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184篇 您的检索式：作者名="Klassen D"

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	题名	作者	年代	出处	被引量
1	Alcohol metabolites and lipopolysaccharide: Roles in the development and/or progression of alcoholic liver disease显示文摘The onset of alcoholic liver disease (ALD) is initiated by different cell types in the liver and a number of different factors including: products derived from ethanol-induced inflammation, ethanol metabolites, and the indirect reactions from those metabolites. Ethanol oxidation results in the production of metabolites that have been shown to bind and form protein adducts, and to increase inflammatory, fibrotic and cirrhotic responses. Lipopolysaccharide (LPS) has many deleterious effects and plays a significant role in a number of disease processes by increasing inflammatory cytokine release. In ALD, LPS is thought to be derived from a breakdown in the intestinal wall enabling LPS from resident gut bacterial cell walls to leak into the blood stream. The ability of adducts and LPS to independently stimulate the various cells of the liver provides for a two-hit mechanism by which various biological responses are induced and result in liver injury. Therefore, the purpose of this article is to evaluate the effects of a two-hit combination of ethanol metabolites and LPS on the cells of the liver to increase inflamma-tion and fi brosis, and play a role in the development and/or progression of ALD.	Courtney S Schaffert Michael J Duryee Carlos D Hunter Bartlett C Hamilton 3rd Amy L DeVeney Mary M Huerter Lynell W Klassen Geoffrey M Thiele	2009	World Journal of Gastroenterology2009，15，10：	20
2	National profile of practice patterns for hemodialysis vascular access in the united states显示文摘	Reddan D Klassen P Frankfield	2002	J Am Soc Nephrol2002，13，8：	1
3	At- mospheric Corrosivity Modeling-A Review显示文摘	ROBERGE P R KLASSEN R D HABERECHT P W	2002	Materials & Design2002，23，3：	1
4	Atmospheric corrosivity modeling- a review显示文摘	Roberge P R Klassen R D	2002	Materials and Design2002，23，：	1
5	Integrating environmental issues into the mainstream: an agenda for research in operations management显示文摘	Klassen R D	1999	Journal of Operations Management1999，17，：	1
6	Histologic grading of pancress acute allograft rejection in percutaneous needle biopsies 显示文摘	Drachenherg C Klassen D Bartlett S	1996	Transplant Proc1996，28，1：	1
7	Sustainable Supply Chains:An Introduction显示文摘	Jonathan D Linton Robert Klassen Vaidyanathan Jayaraman		0，，06：	1
8	Environmental Management in Operations:The Selection of Environmental Technologies显示文摘	KLASSEN R D WHYBARK D C	1999	Decision Sciences1999，30，3：	1
9	Aerosol transport modeling as an aid to understanding atmospheric corrosivity patterns显示文摘	Klassen R D Roberge P R	1999	Materials and Design1999，20，：	1
10	Sustainable supply chains: An introduction 显示文摘	Linton J D Klassen R Jayaraman V	2007	Journal of Operations Management2007，25，10：	1
11	Sustainable Supply Chains: An Introduction 显示文摘	Linton J D Klassen R Jayaraman V	2007	Journal of Operations Management2007，，6：	1
12	The impact of environmental technologies on manufacturing performance显示文摘	Klassen R D Whybark D C	1999	Academy of Management Journal1999，40，6：	1
13	National ESRD CPM Work Group:National profile of practice patterns for hemodialysis vascular access in the United States显示文摘	Reddan D Klassen P Frankenfield DL	2002	J Am Soc Nephrol2002，13，：	1
14	The Impact of Environmental Technologies on Manufacturing Performance 显示文摘	Klassen R D Whybark D C	1999	Academy of Management Journal1999，42，6：	1
15	The effectiveness of a proprioceptive balance training program in healthy adolescents显示文摘	EMERY C A CASSIDY J D KLASSEN T	2005	A Cluster Randomized Controlled Trial2005，172，6：	1
16	Atmospheric Corrosivity Modeling a Review 显示文摘	ROBERGE P R KLASSEN R D HABERECHT P W	2002	Materials & Design2002，23，3：	1
17	Laparoscopic sleeve gastrectomy: perioperative outcomes, weight loss and impact on type 2 diabetes mellitus over 2 years 显示文摘	Hoogerboord M Wiebe S Klassen D	2014	Can J Surg2014，57，2：	1
18	Collaboration and Evalu- ation in the Supply Chain: The Impact on Plant - level Environmental Investment显示文摘	Klassen R D Vachon S	2003	Production and Opera- tions Management2003，12，3：	1
19	Atmospheric Corrosively Modeling-a Review 显示文摘	Roberge P R Klassen R D Haberecht P W	2002	Materials and Design2002，23，：	1
20	H2 02 Determination by the I Method and by KMnO4 Titration 显示文摘	Klassen N V Marchington D McGovan H C	1994	Anal Chem1994，66，18：	1

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