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| 1 | Excellent Structure-Based Multifunction of Morpho Butterfly Wings: A Review显示文摘 | Shichao Niu Bo Li Zhengzhi Mu Meng Yang Junqiu Zhang Zhiwu Han Luquan Ren | 2015 | Journal of Bionic Engineering2015，12，2： | 19 |
| 2 | Erosion-Resistant Surfaces Inspired by Tamarisk显示文摘 | Zhiwu Han Wei Yin Junqiu Zhang Jialian Jiang Shichao Niu Luquan Ren | 2013 | Journal of Bionic Engineering2013，10，4： | 11 |
| 3 | Alginate oligosaccharide-induced intestinal morphology, barrier function and epithelium apoptosis modifications have beneficial effects on the growth performance of weaned pigs显示文摘Background: Alginate oligosaccharide(AOS), produced from alginate by alginate lyase-mediated depolymerisation, is a potential substitute for antibiotics and possesses growth-enhancing effects. Nevertheless, the mechanisms by which AOS regulates porcine growth remain to be elucidated. Therefore, we investigated the AOS-mediated changes in the growth performance of weaned pigs by determining the intestinal morphology, barrier function,as well as epithelium apoptosis.Methods: Twenty-four weaned pigs were distributed into two groups(n = 12) and received either a basal diet(control group) or the same diet supplemented with 100 mg/kg AOS. On d 15, D-xylose(0.1 g/kg body weight)was orally administrated to eight randomly selected pigs per treatment, and their serum and intestinal mucosa samples were collected 1 h later.Results: Our results showed that inclusion of AOS in the diet for 2 wk increased(P < 0.05) the average daily body weight gain in weaned pigs. Notably, AOS supplementation ameliorated the intestinal morphology and barrier function, as suggested by the enhanced(P < 0.05) intestinal villus height, secretory immunoglobulin A content and goblet cell counts. Compared to the control group, AOS ingestion both decreased(P < 0.05) the total apoptotic percentage and increased(P < 0.05) the proportion of S phase in the intestinal epithelial cells. Furthermore, AOS not only up-regulated(P < 0.05) the B-cell lymphoma-2(BCL2) transcriptional level but also down-regulated(P < 0.05) the B-cell lymphoma-2-associated X protein(BAX), cysteinyl aspartate-specific proteinase-3(caspase-3) and caspase-9 transcriptional levels in the small intestine.Conclusions: In summary, this study provides evidence that supplemental AOS beneficially affects the growth performance of weaned pigs, which may result from the improved intestinal morphology and barrier function,as well as the inhibited enterocyte death, through reducing apoptosis via mitochondria-dependent apoptosis. | Jin Wan Jiao Zhang Daiwen Chen Bing Yu Xiangbing Mao Ping Zheng Jie Yu Junqiu Luo Jun He | 2018 | Journal of Animal Science and Biotechnology2018，9，4： | 10 |
| 4 | Lentinan administration alleviates diarrhea of rotavirus-infected weaned pigs via regulating intestinal immunity显示文摘Background:Lentinan(LNT)may regulate many important physiological functions of human and animals.This study aimed to verify whether LNT administration could relieve diarrhea via improving gut immunity in rotavirus(RV)-challenged weaned pigs.Methods:Twenty-eight weaned pigs were randomly fed 2 diets containing 0 or 84 mg/kg LNT product for 19 d(n=14).RV infection was executed on d 15.After extracting polysaccharides from LNT product,its major monosaccharides were analyzed.Then,LNT polysaccharide was used to administrate RV-infected IPEC-J2 cells.Results:Dietary LNT supplementation supported normal function of piglets even when infected with RV,as reflected by reduced growth performance loss and diarrhea prevalence,and maintained gut immunity(P<0.05).The polysaccharide was isolated from LNT product,which molecular weight was 5303 Da,and major monosaccharides included glucose,arabinose and galactose.In RV-infected IPEC-J2 cells,this polysaccharide significantly increased cell viability(P<0.05),and significantly increased anti-virus immunity via regulating pattern recognition receptors and host defense peptides(P<0.05).Conclusion:Those results suggest that LNT administration increases the piglets’resistance to RV-induced stress,likely by supporting intestinal immunity. | Xiangqi Fan Haiyan Hu Daiwen Chen Bing Yu Jun He Jie Yu Junqiu Luo Erik Eckhardt Yuheng Luo Jianping Wang Hui Yan Xiangbing Mao | 2021 | Journal of Animal Science and Biotechnology2021，12，3： | 8 |
