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| 1 | Dopamine as a growth differentiation factor in the mammalian brain显示文摘The catecholamine,dopamine,plays an important role in the central nervous system of mammals,including executive functions,motor control,motivation,arousal,reinforcement,and reward.Dysfunctions of the dopaminergic system lead to diseases of the brains,such as Parkinson’s disease,Tourette’s syndrome,and schizophrenia.In addition to its fundamental role as a neurotransmitter,there is evidence for a role as a growth differentiation factor during development.Recent studies suggest that dopamine regulates the development ofγ-aminobutyric acidergic interneurons of the cerebral cortex.Moreover,in adult brains,dopamine increases the production of new neurons in the hippocampus,suggesting the promoting effect of dopamine on proliferation and differentiation of neural stem cells and progenitor cells in the adult brains.In this mini-review,I center my attention on dopaminergic functions in the cortical interneurons during development and further discuss cell therapy against neurodegenerative diseases. | Koji Ohira | 2020 | Neural Regeneration Research2020，15，3： | 4 |
| 2 | Vitamin D receptor expression is associated with colon cancer in ulcerativecolitis显示文摘 | Koji Wada Hiroaki Tanaka Kiyoshi Maeda Toru Inoue Eiji Noda Ryosuke Amano Naoshi Kubo Kazuya Muguruma Nobuya Yamada Masakazu Yashiro Tetsuji Sawada Bunzo Nakata Masaichi Ohira Kosei Hirakawa | 2009 | Oncology Reports2009，，5： | 2 |
| 3 | BDNF pro-peptide:a novel synaptic modulator generated as an N-terminal fragment from the BDNF precursor by proteolytic processing显示文摘Most growth factors are initially synthesized as precursors and it was cleaved into bioactive mature domain and pro-domain.However,compared with the expression and function of bioactive mature domain,the biological role of the pro-domain is poorly understood.Unexpectedly,we found that the pro-domain(or pro-peptide)of brain-derived neurotrophic factor(BDNF),which is well-known neurotrophic factor in brain,has a potential ability to facilitate hippocampal long-term depression.Furthermore,a BDNF polymorphism Val66Met,which substitute valine into methionine at 66 amino acid,impacted the biological activity of the BDNF pro-peptide.We lastly discuss the possible roles of BDNF and its pro-peptide in the generation of neural stem cells and progress of ischemia. | Toshiyuki Mizui Koji Ohira Masami Kojima | 2017 | Neural Regeneration Research2017，12，7： | 2 |
| 4 | Sol–gel synthesis of macro–mesoporous titania monoliths and their applications to chromatographic separation media for organophosphate compounds显示文摘 | Junko Konishi Koji Fujita Kazuki Nakanishi Kazuyuki Hirao Kei Morisato Shota Miyazaki Masayoshi Ohira | 2009 | Journal of Chromatography A2009，，： | 1 |
| 5 | Purifi-cation and storage of ribulose 1,5-bisphos-phate carboxylase from rice leaves显示文摘 | TADAHIKO MAE KOJI OHIRA | 1983 | Plant & Cell Physiol1983，24，6： | 1 |
| 6 | Flelation be- tween Nitrogen and Ribulose -1,5 -bisphosphate Carboxylase in rice leaves from emergence through senescence 显示文摘 | AMANE MAKINO TADAHIKO MAE KOJI OHIRA | 1984 | Plant Cell Physiol1984，25，3： | 1 |
| 7 | Thiamine requirement of two different cultured cell lines of soybean显示文摘 | Makoto Ikedal Kunihiko Ojima Koji Ohira | 1979 | Plant & Cell Physiology1979，20，： | 1 |
| 8 | Difference in cytotoxicity against hepatocellular carcinoma between liver and periphery natural killer cells in humans显示文摘 | Kohei Ishiyama Hideki Ohdan Masahiro Ohira Hiroshi Mitsuta Koji Arihiro Toshimasa Asahara | 2006 | Hepatology2006，，2： | 1 |
| 9 | Possible Regulation of Migration of Intrahepatic Cholangiocarcinoma Cells by Interaction of CXCR4 Expressed in Carcinoma Cells with Tumor Necrosis Factor-α and Stromal-Derived Factor-1 Released in Stroma显示文摘 | Shusaku Ohira Motoko Sasaki Kenichi Harada Yasunori Sato Yoh Zen Kumiko Isse Kazuto Kozaka Akira Ishikawa Koji Oda Yuji Nimura Yasuni Nakanuma | 2006 | The American Journal of Pathology2006，，4： | 1 |
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