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36篇 您的检索式：作者名="Karsten C"

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	题名	作者	年代	出处	被引量
1	Docosahexaenoic acid suppresses arachidonic acid-induced proliferation of LS-174T human colon carcinoma cells显示文摘AIM:To investigate the impact of arachidonic acid (AA) and docosahexaenoic acid (DHA) and their combination on colon cancer cell growth.METHODS:The LS-174T colon cancer cell line was used to study the role of the prostaglandin precursor AA and the omega-3 polyunsaturated fatty acid DHA on cell growth. Cell viability was assessed in XTT assays. For analysis of cell cycle and cell death,flow cytometry and DAPI staining were applied. Expression of cyclooxygenase-2 (COX-2),p21 and bcl-2 in cells incubated with AA or DHA was examined by real-time RT-PCR. Prostaglandin E2 (PGE2) generation in the presence of AA and DHA was measured using a PGE2-ELISA.RESULTS:AA increased cell growth,whereas DHAreduced viability of LS 174T cells in a time-and dose-dependent manner. Furthermore,DHA down-regulated mRNA of bcl-2 and up-regulated p21. Interestingly,DHA was able to suppress AA-induced cell proliferation and significantly lowered AA-derived PGE2 formation. DHA also down-regulated COX-2 expression. In addition to the effect on PGE2 formation,DHA directly reduced PGE2-induced cell proliferation in a dose-dependent manner. CONCLUSION:These results suggest that DHA can inhibit the pro-proliferative effect of abundant AA or PGE2.	Piet Habbel Karsten H Weylandt Katja Lichopoj Johannes Nowak Martin Purschke Jing-Dong Wang Cheng-Wei He Daniel C Baumgart Jing X Kang	2009	World Journal of Gastroenterology2009，15，9：	2
2	Biosynthesis of the Lantibiotic Mersacidin :Organization of a type B lantibiotic gene cluster显示文摘	Karsten A Andre G Claudia C	2000	Appl Environ Microbiol2000，66，6：	1
3	Salinity tolerance biliprotein, and floridoside content of Compsopogon coeruleus ( Rho- dophyta) 显示文摘	GLAZER A N CHAN C E KARSTEN U	1994	Journal of Phycology1994，30，3：	1
4	Low molecular weight carbohydrates of the Bangiophyeidae (Rhodophyta) 显示文摘	KARSTEN U WEST J A ZUCCARELLO G C	2003	Journal of Phycology2003，39，3：	1
5	Design and manu- facture of a lightweight reflective baffle for the BepiColombo Laser Altimeter显示文摘	Karsten S Sumita C Kurt	2007	Optical Enginee ing2007，46，4：	1
6	Low molecular weight carbohydrate patterns in the Bangiophyceae (Rhodophyta) 显示文摘	KARSTEN U WEST J A ZUCCARELLO G C	1999	Journal of Phycolo- gy1999，35，5：	1
7	Does the lack of mannitol accumulation in an isolate of Rhodella rna~ulata (Rhodellophyceae, Rhodophyta) from the brackish Baltic Sea indicate a stressed population at the distribution limit 显示文摘	NITSCHKE U BOEDEKER C KARSTEN U	2010	Eur J Phycol2010，45，4：	1
8	On tidal resonance in the global ocean and the back-effect of coastal tides upon open-ocean tides显示文摘	ARBIC B K KARSTEN R H GARRETT C	2009	Atmosphere-Ocean2009，47，4：	1
9	Expression and localization of P-glycoprotein in human heart: effects of cardiomyopathy显示文摘	Sperker B Karsten C	2002	J Histochem Cytochem2002，50，：	1
10	A survey of the distribution of UV- absorbing substances in tropical macroalgae 显示文摘	Karsten U Sawall T Wiebcke C	1998	Phycol Res1998，46，：	1
11	Cathepsins B and L activate Ebola but not Marburg virus glycoproteins for effi- cient entry into cell lines and macrophages independent of TMPRSS2 expression显示文摘	Gnirss K Kuhl A Karsten C et O1	2012	Virology2012，424，1：	1
12	Interaction of eukaryotic initiation factor eIF4B with the internal ribosome entry site of foot-and-mouth disease virus is independent of the polypyrimidinetract-binding protein显示文摘	René C Rust Kerstin Ochs Karsten Meyer	1999	J Virol1999，73，7：	1
13	Compound exocytosis of granules in human neutrophils显示文摘	Karsten L Manfred L Jero C	2002	J Leuk Biol2002，71，：	1
14	A splice - site mutation in GABRG2 associated with childhood absence epilepsy and febrile convulsions显示文摘	Kananura C Karsten H Sander T	2002	Arch neurol2002，59，7：	1
15	A new unusual low molecular weight carbohydrate in the red algal genus Hypoglossum (Delesseriaeeae, Ceramiales) and its possible function as an osmolyte 显示文摘	Karsten U West J A Zuccarello G C	2005	Planta2005，222，：	1
16	Building recognition from multi-aspect high-resolution InSAR data in urban areas显示文摘	Antje T Erich C Karsten S	2007	IEEE Transactions on Geoscience and Remote Sensing2007，45，11：	1
17	Highlights in uranium co- ordination chemistry显示文摘	SUZANNE C B KARSTEN M	2008	Structure and Bonding2008，127，2：	1
18	An evaluation of tyramide signal amplification and archived fixed and frozen tissue in microarray gene expression analysis显示文摘	KARSTEN S L VAN D V M SABATTI C	2002	Nucleic Acids Res2002，30，2：	1
19	A survey of the distribution of UV-absorbing substances in tropical macroalgae显示文摘	Karsten U Sawall T Wiencke C	1998	Phycological Research1998，46，：	1
20	Distributed hydrological modelling of the Senegal River Basin — model construction and validation显示文摘	Jens Andersen Jens C Refsgaard Karsten H Jensen	2001	Journal of Hydrology2001，，3：	1

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