| 5 | Numerical Experiment of the Solid Particle Erosion of Bionic Configuration Blade of Centrifugal Fan显示文摘In this paper, a bionic method was presented to improve the erosion resistance of blade of the centrifugal fan. A numerical investigation of the solid particle erosion on the standard and bionic configuration blade of 4-72N10C centrifugal fan was presented. The numerical study employs computational fluid dynamics (CFD) software, based on a finite volume method, in which the discrete phase model was used to modele the solid particles flow, and the Eulerian conservation equation was adopt to simulate the continuous phase. Moreover, user-defined function was used to define wear equation. The various diameters of the particles were taken into account. The positions of collision of standard and bionic fan blades were discussed, and two kinds of centrifugal fan blade wear were compared. The results show that the particles from the incident source with different positions have different processes of turning and movement when enter into the impeller. The trajectories of flow in the fan channel are significantly different for the particles with different diameters. Bionic fan blade have lower erosion rate than the standard fan blade when the particle size is 20 μm. The anti-erosion mechanism of the bionic fan blade was discussed. | Junqiu ZHANG Zhiwu HAN Wei YIN Huiyuan WANG Chao GE Jialian JIANG | 2013 | Acta Metallurgica Sinica(English Letters)2013，26，1： | 8 |
| 6 | Arabidopsis VQ10 interacts with WRKY8 to modulate basal defense against Botrytis cinerea显示文摘Recent studies in Arabidopsis have revealed that some VQ motif-containing proteins physically interact with WRKY transcription factors;however,their specific biological functions are still poorly understood.In this study,we confirmed the interaction between VQ10and WRKY8,and show that VQ10 and WRKY8 formed a complex in the plant cell nucleus.Yeast two-hybrid analysis showed that the middle region of WRKY8 and the VQ motif of VQ10 are critical for their interaction,and that this interaction promotes the DNA-binding activity of WRKY8.Further investigation revealed that the VQ10protein was exclusively localized in the nucleus,and VQ10was predominantly expressed in siliques.VQ10 expression was strongly responsive to the necrotrophic fungal pathogen,Botrytis cinerea and defense-related hormones.Phenotypic analysis showed that disruption of VQ10 increased mutant plants susceptibility to the fungal pathogen B.cinerea,whereas constitutive-expression of VQ10 enhanced resistance to B.cinerea.Consistent with these findings,expression of the defenserelated PLANT DEFENSIN1.2(PDF1.2)gene was decreased in vq10 mutant plants,after B.cinerea infection,but increased in VQ10-overexpressing transgenic plants.Taken together,our findings provide evidence that VQ10 physically interacts with WRKY8 and positively regulates plant basal resistance against the necrotrophic fungal pathogen B.cinerea. | Junqiu Chen Houping Wang Yang Li Jinjing Pan Yanru Hu Diqiu Yu | 2018 | Journal of Integrative Plant Biology2018，60，10： | 8 |
| 7 | Artificial Hair-Like Sensors Inspired from Nature: A Review显示文摘 | Zhiwu Han Linpeng Liu Kejun Wang Honglie Song Daobing Chen Ze Wang Shichao Niu Junqiu Zhang Luquan Ren | 2018 | Journal of Bionic Engineering2018，15，3： | 6 |
| 8 | Anti-adhesive Property of Maize Leaf Surface Related with Temperature and Humidity显示文摘 | Zhiwu Han Jia Fu Yuqiang Fang Junqiu Zhang Shichao Niu Luquan Ren | 2017 | Journal of Bionic Engineering2017，14，3： | 5 |
| 9 | Tannic acid extracted from gallnut prevents post-weaning diarrhea and improves intestinal health of weaned piglets显示文摘This experiment was conducted to evaluate the effects of different levels of tannic acid(TA)on growth performance,diarrhea rate,nutrient digestibility and intestinal health in weaned piglets.A total of 180 weaned piglets(Duroc×Landrace×Yorkshire,24 d of age,initial average BW=7.77±0.17 kg)were allotted to 5 groups(6 pigs/pen and 6 replicates/group)in a randomized complete block design according to their gender and body weight.Piglets were fed a basal diet,or the basal diet supplemented with 0.05%,0.1%,0.2%or 0.4%TA for 28 d.The supplementary levels of TA in the diets were obtained by adding