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| 1 | 美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。 | Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) | 2012 | 中华神经科杂志2012，45，5： | 22 |
| 2 | Reproducibility of the diagnosis of dysplasia in Barrett esophagus: A reaffirmation显示文摘 | Elizabeth Montgomery Mary P Bronner John R Goldblum Joel K Greenson Marian M Haber John Hart Laura W Lamps Gregory Y Lauwers Audrey J Lazenby David N Lewin Marie E Robert Alicia Y Toledano Yu Shyr Kay Washington | 2001 | Human Pathology2001，，4： | 3 |
| 3 | Can Mutual Funds Outguess the Market? 显示文摘 | Jack L Treynor Kay K Mazuy | 1966 | Havard Business Review1966，44，4： | 1 |
| 4 | Penetrating the cycle of sustained conflict 显示文摘 | KAYE K | 1991 | Family Business Review1991，，4： | 1 |
| 5 | A role for CAP,a novel,multifunctional Src homology 3 domain-containing protein in formation of actin stress fibers and focal adhesions显示文摘 | RIBON V HERRERA R KAY B K | 1998 | J Biol Chem1998，273，7： | 1 |
| 6 | Circadian rhythm genetics: from flies to mice to humans显示文摘 | Wager-Smith K Kay SA | 2000 | Nat Genet2000，26，1： | 1 |
| 7 | The sequence of the rice phytochrome gene显示文摘 | Kay S A Keith B Shinozaki K | | 0，，： | 1 |
| 8 | ACR/EULAR 2010 rheumatoid arthritis classification criteria显示文摘 | Kay J Upehurch K S | 2012 | Rheumatology(Oxford)2012，51，6： | 1 |
| 9 | Carbapenem-resistant Enterobacteriaceae: a review of treatment and outcomes显示文摘 | van Duin D Kaye K S Neuner E A | 2013 | DiangMicrobiollnfectDis2013，75，2： | 1 |
| 10 | Carcinoid syn drome and perioperative anesthetic eonsiderations显示文摘 | Mancuso K Kaye AD Boudreaux JP | 2011 | J Clin Anesth2011，23，4： | 1 |
| 11 | Conversion of light to electricity by cis-X2 bis (2,2-biphyridyl-4,4-dicarboxylate)rutheninm (Ⅱ) charge-transfer sensitizers (X=CI^-,Br,I^-,CN^-,and SCN) on nanocrystalline TiO2 electrodes 显示文摘 | NAZERUDD1N M K KAY A RADICIO I | 1993 | J Am Ceram Soc1993，115，14： | 1 |
| 12 | Conversion of light to electricity by cis-X2 Bis (2,2'-bipyidyl-4,4'-dicaboxylate) ruthenium charge-transfer sensitizes (X = Cl-,Bt-,I-,CN-and SCN-) on nanocrystalline TiO2 electrodes显示文摘 | Nazeetuddin M K Kay A Rodicicio I | 1993 | Am Chem Soc1993，115，： | 1 |
| 13 | Hepatocyte transplantation: clinical and experimental application显示文摘 | Ohashi K Park F Kay MA | 2001 | J Mol Meal2001，79，11： | 1 |
| 14 | Gender Recogni- tion from Point-light Walkers 显示文摘 | Pollick F Kay J Heim K | 2005 | Journal of Experi- mental Psychology: Perception & Psychophysics2005，47，1： | 1 |
| 15 | Conversion of light to electricity by cis-X2Bis (2,2'-bipyridyl-4,4'-dicarboxylate)ruthenium (Ⅱ) charge-transfer sensitizers (X=C1-,Br-,I-,CN-,and SCN-) on nanocrystalline TiO2 electrodes显示文摘 | NAZEERUDDIN M K KAY A RODICIO I | 1993 | Journal of the American Chemical Society1993，115，14： | 1 |
| 16 | The Linguistic Significance of the Meanings of Basic Color Terms显示文摘 | Paul Chad K McDaniel | 1978 | Language1978，54，3： | 1 |
| 17 | Perception and valuations of community-based education and service by alumni at Makerere University College of Health Sciences显示文摘 | Andrew Mwanika Isaac Okullo Dan K Kaye | | 0，，01： | 1 |
| 18 | Radioactive stents delay but do not prevent in-stent neointimal hyperplasia显示文摘 | Kay IP Wardeh A J Kozuma K | 2001 | Circulation2001，103，： | 1 |
| 19 | The linguistic significance of the meanings of basic color terms显示文摘 | Kay Paul & C K McDaniel | 1978 | Language1978，54，5： | 1 |
| 20 | The effect of increasing age on the risk of surgical site infection显示文摘 | Kaye KS Schmit K Pieper C | 2005 | J Infect Dis2005，191，7： | 1 |
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