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| 1 | Helicobacter pylori eradication and metachronous gastric cancer after endoscopic mucosal resection of early gastric cancer显示文摘 | S.NAKAGAWA M.ASAKA M.KATO T.NAKAMURA C.KATO T.FUJIOKA M.TATSUTA K.KEIDA S.TERAO S.TAKAHASHI N.UEMURA T.KATO N.AOYAMA D.SAITO M.SUZUKI A.IMAMURA K.SATO H.MIWA H.NOMURA M.KAISE S.OOHARA T.KAWAI K.URABE N.SAKAKI S.ITO Y.NODA A.YANAKA K.KUSUGAMI H.GOTO T.FURU | 2007 | Alimentary Pharmacology & Therapeutics2007，，： | 2 |
| 2 | Signal distortion and noise in AM-SCM transmission systems employing the feedforward linearized MQW-EA external modulator显示文摘 | T.Iwai K.Sato K.Suto | | 0，，08： | 1 |
| 3 | Comparative functional genomics identifies an iron-limited bottleneck in a Saccharomyces cerevisiae strain with a cytosolic-localized isobutanol pathway显示文摘Metabolic engineering strategies have been successfully implemented to improve the production of isobutanol,a next-generation biofuel,in Saccharomyces cerevisiae.Here,we explore how two of these strategies,pathway re-localization and redox cofactor-balancing,affect the performance and physiology of isobutanol producing strains.We equipped yeast with isobutanol cassettes which had either a mitochondrial or cytosolic localized isobutanol pathway and used either a redox-imbalanced(NADPH-dependent)or redox-balanced(NADH-dependent)ketol-acid reductoisomerase enzyme.We then conducted transcriptomic,proteomic and metabolomic analyses to elucidate molecular differences between the engineered strains.Pathway localization had a large effect on isobutanol production with the strain expressing the mitochondrial-localized enzymes producing 3.8-fold more isobutanol than strains expressing the cytosolic enzymes.Cofactor-balancing did not improve isobutanol titers and instead the strain with the redox-imbalanced pathway produced 1.5-fold more isobutanol than the balanced version,albeit at low overall pathway flux.Functional genomic analyses suggested that the poor performances of the cytosolic pathway strains were in part due to a shortage in cytosolic Fe-S clusters,which are required cofactors for the dihydroxyacid dehydratase enzyme.We then demonstrated that this cofactor limitation may be partially recovered by disrupting iron homeostasis with a fra2 mutation,thereby increasing cellular iron levels.The resulting isobutanol titer of the fra2 null strain harboring a cytosolic-localized isobutanol pathway outperformed the strain with the mitochondrial-localized pathway by 1.3-fold,demonstrating that both localizations can support flux to isobutanol. | Francesca V.Gambacorta Ellen R.Wagner Tyler B.Jacobson Mary Tremaine Laura K.Muehlbauer Mick A.McGee Justin J.Baerwald Russell L.Wrobel John F.Wolters Mike Place Joshua J.Dietrich Dan Xie Jose Serate Shabda Gajbhiye Lisa Liu Maikayeng Vang-Smith Joshua J.Coon Yaoping Zhang Audrey P.Gasch Daniel Amador-Noguez Chris Todd Hittinger Trey K.Sato Brian F.Pfleger | 2022 | Synthetic and Systems Biotechnology2022，7，2： | 1 |
| 4 | Effects of deformation induced phase transformation and twinning on the mechanical properties of austenitic Fe-Mn-Al alloys显示文摘 | K.Sato M.Ichinose Y.Hirotsu | | 0，，： | 1 |
| 5 | Neuroprotective effects of a combination of dexmedetomidine and hypothermia after incomplete cerebral ischemia in rats显示文摘 | K.SATO T.KIMURA T.NISHIKAWA Y.TOBE Y.MASAKI | 2010 | Acta Anaesthesiologica Scandinavica2010，，3： | 1 |
| 6 | 肾功能不全患者的可逆性甲功低下和血清碘水平升高显示文摘众所周知碘过剩可抑制碘的有机化过程。经甲状腺切除术或^(131)Ⅰ处理的淋巴瘤性甲状腺肿或突眼性甲亢的患者易患碘性粘液水肿。在服用含碘药物的患者中,即使没有任何甲状腺疾患的证据也偶而见到碘诱导甲低症的报道。我们已指出经常摄取海藻也能引起明显的原发性甲低症,组织学上被证实为淋巴瘤性甲状腺炎。碘诱导的甲低症在日本并不罕见,平均碘摄取约为0.1~20mg/天。 | K.Sato 毕永江 | 1993 | 地方病译丛1993，14，4： | 0 |