tannalbin containing 51%TA and 40.17%protein.The results showed that,compared with the CON group,dietary TA did not affect ADFI,ADG or F:G,and linearly reduced(P<0.01)the diarrhea rate and diarrhea index of piglets.There were no significant effects on apparent total tract digestibility(ATTD)in the 0.05%,0.1%and 0.2%TA groups,while negative effects(P<0.05)on apparent digestibility of crude protein and gross energy were observed in the 0.4%TA group.In addition,the nutrient digestibility of dry matter,crude protein and gross energy linearly decreased(P<0.01)with the increase of TA dosage.Supplementation of TA increased(P<0.05)the villus height of the duodenum and jejunum,as well as increased(P<0.05)catalase(CAT)activity in serum.Dietary TA improved(P<0.05)the Bacillus counts in cecal digesta.Further,TA significantly improved(P<0.05)Bacillus counts and reduced(P<0.05)the Escherichia coli counts in colonic digesta.The concentration of acetic acid,pro pionic acid,butyric acid and isovaleric acid in cecal digesta were significantly increased(P<0.05).The mRNA expression level of zonula occludens-1(Z0-1),zonula occludens-2(ZI-2),and claudin-2(CLDN-2)in the jejunum were greater(P<0.05)in TA supplemented groups.The study showed that,compared to the control,TA prevented post-weaning diarrhea and improved intestinal health of weaned piglets,and the appropriate level of TA supplementation would be from 0.1%to 0.2%. | Yanyan Song Yong Luo Bing Yu Jun He Ping Zheng Xiangbing Mao Zhiqing Huang Junqiu Luo Yuheng Luo Hui Yan Quyuan Wang Huifen Wang Daiwen Chen Jie Yu | 2021 | Animal Nutrition2021，，4： | 5 |
| 10 | Differential expression, molecular cloning,and characterization of porcine beta defensin 114显示文摘Background:β-defensins have attracted considerable research interest because of their roles in protecting hosts from various pathogens.This study was conducted to investigate the expression profiles of the porcineβ-defensin114(PBD114)in different breeds and in response to infections.Moreover,the function of PBD114 protein was partially investigated.Methods:Six Tibetan pigs(TP)and six DLY(Duroc×Landrace×Yorkshire)pigs were slaughtered to explore the expression profiles of PBD114 in different breeds and tissues.For infection models,sixteen DLY pigs were divided into two groups and challenged either with sterile saline or E.coli K88.The recombinant protein PBD114(r PBD114)was obtained by using a heterologous expression system in E.coli.Results:PBD114 gene was highly expressed in tissues such as the intestine,liver,spleen,and thymus.Interestingly,the expression level of PBD114 gene was higher in the TP pigs than in the DLY pigs(P<0.05),and was significantly elevated upon E.coli K88 challenge(P<0.05).The nucleotide sequences of PBD114 from Tibetan and DLY pigs was identical,and both showed a 210-bp open reading frame encoding a 69-amino acid mature peptide.To explaore the function of PBD114 protein,PBD114 gene was successfully expressed in E.coli Origami B(DE3)and the molecular weight of the r PBD114 was estimated by SDS-PAGE to be 25 k Da.The r PBD114 was purified and mass spectrometry verified the protein as PBD114.Importantly,r PBD114 showed antimicrobial activities against E.coli DH5αand E.coli K88,and the minimal inhibitory concentrations(MICs)were 64 and 128μg/m L,respectively.Hemolytic and cytotoxicity assays showed that r PBD114 did not affect cell viability under physiological concentrations.Conclusions:PBD114 is an infection response gene that is differentially-expressed between different porcine breeds and tissues.The antimicrobial activity of PBD114 protein,against pathogens such as the E.coli K88,suggested that it may serve as a candidate for the substitution of conventionally used antibiotics. | Guoqi Su Kunhong Xie Daiwen Chen Bing Yu Zhiqing Huang Yuheng Luo Xiangbing Mao Ping Zheng Jie Yu Junqiu Luo Jun He | 2019 | Journal of Animal Science and Biotechnology2019，10，4： | 4 |
