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| 1 | Development of an Arabic version of the National Eye Institute Visual Function Questionnaire as a tool to study eye diseases patients in Egypt显示文摘AIM:To develop and test an Arabic version of the National Eye Institute Visual Function Questionnaire-25(NEI-VFQ-25).METHODS:NEI-VFQ-25 was translated into Arabic according to WHO translation guidelines. We enrolled adult consenting patients with bilateral chronic eye diseases who presented to 14 hospitals across Egypt from October to December 2012, and documented their clinical findings. Psychometric properties were then tested using STATA.RESULTS:We recruited 379 patients, whose mean age was(54.5±15)y. Of 46.2% were males, 227 had cataract,31 had glaucoma, 23 had retinal detachment, 37 had diabetic retinopathy, and 61 had miscellaneous visual defects. Non-response rate and the floor and ceiling numbers of the Arabic version(ARB-VFQ-25) were calculated. Internal consistency was high in all subscales(except general health), with Cronbach-α ranging from0.702-0.911. Test-retest reliability was high(intraclass correlation coefficient 0.79).CONCLUSION:RB-VFQ-25 isareliableandvalidtool for assessing visual functions of Arabic speaking patients. However, some questions had high non-response rates and should be substituted by available alternatives. Our results support the importance of including self-reported visual functions as part of routine ophthalmologic examination. | Nizar Saleh Abdelfattah Mohamed Amgad Ahmed A Salama Marina E Israel Ghada A Elhawary Ahmed E Radwan Mohamed M Elgayar Tamer M EL Nakhal Islam T Elkhateb Heba A Hashem Doha K Embaby Amira A Elabd Reem K Elwy Magdi S Yacoub Hamdy Salem Mohamed Abdel-Baqy Ahmad Kassem | 2014 | International Journal of Ophthalmology(English edition)2014，7，5： | 8 |
| 2 | Tumor necrosis factor-α-G308A polymorphism is associated with liver pathological changes in hepatitis C virus patients显示文摘AIM To investigate the association of tumor necrosis factor alpha(TNFα)-G308 A polymorphism with different liver pathological changes in treatment-na?ve Egyptian patients infected with hepatitis C virus(HCV) genotype 4.METHODS This study included 180 subjects,composed of 120 treatment-na?ve chronic HCV patients with different fibrosis grades(F0-F4) and 60 healthy controls. The TNFα-G308 A region was amplified by PCR and the different genotypes were detected by restriction fragment length polymorphism analysis. The TNFα protein was detected by enzyme-linked immunosorbent assay. The influence of different TNFα-G308 A genotypes on TNFα expression and liver disease progression were statistically analyzed. The OR and 95%CI were calculated to assess the relative risk confidence.RESULTS Current data showed that the TNFα-G308 A SNP frequency was significantly different between controls and HCV infected patients(P = 0.001). Both the AA genotype and A allele were significantly higher in late fibrosis patients(F2-F4,n = 60) than in early fibrosis patients(F0-F1,n = 60)(P = 0.05,0.04 respectively). Moreover,the GA or AA genotypes increased the TNFα serum level greater than the GG genotype(P = 0.002). The results showed a clear association between severe liver pathological conditions(inflammation,steatosis and fibrosis) and(GA + AA) genotypes(P = 0.035,0.03,0.04 respectively). The stepwise logistic regression analysis showed that the TNFα genotypes(GA + AA) were significantly associated with liver inflammation(OR = 3.776,95%CI: 1.399-10.194,P = 0.009),severe steatosis(OR = 4.49,95%CI: 1.441-14.0,P = 0.010) and fibrosis progression(OR = 2.84,95%CI: 1.080-7.472,P = 0.034). Also,the A allele was an independent risk factor for liver inflammation(P = 0.003),steatosis(P = 0.003) and fibrosis(P = 0.014). CONCLUSION TNFα SNP at nucleotide-308 represents an important genetic marker that can be used for the prognosis of different liver pathological changes in HCV infected | Noha G Bader El Din Sally Farouk Reem El-Shenawy Marwa K Ibrahim Reham M Dawood Mostafa M Elhady Ahmed M Salem Naglaa Zayed Ahmed Khairy Mostafa K El Awady | 2016 | World Journal of Gastroenterology2016，22，34： | 3 |
| 3 | Synthesis of unsaturated polyester resins based on rosin acrylic acid adduct for coating applications显示文摘 | Ayman M Atta Ashraf M Elsaeed Reem K Farag | 2007 | Reactive and Functional Polymers2007，67，： | 1 |
| 4 | Synthesis of unsaturated polyester resins based on rosin acrylic acid adduct for coating applications 显示文摘 | Ayman M Atta Ashraf M Elsaeed Reem K Farag | 2007 | Reactive & Functional Polymers2007，，67： | 1 |
| 5 | Crosslinked cinnamoyloxyethyl methacrylate and isooctyl acrylate copolymers as oil sorbers显示文摘 | Atta Ayman M El-Ghazawy Rasha A M Farag Reem K | | 0，，07： | 1 |
| 6 | Demulsifier systems applied to breakdown petroleum sludge 显示文摘 | Abdel-Azim A Abdel Azim Abdul-Raheim M Abdul-Raheim Reem K Kamel | 2011 | Journal of Petroleum Science and Engi- neering2011，78，： | 1 |
| 7 | 显示文摘 | Ayman M A Rasha A E G Reem K F | 2005 | Polym Int2005，54，： | 1 |
| 8 | 显示文摘 | Ayman M A Rasha A E G Reem K F | 2006 | React Funct Polym2006，66，： | 1 |
| 9 | New vinyl ester resins based on rosin for coating 显示文摘 | Ayman M A Shymaa M E Reem K F | 2006 | Applications Reactive & Functional Polymers2006，66，12： | 1 |
| 10 | Synthesis of unsaturated polyester resins based on rosin acrylic acid adduct for coating applications显示文摘 | Ayman M A Shymaa M E Reem K F | 2007 | Reactive and Functional Polymers2007，67，6： | 1 |
| 11 | Genetic association of apolipoprotein E polymorphisms with inflammatory bowel disease显示文摘AIM:To study the association of apolipoprotein E(APOE) polymorphisms with the susceptibility ofinflammatory bowel disease(IBD) in Saudi patients.METHODS:APOE genotyping was performed to evaluate the allele and genotype frequencies in 378 Saudi subjects including IBD patients with ulcerative colitis(n = 84) or Crohn's disease(n = 94) and matched controls(n = 200) using polymerase chain reaction and reverse-hybridization techniques.RESULTS:The frequencies of the APOE ε2 allele and ε2/ε3 and ε2/ε4 genotypes were significantly higher in IBD patients than in controls(P < 0.05),suggesting that the ε2 allele and its heterozygous genotypes may increase the susceptibility to IBD.On the contrary,the frequencies of the ε3 allele and ε3/ε3 genotype were lower in IBD patients as compared to controls,suggesting a protective effect of APOE ε3 for IBD.The prevalence of the ε4 allele was also higher in the patient group compared to controls,suggesting that the ε4 allele may also increase the risk of IBD.Our results also indicated that the APOE