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| 1 | Enhanced gas separation performance of mixed matrix hollow fiber membranes containing post-functionalized S-MIL-53显示文摘Mixed matrix hollow fiber membranes(MMHFMs)filled with metal-organic frameworks(MOFs)have great potential for energy-efficient gas separation processes,but the major hurdle is polymer/MOFs interfacial defects and membrane plasticization.Herein,lab-synthesized MIL-53 was post-functionalized by aminosilane grafting and subsequently incorporated into Ultem~?1000 polymer matrix to fabricate high performance MMHFMs.SEM,DLS,XRD and TGA were performed to characterize silane-modified MIL-53(S-MIL-53)and prepared MMHFMs.Moreover,the effect of MOFs loading was systematically investigated first;then gas separation performance of MMHFMs for pure and mixed gas was evaluated under different pressures.MMHFMs containing post-functionalized S-MIL-53 achieved remarkable gas permeation properties which was better than model predictions.Compared to pure HFMs,CO_2permeance of MMHFM loaded with 15%S-MIL-53 increased by 157%accompanying with 40%increase for CO_2/N_2selectivity,which outperformed the MMHFM filled with naked MIL-53.The pure and mixed gas permeation measurements with elevated feed pressure indicated that incorporation of S-MIL-53 also increased the resistance against CO_2plasticization.This work reveals that post-modified MOFs embedded in MMHFMs facilitate the improvement of gas separation performance and suppression of membrane plasticization. | Haitao Zhu Xingming Jie Lina Wang Guodong Kang Dandan Liu Yiming Cao | 2018 | Journal of Energy Chemistry2018，27，3： | 6 |
| 2 | Antagonism of Protease-Activated Receptor 4 Protects Against Traumatic Brain Injury by Suppressing Neuroinflammation via Inhibition of Tab2/NF-κB Signaling显示文摘Traumatic brain injury(TBI)triggers the activation of the endogenous coagulation mechanism,and a large amount of thrombin is released to curb uncontrollable bleeding through thrombin receptors,also known as protease-activated receptors(PARs).However,thrombin is one of the most critical factors in secondary brain injury.Thus,the PARs may be effective targets against hemorrhagic brain injury.Since the PAR1 antagonist has an increased bleeding risk in clinical practice,PAR4 blockade has been suggested as a more promising treatment.Here,we explored the expression pattern of PAR4 in the brain of mice after TBI,and explored the effect and possible mechanism of BMS-986120(BMS),a novel selective and reversible PAR4 antagonist on secondary brain injury.Treatment with BMS protected against TBI in mice.mRNA-seq analysis,Western blot,and qRT-PCR verification in vitro showed that BMS significantly inhibited thrombin-induced inflammation in astrocytes,and suggested that the Tab2/ERK/NF-κB signaling pathway plays a key role in this process.Our findings provide reliable evidence that blocking PAR4 is a safe and effective intervention for TBI,and suggest that BMS has a potential clinical application in the management of TBI. | Jianing Luo Xun Wu Haixiao Liu Wenxing Cui Wei Guo Kang Guo Hao Guo Kai Tao Fei Li Yingwu Shi Dayun Feng Hao Yan Guodong Gao Yan Qu | 2021 | Neuroscience Bulletin2021，37，2： | 5 |
| 3 | An improved theoretical procedure for the pore-size analysis of activated carbon by gas adsorption显示文摘Amorphous carbon materials play a vital role in adsorbed natural gas(ANG) storage. One of the key issues in the more prevalent use of ANG is the limited adsorption capacity, which is primarily determined by the porosity and surface characteristics of porous materials. To identify suitable adsorbents, we need a reliable computational tool for pore characterization and, subsequently, quantitative prediction of the adsorption behavior. Within the framework of adsorption integral equation(AIE), the pore-size distribution(PSD) is sensitive to the adopted theoretical models and numerical algorithms through isotherm fitting. In recent years, the classical density functional theory(DFT) has emerged as a common choice to describe adsorption isotherms for AIE kernel construction. However,rarely considered is the accuracy of the mean-field approximation(MFA) commonly used in commercial software. In this work, we calibrate four versions of DFT methods with grand canonical Monte Carlo(GCMC) molecular simulation for the adsorption of CH_4 and CO_2 gas in slit pores at 298 K with the pore width varying from 0.65 to 5.00 nm and pressure from 0.2 to 2.0 MPa. It is found that a weighted-density approximation proposed by Yu(WDA-Yu) is more accurate than