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| 1 | Neuroprotective effects of daidzein on focal cerebral ischemia injury in rats显示文摘Daidzein, a plant extract, has antioxidant activity. It is hypothesized, in this study, that daidzein exhibits neuroprotective effects on cerebral ischemia. Rat models of middle cerebral artery occlusion were intraperitoneally administered daidzein. Biochemical and immunohistochemical tests showed that superoxide dismutase and nuclear respiratory factor 1 expression levels in the brain tissue decreased after ischemia and they increased obviously after daidzein administration; malondialdehyde level and apoptosis-related cysteine peptidase caspase-3 and caspase-9 immunoreactivity in the brain tissue increased after ischemia and they decreased obviously after daidzein administration. Hematoxylin-eosin staining and luxol fast blue staining results showed that intraperitoneal administration of daidzein markedly alleviated neuronal damage in the ischemic brain tissue. These findings suggest that daidzein exhibits neuroprotective effects on ischemic brain tissue by decreasing oxygen free radical production, which validates the aforementioned hypothesis. | Adem Bozkurt Aras Mustafa Guven Tar?k Akman Adile Ozkan Halil Murat Sen Ugur Duz Y?ld?ray Kalkan Coskun Silan Murat Cosar | 2015 | Neural Regeneration Research2015，10，1： | 4 |
| 2 | Syringaldehyde exerts neuroprotective effect on cerebral ischemia injury in rats through anti-oxidative and anti-apoptotic properties显示文摘There are few studies on the neuroprotective effects of syringaldehyde in a rat model of cerebral ischemia. The study aimed to elucidate the mechanisms underlying the neuroprotective effects of syringaldehyde on ischemic brain cells. Rat models of cerebral ischemia were intraperitoneally administered syringaldehyde. At 6 and 24 hours after syringaldehyde administration, cell damage in the brain of cerebral ischemia rats was obviously reduced, superoxide dismutase activity and nuclear respiratory factor 1 expression in the brain tissue were markedly increased, malondiadehyde level was obviously decreased, apoptosis-related cysteine peptidase caspase-3 and-9 immunoreactivity was obviously decreased, and neurological function was markedly improved. These findings suggest that syringaldehyde exerts neuroprotective effects on cerebral ischemia injury through anti-oxidation and anti-apoptosis. | Aras Adem Bozkurt Guven Mustafa Akman Tar?k Ozkan Adile Sen Halil Murat K?l?coglu Mesut Kalkan Y?ld?ray Silan Coskun Cosar Murat | 2014 | Neural Regeneration Research2014，9，21： | 2 |
| 3 | A rapid-response,high-sensitivity nanophase humidity sensor for respiratory monitoring 显示文摘 | Kalkan A K Li Handong O'Brien C J | 2004 | Electron Device Letters IEEE2004，25，8： | 1 |
| 4 | Emergency operation indications in emergency medicine clinic(model of emergency medicine in Turkey) 显示文摘 | Cander B Kalkan E Girisgin S | 2006 | Adv Ther2006，23，2： | 1 |
| 5 | Evaluation of two post core systems using two different methods( fracture strength test and a finite elemental stress analysis ) 显示文摘 | Eskitaseioglu G Bell S Kalkan M | 2002 | J Endod2002，28，9： | 1 |
| 6 | Accuracy of endoscopic ultrasound-guided fine needle aspiration cytology on the differentiation of malignant and benign pancreatic cystic lesions : a single-center experience显示文摘 | Oguz D Oztas E Kalkan IH | 2013 | J Dig Dis2013，14，3： | 1 |
| 7 | The relation of platelet- lymphocyte ratio and coronary collateral circulation in patients with stable angina pectoris and chronic total occlusion 显示文摘 | Aear G Kalkan ME Avci A | 2015 | Clin Appl Thromb Hemost2015，21，5： | 1 |
| 8 | Evaluation of two post core systems using two different methods (fracture strength test and a finite elemental stress analysis) 显示文摘 | Eskitaseioglu G Belli S Kalkan M | 2002 | J Endod2002，28，9： | 1 |
| 9 | Low incidence of colorectal dysplasia and cancer among patients with ulcerative colitis: A Turkish referral centre study显示文摘 | Murat Kekilli Ulku Dagli Ismail Hakki Kalkan Bilge Tunc Selcuk Disibeyaz Aysel Ulker Burhan Sahin | 2010 | Scandinavian Journal of Gastroenterology2010，，4： | 1 |
| 10 | Modification of clayey soils using scrap tire rubber and synthetic fibers 显示文摘 | Akbulut S Arasan S Kalkan E | 2007 | Ap- plied Clay Science2007，38，12： | 1 |
| 11 | Effects of fling step and forward directivity on seismic response of buildings 显示文摘 | Kalkan E Kunnath S K | 2006 | Earthquake Spectra2006，22，2： | 1 |
| 12 | Evalua- tion of Biological Activated Carbon (BAC) process in wastewater treatment secondary effluent for reclamation pur- poses显示文摘 | KALKAN C YAPSAKLI K MERTOGLU B | 2011 | Desalination2011，265，123： | 1 |
| 13 | Influence of silica fume on the desiccation cracks of compacted clayey soils显示文摘 | KALKAN E | | 0，，： | 1 |
| 14 | Meanplatelet volume is associated with aortic intima-mediathickness in patients without clinical manifestation ofatherosclerotic cardiovascular disease 显示文摘 | YUksel Kalkan G Giir M Baykan A 0 ef al | 2014 | AnadoluKardiyol Derg2014，15，10： | 1 |
| 15 | Low incidence of colorectal dysplasia and cancer among patients with ulcerative colitis: A Turkish referral centre study显示文摘 | Murat Kekilli Ulku Dagli Ismail Hakki Kalkan Bilge Tunc Selcuk Disibeyaz Aysel Ulker Burhan Sahin | 2010 | Scandinavian Journal of Gastroenterology2010，，4： | 1 |
| 16 | Removal of copper from aqueous solution using red mud显示文摘 | Hayrunnisa Nadaroglu Ekrem Kalkan Nazan Demir | 2010 | Desalination2010，251，： | 1 |
| 17 | Serum interleukin-6 levels correlate with malnutrition and survival in patients with advanced non-small cell lung cancer 显示文摘 | Songtlr N Kuru B Kalkan F | 2004 | Tumori2004，90，2： | 1 |
| 18 | Comparison of orally exhaled nitric oxide in allergic versus nonallergic rhinitis 显示文摘 | Kalpaklioglu AF Kalkan IK | 2012 | Am J Rhinol Allergy2012，26，2： | 1 |
| 19 | Flexural be- havior of RC beams with regular square or circular web openings 显示文摘 | AYKAC B KALKAN I AYKAC S | 2013 | Engineering Structures2013，56，： | 1 |
| 20 | Utilization of red mud as a stabilization material for the preparation of clay liners显示文摘 | Kalkan E | 2006 | Engineering Geology2006，87，： | 1 |
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