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| 1 | 热处理豆粕饲喂生长猪的氨基酸消化率显示文摘为测定热处理对豆粕(SBM)表观回肠消化率和标准回肠消化率(SID)的影响,本试验将常规去壳豆粕(48.5%蛋白)分成4组,一份未经额外热处理,一份在125℃下高压蒸汽处理15 min,一份在125℃下高压蒸汽处理30 min,另一份在125℃下烘箱烘干30 min。制定四种豆粕-玉米淀粉型日粮配方,且每个配方只能使用上述四种豆粕中的一种,作为每种日粮中唯一氨基酸来源。用无氮日粮配方来估算基础内源性氨基酸损失。分别在初始体重为(25.3±2.0)kg的10头阉公猪回肠末端安装一个T-型瘘管。采用5×5拉丁方设计法,将试验猪分成5个日粮处理组,5个重复处理周期。每个处理周期持续7 d,在第6天和第7天收集回肠食糜。试验结果表明,随着高压蒸汽处理时间(0~30 min)的延长,蛋白质和所有氨基酸的表观回肠消化率和标准回肠消化率呈线性降低(P<0.01)。糠氨酸含量和豆粕样品的颜色表明高压蒸汽处理导致豆粕产生美拉德反应。然而,125℃烘箱干燥30min并未改变豆粕中蛋白和氨基酸标准回肠消化率,也没有改变SBM的糠氨酸含量(P>0.10),且烘箱处理的样品颜色表明该样品并未受到热处理破坏。总之,热蒸汽处理时间从0 min增至30 min,高压蒸汽处理豆粕的氨基酸消化率呈线性降低,降低原因很可能是由于125℃高压蒸汽处理导致豆粕产生美拉德反应。 | González-Vega J C Kim B G Htoo J K Lemme A Stein H H | 2015 | 中国饲料2015，，24： | 8 |
| 2 | Appropriateness of systemic treatments in unresectable metastatic well-differentiated pancreatic neuroendocrine tumors显示文摘AIM:To evaluate systemic treatment choices in unresectable metastatic well-differentiated pancreatic neuroendocrine tumors(PNETs)and provide consensus treatment recommendations.METHODS:Systemic treatment options for pancreatic neuroendocrine tumors have expanded in recent years to include somatostatin analogs,angiogenesis inhibitors,inhibitors of mammalian target of rapamycinand cytotoxic agents.At this time,there is little data to guide treatment selection and sequence.We therefore assembled a panel of expert physicians to evaluate systemic treatment choices and provide consensus treatment recommendations.Treatment appropriateness ratings were collected using the RAND/UCLA modified Delphi process.After studying the literature,a multidisciplinary panel of 10 physicians assessed the appropriateness of various medical treatment scenarios on a 1-9 scale.Ratings were done both before and after an extended discussion of the evidence.Quantitative measurements of agreement were made and consensus statements developed from the second round ratings.RESULTS:Specialties represented were medical and surgical oncology,interventional radiology,and gastroenterology.Panelists had practiced for a mean of15.5 years(range:6-33).Among 202 rated scenarios,disagreement decreased from 13.2%(26 scenarios)before the face-to-face discussion of evidence to 1%(2)after.In the final ratings,46.5%(94 scenarios)were rated inappropriate,21.8%(44)were uncertain,and30.7%(62)were appropriate.Consensus statements from the scenarios included:(1)it is appropriate to use somatostatin analogs as first line therapy in patients with hormonally functional tumors and may be appropriate in patients who are asymptomatic;(2)it is appropriate to use everolimus,sunitinib,or cytotoxic chemotherapy therapy as first line therapy in patients with symptomatic or progressive tumors;and(3)beyond first line,these same agents can be used.In patients with uncontrolled secretory symptoms,octreotide LAR doses can be titrated up to 60 mg every4 wk or up to 40 mg every 3 or 4 wk.CONCLUSION:Using the Delphi process allowed physician experts to systematically obtain a consensus on the appropriateness of a variety of medical therapies in patients with PNETs. | Jonathan R Strosberg George A Fisher Al B Benson Lowell B Anthony Bulent Arslan John F Gibbs Edward Greeno Renuka V Iyer Michelle K Kim William J Maples Philip A Philip Edward M Wolin Dasha Cherepanov Michael S Broder | 2015 | World Journal of Gastroenterology2015，21，8： | 2 |
