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| 1 | Removal of diminutive colorectal polyps: A prospective randomized clinical trial between cold snare polypectomy and hot forceps biopsy显示文摘AIM To compare the efficacy and safety of cold snare polypectomy(CSP) and hot forceps biopsy(HFB) for diminutive colorectal polyps.METHODS This prospective, randomized single-center clinical trial included consecutive patients ≥ 20 years of age with diminutive colorectal polyps 3-5 mm from December 2014 to October 2015. The primary outcome measures were en-bloc resection(endoscopic evaluation) and complete resection rates(pathological evaluation). The secondary outcome measures were the immediate bleeding or immediate perforation rate after polypectomy, delayed bleeding or delayed perforation rate after polypectomy, use of clipping for bleeding or perforation, and polyp retrieval rate. Prophylactic clipping after polyp removal wasn't routinely performed.RESULTS Two hundred eight patients were randomized into the CSP(102), HFB(106) and 283 polyps were evaluated(CSP: 148, HFB: 135). The en-bloc resection rate was significantly higher with CSP than with HFB [99.3%(147/148) vs 80.0%(108/135), P < 0.0001]. The complete resection rate was significantly higher with CSP than with HFB [80.4%(119/148) vs 47.4%(64/135), P < 0.0001]. The immediate bleeding rate was similar between the groups [8.6%(13/148) vs 8.1%(11/135), P = 1.000], and endoscopic hemostasis with hemoclips was successful in all cases. No cases of perforation or delayed bleeding occurred. The rate of severe tissue injury to the pathological specimen was higher HFB than CSP [52.6%(71/135) vs 1.3%(2/148), P < 0.0001]. Polyp retrieval failure was encountered CSP(7), HFB(2).CONCLUSION CSP is more effective than HFB for resecting diminutive polyps. Further long-term follow-up study is required. | Yoriaki Komeda Hiroshi Kashida Toshiharu Sakurai George Tribonias Kazuki Okamoto Masashi Kono Mitsunari Yamada Teppei Adachi Hiromasa Mine Tomoyuki Nagai Yutaka Asakuma Satoru Hagiwara Shigenaga Matsui Tomohiro Watanabe Masayuki Kitano Takaaki Chikugo Yasutaka Chiba Masatoshi Kudo | 2017 | World Journal of Gastroenterology2017,23,2: | 20 |
| 2 | Risk factors for local recurrence and appropriate surveillance interval after endoscopic resection显示文摘BACKGROUND Risk factors for local recurrence after polypectomy, endoscopic mucosal resection(EMR), and endoscopic submucosal dissection(ESD) have not been identified.Additionally, the appropriate interval for endoscopic surveillance of colorectal tumors at high-risk of local recurrence has not been established.AIM To clarify the clinicopathological characteristics of recurrent lesions after endoscopic colorectal tumor resection and determine the appropriate interval.METHODS Three hundred and sixty patients(1412 colorectal tumors) who underwent polypectomy, EMR, or ESD and received endoscopic surveillance subsequently for more than one year to detect local recurrence were enrolled in this study. The clinicopathological factors associated with local recurrence were determined via univariate and multivariate analyses.RESULTS Local recurrence was observed in 31 of 360(8.6%) patients [31 of 1412(2.2%)lesions] after colorectal tumor resection. Piecemeal resection, tumor size of more than 2 cm, and the presence of villous components were associated with colorectal tumor recurrence after endoscopic resection. Of these three factors, the piecemeal resection procedure was identified as an independent risk factor for recurrence. Colorectal tumors resected into more than five pieces were associated with a high risk of recurrence since the average period from resection torecurrence in these cases was approximately 3 mo. The period to recurrence in cases resected into more than 5 pieces was much shorter than that in those resected into less than 4 pieces(3.8 ± 1.9 mo vs 7.9 ± 5.0 mo, P < 0.05).CONCLUSION Local recurrence of endoscopically treated colorectal tumors depends upon the outcome of first endoscopic procedure. Piecemeal resection was the only significant risk factor associated with local recurrence after endoscopic resection. | Yoriaki Komeda Tomohiro Watanabe Toshiharu Sakurai Masashi Kono Kazuki Okamoto Tomoyuki Nagai Mamoru Takenaka Satoru Hagiwara Shigenaga Matsui Naoshi Nishida Naoko Tsuji Hiroshi Kashida Masatoshi Kudo | 2019 | World Journal of Gastroenterology2019,25,12: | 4 |
