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| 1 | Comparison of decompression tubes with metallic stents for the management of right-sided malignant colonic obstruction显示文摘BACKGROUND Emergency surgical resection is a standard treatment for right-sided malignant colonic obstruction; however, the procedure is associated with high rates of mortality and morbidity. Although a bridge to surgery can be created to obviate the need for emergency surgery, its effects on long-term outcomes and the most practical management strategies for right-sided malignant colonic obstruction remain unclear.AIM To determine the appropriate management approach for right-sided malignant colonic obstruction.METHODS Forty patients with right-sided malignant colonic obstruction who underwent curative resection from January 2007 to April 2017 were included in the study.We compared the perioperative and long-term outcomes of patients who received bridges to surgery established using decompression tubes and those created using self-expandable metallic stents(SEMS). The primary outcome was the overall survival duration(OS) and the secondary endpoints were the diseasefree survival(DFS) duration and the preoperative and postoperative morbidity rates. Analysis was performed on an intention-to-treat basis.RESULTS There were 21 patients in the decompression tube group and 19 in the SEMS group. There were no significant differences in the perioperative morbidity rates of the two groups. The OS rate was significantly higher in the decompression tube group than in the SEMS group(5-year OS rate; decompression tube 79.5%,SEMS 32%, P = 0.043). Multivariate analysis revealed that the bridge to surgery using a decompression tube was significantly associated with the OS(hazard ratio, 17.41; P = 0.004). The 3-year DFS rate was significantly higher in thedecompression tube group than in the SEMS group(68.9% vs 45.9%; log-rank test,P = 0.032). A propensity score–adjusted analysis also demonstrated that the prognosis was significantly better in the decompression tube group than in the SEMS group.CONCLUSION The bridge to surgery using trans-nasal and trans-anal decompression tubes for right-sided malignant colonic obstruction is safe and may improve long-term outcomes. | Yoshiyuki Suzuki Konosuke Moritani Yuki Seo Takayuki Takahashi | 2019 | World Journal of Gastroenterology2019，25，16： | 5 |
| 2 | Development of fully automatic vegetable transplanter显示文摘 | Konosuke Tsuga | 2000 | Japan Agricultural Research Quarterly2000，34，1： | 1 |
| 3 | Risk Factors for Postoperative Recurrence in Patients with Pathologically T1 Colorectal Cancer显示文摘 | Shuji Iida Hirotoshi Hasegawa Koji Okabayashi Konosuke Moritani Makio Mukai Yuko Kitagawa | 2012 | World Journal of Surgery2012，，2： | 1 |
| 4 | Follow-up outcomes in patients with negative initial colon capsule endoscopy findings显示文摘BACKGROUND Colon capsule endoscopy(CCE),which became clinically applicable in 2006,is a simple and noninvasive procedure to evaluate colonic diseases;the accuracy of second-generation CCE,introduced in 2009,has dramatically improved.Currently,CCE is used as an alternative method for colorectal cancer screening,as well as for evaluating the mucosal lesions of inflammatory bowel disease,in cases where performing colonoscopy(CS)is difficult.However,the outcomes of CCE are uncertain.AIM To investigate the outcomes of Japanese patients with negative findings(no polyps or colorectal cancer)on initial CCE.METHODS This retrospective,single-center study was conducted at the Endoscopic Center at Aishinkai Nakae Hospital.This study included patients who underwent continuous CCE between November 2013 and August 2019,that exhibited no evidence of polyps or colorectal cancer at the initial CCE,and could be followed up using either the fecal immunochemical test(FIT),CS,or CCE.The observational period,follow-up method,presence or absence of polyps and colorectal cancer,pathological diagnosis,and number of colorectal cancer deaths were evaluated.RESULTS Thirty-one patients(mean age,60.4±15.6 years;range,28–84 years;14 men and 17 women)were enrolled in this study.The reasons for performing the first CCE were screening in 12,a positive FIT in six,lower abdominal pain in nine,diarrhea in two,and anemia in two patients.The mean total water volume at the time of examination was 3460±602 mL(2250–4800 mL),and a total CS was performed in 28 patients(90%).The degree of cleanliness was excellent in 15 patients and good in 16,and no poor cases were observed.No adverse events,such as retention or capsule aspiration,were observed in any of the patients.The mean follow-up period was 3.1±1.5 years(range,0.3–5.5 years).Follow-up included FIT in nine,CS in 20,and CCE in four patients(including duplicate patients).The FIT was positive in two patients,while CS revealed five polyp lesions(three in the ascending colon,one in the transverse colon,and one in the descending colon),with sizes ranging between 2 mm and 8 mm.Histopathological findings revealed a hyperplastic polyp in one patient,and adenoma with low grade dysplasia in four patients;colorectal cancers were not recognized.In the follow-up example by CCE,polyps and colorectal cancer could not be recognized.During the follow-up period,there were no deaths due to colorectal cancer in any of the patients.CONCLUSION We determined the outcomes in patients with negative initial CCE findings. | Konosuke Nakaji Mitsutaka Kumamoto Mikiko Yodozawa Kazuki Okahara Shigeo Suzumura Yukinori Nakae | 2021 | World Journal of Gastrointestinal Endoscopy2021，13，10： | 1 |
