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| 1 | Excess Molar Volumes and Excess Logarithm Viscosities for Binary Mixtures of the Ionic Liquid 1-Butyl-3-methylimidazolium Hexaflurophosphate with Some Organic Compounds显示文摘 | Jianji Wang Anlian Zhu Yang Zhao Kelei Zhuo | 2005 | Journal of Solution Chemistry2005，，5： | 1 |
| 2 | Excess Molar Volumes and Excess Logarithm Viscosities for Binary Mixtures of the Ionic Liquid 1-Butyl-3-methylimidazolium Hexaflurophosphate with Some Organic Compounds显示文摘 | Jianji Wang Anlian Zhu Yang Zhao Kelei Zhuo | 2005 | Journal of Solution Chemistry2005，，5： | 1 |
| 3 | Excess molar volumes and excess logarithm viscosities for binary mixtures of the ionic liquid 1-butyl-3-rnethylirnidazolium hexaflurophosphate with some organic compounds 显示文摘 | Wang Jianji Zhu Anlian Zhao Yang Zhu Kelei | 2005 | Journal of Solution Chemistry2005，34，5： | 1 |
| 4 | Nitrogen-doped porous carbon nanosheets as both anode and cathode for advanced potassium-ion hybrid capacitors显示文摘Potassium-ion hybrid capacitors(PIHCs)as a burgeoning research hotspot are an ideal replacement for lithium-ion hybrid capacitors(LIHCs).Here,we report nitrogen-doped porous carbon nanosheets(NPCNs)with enlarged interlayer spacing,abundant defects,and favorable mesoporous structures.The structural changes of NPCNs in potassiation and depotassiation processes are analyzed by using Raman spectroscopy and transmission electron microscopy.Due to the unique structure of NPCNs,the PIHC device assembled using NPCNs as both the anode and cathode material(double-functional self-matching material)exhibits a superior energy density of 128 Wh kg^(-1)with a capacity retention of 90.8%after 9000 cycles.This research can promote the development of double-functional self-matching materials for hybrid energy storage devices with ultra-high performance. | Quanzhou Du Yuhua Zhao Yujuan Chen Jianming Liu Huanhuan Li Guangyue Bai Kelei Zhuo Jianji Wang | 2023 | Green Energy & Environment2023，8，2： | 1 |
| 5 | Prediction and verifcation of the key ingredients and molecular targets of Guizhi Fuling capsule against tumour metastasis and resistance显示文摘Purpose:The well-known traditional Chinese formula Guizhi Fuling capsule(GFC)has been reported to reverse ovarian cancer drug resistance.Extrachromosomal DNA(ecDNA)plays an important role in tumour metastasis and resistance.The purpose of this study was to investigate the potential mechanisms by which GFC blocks tumour metastasis and reverses drug resistance by targeting ecDNA.Methods:CNKI and PubMed were used to obtain pharmacokinetic research data on GFC in rats,and the bioactive ingredients detected in rat serum or plasma were collected.Network databases were used to screen the abnormally expressed genes in ecDNA,tumour metastasis genes,resistance genes,and the active ingredient targets of GFC.The KOBAS3.0 database was used to enrich the KEGG pathways and GO functions;the STRING platform was used to construct the core protein interaction network;and the molecular docking online tool SwissDock was used to analyse the binding activity of the core targets and the active ingredients.RT-qPCR,Western blotting and laser confocal microscopy were used to verify the efect of the sera containing GFC on ecDNA,mRNA and protein expression of key targets.Results:Twenty-three bioactive ingredients of GFC were retrieved from PubMed and CNKI.Nine shared targets were simultaneously involved in abnormal genes in ecDNA,tumour metastasis and resistance and the active ingredient targets of GFC.GO functional analysis indicated that the cotargets involved cell proliferation,apoptotic regulation,nuclear functions,etc.The potential pathways involved in the reversal of tumour metastasis and drug resistance of GFC were the PI3K-Akt signalling,cancer,and platinum drug resistance pathways.Three shared proteins targeting ecDNA(AKT1,EGFR and MYC)stand out from the top 20 PPI targets,and all of the bioactive ingredients of GFC have strong binding afnity to the three proteins.The active ingredients can reduce the expression of MYC,EGFR and AKT1 mRNA and protein and the amount of ecDNA in drug-resistant OC cells.Conclusions:GFC targeting ecDNA to reverse tumour metastasis and drug resistance has the characteristics of multiple ingredients,multiple targets,and multiple pathways,which provides a new perspective for the development of new drugs targeting ecDNA to beneft tumour treatment. | Li Han Qin Lv Xiaojuan Guo Kelei Guo Ruijuan Du Fubo Li Xulin Zhao Hua Bian | 2022 | Holistic Integrative Oncology2022，1，1： | 0 |
| 6 | Structural basis of sRNA RsmZ regulation of Pseudomonas aeruginosa virulence显示文摘Dear Editor,Pseudomonas aeruginosa is a ubiquitous Gram-negative opportunistic bacterium that notoriously causes infections with a high mortality rate in hospitalized patients,especially those with compromised immune systems.P.aeruginosa can cause acute infections that are typically associated with the cytotoxins secreted by the type Ⅲ secretion system(T3ss). | Xinyu Jia Zhiling Pan Yang Yuan Bingnan Luo Yongbo Luo Sunandan Mukherjee Guowen Jia Liu Liu Xiaobin Ling Xiting Yang Zhichao Miao Xiawei Wei Janusz M.Bujnicki Kelei Zhao Zhaoming Su | 2023 | Cell Research2023，33，4： | 0 |
| 7 | Key gene networks that control magnetosome biomineralization in magnetotactic bacteria显示文摘Magnetotactic bacteria(MTB)are a group of phylogenetically and morphologically diverse prokaryotes that have the capability of sensing Earth's magnetic field via nanocrystals of magnetic iron minerals.These crystals are enclosed within intracellular membranes or organelles known as magnetosomes and enable a sensing function known as magnetotaxis.Although MTB were discovered over half a century ago,the study of the magnetosome biogenesis and organization remains limited to a few cultured MTB strains.Here,we present an integrative genomic and phenomic analysis to investigate the genetic basis of magnetosome biomineralization in both cultured and uncultured strains from phylogenetically diverse MTB groups.The magnetosome gene contents/networks of strains are correlated with magnetic particle morphology and chain configuration.We propose a general model for gene networks that control/regulate magnetosome biogenesis and chain assembly in MTB systems. | Peiyu Liu Yue Zheng Rongrong Zhang Jinling Bai Kelei Zhu Karim Benzerara Nicolas Menguy Xiang Zhao Andrew P.Roberts Yongxin Pan Jinhua Li | 2023 | National Science Review2023，10，1： | 0 |
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