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| 1 | Nonlinear controller designs for thermal management in PCR amplificafion显示文摘 | Jiang Jingbo Kaigala G V Marquez H J | | 0，，05： | 1 |
| 2 | An inexpensive and portable microchip-based platform for integrated RT-PCR and capillary electrophoresis 显示文摘 | Kaigala G V Hoang V N Stickel A | 2008 | Analyst2008，133，3： | 1 |
| 3 | Rapid micro-immunohistochemistry显示文摘We present a new and versatile implementation of rapid and localized immunohistochemical staining of tissue sections.Immunohistochemistry(IHC)comprises a sequence of specific biochemical reactions and allows the detection of specific proteins in tissue sections.For the rapid implementation of IHC,we fabricated horizontally oriented microfluidic probes(MFPs)with functionally designed apertures to enable square and circular footprints,which we employ to locally expose a tissue to time-optimized sequences of different biochemicals.We show that the two main incubation steps of IHC protocols can be performed on MDAMB468-1510A cell block sections in less than 30 min,compared to incubation times of an hour or more in standard protocols.IHC analysis on the timescale of tens of minutes could potentially be applied during surgery,enabling clinicians to react in more dynamically and efficiently.Furthermore,this rapid IHC implementation along with conservative tissue usage has strong potential for the implementation of multiplexed assays,allowing the exploration of optimal assay conditions with a small amount of tissue to ensure high-quality staining results for the remainder of the sample. | Robert D.Lovchik David Taylor Govind Kaigala | 2020 | Microsystems & Nanoengineering2020，6，1： | 0 |
| 4 | Dynamic control of high-voltage actuator arrays by light-pattern projection on photoconductive switches显示文摘The ability to control high-voltage actuator arrays relies, to date, on expensive microelectronic processes or on individual wiring of each actuator to a single off-chip high-voltage switch. Here we present an alternative approach that uses on-chip photoconductive switches together with a light projection system to individually address high-voltage actuators. Each actuator is connected to one or more switches that are nominally OFF unless turned ON using direct light illumination. We selected hydrogenated amorphous silicon (a-Si:H) as our photoconductive material, and we provide a complete characterization of its light to dark conductance, breakdown field, and spectral response. The resulting switches are very robust, and we provide full details of their fabrication processes. We demonstrate that the switches can be integrated into different architectures to support both AC and DC-driven actuators and provide engineering guidelines for their functional design. To demonstrate the versatility of our approach, we demonstrate the use of the photoconductive switches in two distinctly different applications—control of µm-sized gate electrodes for patterning flow fields in a microfluidic chamber and control of cm-sized electrostatic actuators for creating mechanical deformations for haptic displays. | Vesna Bacheva Amir Firouzeh Edouard Leroy Aiste Balciunaite Diana Davila Israel Gabay Federico Paratore Moran Bercovici Herbert Shea Govind Kaigala | 2023 | Microsystems & Nanoengineering2023，9，3： | 0 |
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