| 11 | Angle-dependent discoloration structures in wing scales of Morpho menelaus butterfly显示文摘The Morpho butterfly is famous for its typical structural color and has increasingly attracted the interest of scholars in a wide variety of research fields. Herein, it was found that the color of Morpho menelaus butterfly wings is not only structure-based but also viewing-angle-dependent. Firstly, the discoloration effect of this typical butterfly was confirmed by a series of experiments. Then, the general form, arrangements, and geometrical dimensions of the scales were observed using a stereomicroscope. Scanning electron microscopy was also used to examine the two-dimensional morphologies and structures of a single scale. Afterwards, one model with the optimized three-dimensional profile of the structure was described using Pro-engineer software. The associate model was then analyzed to reconstruct the process between the incident light and the model surface. Finally, the mechanism of the angle-dependent discoloration effect was analyzed by theoretical calculation and optical simulation. Different light propagation paths and the length of the incident light at different angles caused destructive or constructive interference between the light reflected from the different layers. The different spectra of the reflected light make the wings appear with different structural colors, thereby endowing the angle-dependent discoloration effect. The consistency of the calculation and simulation results confirms that these structures possess an excellent angle-dependent discoloration effect. This functional 'biomimetic structure' would not only be of great scientific interest but could also have a great impact in a wide range of applications such as reflective displays, credit card security, and military stealth technology. | NIU ShiChao LI Bo YE JunFeng MU ZhengZhi ZHANG JunQiu LIU Yan HAN ZhiWu | 2016 | Science China(Technological Sciences)2016，59，5： | 4 |
| 12 | Supplementing daidzein in diets improves the reproductive performance, endocrine hormones and antioxidant capacity of multiparous sows显示文摘Certain hormones play important roles in modulating mammalian reproductive behaviour.Daidzein is a well-known isoflavonic phytoestrogen that possesses oestrogenic activity.This study was conducted to probe the effects of daidzein supplementation in gestation diets on the reproductive performance in sows.A total of 120 multiparous sows(Landrace x Yorkshire)were randomly assigned to 2 groups(n=60)and fed either a base diet(control)or one containing 200 mg/kg daidzein during gestation.We discovered that daidzein supplementation significantly increased the total number of piglets born per litter and number of piglets born alive per litter(P<0.05),decreased the farrowing time(P<0.05)and increased the serum oestrogen and progesterone concentrations(P<0.05)at 35 d of gestation.Moreover,serum immunoglobulin G(IgG)concentration and superoxide dismutase(SOD)and glutathione peroxidase(GSH-Px)activities were higher in the daidzein-treated group than in the control group at35 d of gestation(P<0.05).Daidzein increased the serum SOD activity and total anti-oxidative capacity(T-AOC)at 85 d of gestation(P<0.05).Interestingly,daidzein elevated the expression levels of the sodium-coupled neutral amino acid transporter 1(SLC38 A1)and insulin-like growth factor 1(IGF-1)genes in the placenta(P<0.05).These results suggest that daidzein ingestion could improve sow reproductive performance by changing serum hormones,elevating anti-oxidative capacity and upregulating critical functional genes in the placenta. | Yan Li Guoru He Daiwen Chen Bing Yu Jie Yu Ping Zheng Zhiqing Huang Yuheng Luo Junqiu Luo Xiangbing Mao Hui Yan Jun He | 2021 | Animal Nutrition2021，，4： | 4 |
| 13 | Biosynthesis of selenosubtilisin: A novel way to target selenium into the active site of subtilisin显示文摘Glutathione peroxidase (GPx, EC1.11.1.9), an important anti-oxidative selenoenzyme, can catalyze the reduction of harmful hydroperoxides with concomitant glutathione, thereby protecting cells and other biological issues against oxidative damage. It captures considerable interest in redesign of its function for either the mechanism study or the pharmacological development as an antioxidant. In order to de- velop a general strategy for specifically targeting and operating selenium in active sites of enzymes, the catalytically essential residue selenocysteine (Sec) was first successfully bioincorporated into the catalytic center of subtilisin by using an auxotrophic expression system. The studies of the catalytic activity and the steady-state kinetics demonstrated that selenosubtilisin is an excellent GPx-like bio- catalyst. In comparison with the chemically modified method, biosynthesis exhibits obvious advan- tages: Sec could be site-directly incorporated into active sites of enzymes to overcome the non-speci- ficity generated by chemical modification. This study provides an important strategy for specifically targeting and operating selenium in the active site of an enzyme. | LI Jing LIU XiaoMan JI YueTong QI ZhenHui GE Yan XU JiaYun LIU JunQiu LUO GuiMin SHEN JiaCong | 2008 | Chinese Science Bulletin2008，53，16： | 3 |
