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13篇 您的检索式:作者名="Junping Kou"
    题名 作者 年代 出处 被引量
1Social network search based on semantic analysis and learning显示文摘Feifei Kou Junping Du Yijiang He Lingfei Ye 2016CAAI Transactions on Intelligence Technology2016,1,4:11
2Danggui-shaoyao-san, a traditional Chinese medicine prescription, alleviates the orthodontic pain and inhibits neuronal and microglia activation显示文摘Li Hongshi Gu Zexu Wu Li'an Xia Liang Zhou Kecheng E Lingling Wang Dongsheng Kou Junping Liu Hongchen 2014Chinese Medical Journal2014,,20:4
3Author correction to'Ruscogenin alleviates LPS-triggered pulmonary endothelial barrier dysfunction through targeting NMMHC IIA to modulate TL R4 signaling’[Acta Pharmaceutica Sinica B 12(2022)1198-1212]显示文摘The authors regret that there were some errors or inexact de-scriptions in author afiliation,the section of materials and methods,and the figure caption of Fig.2A owing to the negligence of authors when writing the manuscript,and there was a picture error in Fig.10 and graphical abstract figure owing to the inappropriate selection for the picture of Radix Ophiopogon japonicus.In author afiliation,'Department of Pharmacology of Chinese Material Medica'should be corrected to'Department of Pharmacology of Chinese Materia Medica'.In 2.4.Yunhao Wu Xiu Yu Yuwei Wang Yalin Huang Jiahui Tang Shuaishuai Gong Siyu Jiang Yuanli Xia Fang Li Boyang Yu Yuanyuan Zhang Junping Kou 2022Acta Pharmaceutica Sinica B2022,12,7:3
4Anti-inflammatory activities of aqueous extract from Radix Ophiopogon japonicus and its two constituents 显示文摘Kou Junping Sun Yang Lin Yuwen 2005Biol Pharm Bull2005,28,7:1
5Antithrombotic activities of aqueous extract from radix Ophiopogon japonicus and its two constituents 显示文摘Junping Kou Youqing Tian Yunkit Tang 2006Biol Pharm Bull2006,29,6:1
6Antinociceptive and anti-inflammatory activities of Aquilaria sinensis (Lour.) Gilg. Leaves extract显示文摘Minhua Zhou Honggang Wang Suolangjiba Junping Kou Boyang Yu 2008Journal of Ethnopharmacology2008,,2:1
7Inhibitory effects of ethanol extract from Radix Ophiopogon japonicus on venous thrombosis linked with its endothelium-protective and anti-adhesive activities显示文摘KOU Junping YU Boyang XU Qiang 0,,03:1
8Antiinflammatory activity of Polygala japonica extract 显示文摘Junping Kou Minda Si Guofei Dai 2006Fitoterapia2006,77,:1
9Puerarin attenuates endothelial insulin resistance through inhibition of inflammatory response in an IKKβ/IRS-1-dependent manner显示文摘Fang Huang Kang Liu Hang Du Junping Kou Baolin Liu 2012Biochimie2012,,5:1
10Comparison of Neuroprotec- tive Effects of Flavonoids, Terpenoids and their Combinations from Ginkgo biloba on Ischemia- Reperfusion Injured Mice 显示文摘Mu Lingli Kou Junping Zhu Danni 2007Pharm Biol2007,45,9:1
11Inhibitory effects of ethanol extract from Radix Ophiopogon japonieus on venous thrombosis linked with its endothelium -protective and anti -adhesive activities 显示文摘Junping Kou Boyang Yu Qiang Xu 2005Vascular Pharmacology2005,43,3:1
12Few-shot node classification via local adaptive discriminant structure learning显示文摘Node classification has a wide range of application scenarios such as citation analysis and social network analysis.In many real-world attributed networks,a large portion of classes only contain limited labeled nodes.Most of the existing node classification methods cannot be used for few-shot node classification.To train the model effectively and improve the robustness and reliability of the model with scarce labeled samples,in this paper,we propose a local adaptive discriminant structure learning(LADSL)method for few-shot node classification.LADSL aims to properly represent the nodes in the attributed graphs and learn a metric space with a strong discriminating power by reducing the intra-class variations and enlargingginter-classdifferences.Extensiveexperiments conducted on various attributed networks datasets demonstrate that LADSL is superior to the other methods on few-shot node classification task.Zhe XUE Junping DU Xin XU Xiangbin LIU Junfu WANG Feifei KOU 2023Frontiers of Computer Science2023,17,2:0
13Ruscogenin alleviates LPS-triggered pulmonary endothelial barrier dysfunction through targeting NMMHC IIA to modulate TLR4signaling显示文摘Pulmonary endothelial barrier dysfunction is a hallmark of clinical pulmonary edema and contributes to the development of acute lung injury(ALI).Here we reported that ruscogenin(RUS),an effective steroidal sapogenin of Radix Ophiopogon japonicus,attenuated lipopolysaccharides(LPS)-induced pulmonary endothelial barrier disruption through mediating non-muscle myosin heavy chain IIA(NMMHC IIA)-Toll-like receptor 4(TLR4)interactions.By in vivo and in vitro experiments,we observed that RUS administration significantly ameliorated LPS-triggered pulmonary endothelial barrier dysfunction and ALI.Moreover,we identified that RUS directly targeted NMMHC IIA on its N-terminal and head domain by serial affinity chromatography,molecular docking,biolayer interferometry,and microscale thermophoresis analyses.Downregulation of endothelial NMMHC IIA expression in vivo and in vitro abolished the protective effect of RUS.It was also observed that NMMHC IIA was dissociated from TLR4 and then activating TLR4 downstream Src/vascular endothelial cadherin(VE-cadherin)signaling in pulmonary vascular endothelial cells after LPS treatment,which could be restored by RUS.Collectively,these findings provide pharmacological evidence showing that RUS attenuates LPS-induced pulmonary endothelial barrier dysfunction by inhibiting TLR4/Src/VE-cadherin pathway through targeting NMMHC IIA and mediating NMMHC IIA-TLR4 interactions.Yunhao Wu Xiu Yu Yuwei Wang Yalin Huang Jiahui Tang Shuaishuai Gong Siyu Jiang Yuanli Xia Fang Li Boyang Yu Yuanyuan Zhang Junping Kou 2022Acta Pharmaceutica Sinica B2022,12,3:0
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