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您的检索式：作者名="Junnan Tang"
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| 1 | An antioxidant system through conjugating superoxide dismutase onto metal-organic framework for cardiac repair显示文摘Acute myocardial infarction(AMI)remains a dominant origin of morbidity,mortality and disability worldwide.Increases in reactive oxygen species(ROS)are key contributor to excessive cardiac injury after AMI.Here we developed an immobilized enzyme with Superoxide Dismutase(SOD)activity cross-link with Zr-based metal-organic framework(ZrMOF)(SOD-ZrMOF)for mitigate ROS-caused injury.In vitro and in vivo evidence indicates that SOD-ZrMOF exhibits excellent biocompatibility.By efficiently scavenging ROS and suppressing oxidative stress,SOD-ZrMOF can protect the function of mitochondria,reduce cell death and alleviate inflammation.More excitingly,long-term study using an animal model of AMI demonstrated that SOD-ZrMOF can reduce the infarct area,protect cardiac function,promote angiogenesis and inhibit pathological myocardial remodeling.Therefore,SOD-ZrMOF holds great potential as an efficacious and safe nanomaterial treatment for AMI. | Jiacheng Guo Zhenzhen Yang Yongzheng Lu Chunyan Du Chang Cao Bo Wang Xiaoting Yue Zenglei Zhang Yanyan Xu Zhen Qin Tingting Huang Wei Wang Wei Jiang Jinying Zhang Junnan Tang | 2022 | Bioactive Materials2022，7，4： | 4 |
| 2 | Efficient photocatalytic hydrogen evolution coupled with benzaldehyde production over 0D Cd_(0.5)Zn_(0.5)S/2D Ti_(3)C2 Schottky heterojunction显示文摘Converting water into hydrogen fuel and oxidizing benzyl alcohol to benzaldehyde simultaneously under visible light illumination is of great significance,but the fast recombination of photogenerated carriers in photocatalysts seriously decreases the conversion efficiency.Herein,a novel dual-functional 0D Cd_(0.5)Zn_(0.5)S/2D Ti_(3)C2 hybrid was fabricated by a solvothermally in-situ generated assembling method.The Cd_(0.5)Zn_(0.5)S nano-spheres with a fluffy surface completely and uniformly covered the ultrathin Ti_(3)C2 nanosheets,leading to the increased Schottky barrier(SB)sites due to a large contact area,which could accelerate the electron–hole separation and improve the light utilization.The optimized Cd_(0.5)Zn_(0.5)S/Ti_(3)C2 hybrid simultaneously presents a hydrogen evolution rate of 5.3 mmol/(g·h)and a benzaldehyde production rate of 29.3 mmol/(g·h),which are~3.2 and 2 times higher than those of pristine Cd_(0.5)Zn_(0.5)S,respectively.Both the multiple experimental measurements and the density functional theory(DFT)calculations further demonstrate the tight connection between Cd_(0.5)Zn_(0.5)S and Ti_(3)C2,formation of Schottky junction,and efficient photogenerated electron–hole separation.This paper suggests a dual-functional composite catalyst for photocatalytic hydrogen evolution and benzaldehyde production,and provides a new strategy for preventing the photogenerated electrons and holes from recombining by constructing a 0D/2D heterojunction with increased SB sites. | Junnan TAO Mingyuan WANG Guiwu LIU Qinqin LIU Lei LU Neng WAN Hua TANG Guanjun QIAO | 2022 | Journal of Advanced Ceramics2022，11，7： | 1 |
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