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| 1 | Predictive value of C-reactive protein/albumin ratio in acute pancreatitis显示文摘BACKGROUND:Serum C-reactive protein(CRP) increases and albumin decreases in patients with inflammation and infection.However,their role in patients with acute pancreatitis is not clear.The present study was to investigate the predictive significance of the CRP/albumin ratio for the prognosis and mortality in acute pancreatitis patients.METHODS:This study was performed retrospectively with 192 acute pancreatitis patients between January 2002 and June 2015.Ranson scores,Atlanta classification and CRP/albumin ratios of the patients were calculated.RESULTS:The CRP/albumin ratio was higher in deceased patients compared to survivors.The CRP/albumin ratio was positively correlated with Ranson score and Atlanta classification in particular and with important prognostic markers such as hospitalization time,CRP and erythrocyte sedimentation rate.In addition to the CRP/albumin ratio,necrotizing pancreatitis type,moderately severe and severe Atlanta classification,and total Ranson score were independent risk factors of mortality.It was found that an increase of 1 unit in the CRP/albumin ratio resulted in an increase of 1.52 times in mortality risk.A prediction value about CRP/albumin ratio >16.28 was found to be a significant marker in predicting mortality with 92.1% sensitivity and 58.0% specificity.It was seen that Ranson and Atlanta classification were higher in patients with CRP/albumin ratio >16.28 compared with those with CRP/albumin ratio ≤16.28.Patients with CRP/albumin ratio >16.28 had a 19.3 times higher chance of death.CONCLUSION:The CRP/albumin ratio is a novel but promising,easy-to-measure,repeatable,non-invasive inflammationbased prognostic score in acute pancreatitis. | Mustafa Kaplan Ihsan Ates Muhammed Yener Akpinar Mahmut Yuksel Ufuk Baris Kuzu Sabite Kacar Orhan Coskun Ertugrul Kayacetin | 2017 | Hepatobiliary & Pancreatic Diseases International2017，16，4： | 53 |
| 2 | Enteral glutamine pretreatment does not decrease plasma endotoxin level induced by ischemia-reperfusion injury in rats显示文摘AIM:To investigate whether oral glutamine pretreatment prevents impairment of intestinal mucosal integrity during ischemia-reperfusion (I/R) in rats. METHODS: The study was performed as two series with 40 rats in each. Each series of animals was divided into four groups. The first group was used as a control. Animals in the second group were only pretreated with oral glutamine, 1 g/kg for 4 d. The third group received a normal diet, and underwent intestinal I/R, while the fourth group was pretreated with oral glutamine in the same way, and underwent intestinal I/R. Intestinal mucosal permeability to 51Cr-labeled EDTA was measured in urine in the first series of animals. In the second series, histopathological changes in intestinal tissue and plasma endotoxin levels were evaluated. RESULTS: Intestinal I/R produced a significant increase in intestinal permeability, plasma endotoxin level and worsened histopathological alterations. After intestinal I/R, permeability was significantly lower in glutamine- treated rats compared to those which received a normal diet. However, no significant change was observed in plasma endotoxin levels or histopathological findings. CONCLUSION: Although glutamine pretreatment seems to be protective of intestinal integrity, upon I/R injury, such an effect was not observable in the histopathological changes or plasma endotoxin level. | Arda Demirkan Erkin Orazakunov Berna Sava■ M Ayhan Kuzu Mehmet Melli | 2008 | World Journal of Gastroenterology2008，14，3： | 2 |