| 3 | Laparoscopic and endoscopic cooperative surgery for duodenal tumor resection显示文摘 | Fumitoshi Hirokawa Michihiro Hayashi Yoshiharu Miyamoto Mitsuhiro Asakuma Tetsunosuke Shimizu Koji Komeda Yoshihiro Inoue Eiji Umegaki Kazuhisa Uchiyama | 2014 | Endoscopy2014,,: | 3 |
| 4 | Postoperative detection of alpha-fetoprotein mRNA in blood as a predictor for metastatic re-currence ofhepatocel ular carcinoma显示文摘 | Minata M Nishida N Komeda T | | 0,,04: | 1 |
| 5 | Early systolic mitral leaflet 'loitering' during acute ischemic mitral regurgitation显示文摘 | Komeda M Daughters GT | 1998 | J Thorac Cardiovasc Surg1998,116,: | 1 |
| 6 | Plasma progesterone concentrations during estrous cycle,pregnancy,and lactation in the chinese hamster, cricetulus griceus显示文摘 | Sato T Komeda K Shirama K | 1984 | Jikken Dobuteu1984,33,4: | 1 |
| 7 | Comparative histopathology of radial artery versus internal thoracic artery and risk factors for development of intimal hyperplasia and atherosclerosis显示文摘 | Ruengsakulrach P Sinclair R Komeda M | 1999 | Circulation1999,100,: | 1 |
| 8 | Sensitive detection of circulating hepatocellalar carcinoma cells in peripheral venous blood 显示文摘 | Komeda F Fukuda Y Sando T | 1995 | Cancer1995,75,9: | 1 |
| 9 | Regenerative medicine with the sus- tained release system of basic fibroblast growth factor 显示文摘 | Arai Y Marui A Komeda M | 2006 | Nippon Rinsho2006,64,11: | 1 |
| 10 | Clinicopathological analysis of recurrence patterns and prognostic factors for survival after hepatectomy for colorectal liver metastasis 显示文摘 | Hayashi M Inoue Y Komeda K | 2010 | BMC Surg2010,10,: | 1 |
| 11 | Prevascularization with gelatin microspheres containing basic fibroblast growth factor enhances the benefits of cardiomyocyte transplantation显示文摘 | Yutaka Sakakibara Kazunobu Nishimura Keiichi Tambara Masaya Yamamoto Fanglin Lu Yasuhiko Tabata Masashi Komeda | 2002 | The Journal of Thoracic and Cardiovascular Surgery2002,,1: | 1 |
| 12 | Surgical treatment of aortic root abscess 显示文摘 | David TE Komeda M Borfman PR | 1989 | Cirulation1989,80,31: | 1 |
| 13 | Amplification and overexpression of the cyclinD1gene in aggressive human hepatocellular carcinoma显示文摘 | Nishida N Fukuda Y Komeda T | 1994 | Cancer Res1994,54,12: | 1 |
| 14 | Mycoplasma genitalium in the cervices of Japanese women显示文摘 | Uno M Deguchi T Komeda H | 1997 | Sex Transm Dis1997,24,2: | 1 |
| 15 | A male-associated DNA sequence in a dioecious plant,Cannabis sativa L显示文摘 | Sakamoto K Shimomura K Komeda Y | | 0,,08: | 1 |
| 16 | Next-generation anticancer metallo- drugs显示文摘 | Komeda S Casini A | 2012 | Curr Top Med Chem2012,12,3: | 1 |
| 17 | Analysis of tissue-specific expression of Arabidopsis thaliana Hsp90-family gene HSP81 显示文摘 | Yabe N Takahashi T Komeda Y | 1994 | Plant and Cell Physiology1994,,: | 1 |
| 18 | Analysis of tissue-specific expression of Arabidopsis thaliana HSP90-family gene HSP81显示文摘 | Yabe N Takahshi T Komeda Y | 1994 | Plant Cell Physiology1994,35,: | 1 |
| 19 | Gene analysis and trehalose-producing enzymes from the hypertemophilic archaeum Sulfolobus solfatariCUS KMI显示文摘 | Kobayashi K Komeda T Miura Y | 1996 | Biosci Biotech Biochem1996,60,10: | 1 |
| 20 | Insulin-like Growth Factor-1 Enhances the Efficacy of Myoblast Transplantation With Its Multiple Functions in the Chronic Myocardial Infarction Rat Model显示文摘 | Naoki Kanemitsu Keiichi Tambara Goditha Upul Premaratne Yu Kimura Shinji Tomita Teruhisa Kawamura Koji Hasegawa Yasuhiko Tabata Masashi Komeda | 2006 | Journal of Heart and Lung Transplantation2006,,10: | 1 |