| 14 | Tannic acid prevents post-weaning diarrhea by improving intestinal barrier integrity and function in weaned piglets显示文摘Background:Tannic acid(TA)is potential to reduce diarrhea in weaning pigs,but knowledge about the influence of TA on intestinal barrier integrity and function is still scarce.This experiment was conducted to investigate the effects of dietary TA supplementation on growth performance,diarrhea rate,intestinal barrier integrity and function of weaned pigs.Methods:A total of 108 crossbred(Duroc×Landrace×Yorkshire)piglets,with an initial average body weight of 6.60±0.27 kg,were allotted to 3 groups(6 pigs/pen and 6 replicates/group)in a randomized complete block design according to their gender and body weight.Piglets were fed the basal diet with 0(control,CON),0.2%and 1.0%TA,respectively.The trial lasted for 28 d.Results:Compared with the CON group,dietary 0.2%and 1.0%TA supplementation didn’t affect ADFI,ADG and F:G(P>0.05),but reduced diarrhea rate,diarrhea index and diarrhea score of piglets(P<0.05),reduced diamine oxidase(DAO)activity and D-lactic acid concentration in serum(P<0.01).The higher occludin expression and localization were observed in the duodenum,jejunum and ileum after supplementation with 0.2%or 1.0%TA(P<0.05).Adding 0.2%TA to diet significantly decreased crypt depth,increased villus height/crypt depth ratio in the duodenum(P<0.05),and dietary 1.0%TA tended to decrease crypt depth(P<0.10)and significantly decreased villus height(P<0.05)of the ileum.Moreover,lower malondialdehyde content in the ileum was detected in the pigs fed 1.0%TA(P<0.05).In the duodenum,both 0.2%and 1.0%TA groups had higher occludin(OCLN)mRNA and 0.2%TA group had higher zonula occludens-2(ZO-2)level(P<0.05).Meanwhile,dietary 1.0%TA supplementation tended to up-regulate OCLN mRNA levels in the jejunum(P<0.10)and 0.2%TA supplementation tended to up-regulate zonula occludens-1(ZO-1)mRNA levels in the ileum(P<0.10).Conclusion:In conclusion,dietary supplementation of 0.2%or 1.0%TA could effectively alleviate postweaning diarrhea without altering growth performance in weaned piglets,which might be achieved by improving intestinal barrier integrity and function. | Jie Yu Yanyan Song Bing Yu Jun He Ping Zheng Xiangbing Mao Zhiqing Huang Yuheng Luo Junqiu Luo Hui Yan Quyuan Wang Huifen Wang Daiwen Chen | 2021 | Journal of Animal Science and Biotechnology2021，12，2： | 3 |
| 15 | Ablation Performance of a Novel Super-hybrid Composite显示文摘A novel super-hybrid composite (NSHC) was boron-modified phenolic resin (BPR) with three-dimensional reticulated SiC ceramic (3DRC) and high silica fibers. Ablation performance of the NSHC was studied. The results show that the linear ablation rate of NSHC was lower than that of pure BPR and the high silica/BPR composite. Its linear ablation rate is 1/17 of the high silica/BPR. Mass ablation rate of the NSHC is very close to that of the pure BPR and the high silica/BPR composite. Scanning electron microscope (SEM) analysis indicates that 3DRC has scarcely changed its shape at the ablation temperature. Its special reticulated structure can restrict the materials deformation and prevent high velocity heat flow from eroding the surface of the materials largely and thus increase ablation resistance of the NSHC. | JunQIU XiaomingCAO ChongTIAN JinsongZHANG | 2005 | Journal of Materials Science & Technology2005，21，2： | 3 |