| 5 | Development of Fully Automatic Vegetable Transplanter 显示文摘 | Konosuke Tsuga | 2000 | JARQ2000，34，2： | 1 |
| 6 | Acute interstitial nephritis associated with ulcerative colitis显示文摘 | Hirobumi Tokuyama Shu Wakino Konosuke Konishi Akinori Hashiguchi Koichi Hayashi Hiroshi Itoh | 2010 | Clinical and Experimental Nephrology2010，，5： | 1 |
| 7 | Development of zigzag transplanting mechanism for transplanter显示文摘 | Tatsuya Konishi Konosuke Tsuga | 1998 | Japanese Society of Agricultural Machinery1998，60，5： | 1 |
| 8 | Development of fully automatic vegetable transplanter显示文摘 | Konosuke TSUGA | 2000 | JARQ2000，34，1： | 1 |
| 9 | Defective efferocytosis by alveolar macrophages in IPF patients显示文摘 | Konosuke Morimoto William J. Janssen Mayumi Terada | 2012 | Respiratory Medicine2012，，12： | 1 |
| 10 | Development of zigzag transplanting mechanism for transplanter显示文摘 | Tatsuya Konishi Konosuke Tsuga | 1998 | Japanese Society of Agricultural Machinery1998，60，5： | 1 |
| 11 | Phytase of the yeast Arxula adeninivorans显示文摘 | Sano Konosuke Fukuhara Hiroshi Nakamura Yoshihiro | 1999 | Biotechnology Letters1999，21，1： | 1 |
| 12 | Development of fully automatic vegetable transplanter显示文摘 | KONOSUKE T | 2000 | JARQ2000，34，1： | 1 |
| 13 | Enzymatic Production of L-Tryptophan from L- and DL-5- lndolymethylhydantoin by Newly Isolated Bacterium显示文摘 | KONOSUKE S KENZO Y CHIKAHIKO E | 1977 | Agric Biol Chem1977，41，5： | 1 |
| 14 | Preparation of magnetostrictive Fe-Al thin film using by plasma process显示文摘 | Konosuke M Yoshihito M | | Journal of Advanced Science0，17，34： | 1 |
| 15 | Development of fully automatic vegetable transplanter 显示文摘 | Konosuke SUGA | 2000 | Japan Agricultural Research Quarterly2000，34，1： | 1 |
| 16 | Development of fully automatic vegetable transplanter显示文摘 | Konosuke Tsuga | 2000 | Japan Agricultural Research Quarterly2000，34，1： | 1 |
| 17 | Development of fully automatic vegetable transplanter显示文摘 | Konosuke Tsuga | 2000 | Japan Agricultural Research Quarterly2000，34，1： | 1 |
| 18 | Development of fully automatic vegetable transplanter 显示文摘 | Konosuke Tsuga | 2000 | JARQ-Japan Agriculture Research Quarterly2000，34，： | 1 |
| 19 | Mechanical characteristics and microstructure of drawn wire of Ti–29Nb–13Ta–4.6Zr for biomedical applications显示文摘 | Mitsuo Niinomi Toshikazu Akahori Shigeki Katsura Konosuke Yamauchi Michiharu Ogawa | 2006 | Materials Science & Engineering C2006，，1： | 1 |
| 20 | Antarctic Radiosonde Observations Reduce Uncertainties and Errors in Reanalyses and Forecasts over the Southern Ocean:An Extreme Cyclone Case显示文摘Cyclones with strong winds can make the Southern Ocean and the Antarctic a dangerous environment.Accurate weather forecasts are essential for safe shipping in the Southern Ocean and observational and logistical operations at Antarctic research stations.This study investigated the impact of additional radiosonde observations from Research Vessel'Shirase'over the Southern Ocean and Dome Fuji Station in Antarctica on reanalysis data and forecast experiments using an ensemble data assimilation system comprising the Atmospheric General Circulation Model for the Earth Simulator and the Local Ensemble Transform Kalman Filter Experimental Ensemble Reanalysis,version 2.A 63-member ensemble forecast experiment was conducted focusing on an unusually strong Antarctic cyclonic event.Reanalysis data with(observing system experiment)and without(control)additional radiosonde data were used as initial values.The observing system experiment correctly captured the central pressure of the cyclone,which led to the reliable prediction of the strong winds and moisture transport near the coast.Conversely,the control experiment predicted lower wind speeds because it failed to forecast the central pressure of the cyclone adequately.Differences were found in cyclone predictions of operational forecast systems with and without assimilation of radiosonde observations from Dome Fuji Station. | Kazutoshi SATO Jun INOUE Akira YAMAZAKI Naohiko HIRASAWA Konosuke SUGIURA Kyohei YAMADA | 2020 | Advances in Atmospheric Sciences2020，37，5： | 1 |
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