ε4 allele was associated with an early age of IBD onset.No effect of gender or type of IBD(familial or sporadic) on the frequency distribution of APOE alleles and genotypes was noticed in this study.CONCLUSION:APOE polymorphism is associated with risk of developing IBD and early age of onset in Saudi patients,though further studies with a large-size population are warranted. | Ebtissam Saleh Al-Meghaiseeb Mulfi Mubarak Al-Otaibi Abdulrahman Al-Robayan Reem Al-Amro Ahmd Saad Al-Malki Misbahul Arfin Abdulrahman K Al-Asmari | 2015 | World Journal of Gastroenterology2015，21，3： | 1 |
| 12 | New vinyl ester resins based on rosin for coating applications显示文摘 | Ayman M Atta Shymaa M E1-Saeed Reem K Farag | 2006 | React Funct Polym2006，66，： | 1 |
| 13 | Synthesis of unsaturated polyester resins based on rosin acrylic acid adduct for coating application显示文摘 | M Ayman M Ashraf K Reem | 2007 | 67(6):549-5632007，67，6： | 1 |
| 14 | Lateral-torsional coupling in earthquake response of flame buildings 显示文摘 | Hejal Reem Chopra A K | 1989 | Journal of Structural Engineering1989，115，4： | 1 |
| 15 | Synthesis of unsaturated polyester resin based on rosin acrylic acid adduct for coating applications显示文摘 | Ayman M Atta Ashraf M Elsaeed Reem K Farag | 2007 | Reactive & Functional Polymers2007，67，6： | 1 |
| 16 | Synthesis and characterization of novel pour point depressants based on maleic anhydride-alkyl acrylates terpolymers显示文摘 | Rasha A El-Ghazawy Reem K Farag | 2010 | Journal of Applied Polymer Science2010，115，1： | 1 |
| 17 | 血浆置换和糖皮质激素治疗抗中性粒细胞胞质抗体相关性血管炎:临床实践指南显示文摘对于抗中性粒细胞胞质抗体(antineutrophil cytoplasmic antibody,ANCA)相关性血管炎(ANCA-associated vasculitis,AAV)患者,血浆置换的作用是什么?接受治疗前6个月糖皮质激素的最佳剂量是多少?一项新发表的随机对照试验(randomised controlled trial,RCT)引起本次指南的制订。 | 曾力楠 Michael Walsh Gordon H Guyatt Reed A C Siemieniuk David Collister Michelle Booth Paul Brown Lesha Farrar Mark Farrar Tracy Firth Lynn A Fussner Karin Kilian Mark A Little Thomas A Mavrakanas Reem A Mustafa Maryam Piram Lisa K Stamp 肖瑛琪 Lyubov Lytyn Thomas Agoritsas Per O Vandvik Alfred Mahr 刘峥(译) 徐佩佩(译) 张伶俐(校) | 2022 | 英国医学杂志中文版2022，25，12： | 1 |
| 18 | SJES14121200025593显示文摘 | Eric Lawitz Mark S Sulkowski Reem Ghalib Maribel Rodriguez-Torres Zobair M Younossi Ana Corregidor Edwin DeJesus Brian Pearlman Mordechai Rabinovitz Norman Gitlin Joseph K Lim Paul J Pockros John D Scott Bart Fevery Tom Lambrecht Sivi Ouwerkerk-Mahadevan | 2014 | The Lancet . 2014 (9956)2014，，： | 1 |
| 19 | Daclatasvir for previously untreated chronic hepatitis C genotype-1 infection: a randomised, parallel-group, double-blind, placebo-controlled, dose-finding, phase 2a trial显示文摘 | Stanislas Pol Reem H Ghalib Vinod K Rustgi Claudia Martorell Greg T Everson Harvey A Tatum Christophe Hézode Joseph K Lim Jean-Pierre Bronowicki Gary A Abrams Norbert Br?u David W Morris Paul J Thuluvath Robert W Reindollar Philip D Yin Ulysses Diva Rober | 2012 | The Lancet Infectious Diseases2012，，9： | 1 |
| 20 | SJES14121200025593显示文摘 | Eric Lawitz Mark S Sulkowski Reem Ghalib Maribel Rodriguez-Torres Zobair M Younossi Ana Corregidor Edwin DeJesus Brian Pearlman Mordechai Rabinovitz Norman Gitlin Joseph K Lim Paul J Pockros John D Scott Bart Fevery Tom Lambrecht Sivi Ouwerkerk-Mahadevan | 2014 | 2014 (9956)2014，，9956： | 1 |
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