MFA and other non-local DFT methods. In combination with the trapezoid discretization of AIE, the WDA-Yu method provides a faithful representation of experimental data, with the accuracy and stability improved by 90.0% and 91.2%, respectively, in comparison with the corresponding results from MFA for fitting CO_2 isotherms. In particular, those distributions in the feature pore width range(FPWR)are proved more representative for the pore-size analysis. The new theoretical procedure for pore characterization has also been tested with the methane adsorption capacity in seven activated carbon samples. | Guodong Wang Jianchun Jiang Kang Sun Jianzhong Wu | 2018 | Chinese Journal of Chemical Engineering2018，26，3： | 3 |
| 4 | Primary Studies on the Microbial Fermentation of 10-Hydroxy-2-Decenoic Acid By Candida BH002显示文摘Fermentation technology of Candida BH002, a 10-hydroxy-2-decenoic acid producing microorganism, was primarilystudied in this paper. Results showed that the optimum medium for the batch-fed fermentation was: sucrose 4%, ammoniumsulfate 0.3%, peptone 0.1%, beef extract 0.1%, dipotassium hydrogen phosphate 0.2%, royal jelly 0.5%, magnesium sulfate0.05%, ferrous sulfate 0.001% and CoCl2 0.001% and pH 7.0. The optimum initial pH value, dissoluble oxygen and reducingsugar concentration were 7.0, 25ml/250ml and 7.0% respectively. Meanwhile, the effects of carbon source and metal ions onthe 10-hydroxy-2-decenoic acid biosynthesis were also studied primarily. | Yongxin Kang Bailin Li Guodong FanSchool of Food Science and Technology Shanghai Fisheries University Shanghai 200090 | 2002 | 食品科学2002，23，8： | 2 |
| 5 | Tracking Survey of Immune Effects of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome (HP-PRRS) in Changping District, Beijing City显示文摘The epidemiology of highly pathogenic porcine reproductive and respiratory syndrome( HP-PRRS) in Changping District,Beijing City was investigated from 2010 to 2015. Through statistics of vaccine,immune procedure and antibody levels,the epidemic prevention effect of HP-PRRS in Changping District was scientifically assessed. | Xing Guodong Lv Yanqiu Qiu Hailian Gao Xiaobo Zhang Yichi Wang Yuewei Kang Xiaojie | 2017 | Animal Husbandry and Feed Science2017，9，5： | 2 |
| 6 | Regulation of the stability and ABA import activity of NRT1.2/NPF4.6 by CEPR2-mediated phosphorylation in Arabidopsis显示文摘Abscisic acid(ABA)transport plays an important role in systemic plant responses to environmental factors.However,it remains largely unclear about the precise regulation of ABA transporters in plants.In this study,we show that the C-terminally encoded peptide receptor 2(CEPR2)directly interacts with the ABA transporter NRT1.2/NPF4.6.Genetic and phenotypic analyses revealed that NRT1.2/NPF4.6 positively regulates ABA response and that NRT1.2/NPF4.6 is epistatically and negatively regulated by CEPR2.Further biochemical assays demonstrated that CEPR2 phosphorylates NRT1.2/NPF4.6 at serine 292 to promote its degradation under normal conditions.However,ABA treatment and non-phosphorylation at serine 292 prevented the degradation of NRT1.2/NPF4.6,indicating that ABA inhibits the phosphorylation of this residue.Transport assays in yeast and Xenopus oocytes revealed that non-phosphorylated NRT1.2/NPF4.6 had high levels of ABA import activity,whereas phosphorylated NRT1.2/NPF4.6 did not import ABA.Analyses of complemented nrt1.2 mutants that mimicked non-phosphorylated and phosphorylated NRT1.2/NPF4.6 confirmed that non-phosphorylated NRT1.2S292A had high stability and ABA import activity in planta.Additional experiments showed that NRT1.2/NPF4.6 was degraded via the 26S proteasome and vacuolar degradation pathways.Furthermore,we found that three E2 ubiquitin-conjugating enzymes,UBC32,UBC33,and UBC34,interact with NRT1.2/NPF4.6 in the endoplasmic reticulum and mediate its ubiquitination.NRT1.2/NPF4.6 is epistatically and negatively regulated by UBC32,UBC33,and UBC34 inplanta.Taken together,these results suggest that the stability and ABA import activity of NRT1.2/NPF4.6 are precisely regulated by its phosphorylation and degradation in response to environmental stress. | Lei Zhang Zipeng Yu Yang Xu Miao Yu Yue Ren Shizhong Zhang Guodong Yang Jinguang Huang Kang Yan Chengchao Zheng Changai Wu | 2021 | Molecular Plant2021，14，4： | 2 |
| 7 | A novel method ofsurface modification on thin film composite reverse osmosismembrane by grafting poly (ethyleneglycol) 显示文摘 | KANG Guodong LIU Ming LIN Bin | 2007 | Polymer2007，48，5： | 1 |