| 7 | 一个新的喹诺酮,左旋氧氟沙星(DR-3355)在体外的抗分支杆菌活性显示文摘目的:检查左旋氧氟沙星在体外的抗分支杆菌活性。设计:用7H11培养基,以琼脂稀释方法测左旋氧氟沙星对不同种的分支杆菌的最小抑制浓度(MIC),并与氧氟沙星比较。左旋氧氟沙星对于被小鼠腹腔巨噬细胞吞食的结核分支杆菌和胞内分支杆菌的抗微生物活性是以菌落形成单位(CFU)的减少来衡量的。结果:左旋氧氟沙星抗结核分支杆菌、堪萨斯分支杆菌、海鱼分支杆菌、瘰疬分支杆菌、鸟分支杆菌、胞内分支杆菌、偶然分支杆菌和龟分支杆菌的MIC比氧氟沙星的MIC低2到4倍。左旋氧氟沙星减少巨噬细胞内CFU的效果高于氧氟沙星。结论:左旋氧氟沙星比氧氟沙星具有更强的体外抗分支杆菌活性。 | H.Saito K.Sato H.Tomioka S.Dekio 雷海鹏 | 1996 | 国际结核病与肺部疾病杂志1996，0，3： | 0 |
| 8 | On-line Time Differential Perturbed Angular Correlation With Light Probe Nucleus ^(19)F显示文摘1 IntroductionThe time differential perturbed angular correlation(TDPAC) has been known for about 50 years. So far, no on-line TDPAC(TDPACOL) has been performed because of mother nuclei all having a rather long lifetime. In addition, almost all TDPAC experiments have been conducted using probe nuclei with a mass heavier than 40.The present work is motivated to develop a TDPACOL technique with light probe nuclei. The key point for it is to have short-lived mother nuclei with a lifetime of, say, several ten seconds. We have found a suitable mother nucleus 19O having a half-life of 26.9 s and decaying to the daughter | T.Minamisono K.Matsuta M.Fukuda M.Mihara WANGZhi-qiang K.Sato H.Akai | 2001 | Annual Report of China Institute of Atomic Energy2001，，0： | 0 |
| 9 | 整体低压涡轮转子轴锻件的制造显示文摘本文涉及核电站用整体低压涡轮转子锻件的制造成就和日本铸锻件公司应用于生产的先进技术。这种发货重量达110t的转子锻件是由410t钢锭制造的大型锻件,而获得的性能满足于质量要求。 | K.Sato Y.Ohno K.Soeda K.Nakata 懦夫 | 1986 | 大型铸锻件1986，，2： | 0 |
| 10 | Spectroscopic Measurement of Shock Waves in an Arcjet Plasma Expanding Through a Conical Nozzle显示文摘A diamond-shaped shock wave was created in a helium arcjet plasma. Visi- ble/ultraviolet emission spectroscopy was used to investigate the condition for the formation of stable shocks and to determine characteristics of the plasma. Dependence of the position of the shock front on the gas pressure in the expansion region was investigated. It was found that the shock wave arises from the collision of plasma particles and residual neutral atoms in that region. Continuum and line spectra of neutral helium were measured, from which the electron temper- atures were derived. The electron density was deduced from the Inglis-Teller limit of the He I 2p 3 P-3d 3 D series. The temperature and density were found to have almost constant values of 0.2 eV and 8.5×10 13 cm 3 , respectively, across the shock front. | K.KOZUE G.KUMAKAWA S.NAMBA T.ENDO K.TAKIYAMA K.SATO N.TAMURA | 2013 | Plasma Science and Technology2013，15，2： | 0 |
| 11 | A HREELS study of the adsorption of formic acid on slightly oxidized Nb(110) surface显示文摘An investigation has been made on the adsorption and decomposition of formic acid on slightly oxidized Nb(110) surface (0/Nb atom ratio = 0.2) using high resolution electron energy loss spectroscopy (HREELS),and a corresponding surface reaction mode is given.At 140 K,formic acid of low exposure on such an Nb(110) surface decomposed to formate,which bonded on Nb in monodentate configuration,simultaneously some formate decomposed to CO,which adsorbed on the surface.Formic acid multilayers formed when the exposure was high.While the temperature was increased to above 190 K,multilayer formic acid desorbed,and the surface was covered with mon-odentate-bonded formate and CO.In the temperature range of 250-300 K,chemisorbed formate changed from monodentate configuration into bridging configuration and CO molecules disappeared.The decomposition of formate at higher temperatures led to the oxidation of Nb.The formate formed in the high exposure case was so stable that it did not decompose even the temperature | 汪寅生 魏绪明 田志坚 翟润生 T.Ushikubo K.Sato 庄叔贤 | 1997 | Science China Chemistry1997，40，1： | 0 |
| 12 | 世界最大容量8kV/3.6kA光控晶闸管显示文摘为了适应高压直流输电和反并系统中电力变流器的需要,三菱电子公司开发了152.4mm硅片8 kV/3.6 kA光控晶闸管(LTT)。这种新设计的器件比以前101.6 mmLTT功率控制容量增加了1倍,同时缓和器件容量增大而出现各种问题。 | K.Sato 黄慧 | 1997 | 大功率变流技术1997，0，3： | 0 |
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