| 3 | 由磁共振成像评估的主动脉弓脉搏波传导速度是心血管事件的预测因子:多种族动脉粥样硬化研究显示文摘通过磁共振成像评估的主动脉弓脉搏波传导速度(pulse wave velocity,PWV)对心血管病事件的预测价值尚未完全确定。为了评估多种族动脉粥样硬化研究(multi-ethnic study of atherosclerosis,MESA)受试者中主动脉弓PWV与心血管病的关系,Ohyama等纳入3527例MESA受试者[基线时平均年龄为(62±10)岁,47%为男性], | 刘莉 叶鹏 Ohyama Y Ambale-Venkatesh B Noda C Kim JY Tanami Y Teixido-Tura G Chugh AR Redheuil A Liu CY Wu CO Hundley WG Bluemke DA Guallar E Lima JAC | 2017 | 中华高血压杂志2017，25，8： | 2 |
| 4 | AC impedance study on the atmo49spheric corrosion of aluminum under periodic wet-dry conditions显示文摘 | EL-Mahdya Gamal A Kim Kwang B | 2004 | Electrochimica Acta2004，49，： | 1 |
| 5 | Resveratrol inhibits cell proliferation and induces apoptosis of human breast carcinoma MCF-7 cells显示文摘 | Kim Y A Choi B T Lee Y T | 2004 | Oncol Rep2004，11，2： | 1 |
| 6 | Cholangioearcinoma:pictorial essay of CT and cholangiographic findings显示文摘 | Han J K Choi B I Kim A Y | 2002 | Radiographics2002，22，1： | 1 |
| 7 | Clinical trials of vascular brachy-therapy for instent restenosis : update显示文摘 | Ajani A Kim HS Waksman B | 2001 | Cardiovasc Badiat Med2001，2，： | 1 |
| 8 | Modified Hodge and EDTA-disk synergy tests to screen metallo-beta-lactamase-producing strains of Pseudomonas and Acinetobacter species显示文摘 | Lee K Y·Chong H·B·Shin Y·A·Kim D·Yong and J·H·Yum | 2001 | Clin Microbiol Infect2001，7，： | 1 |
| 9 | Direct determination of the t matrix from a mom impedance matrix computed using the Rao Wilton Glisson basis function显示文摘 | Kim K T Kramer B A | 2013 | IEEETranson Antennas Propagation2013，61，53： | 1 |
| 10 | Immunogenicity of an adenoviral- based middle east respiratory syndrome coronavirus vaccine in balb/c mice显示文摘 | Kim E Okada K Kenniston T Raj V S A1Hajri M M Farag E A AIHairi F Osterhaus A D Haagmans B L Gambotto A | 2014 | Vaccine2014，32，45： | 1 |
| 11 | A Comparison of Oven-cured and Induction-cured Adhesively Bonded Composite Joints显示文摘 | Mahdi S Kim H J Gama B A | 2003 | Journal of Composite Materials2003，37，6： | 1 |
| 12 | Influence of MF Pretreatment on NF performance for aqueous solution containing particles and an organic foulant显示文摘 | Bruggen B V Kim J H DiGiano F A | 2004 | Sep Purif Technol2004，36，： | 1 |
| 13 | Prognostic impact of clinicopathologic parameters in stage Ⅱ / Ⅲ breast cancer treated with neoadjuvant docetaxel and doxorubicin chemotherapy: paradoxical features of the triple negative breast cancer显示文摘 | Keam B Im S A Kim H J | 2007 | BMC Cancer2007，1，： | 1 |
| 14 | Sensing of lead ions by a carboxylate-substituted PPE: Multivalency effects显示文摘 | Kim I B Dunkhorst A Gilbert J | 2005 | Macromolecules2005，38，11： | 1 |
| 15 | In situ microextraction method to determine the viscosity of biofluid in threadlike structures on the surfaces of mammalian organs显示文摘 | Sung B Kim MS Corrigan A | 2009 | Phys Rev E2009，79，2： | 1 |
| 16 | Elasto-optic alignment of birefringent axes in polarization-holding optical fiber显示文摘 | CARRARA S L A KIM B Y SHAW H J | 1986 | Optics Letters1986，11，7： | 1 |
| 17 | High-level expression of an antimicrobial peptide histonin as a natural form by multimerization and furin-mediatedcleavage显示文摘 | Jung Min Kim S A Jang B J Yu | 2008 | Appl Microbiol Biotechnol2008，78，： | 1 |
| 18 | Nonlinear flight control using neural networks显示文摘 | Kim B S Calise A J | 1997 | Joumal of Guidance Control and Dynamics1997，20，1： | 1 |
| 19 | Molecular genetiC diversity and population structure in Lycium accessions using SSR markers显示文摘 | Zhao W G Chung J W Cho Y I Rha W H Lee G A Ma K H Han S H Bang K H Park C B Kim S M Park Y J | 2010 | C R Bioi2010，333，： | 1 |
| 20 | Imaging of the seminal vesicle and vas deferens 显示文摘 | Kim B Kawashima A Ryu J A | 2009 | Radiographics2009，29，4： | 1 |
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