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11篇 您的检索式:作者名="Kalluru"
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1Angiogenic peptide hydrogels for treatment of traumatic brain injury显示文摘Traumatic brain injury(TBI)impacts over 3.17 million Americans.Management of hemorrhage and coagulation caused by vascular disruption after TBI is critical for the recovery of patients.Cerebrovascular pathologies play an important role in the underlying mechanisms of TBI.The objective of this study is to evaluate a novel regenerative medicine for the injured tissue after brain injury.We utilized a recently described synthetic growth factor with angiogenic potential to facilitate vascular growth in situ at the injury site.Previous work has shown how this injectable self-assembling peptide-based hydrogel(SAPH)creates a regenerative microenvironment for neovascularization at the injury site.Supramolecular assembly allows for thixotropy;the injectable drug delivery system provides sustained in vivo efficacy.In this study,a moderate blunt injury model was used to cause physical vascular damage and hemorrhage.The angiogenic SAPH was then applied directly on the injured rat brain.At day 7 post-TBI,significantly more blood vessels were observed than the sham and injury control group,as well as activation of VEGF-receptor 2,demonstrating the robust angiogenic response elicited by the angiogenic SAPH.Vascular markers von-Willebrand factor(vWF)andα-smooth muscle actin(α-SMA)showed a concomitant increase with blood vessel density in response to the angiogenic SAPH.Moreover,blood brain barrier integrity and blood coagulation were also examined as the parameters to indicate wound recovery post TBI.Neuronal rescue examination by NeuN and myelin basic protein staining showed that the angiogenic SAPH may provide and neuroprotective benefit in the long-term recovery.Xiaotang Ma Agnieszka Agas Zain Siddiqui KaKyung Kim Patricia Iglesias-Montoro Jagathi Kalluru Vivek Kumar James Haorah 2020Bioactive Materials2020,5,1:3
2Lack of change in urate deposition by dual-energy computed tomography among clinically stable patients with long-standing tophaceous gout:a prospective longitudinal study显示文摘Rajan A Aati O Kalluru R 2013Arthritis Res Ther2013,15,:1
3Tendon involvement in the feet of patients with gout: a dual-energy CT study显示文摘Nicola Dalbeth Ramanamma Kalluru Opetaia Aati Anne Horne Anthony J Doyle Fiona M McQueen 2013Annals of the Rheumatic Diseases2013,,9:1
4First demonstration of gold nanorods-mediated photodynamie thera- peutic destruction of tumors via near infra-red light activation 显示文摘VANKAYALA R HUANG Y K KALLURU P 2014Small2014,10,8:1
5First demonstration of gold nanoreds-mediated photodynamic thera- peutic destruction of tumors via near infra-red light activation 显示文摘VANKAYALA R HUANG Y K KALLURU P 2014Small2014,10,8:1
6An integrated laser Raman optical sensor for fast detection of nitrogen and oxygen in a cryogenic mixture显示文摘Tiwari V S Luanje A T Kalluru R R 0,,04:1
7Goldnanoparticle-based miniaturized laser-induced fluorescence probe for specific DNA hybridization detection:Studies on size-dependent optical properties显示文摘Kim C K Kalluru R R Singh J P 0,,13:1
8Tendon involvement in the feet of patients with gout: a dual-energy CT study 显示文摘Dalbeth N Kalluru R Aati O 2013Ann Rheum Dis2013,72,9:1
9Quantitative structure and retention relationships for gas chromatographic data: application to alkyl pyridines on apolar and polar phases 显示文摘Palagiri Tulasarmna Kalluru Subramanyam Reddy 2006Journal of Molecular Graphics and Modelling2006,25,4:1
10Lack of change in urate dep- osition by dual-energy computed tomography among clinically stable patients with long-standing tophaceous gout a prospec- tive longitudinal study 显示文摘Rajan A Aati O Kalluru R 2013Arthritis Res Ther2013,15,5:1
11Relationship between structural joint damage and urate deposition in gout: a plain radiography and dual-energy CT study显示文摘Dalbeth N Aati O Kalluru R 2014Ann Rheum Dis2014,12,6:1
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