| 8 | Regulation of the stability and ABA import activity of NRT1.2/NPF4.6 by CEPR2-mediated phosphorylation in Arabidopsis显示文摘(Molecular Plant 14,633–646;April 52021)In Figure 1D in our original manuscript,we demonstrated by the mating-based split ubiquitin system(MbSUS)assay that the functional domains of CEPR2 interact with the loop region of NRT1.2/NPF4.6(NRT1.2loop,aa 232-346).However,the sub-image of-WLU in Figure 1D was mistakenly assembled. | Lei Zhang Zipeng Yu Yang Xu Miao Yu Yue Ren Shizhong Zhang Guodong Yang Jinguang Huang Kang Yan Chengchao Zheng Changai Wu | 2022 | Molecular Plant2022，15，10： | 1 |
| 9 | Cryospheric change in China显示文摘 | Xin Li Guodong Cheng Huijun Jin Ersi Kang Tao Che Rui Jin Lizong Wu Zhuotong Nan Jian Wang Yongping Shen | 2008 | Global and Planetary Change2008，，3： | 1 |
| 10 | Application and modification of poly ( vinylidene fluoride) (PVDF) membranes-A review 显示文摘 | Kang Guodong Cao Yiming | 2014 | Journal of Membrane Science2014，463，： | 1 |
| 11 | A novel method of surface modification on thin-film composite reverse osmosis membrane by grafting poly(ethylene glycol)显示文摘 | KANG Guodong LIU Ming LIN Bin | 2007 | Polymer2007，48，5： | 1 |
| 12 | Effect of climate change over the past half century on the distribution, extent and NPP of ecosystems of Inner Mongolia 显示文摘 | ZHANG Guoguang KANG Yumei HAN Guodong | 2011 | Global Change Biology2011，17，1： | 1 |
| 13 | A novel method of surface modification on thin-film composite RO membrane by grafting poly (ethylene glycol)显示文摘 | Guodong Kang Ming Liu Bin Lin | 2007 | Polymer2007，，48： | 1 |
| 14 | Development of antifouling reverse osmosis membranes for water treatment: a review 显示文摘 | Guodong Kang Yiming Cao | 2012 | Water Research2012，46，3： | 1 |
| 15 | Application and modification of poly(vinylidene fluoride)(PVDF) membranes-A review显示文摘 | Kang Guodong Cao Yiming | 2014 | Journal of Membrane Science2014，463，： | 1 |
| 16 | Coordination Effect-Promoted Durable Ni(OH)_(2) for Energy-Saving Hydrogen Evolution from Water/ Methanol Co-Electrocatalysis显示文摘Electrocatalytic water splitting is a viable technique for generating hydrogen but is precluded from the sluggish kinetics of oxygen evolution reactions(OER).Small molecule oxidation reactions with lower working potentials,such as methanol oxidation reactions,are good alternatives to OER with faster kinetics.However,the typically employed Ni-based electrocatalysts have poor activity and stability.Herein,a novel three-dimensional(3D)-networking Modoped Ni(OH)_(2) with ultralow Ni-Ni coordination is synthesized,which exhibits a high MOR activity of 100 mA cm^(−2) at 1.39 V,delivering 28 mV dec^(−1) for the Tafel slope.Meanwhile,hydrogen evolution with value-added formate co-generation is boosted with a current density of more than 500 mA cm^(−2) at a cell voltage of 2.00 V for 50 h,showing excellent stability in an industrial alkaline concentration(6 M KOH).Mechanistic studies based on density functional the-ory and X-ray absorption spectroscopy showed that the improved performance is mainly attributed to the ultralow Ni-Ni coordination,3D-networking structures and Mo dopants,which improve the catalytic activity,increase the active site density and strengthen the Ni(OH)_(2)3D-networking structures,respectively.This study paves a new way for designing electrocatalysts with enhanced activity and durability for industrial energy-saving hydrogen production. | Guodong Fu Xiaomin Kang Yan Zhang Xiaoqiang Yang Lei Wang Xian-Zhu Fu Jiujun Zhang Jing-Li Luo Jianwen Liu | 2022 | Nano-Micro Letters2022，14，12： | 1 |
| 17 | Surface modifica- tion of a commercial thin film composite polyamide reverse osmosis membrane by carbodiimide-induced grafting with poly (ethylene glycol) derivatives显示文摘 | Kang Guodong Yu Haijun Liu Zhongnan | 2011 | Desalination2011，275，123： | 1 |
| 18 | A model for simulating the response of runoff from the mountainous watersheds of inland river basins in the arid area of northwest China to climatic changes显示文摘 | Ersi Kang Guodong Cheng Yongchao Lan Huijun Jin | 1999 | Science in China Series D: Earth Sciences1999，，1： | 1 |
| 19 | Enhancing Antifoul- ing Property of Polysulfone Ultrafiltration Membrane by Grafting Zwitterionic Copolymer via UV-Initiated Polymerization显示文摘 | Yu H Gao Yiming Kang Guodong | 2009 | Jour- nal of Membrane Science2009，342，： | 1 |
| 20 | Enhancingantifouling property of polysulfone ultrafiltration membrane bygrafting zwitterionic copolymer via UV-initiated polymerization显示文摘 | YU Haijun CAO Yiming KANG Guodong | 2009 | Journal of Membrane Science2009，342，12： | 1 |
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