| 16 | Atmospheric pollution of agriculture-oriented cities in Northeast China: A case in Suihua显示文摘Agriculture-oriented cities in Northeastern China have experienced frequent atmospheric pollution events.Deeper understandings of the pollution characteristics,haze causes and effects of management on local air quality are crucial for conducting integrated management approaches for the sustainable development of agriculture-oriented cities.Taking a typical agriculture-dominant city(i.e.,Suihua)in Northeast China,we analyzed in detail the characteristics and causes of atmospheric pollution and evaluated the straw-burning prohibition using multisource data.The results showed a clear temporal pattern of air quality index(AQI)on an annual scale(i.e.,2015-April 2019),with two typical pollution periods occurring in late autumn and early spring.The large areas of concentrated straw burning at local and regional scales accounted for the first period(i.e.,October and November),while dust emissions and farming disturbances comprised the second period.The interannual variation in pollution periods among these years was large,showing similar trends from 2015 to 2017 and the postponed late-autumn pollution period in 2018.Our evaluation has shown that the prohibition effect of straw burning significantly improved air quality in 2018,with a reduction of 59%±88%in the PM2.5 concentrations in October and November compared to 2015–2017.However,From October to April of the following year,the improvement effect was not significant due to postponement of straw burning to February or March.Our analysis also highlighted the roles of meteorological conditions,Therefore,combined with the promotion of straw utilization,scientifically prescribed burning considering the burning amount and location,meteorological conditions and regional transportation should be implemented. | Lili Li Kun Wang Weiwei Chen Qingliang Zhao Lijuan Liu Wei Liu Yang Liu Junqiu Jiang Jiumeng Liu Mengduo Zhang | 2020 | Journal of Environmental Sciences2020，32，11： | 3 |
| 17 | Leucine modulates the IPEC-J2 cell proteome associated with cell proliferation, metabolism and phagocytosis显示文摘Leucine can affect intestinal protein expressions, and improve mucosal immune function. However, little study has been conducted to determine the change of protein component by leucine treatment in intestine epithelial cells. The present study was to cover the key proteins and cell pathways that could be regulated by leucine treatment in porcine intestinal epithelial cell line(IPEC-J2) cells with the approach of proteome analysis. A total number of 3,211 proteins were identified in our approach by searching the database of Uniprot sus scrofa. Among identified proteins, there were 101 proteins expressed differently between control group and leucine group. Compared with the control group, there were 50 up-regulated proteins and 51 down-regulated proteins in leucine group. In these proteins, leucine treatment decreased the expression of some proteins including pyruvate kinase, glyceraldehyde-3-phosphate dehydrogenase,E3 ubiquitin ligase, cathepsin D, caspase 3 and caspase 6, and increased the levels of some proteins, such as some eukaryotic translation initiation factors, ubiquitin carboxyl-terminal hydrolase, DNA-related RNA polymerase II, urokinase plasminogen activator, cyclin-dependent kinase inhibitor 2 b, Mut L homolog 1,5-methylcytosine binding domain 4, polymerase d, a-tubulin, syntaxin 18, Ras homolog D, actin related protein 2/3 complex and cofilin. Via the analysis of Gene Ontology and pathways, these proteins in IPECJ2 cells were related with some physiological functions, such as protein metabolism, glycolysis, cell proliferation, apoptosis and phagocytosis. Thus, these results suggest that leucine affects gut barrier function possibly via regulating cell proliferation and apoptosis, metabolism and phagocytosis. | Xiangbing Mao Man Ren Daiwen Chen Bing Yu Lianqiang Che Jun He Junqiu Luo Yuheng Luo Jianping Wang Hui Sun | 2018 | Animal Nutrition2018，，3： | 2 |
| 18 | Preheating method of lithium-ion batteries in an electric vehicle显示文摘To improve the low-temperature charge-discharge performance of lithium-ion battery,low-temperature experiments of the charge-discharge characteristics of 35 Ah high-power lithium-ion batteries have been conducted,and the wide-line metal film method for heating batteries is presented.At-40℃,heating and charge-discharge experiments have been performed on the battery pack.The results indicate the charge-discharge performance is substantially worse in cold climates,and can be significantly improved by heating the battery pack with a wide-line metal film.Pulse charge-discharge experiments show that at-40℃ambient temperature,the heated battery pack can charge or discharge at high current and offer almost80%power. | Zhiguo LEI Chengning ZHANG Junqiu LI Guangchong FAN Zhewei LIN | 2015 | Journal of Modern Power Systems and Clean Energy2015，3，2： | 2 |