| 3 | Obstructive jaundice promotes bacterial translocation in humans显示文摘 | Kuzu MA Kale IT Col C | 2006 | Hepatogastroenterology2006，46，28： | 1 |
| 4 | Dynamic planning approach to automated Web service composition 显示文摘 | KUZU M CICEKLI N K | 2012 | Applied Intelligence2012，36，1： | 1 |
| 5 | Forecasting air traffic volumes using smoothing techniques显示文摘 | ONDER E KUZU S | 2014 | Journal of Aeronautics and Space Technologies2014，7，1： | 1 |
| 6 | Polymicrobial sepsis induces organ changes due to granulocyte adhesion in a murine two hit model of trauma显示文摘 | van Griensven M Kuzu M Breddin M | 2002 | Exp Toxicol Pathol2002，54，： | 1 |
| 7 | Perineal and pelvic anatomy of extralevator abdominoperineal excision for rectal cancer:cadaveric dissection显示文摘 | Afar Hi Kuzu MA | 2011 | Dis Colon Rectum2011，54，： | 1 |
| 8 | Preoperative nutritional risk assessment in predieting postoperative outcome in patients under- going major surgery显示文摘 | Kuzu MA Terziolu H Gent V | 2006 | World J Surg2006，30，3： | 1 |
| 9 | Relationship between maternal thyroid hormones and the biochemical markers of the first trimester aneuploidy screening显示文摘 | Hakan Aytan Ahmet C. Caliskan Fazl? Demirturk Semsettin Sahin Filiz Erdogan Zehra Kuzu | 2013 | Archives of Gynecology and Obstetrics2013，，6： | 1 |
| 10 | Heterogeneity of vascular endothelial cells with relevance to diagnosis of vasculartumors显示文摘 | Kuzu I Bicknell R Harris A L | 1992 | J Clin Pathol1992，45，2： | 1 |
| 11 | Polymicrobial sepsis induces organ changes due to granulocyte adhesion in a murine two hit model of trauma显示文摘 | van Griensven M Kuzu M Breddin M | 2002 | Exp Toxicol Pathol2002，54，3： | 1 |
| 12 | Perineal and pelvic anatomy of extralevator abdominoperineal excision for rectal cancer:cadaveric dissection显示文摘 | A(c)ar H(I) Kuzu MA | | 0，，： | 1 |
| 13 | Multidentate ligand systems featuring dual functionality显示文摘 | KUZU I KRUMMENACHER I MEYER J | 2008 | Dalton Trana2008，，43： | 1 |
| 14 | Mean particle size prediction in rock blast fragmentation using neural networks 显示文摘 | KULATILAKE P H S W WU Q HUDAVERDI T KUZU C | 2010 | Engineering Geology2010，114，34： | 1 |
| 15 | The usefulness of chromoendoscopy with methylene blue in Barrett’s metaplasia and early esophageal carcinoma显示文摘 | N. Ormeci B. Savas S. Coban M. Palab?y?ko?lu A. Ensari I. Kuzu N. Kursun | 2008 | Surgical Endoscopy2008，，3： | 1 |
| 16 | Preoperative nutritional risk assessment in predicting postoperative outcome in patients undergoing major surgery 显示文摘 | Kuzu MA Terzioglu H Genc V | 2006 | World J Surg2006，30，3： | 1 |
| 17 | Admission lactate level and the APACHE II score are the most useful predictors of prognosis following torso trauma显示文摘 | Aslar AK Kuzu MA Elhan AH | 2004 | Injury2004，35，8： | 1 |
| 18 | The relationship between low maternal serum 25-hydroxyvitamin D levels and gestational diabetes mellitus according to the severity of 25-hydroxyvitamin D deficiency显示文摘 | Zuhur SS Erol RS Kuzu I | 2013 | Clinics(Sao Paulo)2013，68，： | 1 |
| 19 | The Levels of Ghrelin, Leptin, TNF- α , and IL-6 in Liver Cirrhosis and Hepatocellular Carcinoma due to HBV and HDV Infection显示文摘 | Huseyin Ataseven Ibrahim Halil Bahcecioglu Nalan Kuzu Mehmet Yalniz Selman Celebi Ahmet Erensoy Bilal Ustundag | 2006 | Mediators of Inflammation2006，，： | 1 |
| 20 | Effect of 3-tesla magnetic resonance imaging on various pressure programmable shunt valves 显示文摘 | Inoue T Kuzu Y Ogasawara K | 2005 | J Neurosurg2005，103，2： | 1 |
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