensitivity of 78.6% and a specificity of 69.2% in diagnosing GERD, followed by the cut-off of 3, which had an accuracy of 62.1%, a sensitivity of 96.4% and a specificity of 34.6%. The prevalence of RE, PGER and GERD was strongly associated with increased SI (P<0.01), but there was no significant association between the severity of RE and SI (P>0.05). Among patients with RE, 69.2% had PGER, and 30.8% were confirmed to have negative findings of pH monitoring. Among patients with PGER, 52.9% were identified to have RE and 47.1% had negative endscopic findings in esophagus. CONCLUSION: According to the composite score of main reflux symptoms, the diagnosis of GERD can be made without further tests in most cases. However, 24-h esophageal pH monitoring and upper digestive endoscopy are still indicated in patients with mild and atypical symptoms. | Jin-HaiWang Jin-YanLuo LeiDong JunGong Ai-LiZuo | 2004 | World Journal of Gastroenterology2004，10，22： | 2 |
| 11 | Gene expression in Barrett's esophagus and reflux esophagitis induced by gastroduodenoesophageal reflux in rats显示文摘AIM: To investigate the difference of gene expression profiles between Barrett's esophagus and reflux esophagitis induced by gastroduodenoesophageal reflux in rats.METHODS: Eight-week-old Sprague-Dawley rats were treated esophagoduodenostomy to produce gastroduodenoesophageal reflux, and another group received sham operation as control. Esophageal epithelial tissues were dissected and frozen in liquid nitrogen immediately for pathology 40 wk after surgery. The expression profiles of 4 096 genes in reflux esophagitis and Barrett's esophagus tissues were compared with normal esophageal epithelium by cDNA microarray.RESULTS: Four hundred and forty-eight genes in Barrett'sesophagus were more than three times different from those in normal esophageal epithelium, including 312 up regulated and 136 down-regulated genes. Two hundred and thirty-twogenes in RE were more than three times different from those in normal esophageal epithelium, 90up-regulated and 142 down-regulated genes. Compared to reflux esophagitis, there were 214 up-regulated and 142 down-regulated genes in Barrett's esophagus. CONCLUSION: Esophageal epithelium exposed excessively to harmful ingredients of duodenal and gastric reflux can develop esophagitis and Barrett's esophagus gradually.The gene expression level is different between reflux esophagitis and Barrett's esophagus and the differentially expressed genes might be related to the occurrence and development of Barrett's esophagus and the promotion or progression in adenocarcinoma. | PengCheng JunGong TaoWang ChenJie GuiShengLiu RuZhang | 2005 | World Journal of Gastroenterology2005，11，21： | 1 |
| 12 | Visible and infrared image registration in man-made environ ments employing hybrid visual features显示文摘 | HAN Jungong PAUWELS E J De ZEEU P | 2013 | Pattern Recognition Letters2013，34，1： | 1 |
| 13 | Intelligent trainee behavior assessment system for medical training emplo- ying video analysis显示文摘 | Jungong H Peter HN Merien A | 2012 | Part Recog Lett2012，，33： | 1 |
| 14 | Enhanced computer vision with Microsoft kinect sensor:a review显示文摘 | Han Jungong Shao Ling Xu Dong | 2013 | IEEE Transactions Cybern2013，43，5： | 1 |
| 15 | Visible anti infrared image registration in man-made environments em- ploying hybrid visual features显示文摘 | Han Jungong Pauwels Eric J de Zeeuw Paul | 2013 | Pattern recognition let- ters2013，34，1： | 1 |
| 16 | Densely nested top-down flows for salient object detection显示文摘With the goal of identifying pixel-wise salient object regions from each input image,salient object detection(SOD)has been receiving great attention in recent years.One kind of mainstream SOD method is formed by a bottom-up feature encoding procedure and a top-down information decoding procedure.While numerous approaches have explored the bottom-up feature extraction for this task,the design of top-down flows remains under-studied.To this end,this paper revisits the role of top-down modeling in salient object detection and designs a novel densely nested top-down flows(DNTDF)-based framework.In every stage of DNTDF,features from higher levels are read in via the progressive compression shortcut paths(PCSPs).The notable characteristics of our proposed method are as follows.(1)The propagation of high-level features which usually have relatively strong semantic information is enhanced in the decoding procedure.(2)With the help of PCSP,the gradient vanishing issues caused by non-linear operations in top-down information flows can be alleviated.(3)Thanks to the full exploration of high-level features,the decoding process of our method is relatively memory-efficient compared to those of existing methods.Integrating DNTDF with EfficientN et,we construct a highly light-weighted SOD model,with very low computational complexity.To demonstrate the effectiveness of the proposed model,comprehensive experiments are conducted on six widely-used benchmark datasets.The comparisons to the most state-of-the-art methods as well as the carefully-designed baseline models verify our insights on the top-down flow modeling for SOD. | Chaowei FANG Haibin TIAN Dingwen ZHANG Qiang ZHANG Jungong HAN Junwei HAN | 2022 | Science China(Information Sciences)2022，65，8： | 1 |
| 17 | Laminaria gametophyte clone culture and its application in sporeling cultivation显示文摘In China, the total annual production of cultured Laminaria japonica reached half million tons in dry weight there few years. The routine sporeling culture technique conducted in the greenhouse took at least three and half months. In such a case, sometimes the sporelings died within a few days due to destructive diseases. In Order to overcome the mentioned problems, a new sporeling culture technique, the clone technique, is developed. The method includes three stead: (1) Gametophyte clone culture. The spores and the gametophytes are cloned in flasks under favorable environments. (2) Sporeling cul ture. Male and female clones are crushed and spread onto a frame to allow the gametophytes to attach to the substrata. The frames are cultured in tanks, and the sporophytes reach 1 cm in length within one and a half months. (3) Outgrowing of the plant. The frames are put in the open sea when seawater temperature decreased to 20℃. After one month, the sporelings are large enough to be transplanted. It is concluded that the clone technique has the following advantages: (1)Large amount of clones can be produced in a short period of time. (2) Clone seeding method makes it free from the biological rhythm, one can seed the plant anytime all the year round. (3) It takes only one and a half months to complete the process of sporeling cultivation in the greenhouse. At present, this technique is used in the breeding of new strains of Laminaria. | Zhou Zhigang1 Li Dapeng2 Wu Chaoyuan2 Liu Haihang2 (1. Institute of Oceanology, Chinese Academy of Sciences, 7 Nanhai Road, Qingdao 266071, China. Prasent address: College of Fishery Science, Shanghai Fisheries University, 334 Jungong Road, Shangha 20 | 2000 | Acta Oceanologica Sinica2000，19，2： | 1 |
| 18 | Two Families of Liapunov Functions for Functional Differential Systems | Yi Zhang, Department of Computer Science and Engineering, University of Electronic Science and Technology of China, Chengdu 610054, P. R. ChinaMeijuan Wang, Department of Basic Studies, East China University of Technology, 516 Jungong Road Shanghai 200093, P. R. China | 1999 | Acta Mathematica Sinica,English Series1999，15，2： | 1 |
| 19 | Enhanced computer vision with microsoft kinect sensor: A review 显示文摘 | Han Jungong Shao Ling Xu Dong | 2013 | Cybernetics IEEE Transactions on2013，43，5： | 1 |
| 20 | Enhanced Computer Vision With Microsoft Kinect Sensor: A Re- view显示文摘 | Jungong Han Ling Shao Dong Xu | 2013 | IEEE Transactions on Cybernetics2013，43，5： | 1 |
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