| 19 | Lower abundance of Bacteroides and metabolic dysfunction are highly associated with the post-weaning diarrhea in piglets显示文摘Growing evidences show a direct link between diarrhea and disorders of gut microbiota in pigs.However,whether there are microbial markers associated with post-weaning diarrhea remains unknown.In the current study,we compared the microbial community,functions and metabolites between healthy weaned piglets(group H,n=7)and piglets with post-weaning diarrhea(group D,n=7),in order to find out diarrhea associated microbial markers.Each of 7 fecal samples was collected from H and D piglets(weaned at 21 d and sampled at 26 d).The metagenomic and untargeted metabolomic analysis revealed that the microbial composition,function and metabolic profile in D pigs was considerably reshaped,including the reduced abundance and number of Bacteroides,which significantly correlated with the diarrhea status of host.The carbohydrate metabolism,biosynthesis and metabolism,lipid metabolism,amino acid metabolism,and the activity of glycan and carbohydrates digestion related enzymes showed extensively down-regulated in D pigs compared with H pigs.Diarrhea significantly changed the metabolic profiles of fecal microbiota,and most of the altered metabolites were negatively or positively correlated with the change in the abundance of Bacteroides.In conclusion,the lower abundance of Bacteroides and its associated metabolic dysfunction may be regarded as microbial markers of physiological post-weaning diarrhea in piglets. | Wen Ren Bing Yu Jie Yu Ping Zheng Zhiqing Huang Junqiu Luo Xiangbing Mao Jun He Hui Yan Jinlong Wu Daiwen Chen Yuheng Luo | 2022 | Science China(Life Sciences)2022，65，10： | 2 |
| 20 | The Late Triassic I-Type Granites from the Longmu Co-Shuanghu Suture Zone in the interior of Tibetan Plateau, China: Petrogenesis and Implication for Slab Break-Off显示文摘The Jiangaidarina granitic mass(JM) is an important part of the magmatic belt in Longmu CoShuanghu Suture Zone(LSSZ) in the central Tibetan Plateau. An integrated research involving wholerock geochemistry, zircon LA-ICP-MS U-Pb ages and Hf isotopic compositions was carried out to define the timing, genesis and tectonic setting of the JM. Zircon LA-ICP-MS U-Pb ages have been obtained ranging from 210 to 215 Ma, rather than the Early Jurassic as previously thought. Fifteen granite samples contain hornblendes and show a negative correlation between P_2 O_5 and SiO_2, indicating that the JM is an I-type granite. All the granites are enriched in LREE relative to HREE, with negative Eu anomalies(Eu/Eu*=0.56-0.81), and have similar trace elements patterns, with depletion of Ba, Nb, Sr and P. These suggest that the JM was fractionated, and this is also proved by the characteristic of negative correlations between oxide elements(TiO_2, MgO, FeOt, MnO, CaO) and SiO_2. Almost all ε_(Hf)(t) values of the granites are between-10.3 and-5.8, implying that the JM has a crustal source intimately related with the South Qiangtang Block(SQB), except for one(+10.2), showing a minor contribution from mantle source.Moreover, relatively low Na_2 O/K_2 O ratios(0.42-0.93) and high A/CNK values(0.91-1.50) reflect that the JM was predominately derived from the medium-high potassium basaltic crust, interacted with greywacke. Our new geochemical data and geochronological results imply that the Late Triassic magmas were generated in a post-collisional tectonic setting, probably caused by slab break-off of the Longmu Co-Shuanghu Tethyan Ocean(LSTO). This mechanism caused the asthenosphere upwelling, formed extension setting, offered an enormous amount of heat, and provided favorable conditions for emplacement of voluminous felsic magmas. Furthermore, the LSTO could be completely closed during the Middle Triassic, succeed by continental collision and later the slab broke off in the Late Triassic. | ZHAO Zhen WU Zhenhan LU Lu YU Junqiu WU Yanjun | 2018 | Acta Geologica Sinica(English Edition)2018，92，3： | 2 |
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